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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (528 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
ABT-737
acetazolamide acetylcholine adjuvant therapy amoeboid motility angiogenesis apoptosis arthralgia Bcl-2 family BCL2L10 biomarkers BRAF BRAF inhibitor BRAF inhibitors BRAF-mutant melanoma cancer cancer associated fibroblast cancer stem cells carbonic anhydrase cell therapy checkpoint inhibitor cholinergic system combined therapy ctDNA CXCL10 cyclopamine cytokines cytotoxicity diagnosis DOCK4 drug resistance essential oils exosomes extracellular vesicles FAK hedgehog HIPPO HuR immunity immunotherapy interferon invasion ipilimumab lactate dehydrogenase lipid metabolism liquid biopsy liver-directed-therapies machine learning MANS peptide MARCKS mechanism of action melanoma melanoma immune infiltrate melanoma markers melanoma metastasis melanoma PDX melanomagenesis metalloproteinases metastases metastasis metastatic dormancy metastatic therapy metastatic uveal melanoma (mUM) microenvironment microRNAs MITF ML258 motility mucosal melanoma muscarinic receptors n/a nanoparticles nicotinic receptors nivolumab OXPHOS patient stratification PD-1 pembrolizumab phosphorylation plasmacytoid dendritic cells prediction principal component analysis prognosis prognostication protein tyrosine phosphatase PTPs inhibitors Rac1 radiotherapy resistance rheumatoid arthritis sex-hormones sex/gender ShcD adaptor protein siRNA slow cycling phenotype small molecules SOCE STAT3 Support Vector Machine survival target therapy targeted therapy targeted-therapy therapeutic resistance therapy TLR TPC2 tumor microenvironment tumour microenvironment uveal melanoma (UM) WNT5A |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological Activities of Alkaloids: From Toxicology to Pharmacology
| Biological Activities of Alkaloids: From Toxicology to Pharmacology |
| Autore | Adamski Zbigniew |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (270 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
?-carboline
acetylcholinesterase acid-sensing ion channel subtype 1a acute toxicity alkaloid alkaloids antibacterial anticancer antifungal antimicrobial activity antioxidant antiviral apoptosis Apoptosis Arecoline beetles berberine Berberis thunbergii biodistribution bisbenzylisoquinoline alkaloid chanoclavine Chelidonium majus Corydalis lutea Curine cytotoxic activity cytotoxicity dehydrocrenatidine di-ester diterpenoid alkaloids Dicentra spectabilis EGFR endophyte Epichloë ergot alkaloids FAK Fumaria officinalis glycoalkaloids HPLC-DAD inflammation insect insect heart isoquinoline alkaloids leukemia lindoldhamine lipopolysaccharide livestock lung cancer cells mAchR3 Macleaya cordata macrophage Mahonia aquifolia malonyl-solamargine malonylated form Meconopsis cambrica mono-ester diterpenoid alkaloids n/a natural products natural sources neuropathic pain neutrophil nociception Ovarian cancer Palmatine plant secondary metabolites Radix Aconiti Lateralis preparations reproduction Rutidea parviflora sanguinarine secondary metabolites short-term and long-term usage solamargine Solanum melongena L. solasonine SRC Staphylococcus aureus subchronic feeding study Tenebrio molitor toxicology voltage-gated sodium channels |
| ISBN | 3-03928-928-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Biological Activities of Alkaloids |
| Record Nr. | UNINA-9910404082303321 |
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Adamski Zbigniew
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (480 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
12-deacetyl-12-epi-scalaradial
3-alkylpyridinium polymers A375 and HeLa cell lines A549 cells ABC transporter actinomycin AD0157 adriamycin resistance Aeroplysinin Akt angiogenesis angiogenesis inhibitor ansamycins anthranilic acid anti-angiogenesis anti-angiogenic anti-cancer anti-metastatic activity anti-proliferation anti-proliferative antiangiogenesis antiangiogenic antibacterial Antibody Drug Conjugates (ADCs) anticancer anticancer activity anticancer agent anticancer immunity anticarcinogenic anticoagulant anticoagulation antifouling Antimicrobial peptide (AMP) antioxidant antiproliferative antiproliferative activity antitumor antitumor activities antitumoral antitumour AP-1 apoptosis apoptosis-inducing activity approved antitumor agents araguspongine C arrest of cell cycle Aspergillus autophagy autophagy inducers autophagy inhibitors azoxymethane BCRP/ABCG2 BEL-7402 cell benzo[a]pyrene bioactive natural product bioanalysis bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) bonnethead shark breast cancer breast cancer cells Brevianamide brominated indoles bromophenol buccal gland c-JUN c-Met C15 acetogenins camptothecin cancer Cancer cancer genes cancer preventive cancer progression Cantabrian Sea-derived actinobacteria carbocyclic analogue carcinoembryonic antigen Caribbean sponge carotenoid carotenoids caspase cascade cell adhesion cell adhesion molecules cell cycle cell cycle arrest cell migration cembranoids chemical conjugation chemoprevention chemopreventive chemosensitization chemotherapy chimera CHOP chromatography circulating tumor cells cisplatin clinical trials colorectal cancer cooperative binding cyclin D1 cyclin-dependent kinase CYP1A1 cystatin F cystatin superfamily cytokine release cytoskeleton cytotoxic activity cytotoxicity deep-sea depolymerisation dibromotyrosine dieckol divergolides DNA minor groove binder drug discovery Ecklonia cava elisidepsin EMT endoperoxide endophytic fungus endothelial cells energy stress epigonal organ epithelial-mesenchymal transition ER-stress ET-743 evolution FAK fascaplysin fatty acid 2-hydroxylase fatty acids FAU FBDD fucoidan fucoxanthin fumigaclavine C gemcitabine gene expression glioblastoma gliotoxin glucocorticoid receptor glycosaminoglycans gorgonian Haliclona gracilis HeLa cells heparan sulphate heparanase hepatocellular carcinoma HER2 HIF-1 hippuristanol HSP90 human lung cancer human normal diploid fibroblast (TIG-1 cells) human sarcoma cell line (HT1080 cells) humulane sesquiterpenoids hybridization hydroxylated lipids hypoxia hypoxia-inducible factor-1 IL-6 in vivo model inflammation inhibitor integrin β1 invasion isatin Isofistularin itampolin A jaspine B JNK1/2 Jurkat kalkitoxin kunitz type inhibitor Lampetra morii Leathesia nana Leptogorgia leukemia lipid rafts low molecular weight fucoidan extract low toxic LS-1 lung cancer lung metastasis Lyngbya majuscula macrolide mangrove-derived actinomycete manzamine A MAPK/ERK pathway marangucyclines marine antitumor agents marine biotechnology marine compound marine drug marine drugs marine fungus marine metabolites marine mollusc marine natural products marine organisms marine sponges marine-derived drugs Marthasterias glacialis L. MCP-1 mechanisms of action melanoma membrane permeabilization metastasis microalgae Micromonospora migration mitochondria mitochondria toxin mitochondrial pathway mitochondrial dysfunction molecular docking molecular mechanisms molecular modeling molecular oncology Moorea producens MRP1/ABCC1 multi-drug resistant leukemia multidrug resistance Mycalin A Mycochromenic acid derivative N-Ras n/a nanoparticle naphthopyrones natural marine compounds natural product natural products neuroblastoma-rat sarcoma NF-κB NF-κB signaling nicotine nicotinic acetylcholine receptor non-small cell lung cancer non-small cell lung cancer (NSCLC) non-small cell lung carcinoma nonfunctioning pituitary adenomas novel inhibitor NSCLC Nur77 osteosarcoma oxidative stress oxidative stress P-gp/ABCB1 P2X7 receptor p38 p38/ERK p38α p65 pachastrissamine palmitic acid paulomycins pazopanib PEL Penicillium brevicompactum Penicillium paneum phase I pheochromocytoma and paraganglioma phlorotannins phycocyanin PI3K/Akt plakortide plitidepsin pollution poly(ADP-ribose)-polymerase inhibitor polyoxygenated steroids polyphenols polysaccharides Porifera porifera/sponge preclinical programmed cell death programmed cell death-ligand 1 programmed cell death-ligand 2 proliferation prostate cancer proteasomal degradation proteomic pseudopterosin puupehenones pyrrolidinedione reactive oxygen species RGD motif ribosomal protein genes ROS RPS30 safety Sarcophyton ehrenbergi sea anemone sea cucumbers seaweed secondary metabolites sediment selenium-containing polysaccharide-protein complex Sepia ink polysaccharides shrimp signal transduction sinulariolide sipholenol A small cell lung cancer SNORA62 snoRNA SNU-C5/5-FU soft coral soft tissue sarcoma soft tissue sarcoma sphingosine kinase inhibitor sponge sponges STAT3 Streptomyces sp. SCSIO 11594 synergism synthetic analogues SZ-685C targeted therapy terpenes tetracenomycin X TGF-β signaling Thalassia testudinum thalassiolin B therapeutic compounds Tilapia piscidin 4 (TP4) TNFα Topo I inhibitor topoisomerase trabectedin triterpene glycosides TRPM7 tumor cell line tumor microenvironment tumor-associated macrophages Ulva fasciata uveal melanoma VEGF virtual screening xyloketal B α9-nicotinic acetylcholine receptors (nAChRs) αO-conotoxin GeXIVA β1-integrin λ-carrageenan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Universiteit Stellenbosch en die onverkwiklike taalstryd (2003-2017) : Vanaf "taaltameletjie" tot volskaalse "taaloorlog"
| Universiteit Stellenbosch en die onverkwiklike taalstryd (2003-2017) : Vanaf "taaltameletjie" tot volskaalse "taaloorlog" |
| Autore | Moll Johan C |
| Pubbl/distr/stampa | Bloemfontein, : UJ Press, 2018 |
| Descrizione fisica | 1 online resource (368 p.) |
| Soggetto topico |
Language teaching & learning (other than ELT)
linguistics |
| Soggetto non controllato |
Afrikaans
Afrikaanssprekende(s) aktivisties diversiteit dubbelmedium Engelssprekendes FAK geregtigheid Grondwet media meertaligheid moedertaalonderrig moedertaalsentiment Stellenbosch taalapartheid taalbeleid taalkwessies taalstryders transformasie verengelsing |
| ISBN | 1-928424-23-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | afr |
| Altri titoli varianti | Universiteit Stellenbosch en die onverkwiklike taalstryd |
| Record Nr. | UNINA-9910619478103321 |
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Moll Johan C
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| Bloemfontein, : UJ Press, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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