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Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan
| Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan |
| Autore | Puca Annibale |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
aging
alternative therapy composition of royal jelly dietary interventions healthspan lifespan longevity royal jelly IGF-1 oxidative stress ageing nematode immunosenescence probiotic bacteria pathogen protection food allergy elderly hypersensitivity gut allergy inflammation redoxomics glutathione meniere's disease neurodegenerative diseases healthy aging DNA methylation epigenetic clocks telomere length centenarians exosomes serum functional enrichment analysis ingenuity pathway analysis miRNA-mRNA networks aging-related disease Di (2-Ethylhexyl) pthalate Hericium erinaceus vitagenes apoptosis mitochondrial respiratory complexes C. elegans polyphenols olive oil Parkinson's disease β-Dystroglycan cellular senescence lamin B1 DNA-damage response defective mitosis |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557783503321 |
Puca Annibale
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metabolomics in Neurodegenerative Disease
| Metabolomics in Neurodegenerative Disease |
| Autore | Green Brian |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto non controllato |
glutamic acid
direct mass spectrometry neurodegeneration 6-OHDA targeted mass spectrometry mitochondrial dysfunction myo-inositol metabolomics bile acids subacute mild traumatic brain injury age-related macular degeneration metabolic pathways energy metabolism midbrain Alzheimer's disease biomarkers 1H NMR Parkinson's disease dementia GC-MS pathogenesis tricarboxylic acid cycle micro-dialysis 13C-labeled succinate metabolism lipidomics dementia with Lewy bodies fatty acid prodromal Parkinson's disease malonate cerebral ischemia mass spectrometry retinal pigment epithelium excitotoxicity endothelin-1 reperfusion C. elegans Streptomyces venezuelae ?-synuclein aggregates natural product fatty acid metabolism imaging mass spectrometry LC-MS drusen cerebral palsy plasma Parkinson's disease |
| ISBN | 3-03928-041-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087203321 |
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Green Brian
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nanobody
| Nanobody |
| Autore | Rothbauer Ulrich |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Bacillus anthracis
immunoassay single-domain antibody genetic fusion Beta galactosidase P-type ATPase nanobody llama Zinc-transport Zinc-transporting P-ATPase ZntA TNF fluorescent nanobodies sensor anti-cytokine therapy autoimmune disease Western equine encephalitis virus MagPlex toxin antibody camelid vaccine biodefense hydrogen exchange-mass spectrometry virus formatting Fc-domain half-life ischemia stroke MCAO single domain antibodies phage display intrabody intracellular antibody GTPase RHO BRET RAS chromobodies live-cell imaging compound screening cellular models single-domain antibody fragments molecular imaging molecular therapy nuclear imaging targeted fluorescence imaging intraoperative imaging Nanobody Single Domain Antibody Cancer Immunotherapy Imaging influenza influenza B virus hemagglutinin single domain antibody NanobodyTM yeast display epitope mapping GFP C. elegans development drosophila zebrafish targeted photodynamic therapy hepatocyte growth factor receptor HGFR c-Met Met VHH photosensitizer single-domain antibodies neurodegenerative diseases brain imaging blood-brain barrier delivery Aids HIV Llama Antibodies bi-specific VHH pepscan competition studies co-crystallisation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557147503321 |
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Rothbauer Ulrich
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Products and Neuroprotection
| Natural Products and Neuroprotection |
| Autore | Angeloni Cristina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (338 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Vitamin D
Multiple Sclerosis symptom neurodegeneration oxidative injury Parkinson's disease terpenes, rotenone thymol Alzheimer's disease Centella asiatica hippocampus protein poshophatase 2 glycogen synthase kinase 3 B-cell lymphoma 2 neuroprotection nutraceuticals bioavailability stress response neurodegenerative disease bioactive compound natural extract β-amyloid peptide tau protein clinical trial human studies animal studies in vitro studies curcumin free radicals heme oxygenase safety profile type 2 diabetes inflammation vascular damage learning memory natural compound oxidative stress cognitive dysfunction cell death synapse loss protein aggregation neuroinflammation algae seaweeds neurodegenerative diseases auraptene dopamine neuron antioxidant mitochondria Chionanthus retusus flavonoid flower HO-1 NO Lippia citriodora VEE Vs relaxation depression cyclic AMP calcium blood-brain barrier catechin cognition epigallocatechin gallate green tea microbiota 5-(3,5-dihydroxyphenyl)-γ-valerolactone ascaroside pheromone C. elegans dauer neuronal signaling sexual behavior survival signals proteostasis chaperones autophagy ubiquitin-proteasome unfolded protein response natural compounds natural products ethics patients' autonomy beneficence nonmaleficence medical liability Parkinson's disease (PD) mitochondrial dysfunction dynamics hormesis ubiquitin‒proteasome system (UPS) mitophagy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557705603321 |
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Angeloni Cristina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neural circuits : Japan / / topic editor: Yasuo Kawaguchi and Masanobu Kano
| Neural circuits : Japan / / topic editor: Yasuo Kawaguchi and Masanobu Kano |
| Autore | Masanobu Kano |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 online resource (220 pages) : illustrations; digital file(s) |
| Collana | Frontiers Research Topics |
| Soggetto topico |
Neuroscience
Human Anatomy & Physiology Health & Biological Sciences |
| Soggetto non controllato |
Cerebellum
C. elegans Drosophila Olfactory Bulb Basal Ganglia Hypothalamus Neocortex Hippocampus |
| ISBN | 9782889194377 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137536803321 |
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Masanobu Kano
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Glia in Plasticity and Behavior
| The Role of Glia in Plasticity and Behavior |
| Autore | Tycho Hoogland |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 electronic resource (104 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Cerebellum
C. elegans Astrocytes DREADD Cortex plasticity Gq Behavior glia Hippocampus |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910136803103321 |
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Tycho Hoogland
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ubiquitin and Autophagy
| Ubiquitin and Autophagy |
| Autore | Nazarko Taras Y |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (294 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
PSMD14
ubiquitin retrograde trafficking APP autophagy Cx43 GABARAP gap junction MAPLC3 leukodystrophies globoid cell leukodystrophy psychosine p62 proteasome toll-like receptor 4 TRAF6 BECN1 ATG12~5/16 complex Dictyostelium ubiquitin-like protein phagocytosis pinocytosis UPS ubiquitin-proteasome system crosstalk tissue specificity C. elegans NFAT5 autophagy initiation islet FIP200 unfolded protein response UPR Atg8 LC3 LIR motif SAR UBL neurodegenerative diseases autophagy-lysosome pathway lysosome selective autophagy ubiquitination degradation the ubiquitin-proteasome system plants mitophagy aggrephagy lysophagy xenophagy lipophagy nucleophagy ER-phagy cargo receptors sorting nexins retromer endosome |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339503321 |
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Nazarko Taras Y
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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