Hallmarks of Parkinson’s Disease |
Autore | Alves Da Costa Cristine |
Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
Descrizione fisica | 1 electronic resource (124 p.) |
Soggetto topico |
Medicine
Neurosciences |
Soggetto non controllato |
Parkinson’s disease
unfolded protein response reticulum endoplasmic genetics alpha-synuclein prion-like spreading cell-to-cell transfer neurodegeneration mitochondrial dysfunction PINK1 neurons astrocytes microglia α-synuclein exocytosis lipids membranes Parkinson disease SNARE complex synapse vesicle fusion therapeutic target protein quality control mitochondrial quality control ubiquitin alpha-syn mitophagy Parkin mito-Keima mito-QC mito-SRAI |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910595069503321 |
Alves Da Costa Cristine | ||
Basel, : MDPI Books, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Oligonucleotide, Therapy, and Applications |
Autore | Aliño Salvador |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (123 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
quantum dots (QDs)
DNAzyme ROS Amplex Red light-induced activity DNA methylation histone code microRNA nanoparticles noncoding RNA pulmonary arterial hypertension aptamer aptasensor influenza SERS virus detection α-synuclein antisense oligonucleotide dopamine neurotransmission double mutant A30P*A53T* motor deficits Parkinson’s disease transgenic mouse model G-quadruplexes covalent dimer construct anti-proliferative activity primary cell culture of human glioma antisensense oligonucleotide Foxp3 regulatory T cells vaccine immunogenicity Sporothrix schenckii Marfan syndrome fibrillin-1 antisense oligonucleotides exon skipping splice-switching |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557615903321 |
Aliño Salvador | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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P38 Signaling Pathway |
Autore | Cuenda Ana |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (194 p.) |
Soggetto topico | Research & information: general |
Soggetto non controllato |
arginine methylation
erythroid differentiation MKK3 phosphorylation, PRMT1 p38 MAPK cocaine conditioned place preference reward stress anxiety depression nucleus accumbens social interaction k opioid receptors p38α Rab5 endosome Alzheimer's Lewy Bodies amyloid-β tau α-synuclein p38-MAPK α inhibitor Alzheimer's disease synaptic plasticity neuroinflammation β-amyloid Tau Kv4.2 seizure temporal lobe epilepsy hippocampus neuronal firing and excitability p38MAPK nuclear translocation β-like importins inflammation cancer skeletal muscle energy metabolism signal transduction exercise type 2 diabetes p38 mitogen-activated protein kinase bleomycin-induced pulmonary fibrosis idiopathic pulmonary fibrosis RNA sequencing alveolar epithelial type II cells MAPK p38 physiology metabolism signaling hypoxia arrhythmia MAPK11 p38β |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557702003321 |
Cuenda Ana | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Ubiquitination in Health and Diseases |
Autore | Ishigami Tomoaki |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (292 p.) |
Soggetto topico |
Humanities
Social interaction |
Soggetto non controllato |
deubiquitinase
degradation therapeutic target cancer hematopoiesis hematopoietic stem cells immune response regulation of gene expression ubiquitin system genetic diseases ubiquitin ligase deubiquitinases monoubiquitin signaling vesicular trafficking protein complex formation inflammation inhibitor innate immune interferon LUBAC NF-κB ubiquitin Parkinson’s disease dopa-responsive dystonia tyrosine hydroxylase α-synuclein fatty acid-binding protein 3 ubiquitination proteasomal degradation ubiquitin-proteasome system mitochondria E3 ubiquitin ligase MITOL/MARCH5 salt-sensitive hypertension Nedd4L/Nedd4-2 epithelial sodium channel aldosterone sensitive distal nephron excitation-transcription coupling RNF183 RNF186 RNF182 RNF152 RING finger mTOR endoplasmic reticulum stress osmotic stress ubiquitin code virus infection virus-host interaction tau protein semisynthesis disulfide-coupling polyubiquitin fibrils aggregation neurodegeneration deubiquitination inhibitors protein quality control proteolysis protein stabilization regulatory T cells mesenchymal stem cell cortical bone derived stem cell myocardial infarction blood pressure renal salt reabsorption vascular function ubiquitin proteasome system ubiquitin–proteasome pathway cilia ciliogenesis differentiation proliferation ciliopathy E3s DUBs UPS neurodegenerative disease immune-related diseases |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557356403321 |
Ishigami Tomoaki | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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