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Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor
| Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor |
| Autore | Holzmann Klaus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (276 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adenocarcinoma of the esophagogastric junction
AKT anticancer astrocytoma autocrine signaling autophagy brain cancer breast cancer cancer cancer signaling cancer-associated fibroblasts coreceptor ERK ERK1/2 estrogen FGF FGF-mediated signaling FGF18 FGF19 FGF2 FGF8 FGFR FGFR1 FGFR2 FGFR2c FGFR4 fibroblast growth factor fibroblast growth factor receptors FRS2 gastric cancer gene regulation GPER HCC HEK293 immunohistochemistry infigratinib sensitivity inhibitors JNK1 keratinocyte kinase inhibitor LY2874455 malignant glioma malignant pleural mesothelioma melanoma membrane proteins monoclonal antibody MTOR n/a negative feedback loop neoadjuvant therapy neurite outgrowth NVP-BGJ398 optogenetics overall survival PC12 phosphorylation prognosis receptor cross-talk receptor kinase resistance review sarcoma seborrheic keratosis serine signaling skin small molecule Sprouty proteins squamous and basal cell carcinoma structure targeted therapy tumor promoter tumor suppressor |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Fibroblast Growth Factor Receptor |
| Record Nr. | UNINA-9910557898903321 |
Holzmann Klaus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria in Health and Diseases
| Mitochondria in Health and Diseases |
| Autore | Javadov Sabzali |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (434 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
2-oxoglutarate dehydrogenase
4-HNE adenine nucleotide translocase ADP/ATP carrier aging amino acid neurotransmitter ancient mutation antioxidant system antioxidants apoptosis BAX BCL-2 BKCa channels cardiolipin cardiomyocytes cardioprotection cerebellar amino acid metabolism cholangiocellular carcinoma colon complex I (CI) deficiency cyclosporin A cytoskeletal proteins DDE dentate granule cell development dextran DRP1 dsRNA electron and confocal microscopy electron tunneling (ET) energy metabolism epilepsy ERK1/2 ETC complexes fatty acid oxidation ferritin gemfibrozil GW9662 H9c2 cardiomyoblasts healthy cells heart hepatic fibrogenesis hepcidin high-fat diet hippocampus HtrA2/Omi human amniotic membrane human diseases hyperforin hypoglycemia hypoxia inflammation innate immunity inorganic phosphate interferon response intranuclear mitochondria ion homeostasis iron overload ischemia reperfusion injury JNK KmADP Langendorff LHON life span lipid droplet lipid handling liver LONP1 metabolome and proteome profiling mitochondria mitochondria bioenergetics mitochondria calcium buffering mitochondria permeability transition pore mitochondria: energy metabolism mitochondrial cell death mitochondrial connexin 43 mitochondrial dynamics mitochondrial dysfunction mitochondrial function mitochondrial gene expression mitochondrial homeostasis mitochondrial interactions mitochondrial permeability transition pores mitochondrial UCP2 morphology mtDNA mtDNA transcription mtRNA muscle aging myocardial neuron death neuroprotection oxidative phosphorylation oxidative stress perilipin 5 physical performance pilocarpine pioglitazone PKA plectin post-transcriptional mtRNA processing potassium channel pravastatin protein phosphatases pyruvate dehydrogenase pyruvate dehydrogenase kinase reactive oxygen species reactive oxygen species (ROS) reactive oxygen species stress redox state regeneration respirasome assembly respiratory supercomplexes ROS rosiglitazone seizure Siberian population signaling signaling pathways siRNA sodium dichloroacetate specific genetic background telomerase activity telomere length tensile strength transferrin tricarboxylic acid cycle tubulin beta TUNEL TZD uncoupling uncoupling protein ZIP |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557577203321 |
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Javadov Sabzali
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitogen Activated Protein Kinases : Functions in Signal Transduction and Human Diseases
| Mitogen Activated Protein Kinases : Functions in Signal Transduction and Human Diseases |
| Autore | Tikkanen Ritva |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (276 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
angiogenesis
antimicrobial peptide aortic valve sclerosis aortic valve stenosis apoptosis atherosclerosis bone remodeling bronchopulmonary dysplasia cancer cancer signaling cecropin A cell cycle Compatibility CR cytokines DAPK DOK4 downregulation DUSP1 ERK ERK1/2 erlotinib extracellular signal-regulated kinase 5 (ERK5) extracellular signal-regulated kinases 1/2 FGF-induced signaling FR180204 FRS2 gastric ulcer HPAECs hyperoxia infantile myofibromatosis inflammation JNK JNKs Kv4.2 MAPK MAPK kinetics MAPK/PI3K/Akt signaling pathway MEK/ERK signaling metabolic profiling mitochondria mitochondrial dysfunction mitogen-activated protein kinase pathway (MAPK pathway) mitogen-activated protein kinases (MAPKs) MKK4 MKK7 N-heterocyclic carbene n/a naphthalimide-metal complex conjugates neuro-inflammation neurodegeneration NF-κB osteoclast differentiation oxidative stress p38 p38 MAPK p38 MAPKs p53 Parkinson's disease PC12 cells phosphorylation platelet-derived growth factor receptor porcine intestinal epithelial cell protein kinase inhibitors protein tyrosine phosphatase interacting protein 51 (PTPIP51) protein-protein interaction (PPI) psoriasis PTPN6 Rabdosia inflexa reactive oxygen species receptor tyrosine kinases ROS SIRT1 SIRT2 SR SRC sunitinib T2DM targeted therapy tight junction protein U0126 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Mitogen Activated Protein Kinases |
| Record Nr. | UNINA-9910557405603321 |
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Tikkanen Ritva
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting STAT3 and STAT5 in Cancer
| Targeting STAT3 and STAT5 in Cancer |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (578 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
ADAM17
adoptive T cell therapy AKT androgens apoptosis autoimmune disease autosomal-dominant hyper IgE syndrome Bone Marrow Failure Syndromes breast cancer cancer cancer models cancer progression cancer-stem cell CD38 CD4+ T cells CD8+ T cells cell cycle cell hierarchy chaperones chemotherapy resistance cirrhosis colon cancer companion animals comparative oncology cytokine cytokine receptor signaling dynamic programming endoplasmic reticulum (ER) stress epidermal growth factor receptor (EGF-R) ERK1/2 escape mechanisms gain-of-function mutation glioblastoma glioma growth hormone insensitivity syndrome heat shock proteins hedging hematopoietic cancers hepatitis C virus (HCV) hepatocellular carcinoma (HCC) hepatocyte nuclear factor 4 alpha (HNF4A) immune check point immune suppression immunosuppression immunotherapy inflammation inflammation associated cancer inflammatory hepatocellular adenomas interleukin-6 JAK JAK family of protein tyrosine kinases JAK2 V617F knockout lipopolyplex lung cancer lymphocytes lymphoma M2 macrophages melanoma meta-analysis metalloprotease metastasis microRNA-122 (miR-122) mitochondria MPN mTOR multiple myeloma mutations myeloid cells myeloid leukemia n/a nanoparticle neoplastic stem cells NGS NK cells nuclear factor erythroid 2-related factor 2 (NRF2) nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling ovarian cancer oxidative stress (OS) PD-L1 PEI pharmacological inhibitor pharmacological inhibitors polyethylenimine post-decision state variable prolactin proliferation prostate cancer RHOA risk management S3I-1757 SH2 domain shedding signal transducer and activator of transcription signal transducer and activator of transcription 3 (STAT3) siRNA delivery siRNA/RNAi small-molecule inhibitors solid cancers stabilization STAT STAT transcription factors STAT3 STAT3 inhibitor XIII STAT5 STAT5 signaling STAT5B signaling stem/progenitor cells stemness T-cell large granular lymphocytic leukemia T-cell leukemia T-cell prolymphocytic leukemia T-cells T-PLL targeted therapy targeting therapeutic targeting therapy resistance trans-signaling transaction costs tumor microenvironment tumor necrosis factor alpha (TNFα) tumor suppression tumor-associated macrophages tumor-immune cell interactions tumorigenesis tyrosine kinase 2 unfolded protein response (UPR) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557623503321 |
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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