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A Meeting of Minds: In Recognition of the Contributions of Randall J. Cohrs
| A Meeting of Minds: In Recognition of the Contributions of Randall J. Cohrs |
| Autore | Grose Charles |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (424 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
varicella-zoster virus
Oka strain human herpesvirus 6 human herpesvirus 7 corticosteroids serious adverse event herpes zoster IL-6 IL-10 innate immunity VLT VLT-ORF63 CRISPR/Cas9 BAC mutagenesis flavivirus SARS-CoV-2 pandemic preparedness host-virus interactions prion vaccines interferon lambda virus herpes simplex virus type 1 herpes simplex virus type 2 neonatal herpesvirus infection HSV UL6 herpesvirus encephalitis herpesvirus hepatitis acyclovir HerpeSelect test viral sequencing HELLP syndrome lipids dengue virus acyl-CoA acyl-CoA thioesterase fatty acids membranes rheostat fatty acyl-CoA Marek's disease virus live-cell genome visualization lytic replication T cells latency genome integration TetO/TetR system varicella zoster virus reactivation genome cleavage AAV antiviral therapies HSV-1 cornea trigeminal ganglia interferon-γ interferon stimulatory genes TRIM21 HSV EBV KSHV MHV68 PIC transcription productive elongation mRNA rRNA tRNA herpes viral reactivation spaceflight dermatitis stress immune depression antiviral drugs bacterial artificial chromosome luciferase bioluminescence imaging skin organ culture humanized mice β-Coronavirus mouse hepatitis virus-A59/MHV-A59 mouse hepatitis virus-2/MHV2 spike protein fusion peptide/FP cell-to-cell fusion (fusogenicity) neuropathogenesis hepatitis demyelination structural rigidity simian varicella virus herpesvirus varicella VZV neuro-attenuated ORF7 vaccine antiviral COVID-19 drug discovery coronavirus spike protein Mpro RdRp PLpro skin epidermis keratinocytes epidermal differentiation cutaneous blistering lesions keratins autophagy immunity human neuron culture non-coding RNA CD8 T cell T-cell epitope NK cell KIR3DL1 HLA-B*57:01 herpes simplex virus zoster skin pathogenesis HSV-2 neurons cell culture varicella-zoster gene expression ganglion autopsy saliva salivary VZV DNA dengue viruses Aedes aegypti adaptive mutation |
| ISBN | 3-0365-5260-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Meeting of Minds |
| Record Nr. | UNINA-9910619471403321 |
Grose Charles
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (494 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
ABC transporters
drug action regulatory extension regulatory insertion mechanism of action MRP1 MRP4 breast cancer proliferation migration invasion cAMP ABCG2 ABCB1 blood-brain barrier PET Alzheimer's disease beta-amyloid tariquidar erlotinib ABCG5 ABCG8 ATP-binding cassette transporter cholesterol polar relay sitosterolemia 5' untranslated region cis-acting elements ABCA subfamily bioinformatics ABC transporter therapy response disease-free survival next-generation sequencing competitive allele-specific PCR P-glycoprotein amyloid-beta neuron SK-N-SH gene therapy AAV PFIC BSEP ABCB11 bile salts intrahepatic cholestasis chaperones PFIC2 BRIC ATP-binding cassette transporter A1 (ABCA1) cholesterol homeostasis reverse cholesterol transport HDL-C dyslipidemia type 2 diabetes microparticles ABCG2 genotype clinico-genetic analysis ethnic specificity genetic variations precision medicine rare variant Roma serum uric acid SUA-lowering therapy urate transporter bile secretion ABCB4 ABCC2 ABCG5/G8 molecular partners phytosterol xenosterol atherosclerosis gall stone ABC transporter ABC (ATP-binding cassette) transporters multidrug resistance transport trafficking urate mutations polymorphisms ABCC6 TNAP NT5E Pseudoxanthoma elasticum (PXE) cancer membrane protein functional divergence calcification pseudoxanthoma elasticum generalized arterial calcification of infancy pyrophosphate therapies ABCA7 phagocytosis Aβ peptides yeast multidrug transporter anticancer antifungal resistance mechanism peroxisome adrenoleukodystrophy fatty acids gout early-onset gout hyperuricemia uric acid BCRP single nucleotide polymorphism SNP homology modeling substrate-binding site cellular ATP efflux mutagenesis intracellular traffic MDR3 phosphatidylcholine RAB GTPase taxol drug transport |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
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Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Parvovirus Research 2020
| Advances in Parvovirus Research 2020 |
| Autore | Gallinella Giorgio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
feline parvovirus
virus-like particles VP2 protein antibodies AAV neuro-degenerative disease gene therapy antigenicity sequencing virus canine parvovirus peri-urban wild dogs disease transmission Australia parvovirus B19 G-quadruplex bioinformatics antivirals BRACO-19 pyridostatin oncolytic viruses rodent protoparvovirus H-1PV virus entry clathrin-mediated endocytosis parvovirus minute virus of mice RNA processing gene expression canine COVID-19 veterinary epidemiology B19V VP1u receptor PLA2 erythroid cells biomarker drug delivery nanocarrier B19 parvovirus detection cell cycle permissivity serotype capsid cryo-EM genome packaging gene delivery bocavirus Caribbean region new CPV-2a outbreak endemic nearly complete genomes virus evolution parvoviruses nucleus imaging of viral interactions and dynamics analysis of protein–protein interactions analysis of virus–chromatin interactions AMDV Aleutian disease mink parvovirus Aleutian mink disease virus vaccine |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557370403321 |
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Gallinella Giorgio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Therapies for Inherited Retinal Diseases
| Molecular Therapies for Inherited Retinal Diseases |
| Autore | Collin Rob W.J |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (262 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
induced pluripotent stem cell (iPSC)
clustered regularly interspaced short palindromic repeats (CRISPR) homology-directed repair (HDR) Enhanced S-Cone Syndrome (ESCS) NR2E3 AAV retina gene therapy dual AAV gold nanoparticles DNA-wrapped gold nanoparticles ARPE-19 cells retinal pigment epithelium clathrin-coated vesicles endosomal trafficking retinitis pigmentosa autosomal dominant G56R putative dominant negative effect gapmer antisense oligonucleotides allele-specific knockdown Leber congenital amaurosis and allied retinal ciliopathies CEP290 Flanders founder c.4723A > T nonsense mutation Cilia elongation spontaneous nonsense correction AON-mediated exon skipping microRNA photoreceptors rods cones bipolar cells Müller glia retinal inherited disorders retinal degeneration antisense oligonucleotides Stargardt disease inherited retinal diseases splicing modulation RNA therapy ABCA4 iPSC-derived photoreceptor precursor cells cyclic GMP apoptosis necrosis drug delivery systems translational medicine Usher syndrome Leber congenital amaurosis RPE65 nonprofit patient registry translational protein trafficking protein folding protein degradation chaperones chaperonins heat shock response unfolded protein response autophagy therapy IRD DNA therapies RNA therapies compound therapies clinical trials Retinitis Pigmentosa GTPase Regulator adeno-associated viral Retinitis Pigmentosa (RP) choroideremia REP1 inherited retinal disease treatment apical polarity crumbs complex fetal retina PAR complex retinal organoids retinogenesis gene augmentation adeno-associated virus (AAV) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674051103321 |
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Collin Rob W.J
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Insights into Parvovirus Research
| New Insights into Parvovirus Research |
| Autore | Gallinella Giorgio |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto non controllato |
antivirals
Bombyx mori bidensovirus Bocaparvovirus human bocavirus 1 equine parvovirus-hepatitis NS2 NS1 X-ray crystallography BIRC3 (cIAP-2) glycans children antibody interactions new viruses alpaca cidofovir rodent protoparvoviruses clinical trials structural biology DNA virus human bocavirus caspase-3 viral communities uncoating PLA2 phospholipase-A2 oncolytic virus immune therapy Parvoviridae viral ecology Cryo-EM AAV metagenomics phylogeny oncolytic viruses mite parvovirus evolution Carnivore protoparvovirus 1 adeno-associated virus telbivudine capsid stability virus homology modeling human airway epithelia sequence analysis acute gastroenteritis bisulfite PCR next-generation sequencing single stranded DNA virus overlapping promoters virus diversity prognosis oncolytic activity genome hydroxyurea Lepidoptera genome externalization antiviral compounds circulating angiogenic cells tumor microenvironment coumarin derivatives nuclear targeting densovirus receptor interactions cell cycle arrest transcription profile brincidofovir canine parvovirus endogenous viral elements inflammatory cardiomyopathy erythroid progenitor cells RNA-seq insect chapparvovirus RT-qPCR trafficking AAV2 agricultural pests Adeno-associated virus myocarditis diagnosis parvovirus feline panleukopenia virus chitin B19V transcription mapping flavonoids immunomodulation erythrovirus apoptosis adenoviral vector anti-cancer divalent cations protease genetics preclinical arthropod peritrophins biocontrol dilated cardiomyopathy insect parvovirus combination therapies intravenous immunoglobulin (IVIG) virus phylogeny evolution second generation parvovirus treatments commercial horse serum parvovirus B19 canine chapparvovirus CpG methylation RACE H-1PV viral metagenomics horses |
| ISBN | 3-03928-311-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404088603321 |
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Gallinella Giorgio
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Application of Viruses to Biotechnology
| The Application of Viruses to Biotechnology |
| Autore | Varanda Carla |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (296 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
Bacteriophage
Salmonella biocontrol comparative genomics phage diversity grapevine apple latent spherical virus vector virus-induced flowering reduced generation time breeding of grapevine virus elimination Newcastle disease virus reverse genetics vaccines infectious diseases cancer porcine epidemic diarrhea virus VLP chemokines pig vaccine SARS-CoV-2 COVID-19 phages CRISPR viruses prevention diagnosis treatment adeno-associated virus (AAV) vector jaagsiekte sheep retrovirus (JSRV) LTR enhancer transduction viral vaccines cancers COVID-19 vaccines self-replicating RNA vectors DNA-based vaccines RNA-based vaccines plant virus viroid viral vector virus-induced gene silencing (VIGS) CRISPR/Cas9 genome editing carotenoid biosynthesis circular RNA infectious bursal disease virus immunization recombinant Lactococcus lactis variant strain baculovirus insect cells bacmid Tn7 genome stability protein expression chikungunya virus VLPs bioreactor CRISPR/Cas systems viral vectors gene editing plant genome engineering viral resistance adeno-associated virus AAV cancer gene therapy prophage hydrothermal vent Hypnocyclicus thermotrophus lytic cassette Escherichia coli heterologous expression codon optimization codon harmonization expression vectors aspect ratio VNPs TMV PVX CPMV geminivirus theranostics CRISPR-cas9 clodronate macrophage gene therapy gene expression nanotechnology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557363903321 |
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Varanda Carla
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Understanding Neuromuscular Health and Disease: Advances in Genetics, Omics, and Molecular Function
| Understanding Neuromuscular Health and Disease: Advances in Genetics, Omics, and Molecular Function |
| Autore | Duddy William |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
LMNA
Emery-Dreifuss muscular dystrophy Omics ALS MND ALS variants genotype-phenotype ALS genes FSHD DUX4 transcription muscle regulation spinal muscular atrophy adult patients disease heterogeneity Nusinersen disease modifiers functional outcomes biomarkers epigenetic changes -omics approaches oxidative stress mitochondria dysfunction axonal transport autophagy endocytosis secretion excitotoxicity RNA metabolism Duchenne muscular dystrophy (DMD) exon-skipping therapies next-generation sequencing (NGS) Sanger sequencing multiplex ligation probe amplification (MLPA) multiplex polymerase chain reaction (PCR) comparative genomic hybridization array (CGH) viltolarsen eteplirsen golodirsen rheumatoid arthritis SNP DMARD methotrexate pharmacogenomics Duchenne muscular dystrophy pharmacodynamic biomarkers prednisone deflazacort glucocorticoids corticosteroids safety neuromuscular diseases translational research disease models precision medicine miRNA proteomics calprotectin dystrophy Becker muscular dystrophy dystrophinopathy genotype-phenotype correlations Canadian Neuromuscular Disease Registry reading frame rule dystrophin multiple logistic regression analysis exon skipping therapy Amyotrophic Lateral Sclerosis machine learning genome-wide association studies GWAS genomics ALS pathology gene prioritization AAV genetic neuromuscular disorders gene therapy clinical trials toxicity SMA DMD XLMTM facioscapulohumeral dystrophy TALEN CRISPR-Cas9 gene editing polyadenylation D4Z4 duchenne muscular dystrophy (DMD) becker muscular dystrophy (BMD) exon skipping skip-equivalent deletions |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Understanding Neuromuscular Health and Disease |
| Record Nr. | UNINA-9910557669103321 |
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Duddy William
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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