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Vitamin B12 and B12-proteins [[electronic resource] ] : lectures presented at the 4th European Symposium on Vitamin B12 and B12-Proteins / / edited by Bernhard Kräutler, Duilio Arigoni and Bernard T. Golding
| Vitamin B12 and B12-proteins [[electronic resource] ] : lectures presented at the 4th European Symposium on Vitamin B12 and B12-Proteins / / edited by Bernhard Kräutler, Duilio Arigoni and Bernard T. Golding |
| Pubbl/distr/stampa | Weinheim ; ; Chichester, : Wiley-VCH, c1998 |
| Descrizione fisica | 1 online resource (560 p.) |
| Disciplina | 572.58 |
| Altri autori (Persone) |
KräutlerBernhard
ArigoniDuilio GoldingBernard T |
| Soggetto topico |
Vitamin B12
Vitamin B12 - Synthesis Vitamin B12 - Structure-activity relationships |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-76388-8
9786611763886 3-527-61219-X 3-527-61218-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Vitamin B12 and B12-Proteins; Contents; I B12: An Overview; 1. B12 Coenzymes, the Central Theme; II B12: Biosynthesis; 2. B12-Biosynthesis in an Aerobic Organism: How the Pathway was Elucidated; 3. Vitamin B12 Biosynthesis in Pseudomonas denitrificans; 4. How Nature Synthesizes B12 Without Oxygen: Discoveries Along the Ancient, Anaerobic Pathway; 5. The Biosynthesis of Vitamin B12: Assembly of the Tetrapyrrole Ring System; 6. Investigations on the Biosynthesis of the 5,6- Dimethylbenzimidazole Moiety of Vitamin B12; III Bl2-Proteins: Enzymatic Methyltransfer
7. Cobdamin-Dependent Methionine Synthase from Escherichia coli: Structure and Reactivity8. EPR Spectroscopic Evidence That in the Energy Conserving Methyltransferase Complex from Methanogenic Archaea a Histidine Residue is Ligated to the Cobamide-Cobalt; 9. Discovery of a Biological Organometallic Reaction Sequence Involving Vitamin B12; 10. Corrinoid-Dependent Methyl Transfer Reactions in Sporomusa ovata; 11 Spectroscopic and Molecular Genetic Characterization of the Two Mammalian B12-Dependent Enzymes; IV B12-Proteins: Enzymatic Rearrangements 12 A Mechanistic Overview of B12 Dependent Processes13 Insights on the Reaction Mechanism of Methylmalonyl-CoA Mutase from the Crystal Structure; 14. Tritium Isotope Effects and Site-Directed Mutagenesis as Probes of the Reaction Catalyzed by Methylmalonyl-CoA Mutase; 15 Mechanism of Coenzyme B12-Dependent Carbon-Carbon and Carbon-Oxygen Rearrangements; 16. Glutamate Mutase; 17. Isobutyryl-CoA Mutase from Streptomycetes; 18. Coenzyme B12-Dependent Enzymes and Their Models; 19. Model Studies for the Methylmalonyl-Succinyl Rearrangements 20. Recent Structure-Function Studies of B12 Coenzymes in Diol Dehydrase21 Adenosylcobalamin-Dependent Ribonucleotide Reductases: Still Amazing but no Longer Confusing; V BI2 : Structure and Reactivity; 22. High-Resolution Crystal Structures of Cobalamins; 23. New NMR Structural and Dynamical Probes of Organometallic B12 Derivatives; 24 FT-Raman Spectroscopy of Methyl-B12 and of Imidazole and Imidazolate Methylcobinamide Derivatives; 25 Coenzyme B12-Based Chemical Precedent for Co-C Bond Homolysis and Other Key Elementary Steps 26. Insight into the Mechanism of B12-Dependent Enzymes: Magnetic Field Effects as a Probe of Reaction Mechanism and the Role of the Ribofuranose Ring Oxygen27. Cage Effects and Diastereomeric Control in the Breaking and Making of Carbon-Cobalt Bonds in Organocobalt Corrinoids; VI Without B12 and With B12 ?; 28. The Role of S-Adenosylmethionine As a Poor Man's Adenosylcobalamin in the Reaction of Lysine 2,3- Aminomutase; 29. New Structural and Biosynthetic Aspects of the Unusual Core Lipids from Archaebacteria; VII B12 : Medical Aspects; 30. Cobalamin Binding Proteins 31. Cellular Surface Receptors Important for Vitamin B12 Nutrition |
| Record Nr. | UNINA-9910144279103321 |
| Weinheim ; ; Chichester, : Wiley-VCH, c1998 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Vitamin B12 and B12-proteins [[electronic resource] ] : lectures presented at the 4th European Symposium on Vitamin B12 and B12-Proteins / / edited by Bernhard Kräutler, Duilio Arigoni and Bernard T. Golding
| Vitamin B12 and B12-proteins [[electronic resource] ] : lectures presented at the 4th European Symposium on Vitamin B12 and B12-Proteins / / edited by Bernhard Kräutler, Duilio Arigoni and Bernard T. Golding |
| Pubbl/distr/stampa | Weinheim ; ; Chichester, : Wiley-VCH, c1998 |
| Descrizione fisica | 1 online resource (560 p.) |
| Disciplina | 572.58 |
| Altri autori (Persone) |
KräutlerBernhard
ArigoniDuilio GoldingBernard T |
| Soggetto topico |
Vitamin B12
Vitamin B12 - Synthesis Vitamin B12 - Structure-activity relationships |
| ISBN |
1-281-76388-8
9786611763886 3-527-61219-X 3-527-61218-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Vitamin B12 and B12-Proteins; Contents; I B12: An Overview; 1. B12 Coenzymes, the Central Theme; II B12: Biosynthesis; 2. B12-Biosynthesis in an Aerobic Organism: How the Pathway was Elucidated; 3. Vitamin B12 Biosynthesis in Pseudomonas denitrificans; 4. How Nature Synthesizes B12 Without Oxygen: Discoveries Along the Ancient, Anaerobic Pathway; 5. The Biosynthesis of Vitamin B12: Assembly of the Tetrapyrrole Ring System; 6. Investigations on the Biosynthesis of the 5,6- Dimethylbenzimidazole Moiety of Vitamin B12; III Bl2-Proteins: Enzymatic Methyltransfer
7. Cobdamin-Dependent Methionine Synthase from Escherichia coli: Structure and Reactivity8. EPR Spectroscopic Evidence That in the Energy Conserving Methyltransferase Complex from Methanogenic Archaea a Histidine Residue is Ligated to the Cobamide-Cobalt; 9. Discovery of a Biological Organometallic Reaction Sequence Involving Vitamin B12; 10. Corrinoid-Dependent Methyl Transfer Reactions in Sporomusa ovata; 11 Spectroscopic and Molecular Genetic Characterization of the Two Mammalian B12-Dependent Enzymes; IV B12-Proteins: Enzymatic Rearrangements 12 A Mechanistic Overview of B12 Dependent Processes13 Insights on the Reaction Mechanism of Methylmalonyl-CoA Mutase from the Crystal Structure; 14. Tritium Isotope Effects and Site-Directed Mutagenesis as Probes of the Reaction Catalyzed by Methylmalonyl-CoA Mutase; 15 Mechanism of Coenzyme B12-Dependent Carbon-Carbon and Carbon-Oxygen Rearrangements; 16. Glutamate Mutase; 17. Isobutyryl-CoA Mutase from Streptomycetes; 18. Coenzyme B12-Dependent Enzymes and Their Models; 19. Model Studies for the Methylmalonyl-Succinyl Rearrangements 20. Recent Structure-Function Studies of B12 Coenzymes in Diol Dehydrase21 Adenosylcobalamin-Dependent Ribonucleotide Reductases: Still Amazing but no Longer Confusing; V BI2 : Structure and Reactivity; 22. High-Resolution Crystal Structures of Cobalamins; 23. New NMR Structural and Dynamical Probes of Organometallic B12 Derivatives; 24 FT-Raman Spectroscopy of Methyl-B12 and of Imidazole and Imidazolate Methylcobinamide Derivatives; 25 Coenzyme B12-Based Chemical Precedent for Co-C Bond Homolysis and Other Key Elementary Steps 26. Insight into the Mechanism of B12-Dependent Enzymes: Magnetic Field Effects as a Probe of Reaction Mechanism and the Role of the Ribofuranose Ring Oxygen27. Cage Effects and Diastereomeric Control in the Breaking and Making of Carbon-Cobalt Bonds in Organocobalt Corrinoids; VI Without B12 and With B12 ?; 28. The Role of S-Adenosylmethionine As a Poor Man's Adenosylcobalamin in the Reaction of Lysine 2,3- Aminomutase; 29. New Structural and Biosynthetic Aspects of the Unusual Core Lipids from Archaebacteria; VII B12 : Medical Aspects; 30. Cobalamin Binding Proteins 31. Cellular Surface Receptors Important for Vitamin B12 Nutrition |
| Record Nr. | UNINA-9910830833803321 |
| Weinheim ; ; Chichester, : Wiley-VCH, c1998 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Vitamin B12 and B12-proteins : lectures presented at the 4th European Symposium on Vitamin B12 and B12-Proteins / / edited by Bernhard Krautler, Duilio Arigoni and Bernard T. Golding
| Vitamin B12 and B12-proteins : lectures presented at the 4th European Symposium on Vitamin B12 and B12-Proteins / / edited by Bernhard Krautler, Duilio Arigoni and Bernard T. Golding |
| Pubbl/distr/stampa | Weinheim ; ; Chichester, : Wiley-VCH, c1998 |
| Descrizione fisica | 1 online resource (560 p.) |
| Disciplina | 572.58 |
| Altri autori (Persone) |
KrautlerBernhard
ArigoniDuilio GoldingBernard T |
| Soggetto topico |
Vitamin B12
Vitamin B12 - Synthesis Vitamin B12 - Structure-activity relationships |
| ISBN |
1-281-76388-8
9786611763886 3-527-61219-X 3-527-61218-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Vitamin B12 and B12-Proteins; Contents; I B12: An Overview; 1. B12 Coenzymes, the Central Theme; II B12: Biosynthesis; 2. B12-Biosynthesis in an Aerobic Organism: How the Pathway was Elucidated; 3. Vitamin B12 Biosynthesis in Pseudomonas denitrificans; 4. How Nature Synthesizes B12 Without Oxygen: Discoveries Along the Ancient, Anaerobic Pathway; 5. The Biosynthesis of Vitamin B12: Assembly of the Tetrapyrrole Ring System; 6. Investigations on the Biosynthesis of the 5,6- Dimethylbenzimidazole Moiety of Vitamin B12; III Bl2-Proteins: Enzymatic Methyltransfer
7. Cobdamin-Dependent Methionine Synthase from Escherichia coli: Structure and Reactivity8. EPR Spectroscopic Evidence That in the Energy Conserving Methyltransferase Complex from Methanogenic Archaea a Histidine Residue is Ligated to the Cobamide-Cobalt; 9. Discovery of a Biological Organometallic Reaction Sequence Involving Vitamin B12; 10. Corrinoid-Dependent Methyl Transfer Reactions in Sporomusa ovata; 11 Spectroscopic and Molecular Genetic Characterization of the Two Mammalian B12-Dependent Enzymes; IV B12-Proteins: Enzymatic Rearrangements 12 A Mechanistic Overview of B12 Dependent Processes13 Insights on the Reaction Mechanism of Methylmalonyl-CoA Mutase from the Crystal Structure; 14. Tritium Isotope Effects and Site-Directed Mutagenesis as Probes of the Reaction Catalyzed by Methylmalonyl-CoA Mutase; 15 Mechanism of Coenzyme B12-Dependent Carbon-Carbon and Carbon-Oxygen Rearrangements; 16. Glutamate Mutase; 17. Isobutyryl-CoA Mutase from Streptomycetes; 18. Coenzyme B12-Dependent Enzymes and Their Models; 19. Model Studies for the Methylmalonyl-Succinyl Rearrangements 20. Recent Structure-Function Studies of B12 Coenzymes in Diol Dehydrase21 Adenosylcobalamin-Dependent Ribonucleotide Reductases: Still Amazing but no Longer Confusing; V BI2 : Structure and Reactivity; 22. High-Resolution Crystal Structures of Cobalamins; 23. New NMR Structural and Dynamical Probes of Organometallic B12 Derivatives; 24 FT-Raman Spectroscopy of Methyl-B12 and of Imidazole and Imidazolate Methylcobinamide Derivatives; 25 Coenzyme B12-Based Chemical Precedent for Co-C Bond Homolysis and Other Key Elementary Steps 26. Insight into the Mechanism of B12-Dependent Enzymes: Magnetic Field Effects as a Probe of Reaction Mechanism and the Role of the Ribofuranose Ring Oxygen27. Cage Effects and Diastereomeric Control in the Breaking and Making of Carbon-Cobalt Bonds in Organocobalt Corrinoids; VI Without B12 and With B12 ?; 28. The Role of S-Adenosylmethionine As a Poor Man's Adenosylcobalamin in the Reaction of Lysine 2,3- Aminomutase; 29. New Structural and Biosynthetic Aspects of the Unusual Core Lipids from Archaebacteria; VII B12 : Medical Aspects; 30. Cobalamin Binding Proteins 31. Cellular Surface Receptors Important for Vitamin B12 Nutrition |
| Record Nr. | UNINA-9910877882103321 |
| Weinheim ; ; Chichester, : Wiley-VCH, c1998 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
