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Clinical xenotransplantation : pathways and progress in the transplantation of organs and tissues between species / / David K. C. Cooper, Guerard Byrne, editors
| Clinical xenotransplantation : pathways and progress in the transplantation of organs and tissues between species / / David K. C. Cooper, Guerard Byrne, editors |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2020] |
| Descrizione fisica | 1 online resource (XXIX, 306 p. 82 illus., 59 illus. in color.) |
| Disciplina | 617.95 |
| Soggetto topico |
Xenografts
Transplantation, Heterologous |
| ISBN | 3-030-49127-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Clinical and Experimental Xenotransplantation: Background -- 1. A brief history of clinical cross-species organ xenotransplantation -- 2. The pathobiology of pig-to-primate xenotransplantation: a historical review -- 3. Is sensitization to pig antigens detrimental to subsequent allotransplantation? -- 4. Sensitization to human leukocyte antigens and xenotransplantation? -- Pig Kidney and Heart Xenotransplantation in Nonhuman Primates – the Present Position -- 5. Kidney xenotransplantation in nonhuman primates -- 6. Cardiac xenotransplantation in nonhuman primates -- Organ-source Pig Genetic Engineering and Regulation -- 7. Gene-edited pigs for xenotransplantation -- 8. Addressing regulatory requirements for the organ-source pig – a pragmatic approach to facility design and pathogen prevention -- Antibody-Mediated Allotransplant Rejection: Lessons for Xenotransplantation -- 9. Antibody-mediated graft rejection in nonhuman primate models: comparison of sensitized allotransplant and xenotransplant rejection -- 10. Management of anti-HLA antibodies and acute antibody-mediated rejection -- 11. Evolving approaches to treatment of allosensitization and antibody-mediated rejection -- 12. Lessons from ABO-incompatible cardiac allotransplantation in the newborn -- Patient Evaluation and Selection for First Clinical Trials of Kidney or Heart Xenotransplantation -- 13. Defining an “acceptable risk threshold” – who should be the first kidney xenotransplant recipient? -- 14. Selection of patients for initial clinical trials of kidney xenotransplantation -- 15. Selection of patients for initial clinical trials of cardiac xenotransplantation -- 16. Selection of pediatric patients for initial clinical trials of cardiac xenotransplantation -- 17. Infection in xenotransplantation: organ-source health and patient safety -- 18. Histocompatibility testing for xenotransplantation -- Regulatory, Economic, and Social Aspects of Clinical Trials of Xenotransplantation -- 19. Xenotransplantation; the FDA perspective -- 20. Xenotransplantation: a payer’s perspective -- 21. Public perceptions towards clinical trials of organ xenotransplantation -- Summation -- 22. What did the workshop achieve? |
| Record Nr. | UNINA-9910420951003321 |
| Cham, Switzerland : , : Springer, , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Contested technologies [[electronic resource] ] : xenotransplantation and human embryonic stem cells / / Anders Persson & Stellan Welin
| Contested technologies [[electronic resource] ] : xenotransplantation and human embryonic stem cells / / Anders Persson & Stellan Welin |
| Autore | Persson Anders |
| Pubbl/distr/stampa | Lund, Sweden, : Nordic Academic Press, 2008 |
| Descrizione fisica | 1 online resource (213 p.) |
| Disciplina | 617.95 |
| Soggetto topico |
Xenografts
Embryonic stem cells |
| Soggetto genere / forma | Electronic books. |
| ISBN | 91-87121-79-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Copyright; Contents; Preface; 1. Background, positions, controversies; 1.1 The rise of molecular medicine; 1.2 Aims and limitations of the book; 1.3 Theoretical perspectives and central concepts; 1.4 The role of the observer; 1.5 Methods and material; 1.6 Outline of the book; 2. Xenotransplantation: development and controversies; 2.1 Introduction; 2.2 A short history of xenotransplantation; 2.3 Regulative efforts; 2.4 PERV and the call for a worldwide moratorium; 2.5 The lobbyists: patient organisations and animal rights activists; 2.6 The controversy in the political arena
2.7 The boundaries of the human body2.8 Knock-out pigs and some recent developments; 3. The ethics of early clinical trials; 3.1 The research regime: science versus ethics; 3.2 The Baby Fae case, or, was xenotransplantation premature?; 3.3 The last primate trials and the risk of viral infections; 3.4 Pig islets to diabetes patients: from low-risk research to PERV risk; 3.5 Extra-corporal transfusion through pig kidneys; 3.6 Going south: the Valdés-González case; 3.7 The way forward; 4. Human embryonic stem cells: developments and debates; 4.1 Human embryonic stem cells and the embryo 4.2 The British embryo research debate4.3 The Swedish debate on hESC research; 4.4 Rhetorical strategies; 4.5 A Presidential decision and its consequences; 4.6 Avoiding the human embryo: adult stem cells; 4.7 The end of controversy? An American epilogue; 5. The commercialisation of biomedical science; 5.1 The changing landscapes of biomedical research funding; 5.2 The role of patents and the control of biological material; 5.3 The commercialisation of stem cell research; 5.4 The Swedish stem cell companies; 5.5 Commercialisation and research ethics; 5.6 Science by press release 5.7 Science on the run5.8 Some concluding remarks; 6. Summing up: risk, therapies, values, and vested interests; 6.1 The xenotransplantation and hESC controversies compared; 6.2 The involvement of commercial interests; 6.3 Involving the public: consultations, surveys, and social consent; 6.4 The therapeutic imperative and global inequality; References |
| Record Nr. | UNINA-9910453224403321 |
Persson Anders
|
||
| Lund, Sweden, : Nordic Academic Press, 2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Contested technologies [[electronic resource] ] : xenotransplantation and human embryonic stem cells / / Anders Persson & Stellan Welin
| Contested technologies [[electronic resource] ] : xenotransplantation and human embryonic stem cells / / Anders Persson & Stellan Welin |
| Autore | Persson Anders |
| Pubbl/distr/stampa | Lund, Sweden, : Nordic Academic Press, 2008 |
| Descrizione fisica | 1 online resource (213 p.) |
| Disciplina | 617.95 |
| Soggetto topico |
Xenografts
Embryonic stem cells |
| Soggetto genere / forma | Electronic books. |
| ISBN | 91-87121-79-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Copyright; Contents; Preface; 1. Background, positions, controversies; 1.1 The rise of molecular medicine; 1.2 Aims and limitations of the book; 1.3 Theoretical perspectives and central concepts; 1.4 The role of the observer; 1.5 Methods and material; 1.6 Outline of the book; 2. Xenotransplantation: development and controversies; 2.1 Introduction; 2.2 A short history of xenotransplantation; 2.3 Regulative efforts; 2.4 PERV and the call for a worldwide moratorium; 2.5 The lobbyists: patient organisations and animal rights activists; 2.6 The controversy in the political arena
2.7 The boundaries of the human body2.8 Knock-out pigs and some recent developments; 3. The ethics of early clinical trials; 3.1 The research regime: science versus ethics; 3.2 The Baby Fae case, or, was xenotransplantation premature?; 3.3 The last primate trials and the risk of viral infections; 3.4 Pig islets to diabetes patients: from low-risk research to PERV risk; 3.5 Extra-corporal transfusion through pig kidneys; 3.6 Going south: the Valdés-González case; 3.7 The way forward; 4. Human embryonic stem cells: developments and debates; 4.1 Human embryonic stem cells and the embryo 4.2 The British embryo research debate4.3 The Swedish debate on hESC research; 4.4 Rhetorical strategies; 4.5 A Presidential decision and its consequences; 4.6 Avoiding the human embryo: adult stem cells; 4.7 The end of controversy? An American epilogue; 5. The commercialisation of biomedical science; 5.1 The changing landscapes of biomedical research funding; 5.2 The role of patents and the control of biological material; 5.3 The commercialisation of stem cell research; 5.4 The Swedish stem cell companies; 5.5 Commercialisation and research ethics; 5.6 Science by press release 5.7 Science on the run5.8 Some concluding remarks; 6. Summing up: risk, therapies, values, and vested interests; 6.1 The xenotransplantation and hESC controversies compared; 6.2 The involvement of commercial interests; 6.3 Involving the public: consultations, surveys, and social consent; 6.4 The therapeutic imperative and global inequality; References |
| Record Nr. | UNINA-9910540175403321 |
|
Persson Anders
|
||
| Lund, Sweden, : Nordic Academic Press, 2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Xenotransplantation : comprehensive study / / edited by Shuji Miyagawa
| Xenotransplantation : comprehensive study / / edited by Shuji Miyagawa |
| Pubbl/distr/stampa | London, United Kingdom : , : IntechOpen, , [2020] |
| Descrizione fisica | 1 online resource (156 pages) : illustrations |
| Disciplina | 617.95 |
| Soggetto topico | Xenografts |
| ISBN | 1-78985-664-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Xenotransplantation |
| Record Nr. | UNINA-9910409744903321 |
| London, United Kingdom : , : IntechOpen, , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Xenotransplantation : comprehensive study / / edited by Shuji Miyagawa
| Xenotransplantation : comprehensive study / / edited by Shuji Miyagawa |
| Pubbl/distr/stampa | London : , : IntechOpen, , 2020 |
| Descrizione fisica | 1 online resource (156 pages) |
| Disciplina | 617.95 |
| Soggetto topico | Xenografts |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Xenotransplantation |
| Record Nr. | UNINA-9910688571103321 |
| London : , : IntechOpen, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Xenotransplantation
| Xenotransplantation |
| Pubbl/distr/stampa | [Oxford, England], : Blackwell Pub |
| Descrizione fisica | 1 online resource |
| Disciplina | 617.95 |
| Soggetto topico |
Xenografts
Transplantation of organs, tissues, etc Transplantation, Heterologous Transplantation Heterotransplantation Zeitschrift Online-Ressource Hétérogreffe |
| Soggetto genere / forma |
Periodical
Periodicals. Périodique électronique (Descripteur de forme) Ressource Internet (Descripteur de forme) |
| ISSN | 1399-3089 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996212460403316 |
| [Oxford, England], : Blackwell Pub | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Xenotransplantation
| Xenotransplantation |
| Pubbl/distr/stampa | [Oxford, England], : Blackwell Pub |
| Descrizione fisica | 1 online resource |
| Disciplina | 617.95 |
| Soggetto topico |
Xenografts
Transplantation of organs, tissues, etc Transplantation, Heterologous Transplantation Heterotransplantation Zeitschrift Online-Ressource Hétérogreffe |
| Soggetto genere / forma |
Periodical
Periodicals. Périodique électronique (Descripteur de forme) Ressource Internet (Descripteur de forme) |
| ISSN | 1399-3089 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910146482403321 |
| [Oxford, England], : Blackwell Pub | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Xenotransplantation and risk : regulating a developing biotechnology / / Sara Fovargue [[electronic resource]]
| Xenotransplantation and risk : regulating a developing biotechnology / / Sara Fovargue [[electronic resource]] |
| Autore | Fovargue Sara <1971-> |
| Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , 2012 |
| Descrizione fisica | 1 online resource (xiii, 291 pages) : digital, PDF file(s) |
| Disciplina | 344.04/194 |
| Collana | Cambridge law, medicine, and ethics |
| Soggetto topico |
Xenografts
Transplantation immunology Xenografts - Moral and ethical aspects Transplantation of organs, tissues, etc |
| ISBN |
1-107-22347-4
1-280-48477-2 9786613579751 1-139-22181-7 1-139-21699-6 1-139-22352-6 1-139-21392-X 1-139-22009-8 1-139-02692-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introducing the issues -- Dealing with risk -- Regulating experimental procedures and medical research -- Regulatory responses to developing biotechnologies -- Challenges to legal and ethical norms : first party consent and third parties at risk -- Surveillance and monitoring : balancing public health and individual freedom -- Summary and concluding thoughts : looking to the future. |
| Altri titoli varianti | Xenotransplantation & Risk |
| Record Nr. | UNINA-9910461004603321 |
|
Fovargue Sara <1971->
|
||
| Cambridge : , : Cambridge University Press, , 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Xenotransplantation and risk : regulating a developing biotechnology / / Sara Fovargue [[electronic resource]]
| Xenotransplantation and risk : regulating a developing biotechnology / / Sara Fovargue [[electronic resource]] |
| Autore | Fovargue Sara <1971-> |
| Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , 2012 |
| Descrizione fisica | 1 online resource (xiii, 291 pages) : digital, PDF file(s) |
| Disciplina | 344.04/194 |
| Collana | Cambridge law, medicine, and ethics |
| Soggetto topico |
Xenografts
Transplantation immunology Xenografts - Moral and ethical aspects Transplantation of organs, tissues, etc |
| ISBN |
1-139-20910-8
1-107-22347-4 1-280-48477-2 9786613579751 1-139-22181-7 1-139-21699-6 1-139-22352-6 1-139-21392-X 1-139-22009-8 1-139-02692-5 |
| Classificazione | LAW093000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introducing the issues -- Dealing with risk -- Regulating experimental procedures and medical research -- Regulatory responses to developing biotechnologies -- Challenges to legal and ethical norms : first party consent and third parties at risk -- Surveillance and monitoring : balancing public health and individual freedom -- Summary and concluding thoughts : looking to the future. |
| Altri titoli varianti | Xenotransplantation & Risk |
| Record Nr. | UNINA-9910789706403321 |
|
Fovargue Sara <1971->
|
||
| Cambridge : , : Cambridge University Press, , 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Xenotransplantation and risk : regulating a developing biotechnology / / Sara Fovargue [[electronic resource]]
| Xenotransplantation and risk : regulating a developing biotechnology / / Sara Fovargue [[electronic resource]] |
| Autore | Fovargue Sara <1971-> |
| Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , 2012 |
| Descrizione fisica | 1 online resource (xiii, 291 pages) : digital, PDF file(s) |
| Disciplina | 344.04/194 |
| Collana | Cambridge law, medicine, and ethics |
| Soggetto topico |
Xenografts
Transplantation immunology Xenografts - Moral and ethical aspects Transplantation of organs, tissues, etc |
| ISBN |
1-139-20910-8
1-107-22347-4 1-280-48477-2 9786613579751 1-139-22181-7 1-139-21699-6 1-139-22352-6 1-139-21392-X 1-139-22009-8 1-139-02692-5 |
| Classificazione | LAW093000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introducing the issues -- Dealing with risk -- Regulating experimental procedures and medical research -- Regulatory responses to developing biotechnologies -- Challenges to legal and ethical norms : first party consent and third parties at risk -- Surveillance and monitoring : balancing public health and individual freedom -- Summary and concluding thoughts : looking to the future. |
| Altri titoli varianti | Xenotransplantation & Risk |
| Record Nr. | UNINA-9910810579703321 |
|
Fovargue Sara <1971->
|
||
| Cambridge : , : Cambridge University Press, , 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
