Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (452 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
?-linker
?RIM 2-methoxyestradiol 3T3-L1 A769662 acetyl-CoA activation loop adaptive thermogenesis adenosine monophosphate-activated protein kinase adherent junctions adipocyte adipose tissue AICAR AID Akt AML AMP-activated protein kinase AMP-activated protein kinase (AMPK) AMPK AMPK kinase AS160 assisted reproduction techniques atrophy autophagy beiging CaMKK2 carrier catechol-O-methyltransferase CBS cellular energy sensing chromatin remodeling CML CMML co-expression CREB developmental origins of health and disease (DOHaD) dietary fatty acids differentiation DNA methylation endothelial cells endothelial function endothelial nitric-oxide synthase energy deficiency energy metabolism energy utilization epigenetics epithelial cells exercise fatty acid oxidation fiber-type food intake gestational diabetes mellitus glucose uptake glycogen glycogen storage disease HDAC4/5 HDACs heat shock protein hepatocyte hindlimb suspension histone modification host defense hypertension hypertrophy hypothalamus IL-1? Immediate early genes indirect calorimetry infection insulin signalling ionomycin KATs kidney disease lipid metabolism liver LKB1 macrophages MDCK MDS mechanical unloading medulloblastoma membrane membranes metabolic disease metabolic-inflammation metabolism microarrays mitochondria monocytes motility motor endplate remodeling mTOR mycobacteria MyHC I(?) n/a NAD+ nectin-afadin NLRP3 nutrient-sensing signals nutrigenomics nutrition oxidative stress p70S6K par complex peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) phenylephrine phosphorylation PKA preeclampsia pregnancy proteasome protein acetylation protein kinase B protein synthesis pump regrowth renin-angiotensin system resveratrol signaling sirtuin 1 (SIRT1) skeletal muscle soleus muscle soluble Adenylyl cyclase sonic hedgehog spermatozoa steatosis stress synaptic activation TAK1 TBC1D4 tight junctions transcription transporter ULK vasoconstriction vasodilation ZO-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
Neumann Dietbert
|
||
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
| Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics |
| Autore | Tutone Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (387 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
3CL-Pro
3D-QSAR acetylcholinesterase aging progression mechanism Alzheimer's disease aminophenylbenzamide antibody:antigen interactions antivirals binding free energies binding site binding space carbon nanotubes cholesterol computational biology consensus models COVID-19 COX-2 inhibitors deep learning diabetes docking simulations doxorubicin encapsulation drug delivery system drug discovery drug repositioning drug repositioning approaches drug repurposing drug resistance drug-resistance mutations dual mode of action dual-target lead discovery epitope binning epitope mapping epitope prediction FimH fingerprints gene expression signature genome-wide genetic and epigenetic network (GWGEN) glycoprotein D (gD) haeckelite defects HDACs hERG toxicity herpes simplex virus fusion proteins high-throughput virtual screening HIV-2 protease homology modeling hTSPO human dihydrofolate reductase immunoproteasome in silico induced structural deformations induced-fit docking inhibitors isoform-selective histone deacetylase inhibitors isomeric space ligand-based model machine learning main protease MD binding MD simulation metadynamics methotrexate molecular docking molecular dynamics molecular dynamics (MD) simulation molecular dynamics simulation molecular dynamics simulations molecular modeling MRP4 multi-modal multiple-molecule drug multiprotein inhibiting natural compounds multiscale multitargeting mutants Mycobacterium tuberculosis n/a natural compounds neurodegenerative disorders nicotinic acetylcholine receptor non-covalent inhibitors noncovalent interactions oxidative stress PF-00835231 pharmacophore model pharmacophore modeling PK11195 polypharmacology proteasome protein docking protein threading modeling proteomic signature RNA expression regulation SARS-CoV-2 skin aging SNPs sodium-glucose co-transporters 2 Src inhibitors Stone-Wales defects structural bioinformatics structural characterization systems medicine design tuberculosis urinary tract infections uropathogenic bacteria variants virtual screening |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Computational Approaches |
| Record Nr. | UNINA-9910557519403321 |
|
Tutone Marco
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||