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In Silico Strategies for Prospective Drug Repositionings
| In Silico Strategies for Prospective Drug Repositionings |
| Autore | Udrescu Lucreția |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
COVID-19
drug repurposing topological data analysis persistent Betti function SARS-CoV-2 network-based pharmacology combination therapy nucleoside GS-441524 fluoxetine synergy antidepressant natural compounds QSAR molecular docking drug repositioning UK Biobank vaccine LC-2/ad cell line drug discovery docking MM-GBSA calculation molecular dynamics cytotoxicity assay GWAS multiple sclerosis oxidative stress repurposing ADME-Tox bioinformatics complex network analysis modularity clustering ATC code hidradenitis suppurativa acne inversa transcriptome proteome comorbid disorder biomarker signaling pathway druggable gene drug-repositioning MEK inhibitor MM/GBSA Glide docking MD simulation MM/PBSA single-cell RNA sequencing pulmonary fibrosis biological networks p38α MAPK allosteric inhibitors in silico screening computer-aided drug discovery network analysis psychiatric disorders medications psychiatry mental disorders toxoplasmosis Toxoplasma gondii in vitro screening drug targets drug-disease interaction target-disease interaction DPP4 inhibitors lipid rafts |
| ISBN | 3-0365-6133-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639987703321 |
Udrescu Lucreția
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Biocatalysis 2.0
| Molecular Biocatalysis 2.0 |
| Autore | Křen Vladimír |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (166 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
"solid-state biocatalysis"
2-ketoglutarate generation abiotic manganese oxides Agaricomycotina amine-reactive phenazine ethosulfate Aspergillus niger Basidiomycota biogenic manganese oxides cell wall anchor cyanide hydratase direct electron transfer E. coli enzyme cascade Fe(II)/2-ketoglutarate-dependent dioxygenase flavin FMO Glide docking glucose oxidase glucose sensor glycemic level monitoring glycosylation sites homology modeling hyaluronic acid hydroxy amino acids in vitro synthesis indigo Lactobacillus plantarum MISO library monooxygenase muramic acid n/a nitrilase nitrile non-reducing carbohydrate one-pot multi-enzyme optimization overproduction periplasm phylogenetic distribution Pseudomonas putida MnB1 quercetin recombinant horseradish peroxidase regio- and stereo-selective synthesis rutin rutinose rutinosidase sequential cascade reaction site-directed mutagenesis substrate docking substrate specificity surface display Talaromyces flavus transglycosylation whole-cell biocatalysis whole-cell biocatalyst α-Hydroxy-β-keto esters β-N-acetylhexosaminidases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557576703321 |
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Křen Vladimír
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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