Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Drug-Drug Interactions
| Drug-Drug Interactions |
| Autore | Kim Dong Hyun |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (242 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
(‒)-sophoranone
1A2 2B6 2C19 2C8 2C9 2D6 3A4 ADME adverse drug reactions biflavonoid chronic kidney disease competitive inhibition computational prediction CYP CYP1A1 CYP1A2 CYP2C9 CYP2D6 CYP3A CYP3A4 cytochrome P450 cytochromes P450 DDI Dexamethasone drug interaction drug interactions drug metabolism drug transporter drug-drug interaction drug-drug interactions expression fexofenadine gepants high plasma protein binding in silico in vitro in vivo inhibitor ixazomib Ketoconazole lasmiditan Lexicomp low permeability Loxoprofen mechanism-based inhibition metabolic DDI metabolism migraine monoclonal antibodies non-competitive inhibition O-desmethyltramadol OATP1B1 OATP1B3 organic anion transporting polypeptide 1A2 (OATP1A2) P-glycoprotein (P-gp) P450 pharmacokinetics physiologically-based pharmacokinetics plasma concentration polypharmacy potent inhibition QSAR regulation Rumex acetosa selamariscina A signal detection algorithms spontaneous reporting systems subset analysis substrate systemic exposure tadalafil ticagrelor tissue-specific tramadol tyrosine kinase inhibitors ubiquitination uridine 5'-diphosphoglucuronosyl transferase |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557666403321 |
Kim Dong Hyun
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation
| Regional Intestinal Drug Absorption : Biopharmaceutics and Drug Formulation |
| Autore | Gonzalez-Alvarez Maria Isabel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (238 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
absorption-modifying excipients
BCS class IV drugs BCS drugs bioequivalence biomimetic membrane biopharmaceutics biopharmaceutics classification system Biopharmaceutics Classification System clinical studies colon absorption combined zero- and first-order absorption controlled release drug product DDI disintegration dissolution dissolution test drug absorption drug permeability drug solubility drug solubility/dissolution drug-drug interactions energy intake enteric-coated first-order absorption first-pass effect Franz cell Franz-PAMPA furosemide gastrointestinal gastrointestinal hormone GastroPlus hierarchical support vector regression (HSVR) human colon carcinoma cell layer (Caco-2) ibuprofen ICH in silico modeling in situ perfusion in vitro in vitro in vivo extrapolations intestinal absorption intestinal perfusion intestinal permeability IVIVE location-dependent absorption manometry mechanistic modeling microdevices mucoadhesion nutrient absorption nutrient digestion obesity oral absorption oral drug delivery oral peptide delivery passive drug transport PBBM PBPK permeation enhancers pharmaceutical development pharmacokinetics Phoenix WinNonlin physiologically-based pharmacokinetic (PBPK) modeling postprandial glycaemia pravastatin quality control region of the gut regional intestinal permeability regional/segmental-dependent permeability and absorption route-dependent intestinal metabolism segmental-dependent intestinal permeability segregated flow intestinal model (SFM) shape traditional model (TM) transit compartment absorption model type 2 diabetes zero-order absorption |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Regional Intestinal Drug Absorption |
| Record Nr. | UNINA-9910566462603321 |
|
Gonzalez-Alvarez Maria Isabel
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||