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Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing
| Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing |
| Autore | Pörtner Ralf |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (226 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
clonal cell population
phenotypic diversity inoculum train uncertainty-based cell culture model biopharmaceutical manufacturing Escherichia coli hybrid modeling machine learning model-assisted DoE quality by design upstream bioprocessing surface plasmon resonance (SPR) bioprocess monitoring biosensor quality by design (QbD) process analytical technology (PAT) biotherapeutics production vaccines production CHO DP-12 computational fluid dynamics bioreactor characterization hydrodynamic gradients process development critical shear stress Kolmogorov length scale operational space sensors cell culture spectroscopy PAT smart biomanufacturing soft-sensor Adeno-associated virus transfection PEI continuous gene therapy microcarriers bioreactor transient expression spheroid strength β-cells diabetes shear stress-guided production hydrodynamic stress Gaussian processes Bayes optimization Pareto optimization multi-objective seed train Chinese hamster ovary cells cryopreservation monoclonal antibodies N−1 perfusion process intensification upstream processing |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072803321 |
Pörtner Ralf
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Insights into Parvovirus Research
| New Insights into Parvovirus Research |
| Autore | Gallinella Giorgio |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto non controllato |
antivirals
Bombyx mori bidensovirus Bocaparvovirus human bocavirus 1 equine parvovirus-hepatitis NS2 NS1 X-ray crystallography BIRC3 (cIAP-2) glycans children antibody interactions new viruses alpaca cidofovir rodent protoparvoviruses clinical trials structural biology DNA virus human bocavirus caspase-3 viral communities uncoating PLA2 phospholipase-A2 oncolytic virus immune therapy Parvoviridae viral ecology Cryo-EM AAV metagenomics phylogeny oncolytic viruses mite parvovirus evolution Carnivore protoparvovirus 1 adeno-associated virus telbivudine capsid stability virus homology modeling human airway epithelia sequence analysis acute gastroenteritis bisulfite PCR next-generation sequencing single stranded DNA virus overlapping promoters virus diversity prognosis oncolytic activity genome hydroxyurea Lepidoptera genome externalization antiviral compounds circulating angiogenic cells tumor microenvironment coumarin derivatives nuclear targeting densovirus receptor interactions cell cycle arrest transcription profile brincidofovir canine parvovirus endogenous viral elements inflammatory cardiomyopathy erythroid progenitor cells RNA-seq insect chapparvovirus RT-qPCR trafficking AAV2 agricultural pests Adeno-associated virus myocarditis diagnosis parvovirus feline panleukopenia virus chitin B19V transcription mapping flavonoids immunomodulation erythrovirus apoptosis adenoviral vector anti-cancer divalent cations protease genetics preclinical arthropod peritrophins biocontrol dilated cardiomyopathy insect parvovirus combination therapies intravenous immunoglobulin (IVIG) virus phylogeny evolution second generation parvovirus treatments commercial horse serum parvovirus B19 canine chapparvovirus CpG methylation RACE H-1PV viral metagenomics horses |
| ISBN | 3-03928-311-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404088603321 |
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Gallinella Giorgio
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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