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Antitumoral Properties of Natural Products : Volume 2
| Antitumoral Properties of Natural Products : Volume 2 |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (300 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
13-ethylberberine
Akt AKT anthraquinones anti-cancer anti-cancer activity anti-cancer agents anti-tumor activity anticancer Antioxidant activities antioxidants antioxidation antiproliferation agents Antiproliferative antiproliferative activity antitumoral activity antrodin C apoptosis AR Artemisia absinthium ASE Aspergillus fumigatus ATM-Chk2 autophagic flux inhibition autophagy bee venom betulinic acid Brazilian Cerrado biome cancer cancer stem cells capsazepine carrageenan Catalpa speciosa Celastraceae cell cycle arrest cell proliferation cell signaling cephalotaxine cervical cancer Cheiloclinium cognatum chemotherapeutic adjuvant chemotherapy chiral resolution CIP2A CLE-10 CLEFMA Colocasia esculenta colorectal cancer cells copper Cordyceps sinensis coronarin D CrataBL cryptolepine Cucurbitacin B cytotoxic activity cytotoxicity Dendrobium officinale diallyl disulfide dicentrine DLD-1 cells doxorubicin drug resistance ECD calculation EGFR endoplasmic reticulum stress entrapment efficiency Euphorbia tirucalli FAK/S6K1 flavonoids folk medicine food bioactive FOXO1 fruit Ganoderma tsugae gastric cancer gastric cancer cells gefitinib-resistant NSCLC Gene expression glioblastoma glioblastoma multiforme glioma glucose uptake glycosyltransferase grape leaves human neuroblastoma cells IL-6/JAK2/STAT3 inflammation inflammatory diseases ingenol invasion isochromanes isocryptolepine JNK lactoferrin hydrolysate LC3 lichen Licochalcone A lipogenesis lung adenocarcinoma lysosomal degradation lysosomal membrane permeabilization Magnolia acuminata manganese MAPK MCF-7 cells MDA-MB-231 melanoma melittin mesenchymal stem cells metabolic stability metastasis microenvironment migration mitochondrial membrane potential mitochondrial ROS mitochondrial-dependent pathway molecular mechanism mTOR multiple myeloma n/a naringenin natural compounds natural product alkaloids natural products natural yellow Monascus pigments NCI-60 cancer cell line necrotic neferine neocryptolepine NF-κB no-toxicity Nutraceuticals oncogene osteosarcoma p38 patuletin phenols phloretin phytochemicals PI3K/AKT/mTOR PI3K/Akt/mTOR pathway plant lectin plant-derived foods plantation mode Plenckia populnea porphyran preclinical tests pristimerin pro-apoptotic effects proanthocyanins prostate cancer protease inhibitor protein kinase C protein synthesis inhibition Pulsatilla saponin D quality control quercetagetin quercetin ROS RT-R breast cancer cells Salacia crassifolia Salacia elliptica SB365 seaweed secondary metabolites semi-synthetic derivative SREBP-1 stable nanocapsules stemness potential structure activity relationships structure elucidation tarin Taxus cuspidata temozolomide TNF-α TP traditional preparation transcriptional regulation triterpenoids TRPV1 tumidulin ursolic acid vegetable water-soluble zerumbone Zeylenone |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antitumoral Properties of Natural Products |
| Record Nr. | UNINA-9910557531303321 |
Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antitumoral Properties of Natural Products
| Antitumoral Properties of Natural Products |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (344 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
13-ethylberberine
Akt AKT anthraquinones anti-cancer anti-cancer activity anti-cancer agents anti-tumor activity anticancer Antioxidant activities antioxidants antioxidation antiproliferation agents Antiproliferative antiproliferative activity antitumoral activity antrodin C apoptosis AR Artemisia absinthium ASE Aspergillus fumigatus ATM-Chk2 autophagic flux inhibition autophagy bee venom betulinic acid Brazilian Cerrado biome cancer cancer stem cells capsazepine carrageenan Catalpa speciosa Celastraceae cell cycle arrest cell proliferation cell signaling cephalotaxine cervical cancer Cheiloclinium cognatum chemotherapeutic adjuvant chemotherapy chiral resolution CIP2A CLE-10 CLEFMA Colocasia esculenta colorectal cancer cells copper Cordyceps sinensis coronarin D CrataBL cryptolepine Cucurbitacin B cytotoxic activity cytotoxicity Dendrobium officinale diallyl disulfide dicentrine DLD-1 cells doxorubicin drug resistance ECD calculation EGFR endoplasmic reticulum stress entrapment efficiency Euphorbia tirucalli FAK/S6K1 flavonoids folk medicine food bioactive FOXO1 fruit Ganoderma tsugae gastric cancer gastric cancer cells gefitinib-resistant NSCLC Gene expression glioblastoma glioblastoma multiforme glioma glucose uptake glycosyltransferase grape leaves human neuroblastoma cells IL-6/JAK2/STAT3 inflammation inflammatory diseases ingenol invasion isochromanes isocryptolepine JNK lactoferrin hydrolysate LC3 lichen Licochalcone A lipogenesis lung adenocarcinoma lysosomal degradation lysosomal membrane permeabilization Magnolia acuminata manganese MAPK MCF-7 cells MDA-MB-231 melanoma melittin mesenchymal stem cells metabolic stability metastasis microenvironment migration mitochondrial membrane potential mitochondrial ROS mitochondrial-dependent pathway molecular mechanism mTOR multiple myeloma n/a naringenin natural compounds natural product alkaloids natural products natural yellow Monascus pigments NCI-60 cancer cell line necrotic neferine neocryptolepine NF-κB no-toxicity Nutraceuticals oncogene osteosarcoma p38 patuletin phenols phloretin phytochemicals PI3K/AKT/mTOR PI3K/Akt/mTOR pathway plant lectin plant-derived foods plantation mode Plenckia populnea porphyran preclinical tests pristimerin pro-apoptotic effects proanthocyanins prostate cancer protease inhibitor protein kinase C protein synthesis inhibition Pulsatilla saponin D quality control quercetagetin quercetin ROS RT-R breast cancer cells Salacia crassifolia Salacia elliptica SB365 seaweed secondary metabolites semi-synthetic derivative SREBP-1 stable nanocapsules stemness potential structure activity relationships structure elucidation tarin Taxus cuspidata temozolomide TNF-α TP traditional preparation transcriptional regulation triterpenoids TRPV1 tumidulin ursolic acid vegetable water-soluble zerumbone Zeylenone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557419703321 |
|
Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Delivery of siRNA Therapeutics
| Drug Delivery of siRNA Therapeutics |
| Autore | Lamberti Gaetano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (288 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
AKT
amphiphilic dendrons angiogenesis antitumor effect aptamers asthma BCL2 BIRC5/survivin breast cancer cancer carbonate apatite cationic cholesterol derivative cationic liposome clinical trials covalent dendrimers delivery drug co-delivery drug delivery endoglin endothelial cells ERBB2 folate folate receptor gene knockdown gene silencing indocyanine green intracellular release iron oxide light-activated release lipid liposome liposomes magnetic nanoparticle methotrexate migration mixed micelles n/a NABDs nanoparticle nanoparticles nanovectors oligonucleotide delivery oral cancer ovarian cancer PAMAM dendrimers pegylation PEI peptide poly(ethylene) imine polyamine polyaspartamide polymer polyplexes proliferation RNA RNAi therapeutics self-assembling siRNA siRNA delivery STAT6 targeted delivery system tumor xenograft tumor-targeting tyrosine-modification VEGFA VEGFR1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557498903321 |
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Lamberti Gaetano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor
| Fibroblast Growth Factor Receptor (FGFR) Signaling Pathway in Tumor |
| Autore | Holzmann Klaus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (276 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adenocarcinoma of the esophagogastric junction
AKT anticancer astrocytoma autocrine signaling autophagy brain cancer breast cancer cancer cancer signaling cancer-associated fibroblasts coreceptor ERK ERK1/2 estrogen FGF FGF-mediated signaling FGF18 FGF19 FGF2 FGF8 FGFR FGFR1 FGFR2 FGFR2c FGFR4 fibroblast growth factor fibroblast growth factor receptors FRS2 gastric cancer gene regulation GPER HCC HEK293 immunohistochemistry infigratinib sensitivity inhibitors JNK1 keratinocyte kinase inhibitor LY2874455 malignant glioma malignant pleural mesothelioma melanoma membrane proteins monoclonal antibody MTOR n/a negative feedback loop neoadjuvant therapy neurite outgrowth NVP-BGJ398 optogenetics overall survival PC12 phosphorylation prognosis receptor cross-talk receptor kinase resistance review sarcoma seborrheic keratosis serine signaling skin small molecule Sprouty proteins squamous and basal cell carcinoma structure targeted therapy tumor promoter tumor suppressor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Fibroblast Growth Factor Receptor |
| Record Nr. | UNINA-9910557898903321 |
|
Holzmann Klaus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
mTOR in Human Diseases / Olivier Dormond
| mTOR in Human Diseases / Olivier Dormond |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN |
9783039210619
3039210610 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
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Dormond Olivier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Prognostic and Predictive Markers in Cancer Progression
| New Prognostic and Predictive Markers in Cancer Progression |
| Autore | Costantini Susan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (294 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acetyltransferase
AKT antigen processing machinery (APM) molecules AR biomarker biomarkers bladder cancer blood BRCA1/2 breast cancer cancer cancer immunotherapy cancer prognosis carcinogenesis cardioncology cardiotoxicity castration-resistant prostate cancer (CRPC) CD8+ T effector cells chemo-/radio resistance CSC CTCs cytokines EMT eribulin genetic syndromes genomic mutations head and neck cancer head and neck neoplasms head and neck tumors HRR HUB nodes human leukocyte antigen (HLA) hyperglycemia immune checkpoint inhibitor K-RAS oncogene laryngeal cancer lifestyle habit major histocompatibility complex (MHC) MAPK melanoma melanoma resistance to MAPK/MEK inhibitors metabolomics metastasis microRNA miRNA MSI2 mTOR musashi 2 mutations N-cadherin n/a NAA10 new metastasis nivolumab oncogene dependency oral cancer OSCC pancreatic cancer paraganglioma PDL1 pheochromocytoma PI3K PI3KCA prediction prognosis prostate cancer PTEN resistance to immune checkpoint inhibitors selenoproteins targeted therapies therapeutic resistance therapeutic target TILs TNBC transcriptomics tumor predisposition WNT |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557794803321 |
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Costantini Susan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases
| Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases |
| Autore | Kwok Hang Fai |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (180 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
AKT
amphibian Bowman-Birk inhibitor amyloidogenesis anionic lipids anti-inflammation anticancer therapy anticancer therapy/cancer treatment antifungal antioxidant apoptosis Asteraceae Astragalus membranaceus Bcl-2 family proteins binding affinity branched-chain fatty acids cell cycle arrest colorectal cancer Conidiobolus heterosporus COX-2 DAPK1 docetaxel drug delivery system drug design endoplasmic reticulum F23R variant fatty acid oxidation fibroblasts fucoidan G-protein activation gingiva hepatocyte hIAPP iNOS insulin insulin granules kynurenines lignan lipid metabolism lung cancer molecular cloning molecular docking n/a natural-based compound NO orientin PDX-1 peptides peroxisome proliferator-activated receptor α Petasites japonicus PGE2 pharmacophore PI3K PLGA pomegranate post-translational modification PPARγ protease inhibitor protein degradation punicalagin SENP STAT3 SUMO survivin tannins Tat peptide unfolded protein response wound healing β-cell cytotoxicity β-sheet transitions μ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607403321 |
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Kwok Hang Fai
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2
| Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2 |
| Autore | Luparello Claudio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (318 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
acute myeloid leukemia
adipocyte inflammation AKT AMPK angiogenesis anti-cancer drug anti-proliferative anticancer anticancer activities anticancer drug anticancer drugs AOM/DSS model apoptosis autophagy berberine Berthel bioactivities bioavailability brain cancer breast cancer breast cancer cells breast cancer prognostic breast cancer risk Calocedrus formosana cancer cancer metabolism cancer stem cell cancer therapy carrageenan caspase-independent cell death cell death cell signaling cell-cycle arrest chemoprevention colchicine alkaloid colon cancer colon cancer cells colorectal cancer daidzein daidzein metabolites drugs EGCG EGFR signaling EGFR TKI eicosapentaenoic acid epigallocatechin-3-gallate (EGCG) epithelial mesenchymal transition ER stress estrogen estrogen receptor alpha ethanol experimental therapeutics FASN inhibitors flavonoids formononetin fucoidan G2/M arrest gallic acid gemcitabine gigantol gliomas glucose transport glycolysis glycolytic markers HDAC HO-1 honokiol human cancer cells immunotherapy inflammation innate immunity invasion isobolography isorhamnetin JAK/STAT lung cancer malignant cancer malignant tumors of the peripheral nerve sheath (MPNST) Malva pseudolavatera Webb & mangrove marine sponge mechanism melanoma cells mesoporous silica nanoparticles metastasis microRNAs MMPs molecular mechanisms multiple myeloma n/a nanoparticle-based delivery systems natural anti-inflammatory compounds natural bioactive compound natural compounds natural polyphenols natural product neurofibromas nicotine nobiletin non-coding RNAs Nrf2 NSCLC nutrition obesity oleacein oleuropein olive leaf extract oncogenic cascades oral cancer inhibition p53 paclitaxel pancreatic cancer PD-1 immune checkpoint inhibitor and cancer immunotherapy PD-L1 persistent organic pollutants phosphofructokinase phytochemicals Piper eriopodon, alkenylphenols polyphenols preclinical models pro-resolving lipids proteomics RacGAP1 radiotherapy reactive oxygen species renin-angiotensin system resistance ROS schwannomas Seahorse analysis signaling pathways signalling pathway small organic agents STAT3 Streptomyces systematic review targeted delivery system TRAIL tumor density tumor maintenance uterine sarcoma xenograft Xenopus laevis XIAP antagonists XIAP-BIR3 domain yatein α9-nAChR β-glucans |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Role of Natural Bioactive Compounds in the Rise and Fall of Cancers |
| Record Nr. | UNINA-9910557476303321 |
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Luparello Claudio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Targeting STAT3 and STAT5 in Cancer
| Targeting STAT3 and STAT5 in Cancer |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (578 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
ADAM17
adoptive T cell therapy AKT androgens apoptosis autoimmune disease autosomal-dominant hyper IgE syndrome Bone Marrow Failure Syndromes breast cancer cancer cancer models cancer progression cancer-stem cell CD38 CD4+ T cells CD8+ T cells cell cycle cell hierarchy chaperones chemotherapy resistance cirrhosis colon cancer companion animals comparative oncology cytokine cytokine receptor signaling dynamic programming endoplasmic reticulum (ER) stress epidermal growth factor receptor (EGF-R) ERK1/2 escape mechanisms gain-of-function mutation glioblastoma glioma growth hormone insensitivity syndrome heat shock proteins hedging hematopoietic cancers hepatitis C virus (HCV) hepatocellular carcinoma (HCC) hepatocyte nuclear factor 4 alpha (HNF4A) immune check point immune suppression immunosuppression immunotherapy inflammation inflammation associated cancer inflammatory hepatocellular adenomas interleukin-6 JAK JAK family of protein tyrosine kinases JAK2 V617F knockout lipopolyplex lung cancer lymphocytes lymphoma M2 macrophages melanoma meta-analysis metalloprotease metastasis microRNA-122 (miR-122) mitochondria MPN mTOR multiple myeloma mutations myeloid cells myeloid leukemia n/a nanoparticle neoplastic stem cells NGS NK cells nuclear factor erythroid 2-related factor 2 (NRF2) nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling ovarian cancer oxidative stress (OS) PD-L1 PEI pharmacological inhibitor pharmacological inhibitors polyethylenimine post-decision state variable prolactin proliferation prostate cancer RHOA risk management S3I-1757 SH2 domain shedding signal transducer and activator of transcription signal transducer and activator of transcription 3 (STAT3) siRNA delivery siRNA/RNAi small-molecule inhibitors solid cancers stabilization STAT STAT transcription factors STAT3 STAT3 inhibitor XIII STAT5 STAT5 signaling STAT5B signaling stem/progenitor cells stemness T-cell large granular lymphocytic leukemia T-cell leukemia T-cell prolymphocytic leukemia T-cells T-PLL targeted therapy targeting therapeutic targeting therapy resistance trans-signaling transaction costs tumor microenvironment tumor necrosis factor alpha (TNFα) tumor suppression tumor-associated macrophages tumor-immune cell interactions tumorigenesis tyrosine kinase 2 unfolded protein response (UPR) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557623503321 |
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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