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Radiolabelled Molecules for Brain Imaging with PET and SPECT
| Radiolabelled Molecules for Brain Imaging with PET and SPECT |
| Autore | Brust Peter |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (244 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
SV2A
SV2B SV2C microPET [18F]UCB-H epilepsy PBIF distribution volume blocking assay preclinical imaging Alzheimer’s disease (AD) network measure graph theory brain network positron emission tomography (PET) persistent homology Phosphodiesterase 2A (PDE2A) Positron Emission Tomography (PET) Benzoimidazotriazine (BIT) fluorinated Mouse Liver Microsomes (MLM) cyclic nucleotide phosphodiesterase PDE2A radioligand nitro-precursor fluorine-18 in vitro autoradiography PET imaging opioid receptors positron emission tomography radiotracers μOR-, δOR-, κOR- and ORL1-ligands movement disorders pain drug dependence GBM biomarkers Sigma 1 Sigma 2 PD-L1 PARP IDH Alzheimer’s disease Parkinson’s disease β-amyloid plaques neurofibrillary tangles α-synucleinopathy diagnostic imaging probes orexin receptors PET radiotracer imaging alpha 7 nicotinic acetylcholine receptors nAChR autoradiography amino acid FET FACBC FDOPA immunoPET molecular imaging glioma brain metastases adenosine A2A receptor rotenone-based mouse model [18F]FESCH two-step one-pot radiosynthesis |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557295103321 |
Brust Peter
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of PPARs in Disease
| The Role of PPARs in Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico |
Medicine
Physiology |
| Soggetto non controllato |
peroxisome-proliferator activated receptors
tumor angiogenesis tumor progression metastasis formation endothelial cells RNA sequencing PPARs toxicology pharmacology ligand vascular coronary artery lipidomics eicosanoids inflammation CYP450 peroxisome proliferator-activated receptor angiogenesis proliferation metastasis immortality resistance to cell death growth suppressors immune system cellular metabolism PPAR nuclear receptors addiction alcohol nicotine opioids psychostimulants animal models human studies Alzheimer’s risk factors PPARα lipids fatty acids modulators cognition sex therapy hypertrophic adipocytes PPARG isoforms PPARG splicing dominant-negative isoform in vitro adipocytes adipogenesis hypertrophic obesity insulin-resistance peroxisome proliferator-activated receptors (PPARs) synthetic agonists non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) fibrosis Sirtuin1 peroxisome proliferator-activated receptor-γ coactivator-1α peroxisome proliferator activated receptors obesity metabolic syndrome vitamin B12 folate fetal programming inherited metabolic disorders PGC-1α, disease kidney cancer AKI CKD nephron PKD cilia cystogenesis ligands Alzheimer’s disease (AD) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482503321 |
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Wagner Nicole
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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