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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (606 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
1,2,3-triazole
2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide 3,6-dibromocarbazole 4-(pyridin-4-yloxy)benzamide 5-bromoindole 5-fluorouracil ABCB1 (P-glycoprotein) actin ADME allene amides/esters androgen receptor anti-cancer activity anti-neuroinflammation anti-ovarian cancer anti-tumor anticancer anticancer activity anticancer agent anticancer agents anticancer compounds antimitotic agents antioxidant activity antiproliferative activity antiproliferative agent antitumor antitumor activity apalutamide apoptosis aromatase benzimidazole benzofuran-pyrazole benzofurans beta-lapachone bivalency breast cancer c-Met carbazole cell cycle chemical synthesis chemoresistance chrysin analogues colchiceine colchicine amide colchicine analogs colchicine sulfonamide colon cancer computational docking coumarin crystal structure cyanopyridone cytotoxic activity cytotoxic properties cytotoxicity darolutamide DFT study dihydroartemisinin dihydropyranoindole docking docking studies drug discovery drug resistance E-stereoselective enzalutamide enzyme inhibition estrone derivatives flavonoid flavonoids gemcitabine HDAC inhibitors HeLa HepG2 hydrates hydrazine IGF-1R IL-12 immune modulation indoleamine 2,3-dioxygenase inflammation inhibitor K562 kinase inhibitor MCF-7 MDM2-p53 interaction migration mimetics molecular simulation MOLT-4 multidrug resistance (MDR) reversal N-substituted pyrazoline nanoparticles natural product neuroblastoma NIH3T3 o-nitro-benzyl organosilicon compounds ortho-quinones ovarian cancer overcoming drug resistance P-glycoprotein P-MAPA PARP inhibitor PARP-1 inhibition phenylpyrazolopyrimidine photoactivatable protecting groups PI3Ks PI3Kα inhibitor PI3Kδ inhibitors polyvalency prodrug prostate cancer PROTACs protein degradation protein kinase protein-protein interactions Pyrazole pyrazolopyridine pyridotriazine quinazolin-4(3H)-one quinazolin-4(3H)-thione regioselective salinomycin Schiff base SILA-409 (Alis-409) SILA-421 (Alis-421) Src substituted pyridine synergy synthesis Talazoparib tanshione IIA taxoids thiazolidinone Thienopyrimidine thienopyrimidinone thiocolchicine thiopene thioxotriazopyridine TLR signaling topoisomerase II inhibitor triazolothiadiazine triple-negative breast cancer tryptophan metabolism tubulin inhibitors tumor specificity urea virtual screening xanthones yeast-based assays zampanolide βIII-tubulin |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug-Drug Interactions
| Drug-Drug Interactions |
| Autore | Kim Dong Hyun |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (242 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
(‒)-sophoranone
1A2 2B6 2C19 2C8 2C9 2D6 3A4 ADME adverse drug reactions biflavonoid chronic kidney disease competitive inhibition computational prediction CYP CYP1A1 CYP1A2 CYP2C9 CYP2D6 CYP3A CYP3A4 cytochrome P450 cytochromes P450 DDI Dexamethasone drug interaction drug interactions drug metabolism drug transporter drug-drug interaction drug-drug interactions expression fexofenadine gepants high plasma protein binding in silico in vitro in vivo inhibitor ixazomib Ketoconazole lasmiditan Lexicomp low permeability Loxoprofen mechanism-based inhibition metabolic DDI metabolism migraine monoclonal antibodies non-competitive inhibition O-desmethyltramadol OATP1B1 OATP1B3 organic anion transporting polypeptide 1A2 (OATP1A2) P-glycoprotein (P-gp) P450 pharmacokinetics physiologically-based pharmacokinetics plasma concentration polypharmacy potent inhibition QSAR regulation Rumex acetosa selamariscina A signal detection algorithms spontaneous reporting systems subset analysis substrate systemic exposure tadalafil ticagrelor tissue-specific tramadol tyrosine kinase inhibitors ubiquitination uridine 5'-diphosphoglucuronosyl transferase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557666403321 |
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Kim Dong Hyun
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Drug Research in China: Selected Papers from the 15-NASMD Conference
| Marine Drug Research in China: Selected Papers from the 15-NASMD Conference |
| Autore | Zhou Xuefeng |
| Descrizione fisica | 1 online resource (512 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
absolute configuration
AChE inhibitory actinomycete actinomycin D actinomycin X2 adenosine monophosphate-activated protein kinase (AMPK) ADME ADMET adsorption kinetics and isotherms angiotensin-I-converting enzyme (ACE) peptide Antarctic krill (Euphausia superba) anti-glioma activity anti-inflammatory activity antiaging antibacterial antibacterial activity antibacterial properties anticancer antihyperlipidemic antimicrobial activity antimicrobial peptides antioxidant activity antitumor activity antitumor peptide apoptosis Arca inflata aromatic acids ascidian-derived fungus Aspergillus flavipes HN4-13 Aspergillus hiratsukae Aspergillus puniceus Aspergillus sclerotiorum Aspergillus sp Aspergillus terreus Aspergillus unguis biological activities butenolides butyrolactone I Caenorhabditis elegans calmodulin CDK4/6 chejuenlide chronic kidney disease clavipitacae cognitive dysfunction colorectal cancer coral-derived fungi cyclic pentapeptide cytotoxic activity cytotoxicity deep-sea actinomycetes deep-sea fungus deep-sea-derived fungus depsides depsidones Diaporthe sp drug design dyeing emodin enantiomers endothelin-1 (ET-1) enrichment eremophilane sesquiterpenoids flavonoid fluorescent properties food allergy fucoidan fucoxanthin galaxamide analogues genome mining geodin GSK3β-Nrf2-HO-1 signaling Hahella heterocornols IL-17 pathway insecticidal activity isoquinoline alkaloid LC-MS/MS Lecanicillium fusisporum lipodepsipeptide macroporous resin XAD-16 mangrove endophytic Pestalotiopsis mangrove-derived fungus MAPK signaling marine compounds marine fungi mechanism meroterpenoids metabolism methicillin-resistant Staphylococcus aureus microbial pigments microbiota microglial polarization mm-pbsa molecular docking molecular dynamics mutants NAFLD nasopharyngeal carcinoma neuroinflammation nitric oxide (NO) Nrf2 nuclear factor erythroid-2-related factor 2-mediated (Nrf2) Oceanapia osteoclast differentiation oxidative stress oxidized low-density lipoprotein oximes oyster pancreatic lipase PD-L1 Penicillium sp peptide peptidome Pestalotiopsis heterocornis pharmacokinetics pharmacophore construction pharmacophore modeling phycocyanin piericidins plasma prodiginine protein tyrosine phosphatase inhibitor pyranodipyran derivatives sclerotides Sdy-1 secondary metabolites semisynthesize sesquiterpene glycoside signaling pathway silk skipjack tuna (Katsuwonus pelamis) muscle soft-coral-derived fungus Sonneratia apetala sponge sponge-derived fungus stability Streptomyces parvulus tetramic acid derivatives Toll-like receptor 4-mediated (TLR4) transcriptome Trichoderma longibrachiatum tyrosyl DNA phosphodiesterase 1 inhibitory activities vascular endothelial cell virtual screening Wnt signaling xanthones β-catenin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Marine Drug Research in China |
| Record Nr. | UNINA-9910595071903321 |
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Zhou Xuefeng
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| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Additives in Food
| Natural Additives in Food |
| Autore | Barros Lillian |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (290 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
absorption
added value products ADME Allium cepa red cv animal breeding anionic chelating biopolymers anthocyanin anthocyanins anti-melanogenic anti-oxidant antimicrobial antimicrobial activity antioxidant antioxidant ability antioxidant activity antioxidants B16 melanoma cell beetroot bergenin beta cyclodextrin betalains bioactive compounds bis(2-methyl-3-furyl) disulfide (BMFDS) black carrot black rice flour by-products byproducts Caenorhabditis elegans casein gels cheese chemometrics chlorophyllin chlorophylls cholesterol cholesterol extraction Citrus limon colorants coloring foodstuff copper-chlorophyll cyanidin 3-rutinoside egg yolk Endopleura uchi enzyme modified soymilk essential oil ewe's milk ex vivo colon fermentation extra virgin olive oil extraction optimization foaming capacity and emulsifiers food additives food colors food industry granules extraction green colorant heat and ultrasound assisted extraction Heat-Assisted Extraction horchata de chufa Huntington in vitro human gastrointestinal digestion leaf addition lifespan lipids low gluten muffins malonildialdehyde Manchego microbial transglutaminase microstructures natural colorants natural extract Ocimum basilicum var. purpurascens leaves oxidation products oxygen-containing sulfur flavor molecules peonidin 3-rutinoside phenolics pickling polyphenols pomelo peel Prunus spinosa L. fruit epicarp red rubin basil rennet induced gelation response surface methodology rheological properties semi-preparative RP-HPLC skim milk solvent extraction soymilk SPME stress resistance tetraethyl orthosilicate textural properties texturizing agents tiger nut tocopherols traditional medicine triple TOF-LC-MS-MS trisodium citrate Tunisian varieties Urtica spp uxi volatiles wild fruit valorization zinc-chlorophylls β-carotene |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580210003321 |
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Barros Lillian
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers
| Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers |
| Autore | Kutner Andrzej |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (450 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
1,2,4-triazole
25 vitamin D 24-hydroxylase A-ring active substance delivery systems active substance-controlled release ADME alkaloids alpha-ketoglutarate analogue actions at genes anti-depressant therapy anti-inflammatory activity anticancer activity anticancer drug anticancer drugs antidepressants antimalarial antimicrobial activity antimicrobial compounds antimicrobial peptide (AMP) antioxidant activity antiparasitic agents antiviral proteins apoptosis Au(III) complex biomarker biomedical hydrogels calcilytic calcimimetic calcium-sensing receptor cancer cancer cells cancer therapy cancer treatment CD-ring cell cycle cell invasion cell migration Chelidonium majus ChIP-chip analysis colon cancer colorectal cancer copper (II) complexes CRISPR/Cas9 cyclooxygenase CYP24A1 CYP24A1-dependent metabolism CYP27B1 cytotoxic activity cytotoxic study cytotoxicity defense-related proteins depression dermaseptin distal enhancers drug drug design drug design and discovery drug discovery dual 5-HT1A/SERT activity electrochemistry enantiomer fluorine frog skin peptides genistein genome editing glucose metabolism glycoconjugates gold gold electrode greater celandine hemolysis high-grade serous ovarian cancer cells histone deacetylase (HDAC) histone H3 acetylation HT-29 human DNA topoisomerase hydrogels for cosmetology hydrogels for dermatology IL-8 inflammation JNK latex LHRH lung cancer major latex protein MALDI metabolite metallodrugs methotrexate molecular docking molecular modeling multimodal activity n/a nanoparticles organometallic oxidation mechanisms Phyllomedusa bicolor Plasmodium falciparum (P. falciparum) PRI-2191 proliferation prostate cancer proteome analysis pyridazinone pyrido[1,2-c]pyrimidines resveratrol rickets RNA polymerase II SAR self-assembled monolayer side-chain spectroscopic data split luciferase-based biosensor stereospecificity synthesis targeted therapy tetrahydro-β-carbolines TGF-β therapeutic peptides thiourea transcription transdermal active substance delivery systems VEGF vitamin D vitamin D analogs vitamin D biology and action vitamin D hormone (1,25(OH)2D3) vitamin D receptor vitamin D3 Warburg effect |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585938903321 |
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Kutner Andrzej
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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