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Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing
| Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing |
| Autore | Pörtner Ralf |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (226 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
clonal cell population
phenotypic diversity inoculum train uncertainty-based cell culture model biopharmaceutical manufacturing Escherichia coli hybrid modeling machine learning model-assisted DoE quality by design upstream bioprocessing surface plasmon resonance (SPR) bioprocess monitoring biosensor quality by design (QbD) process analytical technology (PAT) biotherapeutics production vaccines production CHO DP-12 computational fluid dynamics bioreactor characterization hydrodynamic gradients process development critical shear stress Kolmogorov length scale operational space sensors cell culture spectroscopy PAT smart biomanufacturing soft-sensor Adeno-associated virus transfection PEI continuous gene therapy microcarriers bioreactor transient expression spheroid strength β-cells diabetes shear stress-guided production hydrodynamic stress Gaussian processes Bayes optimization Pareto optimization multi-objective seed train Chinese hamster ovary cells cryopreservation monoclonal antibodies N−1 perfusion process intensification upstream processing |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072803321 |
Pörtner Ralf
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Phospholipases: From Structure to Biological Function
| Phospholipases: From Structure to Biological Function |
| Autore | Balboa María A |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (348 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
inhibitor
metabolic stability α-methylation oxoesters phospholipase A2 adrenic acid arachidonic acid mass spectrometry lipid signaling inflammation monocytes/macrophages crotoxin snake venom lung impairment inflammatory response lipid mediators neuromuscular blocker lipidomics PAP-2 autotaxin lysophosphatidate G protein-coupled receptor PLA2G6 fatty liver phospholipid remodeling diet-induced obesity morbidly obesity choline and methionine deficiency glioblastoma sphingolipid sphingosine-1-phosphate sphingomyelinase sphingomyelin metastasis phosphatidic acid diacylglycerol lipin signaling cPLA2α psoriasis proliferation anti-inflammatory atherosclerosis phospholipases macrophages T cells lipins pancreatic islets β-cells insulin secretion glucose tolerance insulin resistance group VIA phospholipase A2 fatty acid knockout mouse lipid mediator lysophospholipid membrane phospholipid ceramide acidic sphingomyelinase neutral sphingomyelinase hepatocellular carcinoma alcoholic and nonalcoholic steatohepatitis preadipocytes prostaglandins adipokines cytokines EP receptors Group V phospholipase A2 lipids majeed syndrome LPIN2 LIPIN2 chronic non-bacterial osteomyelitis chronic recurrent multifocal osteomyelitis autoinflammatory inflammasome macrophage osteoclast |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Phospholipases |
| Record Nr. | UNINA-9910576879603321 |
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Balboa María A
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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