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Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0
Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0
Autore Dansette Patrick M
Pubbl/distr/stampa Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Descrizione fisica 1 electronic resource (286 p.)
Soggetto topico Research & information: general
Soggetto non controllato Antibiotics
Bacillus
biosynthetic gene clusters
comparative analysis
cytochrome P450 monooxygenase
Mycobacterium
P450 diversity percentage
P450 profiling
secondary metabolites
NADPH-cytochrome P450 reductase (CPR)
microsomal cytochrome P450 (CYP)
Cytochrome b5 (CYB5)
protein dynamics
electron-transfer (ET)
protein–protein interaction
cytochromes P450
CYP3A4
active site access channels
cavities boundaries
minimal cost paths
CYP139A1
genome data mining
host metabolism
Mycobacterium tuberculosis
polyketides
tuberculosis
cryptococcus
cryptococcus neoformans
CYP51
fungal pathogens
genome data-mining
human pathogens
CYP diversity analysis
tremellomycetes
trichosporon
mechanism-based inhibitor
crystal structure
CYP4 genes
genetic polymorphisms
20-HETE
fatty acid
arachidonic acid
SNPs
molecular functionality
metabolism
lamellar ichthyosis
Bietti’s crystalline dystrophy
cytochrome P450
isoform
membrane protein
protein-membrane interactions
enzyme substrate specificity
mutagenesis
molecular dynamics simulation
Sogatella furcifera
sulfoxaflor
transcriptome
RNA interference
CYP2C8
polymorphisms
reactive oxygen species
paclitaxel
cytochrome P450 reductase
electron transfer
extracellular vesicles
exosomes
extrahepatic tissues
plasma
circulatory CYPs
CYP450
drug metabolism
precision Cardio-Oncology
precision medicine
systems medicine
cytochromes P450 monooxygenases
Cyanobacteria
gene-cluster diversity percentage
mathematical formula
phylogenetic analysis
Streptomyces
cytochrome P450 monooxygenases
terpenes
P450 blooming
non-ribosomal peptides
cytochrome P450 monooxygenenases
CYP128A1
Mycobacterium tuberculosis H37Rv
molecular dynamic simulations
azole drugs
menaquinone
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Cytochromes P450
Record Nr. UNINA-9910557761103321
Dansette Patrick M  
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Drug Metabolism/Transport and Pharmacokinetics
Drug Metabolism/Transport and Pharmacokinetics
Autore Song Im-Sook
Pubbl/distr/stampa Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Descrizione fisica 1 electronic resource (232 p.)
Soggetto topico Medicine
Pharmaceutical industries
Soggetto non controllato tofacitinib
dose-dependent pharmacokinetics
hepatic and intestinal first-pass effect
rats
catalposide
in vitro human metabolism
UDP-glucuronosyltransferase
sulfotransferase
carboxylesterase
celecoxib
drug–drug interaction
fluorescence
HPLC
metabolism
repaglinide
HSG4112
anti-obesity agent
stereoselectivity
pharmacokinetics
compound K
protopanaxadiol (PPD)
biliary excretion
intestinal metabolism
Carthamus tinctorius extract
notoginseng total saponins
comparative pharmacokinetic study
large volume direct injection
compatibility mechanism
mertansine
human hepatocytes
cytochrome P450
UDP-glucuronosyltransferases
sodium-glucose cotransporter 2 (SGLT2) inhibitors
DWP16001
kidney distribution
inhibition mode
diabetes
transporter-enzyme interplay
influx transporter
efflux transporter
physiologically based pharmacokinetic model
cytochrome P450 enzymes
tiropramide
healthy Korean subjects
modeling
population pharmacokinetic
quercetin
breast cancer resistance protein
inhibitor
prazosin
sulfasalazine
kinetic analysis
food–drug interactions
Caco-2
EpiIntestinal
first-pass
P-gp
BCRP
drug transporter
CYP3A4
oral availability
automatization
drug absorption
drug dosing
head-and-neck cancer
real-time measurements
taxanes
tissue engineering
UHPLC-MS/MS
metformin
verapamil
drug interaction
organic cation transporter 2
renal excretion
acute renal failure
gentamicin
cisplatin
hepatic CYP3A1(23)
creatinine clearance
renal clearance
nonrenal clearance
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910557607703321
Song Im-Sook  
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Drug-Drug Interactions
Drug-Drug Interactions
Autore Kim Dong Hyun
Pubbl/distr/stampa Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Descrizione fisica 1 electronic resource (242 p.)
Soggetto topico Research & information: general
Biology, life sciences
Soggetto non controllato tadalafil
ticagrelor
drug-drug interaction
pharmacokinetics
plasma concentration
CYP3A4
Loxoprofen
CYP3A
Dexamethasone
Ketoconazole
CYP2D6
O-desmethyltramadol
physiologically-based pharmacokinetics
tramadol
(‒)-sophoranone
CYP2C9
potent inhibition
in vitro
in vivo
drug interaction
low permeability
high plasma protein binding
biflavonoid
cytochrome P450
drug interactions
selamariscina A
uridine 5′-diphosphoglucuronosyl transferase
tissue-specific
systemic exposure
P-glycoprotein (P-gp)
organic anion transporting polypeptide 1A2 (OATP1A2)
Rumex acetosa
fexofenadine
chronic kidney disease
drug–drug interactions
polypharmacy
adverse drug reactions
Lexicomp
subset analysis
signal detection algorithms
spontaneous reporting systems
mechanism-based inhibition
competitive inhibition
non-competitive inhibition
substrate
inhibitor
cytochromes P450
OATP1B1
OATP1B3
tyrosine kinase inhibitors
drug-drug interactions
migraine
lasmiditan
gepants
monoclonal antibodies
CYP1A1
CYP1A2
drug–drug interaction
expression
metabolism
regulation
drug transporter
ubiquitination
ixazomib
DDI
computational prediction
in silico
QSAR
drug metabolism
ADME
CYP
metabolic DDI
P450
1A2
2B6
2C19
2C8
2C9
2D6
3A4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910557666403321
Kim Dong Hyun  
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui