DNA Damage, Oxidative Stress and Related Metabolic By-Products in Cancer and Environmental Studies
| DNA Damage, Oxidative Stress and Related Metabolic By-Products in Cancer and Environmental Studies |
| Autore | Peluso Marco E. M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (188 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
8-oxoguanine
abasic sites apoptosis autoimmunity base excision repair (BER) base excision repair (BER)glycosylases benzo[a]pyrene BPDE-DNA adduct cancer carcinogens chromatin organization chronic myeloid leukemia colorectal cancer comet assay detoxification Diamond-Blackfan anemia DNA damage DNA damage response DNA damage response and repair network DNA double-strand breaks DNA repair drug resistance environment pollution erythrocyte lifespan general anesthesia genetic instability hormesis immune response inflammatory cytokines M1dG metabolic adaptation metal biocontamination metallome metals n/a nasal epithelia neuraxial anesthesia Nrf2 nucleotide excision repair (NER) oxidative DNA damage oxidative stress PXR reactive oxygen species reactive oxygen species (ROS) rheumatoid arthritis silymarin systemic lupus erythematosus systemic sclerosis thyroid thyroid cancer VOCs volcano wood dust |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557898203321 |
Peluso Marco E. M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA Replication Stress / Robert M. Brosh
| DNA Replication Stress / Robert M. Brosh |
| Autore | Brosh Robert M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
Werner Syndrome
A549 cells epigenetic neurodegeneration Genome integrity adaptation cellular senescence genome instability Werner Syndrome Protein lipofuscin cell cycle checkpoints exonuclease 1 template-switching energy metabolism mutation frequency DNA replication fork regression motor neuron disease Microsatellites Alzheimer's disease chromatin remodeler repair of DNA damage AP site analogue mutagens replication timing Thermococcus eurythermalis nucleolar stress gene expression mutations spectra origin firing Fanconi Anemia superfamily 2 ATPase DNA translocation DNA repair SSB signaling homologous recombination common fragile sites 8-chloro-adenosine replication genome stability mutagenicity fork reversal multiple sclerosis non-B DNA protein stability heterogeneity ubiquitin SenTraGorTM (GL13) replication restart EdU ?-arrestin NER aging SSB end resection oxidative stress ATR dormant origins R loops DNA damage response Difficult-to-Replicate Sequences DNA double-strand repair endonuclease IV ALS double strand break repair premature aging replication stress EXO1 POL? translesion synthesis strand displacements G2-arrest DNA replication pattern SSB repair genome integrity G protein-coupled receptor kinase interacting protein 2 (GIT2) MMR replicative stress senolytics spacer interactome ATR-Chk1 DDR pathway C9orf72 replication fork restart translesion DNA synthesis DNA damage mismatch repair DNA replication stress DNA helicase Polymerase kappa DNA fiber assay H1299 cells TLS APE2 ageing cell death chromosome TopBP1 barley clock proteins post-translational modification 8-oxoG S phase ataxia telangiectasia mutated (ATM) G protein-coupled receptor (GPCR) Polymerase eta cancer G protein-coupled receptor kinase (GRK) helicase genomic instability Parkinson's disease nucleotide excision repair SupF |
| ISBN |
9783039213900
3039213903 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367564903321 |
Brosh Robert M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging Role of Lipids in Metabolism and Disease
| Emerging Role of Lipids in Metabolism and Disease |
| Autore | Pallottini Valentina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (308 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acid sphingomyelinase
adiponectin adipose tissue angiogenesis atherosclerosis ATM autotaxin BDNF BET proteins brain breast cancer breast reconstruction cardiovascular disease cell proliferation cell signaling cholesterol Cholesterol chronic inflammation diabetes mellitus DNA damage response double strand breaks eicosanoids endothelial cell epicardial fat thickness epigenetics epinephrine fatty acid Fatty acids female frontal cortex G-protein coupled receptors gender glyceride haptoglobin high-cholesterol diet high-density lipoprotein high-sensitivity c-reactive protein hippocampus HMGCR hyperglycemia ionizing radiation ischemia ischemic stroke JQ1 LDLr leptin lipid lipid droplets lipid mediators Lipid mediators lipid metabolism lipid metabolism diseases lipid storage diseases Lipids lipocalin lipolysis lipophagy Lipophagy lipoproteins liver lysocardiolipin acyltransferase lysophosphatidic acid metabolic reprogramming metabolic stress metabolism mTORC1 mutations neutral sphingomyelinase nuclear sphingolipids oral drug absorption oxidative stress oxidized phospholipids p53 pathology phosphatidylinositol 4,5-bisphosphate phospholipase A2 (PLA2) phospholipase C phospholipase D phospholipid polyunsaturated fatty acids prodrug prostaglandins pulmonary fibrosis radiation SOD sphingolipids Sphingolipids sphingomyelin metabolism sphingosine kinase 1 sphingosine-1-phosphate SREBP steroid synaptic proteins TFEB TMEM97 visceral fat thickness |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557800303321 |
Pallottini Valentina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Lo trovi qui: Univ. Federico II | ||
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Grappling with the Multifaceted World of the DNA Damage Response
| Grappling with the Multifaceted World of the DNA Damage Response |
| Autore | Antonio Porro |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 online resource (306 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Genetics (non-medical) |
| Soggetto non controllato |
DNA Damage
DNA damage response DNA Repair genome instability Genome integrity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910220034503321 |
Antonio Porro
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| Frontiers Media SA, 2017 | ||
| Lo trovi qui: Univ. Federico II | ||
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Malignant Mesothelioma
| Malignant Mesothelioma |
| Autore | L. Pouliquen Daniel |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (328 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
asbestos
asbestos exposure BAP1 biomarkers cancer biomarkers cancer-specific mutations cancers carbon nanotubes carcinogenesis CDKN2A circulating tumor DNA dendritic cells DNA damage response DNA methylation DNA sequencing drug repurposing epigenome-wide analysis epithelioid extrapleural pneumonectomy fatty acid-binding protein FDG first line gene expression genomics Hippo pathway histotype immune therapy immunogenicity immunohistochemistry immunotherapy infiltrating immune cells inflammation interaction analysis laminin subunit beta-2 liquid biopsies lurbinectedin lymphocyte-to-monocyte ratio macrophage-capping protein malignant mesothelioma malignant pleural mesothelioma mesothelioma mesothelium meta-analysis metabolomics MPM MTAP mutation n/a network analysis NF2 oxidative stress PET-CT plasma pleural effusion pleural mesothelioma pleurectomy decortication predictive biomarker prognostic biomarker protein-protein interactions proteomics PTCH1 radiotherapy redox-sensitive factors sarcomatoid selenium-binding protein 1 SETD2 survival survival analysis systematic review systems biology targeted therapy therapy response tumor microenvironment tumor suppressor tumor-associated macrophages VATS WDPM well-differentiated papillary mesothelioma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557359303321 |
L. Pouliquen Daniel
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Lo trovi qui: Univ. Federico II | ||
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Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer
| Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer |
| Autore | Nakayama Naomi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (258 p.) |
| Soggetto topico | Public health and preventive medicine |
| Soggetto non controllato |
adoptive immunotherapy
anti-angiogenic therapy aryl hydrocarbon receptor BEN (BANP, E5R and NAC1) domain biological planning biomarkers borderline ovarian tumors BRCA1 mutant ovarian cancer cancer progression CD44 cervical cancer cervical neoplasia chimeric antigen receptor clear cell carcinoma differentially expressed genes DNA damage response DNA mismatch repair (MMR) drug repurposing endometrial cancer endometrial carcinoma endometrioid endometrial cancer epithelial ovarian cancer epithelial ovarian cancers epithelial-mesenchymal transition exosome gene ontology gynecological cancer HDR brachytherapy human cytomegalovirus immune checkpoints inhibitors immune micro-environment immunohistochemistry immunosuppression in vivo dosimetry inflammation integrative analysis interventional radiotherapy isothermal titration calorimetry (ITC) liquid biopsy long-term survival melanoma treatment microsatellite instability miRNA mismatch repair deficiency MMR deficient (dMMR) n/a nanocarriers NK cells non-coding RNAs nucleus accumbens-associated protein 1 (NAC1) ovarian cancer p16 protein pGSK3β PLA2G7) platelet-activating factor acetylhydrolase (PAF-AH prognosis sequence-specific DNA-binding protein solution NMR structure somatic mutation targeted therapy testin vaginal melanoma vaginal-cuff brachytherapy vulvar melanoma Wnt signaling β-catenin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580209103321 |
Nakayama Naomi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Lo trovi qui: Univ. Federico II | ||
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Ubiquitin and Ubiquitin-Relative SUMO in DNA Damage Response
| Ubiquitin and Ubiquitin-Relative SUMO in DNA Damage Response |
| Autore | Kristijan Ramadan |
| Pubbl/distr/stampa | Frontiers Media SA, 2018 |
| Descrizione fisica | 1 online resource (183 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Genetics (non-medical) |
| Soggetto non controllato |
Cancer
DNA damage response genome stability SUMO Sumoylation Ubiquitin Ubiquitination |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346749903321 |
Kristijan Ramadan
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| Frontiers Media SA, 2018 | ||
| Lo trovi qui: Univ. Federico II | ||
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