Info
Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (528 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
ABT-737
acetazolamide acetylcholine adjuvant therapy amoeboid motility angiogenesis apoptosis arthralgia Bcl-2 family BCL2L10 biomarkers BRAF BRAF inhibitor BRAF inhibitors BRAF-mutant melanoma cancer cancer associated fibroblast cancer stem cells carbonic anhydrase cell therapy checkpoint inhibitor cholinergic system combined therapy ctDNA CXCL10 cyclopamine cytokines cytotoxicity diagnosis DOCK4 drug resistance essential oils exosomes extracellular vesicles FAK hedgehog HIPPO HuR immunity immunotherapy interferon invasion ipilimumab lactate dehydrogenase lipid metabolism liquid biopsy liver-directed-therapies machine learning MANS peptide MARCKS mechanism of action melanoma melanoma immune infiltrate melanoma markers melanoma metastasis melanoma PDX melanomagenesis metalloproteinases metastases metastasis metastatic dormancy metastatic therapy metastatic uveal melanoma (mUM) microenvironment microRNAs MITF ML258 motility mucosal melanoma muscarinic receptors n/a nanoparticles nicotinic receptors nivolumab OXPHOS patient stratification PD-1 pembrolizumab phosphorylation plasmacytoid dendritic cells prediction principal component analysis prognosis prognostication protein tyrosine phosphatase PTPs inhibitors Rac1 radiotherapy resistance rheumatoid arthritis sex-hormones sex/gender ShcD adaptor protein siRNA slow cycling phenotype small molecules SOCE STAT3 Support Vector Machine survival target therapy targeted therapy targeted-therapy therapeutic resistance therapy TLR TPC2 tumor microenvironment tumour microenvironment uveal melanoma (UM) WNT5A |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Impaired Mitochondrial Bioenergetics under Pathological Conditions
| Impaired Mitochondrial Bioenergetics under Pathological Conditions |
| Autore | Lenaz Giorgio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (460 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research & information: general |
| Soggetto non controllato |
aging
aging heart assembly factor ATP synthase ATP synthase/hydrolase atypical myopathy Barth syndrome Bcl-2 family bioenergetics C cancer cardiolipin cardiomyopathy cell culture cell signaling cellular bioenergetics cellular signaling complex I assembly complex I deficiency complex I structure complex III COVID-19 cristae cytochrome b diabetes Dilated Cardiomyopathy with Ataxia electron transport chain energy metabolism entorhinal cortex equine primary myoblasts exercise fatty acid oxidation fibroblasts frozen tissue G mutation glucagon heart failure high-resolution respirometry human disease immune system influenza innate immune response insulin Leigh syndrome leukocytes lipoxidation-derived damage m.3243A> m.8909T> mammalian complex I mathematical model MAVS MDA5 metabolic disease mitochondria mitochondrial disease mitochondrial diseases mitochondrial DNA mitochondrial dynamic mitochondrial dynamics mitochondrial dysfunction mitochondrial permeability transition pore mitochondrial proteostasis MT-ATP6 MTCYB mutations n/a NADH dehydrogenase nephropathy neurodegeneration oleate oxidative damage oxidative phosphorylation oxidative stress oxygen consumption palmitate pancreatic endocrine cells pet mutants platelets programmed cell death protein import respiratory chain respiratory complex assembly respiratory complexes respiratory supercomplexes respirometry RIG-I ROS RSV Saccharomyces cerevisiae SARS CoV-2 Sengers syndrome skeletal muscle supercomplexes supernumerary subunits toxicity assays viral infections yeast |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585934503321 |
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Lenaz Giorgio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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