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Computational Methods for the Analysis of Genomic Data and Biological Processes
| Computational Methods for the Analysis of Genomic Data and Biological Processes |
| Autore | Gómez Vela Francisco A |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
HIGD2A
cancer DNA methylation mRNA expression miRNA quercetin hypoxia eQTL CRISPR-Cas9 single-cell clone fine-mapping power RNA N6-methyladenosine site yeast genome methylation computational biology deep learning bioinformatics hepatocellular carcinoma transcriptomics proteomics bioinformatics analysis differentiation Gene Ontology Reactome Pathways gene-set enrichment meta-analysis transcription factor binding sites genomics chilling stress CBF DREB CAMTA1 pathway text mining infiltration tactics optimization algorithm classification clustering microarray ensembles machine learning infiltration computational intelligence gene co-expression network murine coronavirus viral infection immune response data mining systems biology obesity differential genes expression exercise high-fat diet pathways potential therapeutic targets DNA N6-methyladenine Chou's 5-steps rule Convolution Neural Network (CNN) Long Short-Term Memory (LSTM) machine-learning chromatin interactions prediction genome architecture |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557129603321 |
Gómez Vela Francisco A
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Muscle Homeostasis and Regeneration : From Molecular Mechanisms to Therapeutic Opportunities
| Muscle Homeostasis and Regeneration : From Molecular Mechanisms to Therapeutic Opportunities |
| Autore | Musarò Antonio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (500 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
lysine
mTORC1 satellite cells proliferation skeletal muscle growth muscle satellite cell transthyretin thyroid hormone myogenesis exosomes skeletal muscle genotype genetic variation muscle phenotypes sarcopenia aging calcium homeostasis hibernation mitochondria sarcoplasmic reticulum Acvr1b Tgfbr1 myostatin Col1a1 fibrosis atrophy IGF2R muscle homeostasis inflammation muscular dystrophy pericytes macrophages Nfix phagocytosis RhoA-ROCK1 splicing isoforms CRISPR-Cas9 exon deletion NF-Y muscle differentiation C2C12 cells denervation neuromuscular junction heavy resistance exercise acetylcholine receptor cell culture neonatal myosin neural cell adhesion molecule biomarkers mitophagy mitochondrial dynamics mitochondrial quality control mitochondrial-derived vesicles (MDVs) mitochondrial-lysosomal axis Hibernation electron microscopy immunocytochemistry α-smooth muscle actin confocal microscopy connexin 43 connexin 26 gap junctions myofibroblasts Platelet-Rich Plasma transforming growth factor (TGF)-β1 muscle regeneration inflammatory response cell precursors experimental methods stem cell markers muscles heterotopic ossification skeletal muscle stem and progenitor cells HO precursors muscle atrophy septicemia mitochondrial fusion mitochondrial fission iPSC extracellular vesicles Drosophila muscle genetic control muscle diversification fascicle myofiber myofibril sarcomere hypertrophy hyperplasia splitting radial growth longitudinal growth exercise muscle stem cells stem cells niche neuromuscular disorders Duchenne muscular dystrophy pharmacological approach single-cell mass cytometry skeletal muscle regeneration skeletal muscle homeostasis fibro/adipogenic progenitors myogenic progenitors muscle populations evolution metazoans differentiation transdifferentiation muscle precursors regenerative medicine stem cells FAPs tissue niche growth factors muscle pathology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Muscle Homeostasis and Regeneration |
| Record Nr. | UNINA-9910557587003321 |
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Musarò Antonio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Understanding Neuromuscular Health and Disease: Advances in Genetics, Omics, and Molecular Function
| Understanding Neuromuscular Health and Disease: Advances in Genetics, Omics, and Molecular Function |
| Autore | Duddy William |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
LMNA
Emery-Dreifuss muscular dystrophy Omics ALS MND ALS variants genotype-phenotype ALS genes FSHD DUX4 transcription muscle regulation spinal muscular atrophy adult patients disease heterogeneity Nusinersen disease modifiers functional outcomes biomarkers epigenetic changes -omics approaches oxidative stress mitochondria dysfunction axonal transport autophagy endocytosis secretion excitotoxicity RNA metabolism Duchenne muscular dystrophy (DMD) exon-skipping therapies next-generation sequencing (NGS) Sanger sequencing multiplex ligation probe amplification (MLPA) multiplex polymerase chain reaction (PCR) comparative genomic hybridization array (CGH) viltolarsen eteplirsen golodirsen rheumatoid arthritis SNP DMARD methotrexate pharmacogenomics Duchenne muscular dystrophy pharmacodynamic biomarkers prednisone deflazacort glucocorticoids corticosteroids safety neuromuscular diseases translational research disease models precision medicine miRNA proteomics calprotectin dystrophy Becker muscular dystrophy dystrophinopathy genotype-phenotype correlations Canadian Neuromuscular Disease Registry reading frame rule dystrophin multiple logistic regression analysis exon skipping therapy Amyotrophic Lateral Sclerosis machine learning genome-wide association studies GWAS genomics ALS pathology gene prioritization AAV genetic neuromuscular disorders gene therapy clinical trials toxicity SMA DMD XLMTM facioscapulohumeral dystrophy TALEN CRISPR-Cas9 gene editing polyadenylation D4Z4 duchenne muscular dystrophy (DMD) becker muscular dystrophy (BMD) exon skipping skip-equivalent deletions |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Understanding Neuromuscular Health and Disease |
| Record Nr. | UNINA-9910557669103321 |
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Duddy William
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Yeast Biotechnology 3.0
| Yeast Biotechnology 3.0 |
| Autore | Willaert Ronnie G |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (240 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
coffee processing
coffee fermentation starter culture coffee beverage yeast Icewine Saccharomyces cerevisiae hyperosmotic stress CRISPR-Cas9 glycerol transport STL1 brewing Cyberlindnera NABLAB non-alcoholic beer non-conventional yeast non-Saccharomyces yeast response surface methodology Ustilago itaconic acid process improvement lignocellulosic feedstock yeasts grape federweisser wine microbiota identification MALDI-TOF MS Biotyper Torulaspora delbrueckii craft beer microbrewery plant mixed fermentation aroma profile strain collection aroma profiling gas chromatography wine yeast Saccharomyces fermentation volatile aroma compounds Simultaneous inoculation Alcoholic fermentation Malolactic fermentation Sacccharomyces cerevisiae Oenococcus oeni PN4TM OmegaTM Aroma profile antioxidant coffee W. anomalus industrial brewer’s strains adaptive laboratory evolution (ALE) snowflake phenotype beer fermentation wine yeasts lactic acid bacteria co-inoculation sequence inoculation flavor compounds color pigments cell printing piezoelectric dispensing GFP-tagged yeast clone collection living cell microarrays microfluidic chip dynamic single-cell analysis Candida albicans adhesion fibronectin nanomotion atomic force microscope (AFM) xylose metabolism genetic engineering biofuel Spathaspora passalidarum Pichia stipitis volatile organic compounds proton-transfer reaction-mass spectrometry Metschnikowia pulcherrima flavor non-Saccharomyces yeasts fermentation-derived products fermented beverages beer coffee bean fermentation itaconic acid production bioethanol production bioreactors yeast micro- and nanobiotechnology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557545103321 |
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Willaert Ronnie G
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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