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Assessment of future scientific needs for live variola virus [[electronic resource] /] / Committee on the Assessment of Future Scientific Needs for Live Variola Virus, Board on Global Health, Institute of Medicine
| Assessment of future scientific needs for live variola virus [[electronic resource] /] / Committee on the Assessment of Future Scientific Needs for Live Variola Virus, Board on Global Health, Institute of Medicine |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1999 |
| Descrizione fisica | 1 online resource (126 p.) |
| Disciplina | 616.9/12 |
| Collana | The compass series |
| Soggetto topico |
Smallpox - Research
Smallpox - Prevention Smallpox vaccine Virology - Cultures and culture media |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-18599-6
9786610185993 0-309-59698-X 0-585-06800-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910455904503321 |
| Washington, D.C., : National Academy Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Assessment of future scientific needs for live variola virus / / Committee on the Assessment of Future Scientific Needs for Live Variola Virus, Board on Global Health, Institute of Medicine
| Assessment of future scientific needs for live variola virus / / Committee on the Assessment of Future Scientific Needs for Live Variola Virus, Board on Global Health, Institute of Medicine |
| Pubbl/distr/stampa | Washington, D.C. : , : National Academy Press, , 1999 |
| Descrizione fisica | 1 online resource (126 pages) : illustrations |
| Disciplina | 616.9/12 |
| Collana | The compass series |
| Soggetto topico |
Smallpox - Research
Smallpox - Prevention Smallpox vaccine Virology - Cultures and culture media |
| ISBN |
0-309-17319-1
1-280-18599-6 9786610185993 0-309-59698-X 0-585-06800-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910778650803321 |
| Washington, D.C. : , : National Academy Press, , 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Assessment of future scientific needs for live variola virus / / Committee on the Assessment of Future Scientific Needs for Live Variola Virus, Board on Global Health, Institute of Medicine
| Assessment of future scientific needs for live variola virus / / Committee on the Assessment of Future Scientific Needs for Live Variola Virus, Board on Global Health, Institute of Medicine |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1999 |
| Descrizione fisica | 1 online resource (126 pages) : illustrations |
| Disciplina | 616.9/12 |
| Collana | The compass series |
| Soggetto topico |
Smallpox - Research
Smallpox - Prevention Smallpox vaccine Virology - Cultures and culture media Variola virus Smallpox - prevention & control Containment of Biohazards |
| ISBN |
9786610185993
9780309173193 0309173191 9781280185991 1280185996 9780309596985 030959698X 9780585068008 0585068003 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Assessment of Future Scientific Needs for Live Variola Virus -- Copyright -- Preface -- Acknowledgments -- REVIEWERS -- Contents -- Executive Summary -- SCOPE -- SCIENTIFIC NEEDS FOR LIVE AND REPLICATION-DEFECTIVE VARIOLA VIRUS -- OVERALL CONCLUSIONS -- Part I Introduction -- 1 Introduction -- BACKGROUND -- CONTEMPORARY CONTEXT -- SCOPE -- SCIENTIFIC NEEDS FOR VARIOLA VIRUS -- ORGANIZATION OF THIS REPORT -- Part II Smallpox and Its Control -- 2 Variola Virus and Other Orthopoxviruses -- GENERAL ATTRIBUTES OF ORTHOPOXVIRUSES -- POXVIRUS REPLICATION -- PROPERTIES OF SPECIFIC ORTHOPOXVIRUSES -- 3 Clinical Features of Smallpox -- ENTRY AND INFECTION -- DISSEMINATION -- THE RASH -- LESIONS OF THE MUCOUS MEMBRANES -- EFFECTS ON OTHER ORGANS -- IMMUNE RESPONSE -- IMMUNITY AGAINST SMALLPOX -- 4 Epidemiology -- CHARACTERISTICS OF HISTORICAL OUTBREAKS -- LIKELY CHARACTERISTICS OF FUTURE SMALLPOX OUTBREAKS -- CONTROL STRATEGIES -- 5 Variola Virus Stocks Following Eradication of Smallpox -- ESTABLISHMENT OF INTERNATIONAL REPOSITORIES -- DECISION BY THE WORLD HEALTH ASSEMBLY TO DESTROY VARIOLA VIRUS STOCKS -- U.S. RESEARCH ON SMALLPOX -- RESEARCH AT CDC AND USAMRIID -- Part III Scientific Needs for Variola Virus -- 6 Development of Antiviral Agents -- IN VITRO ASSAYS -- ANIMAL MODELS -- 7 Development of Vaccines -- CURRENT STATUS OF VACCINIA VACCINE PREPARATIONS -- EVALUATION OF VACCINIA VACCINE DERIVED FROM TISSUE CULTURE -- EVALUATION OF NOVEL VACCINES -- 8 Detection and Diagnosis -- ENVIRONMENTAL DETECTION -- DIAGNOSIS OF INFECTION -- ALTERNATIVES TO LIVE VIRUS -- 9 Bioinformatics -- VARIABILITY OF VARIOLA VIRUS -- POTENTIAL DEVELOPMENTS -- 10 Understanding of the Biology of Variola Virus -- VIRUS-CELL INTERACTIONS -- VIRUS-HOST INTERACTIONS -- 11 Research on the Expressed Protein Products of Variola -- SYNTHESIS OF VARIOLA PROTEINS.
POTENTIAL UTILITY OF VARIOLA PROTEINS -- Part IV Findings -- 12 Summary and Conclusions -- THE BROADER CONTEXT -- SCIENTIFIC NEEDS FOR LIVE VARIOLA VIRUS -- OVERALL CONCLUSIONS -- References -- Appendix A Glossary -- Appendix B Acronyms -- Appendix C Committee and Staff Biographies -- Staff. |
| Altri titoli varianti | Live variola virus |
| Record Nr. | UNINA-9910961761803321 |
| Washington, D.C., : National Academy Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Growth control in cell cultures [[electronic resource] ] : a Ciba Foundation Symposium / / edited by G.E.W. Wolstenholme and Julie Knight
| Growth control in cell cultures [[electronic resource] ] : a Ciba Foundation Symposium / / edited by G.E.W. Wolstenholme and Julie Knight |
| Pubbl/distr/stampa | London, : Churchill Livingstone, 1971 |
| Descrizione fisica | 1 online resource (298 p.) |
| Disciplina |
591.8/7
591.87 |
| Altri autori (Persone) |
WolstenholmeG. E. W (Gordon Ethelbert Ward)
KnightJulie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Tissue culture
Virology - Cultures and culture media |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-76847-9
9786613679246 0-470-71981-8 0-470-71746-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GROWTH CONTROL IN CELL CULTURES; Contents; Chairman's introduction; Studies of serum factors required by 3T3 and SV3T3 cells; Discussion; Conditions affecting the response of cultured cells to serum; Discussion; Factors controlling the multiplication of untransformed and transformed BHK2l cells under various environmental conditions; Discussion; The significance of surface structure changes for growth control under crowded conditions; Discussion; Regulation of cell multiplication in tissue culture; Discussion; Molecular exchange and growth control in tissue culture; Discussion
Attempts to isolate SV40 transformation factorDiscussion; Growth regulation in cultures of chick embryo fibroblasts; Discussion; SV40 transformation and cellular growth control; Discussion; Growth control between dissimilar cells in culture; Discussion; Specific growth regulation in early subcultures of human diploid fibroblasts; Discussion; Transport and phospholipid changes related to control of growth in 3T3 cells; Discussion; Aspects of membrane structure and function in Escherichia coli; Discussion; General Discussion; Chairman's closing remarks Appendix: growth properties of normal and trans- formed cellsAuthor index; Subject index |
| Record Nr. | UNINA-9910144669603321 |
| London, : Churchill Livingstone, 1971 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Growth control in cell cultures [[electronic resource] ] : a Ciba Foundation Symposium / / edited by G.E.W. Wolstenholme and Julie Knight
| Growth control in cell cultures [[electronic resource] ] : a Ciba Foundation Symposium / / edited by G.E.W. Wolstenholme and Julie Knight |
| Pubbl/distr/stampa | London, : Churchill Livingstone, 1971 |
| Descrizione fisica | 1 online resource (298 p.) |
| Disciplina |
591.8/7
591.87 |
| Altri autori (Persone) |
WolstenholmeG. E. W (Gordon Ethelbert Ward)
KnightJulie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Tissue culture
Virology - Cultures and culture media |
| ISBN |
1-280-76847-9
9786613679246 0-470-71981-8 0-470-71746-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GROWTH CONTROL IN CELL CULTURES; Contents; Chairman's introduction; Studies of serum factors required by 3T3 and SV3T3 cells; Discussion; Conditions affecting the response of cultured cells to serum; Discussion; Factors controlling the multiplication of untransformed and transformed BHK2l cells under various environmental conditions; Discussion; The significance of surface structure changes for growth control under crowded conditions; Discussion; Regulation of cell multiplication in tissue culture; Discussion; Molecular exchange and growth control in tissue culture; Discussion
Attempts to isolate SV40 transformation factorDiscussion; Growth regulation in cultures of chick embryo fibroblasts; Discussion; SV40 transformation and cellular growth control; Discussion; Growth control between dissimilar cells in culture; Discussion; Specific growth regulation in early subcultures of human diploid fibroblasts; Discussion; Transport and phospholipid changes related to control of growth in 3T3 cells; Discussion; Aspects of membrane structure and function in Escherichia coli; Discussion; General Discussion; Chairman's closing remarks Appendix: growth properties of normal and trans- formed cellsAuthor index; Subject index |
| Record Nr. | UNINA-9910643849703321 |
| London, : Churchill Livingstone, 1971 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Growth control in cell cultures [[electronic resource] ] : a Ciba Foundation Symposium / / edited by G.E.W. Wolstenholme and Julie Knight
| Growth control in cell cultures [[electronic resource] ] : a Ciba Foundation Symposium / / edited by G.E.W. Wolstenholme and Julie Knight |
| Pubbl/distr/stampa | London, : Churchill Livingstone, 1971 |
| Descrizione fisica | 1 online resource (298 p.) |
| Disciplina |
591.8/7
591.87 |
| Altri autori (Persone) |
WolstenholmeG. E. W (Gordon Ethelbert Ward)
KnightJulie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Tissue culture
Virology - Cultures and culture media |
| ISBN |
1-280-76847-9
9786613679246 0-470-71981-8 0-470-71746-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GROWTH CONTROL IN CELL CULTURES; Contents; Chairman's introduction; Studies of serum factors required by 3T3 and SV3T3 cells; Discussion; Conditions affecting the response of cultured cells to serum; Discussion; Factors controlling the multiplication of untransformed and transformed BHK2l cells under various environmental conditions; Discussion; The significance of surface structure changes for growth control under crowded conditions; Discussion; Regulation of cell multiplication in tissue culture; Discussion; Molecular exchange and growth control in tissue culture; Discussion
Attempts to isolate SV40 transformation factorDiscussion; Growth regulation in cultures of chick embryo fibroblasts; Discussion; SV40 transformation and cellular growth control; Discussion; Growth control between dissimilar cells in culture; Discussion; Specific growth regulation in early subcultures of human diploid fibroblasts; Discussion; Transport and phospholipid changes related to control of growth in 3T3 cells; Discussion; Aspects of membrane structure and function in Escherichia coli; Discussion; General Discussion; Chairman's closing remarks Appendix: growth properties of normal and trans- formed cellsAuthor index; Subject index |
| Record Nr. | UNISA-996199373503316 |
| London, : Churchill Livingstone, 1971 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Growth control in cell cultures [[electronic resource] ] : a Ciba Foundation Symposium / / edited by G.E.W. Wolstenholme and Julie Knight
| Growth control in cell cultures [[electronic resource] ] : a Ciba Foundation Symposium / / edited by G.E.W. Wolstenholme and Julie Knight |
| Pubbl/distr/stampa | London, : Churchill Livingstone, 1971 |
| Descrizione fisica | 1 online resource (298 p.) |
| Disciplina |
591.8/7
591.87 |
| Altri autori (Persone) |
WolstenholmeG. E. W (Gordon Ethelbert Ward)
KnightJulie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Tissue culture
Virology - Cultures and culture media |
| ISBN |
1-280-76847-9
9786613679246 0-470-71981-8 0-470-71746-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GROWTH CONTROL IN CELL CULTURES; Contents; Chairman's introduction; Studies of serum factors required by 3T3 and SV3T3 cells; Discussion; Conditions affecting the response of cultured cells to serum; Discussion; Factors controlling the multiplication of untransformed and transformed BHK2l cells under various environmental conditions; Discussion; The significance of surface structure changes for growth control under crowded conditions; Discussion; Regulation of cell multiplication in tissue culture; Discussion; Molecular exchange and growth control in tissue culture; Discussion
Attempts to isolate SV40 transformation factorDiscussion; Growth regulation in cultures of chick embryo fibroblasts; Discussion; SV40 transformation and cellular growth control; Discussion; Growth control between dissimilar cells in culture; Discussion; Specific growth regulation in early subcultures of human diploid fibroblasts; Discussion; Transport and phospholipid changes related to control of growth in 3T3 cells; Discussion; Aspects of membrane structure and function in Escherichia coli; Discussion; General Discussion; Chairman's closing remarks Appendix: growth properties of normal and trans- formed cellsAuthor index; Subject index |
| Record Nr. | UNINA-9910830270603321 |
| London, : Churchill Livingstone, 1971 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Growth control in cell cultures : a Ciba Foundation Symposium / / edited by G.E.W. Wolstenholme and Julie Knight
| Growth control in cell cultures : a Ciba Foundation Symposium / / edited by G.E.W. Wolstenholme and Julie Knight |
| Pubbl/distr/stampa | London, : Churchill Livingstone, 1971 |
| Descrizione fisica | 1 online resource (298 p.) |
| Disciplina | 591.8/7 |
| Altri autori (Persone) |
WolstenholmeG. E. W (Gordon Ethelbert Ward)
KnightJulie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Tissue culture
Virology - Cultures and culture media |
| ISBN |
9786613679246
9781280768477 1280768479 9780470719817 0470719818 9780470717462 0470717467 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GROWTH CONTROL IN CELL CULTURES; Contents; Chairman's introduction; Studies of serum factors required by 3T3 and SV3T3 cells; Discussion; Conditions affecting the response of cultured cells to serum; Discussion; Factors controlling the multiplication of untransformed and transformed BHK2l cells under various environmental conditions; Discussion; The significance of surface structure changes for growth control under crowded conditions; Discussion; Regulation of cell multiplication in tissue culture; Discussion; Molecular exchange and growth control in tissue culture; Discussion
Attempts to isolate SV40 transformation factorDiscussion; Growth regulation in cultures of chick embryo fibroblasts; Discussion; SV40 transformation and cellular growth control; Discussion; Growth control between dissimilar cells in culture; Discussion; Specific growth regulation in early subcultures of human diploid fibroblasts; Discussion; Transport and phospholipid changes related to control of growth in 3T3 cells; Discussion; Aspects of membrane structure and function in Escherichia coli; Discussion; General Discussion; Chairman's closing remarks Appendix: growth properties of normal and trans- formed cellsAuthor index; Subject index |
| Record Nr. | UNINA-9911019345803321 |
| London, : Churchill Livingstone, 1971 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Live variola virus [[electronic resource] ] : considerations for continuing research / / Committee on the Assessment of Future Scientific Needs for Live Variola Virus; Board on Global Health ; Ann M. Arvin and Deepali M. Patel, editors ; Institute of Medicine of the National Academies
| Live variola virus [[electronic resource] ] : considerations for continuing research / / Committee on the Assessment of Future Scientific Needs for Live Variola Virus; Board on Global Health ; Ann M. Arvin and Deepali M. Patel, editors ; Institute of Medicine of the National Academies |
| Pubbl/distr/stampa | Washington, D.C., : National Academies Press, 2009 |
| Descrizione fisica | 1 online resource (170 p.) |
| Disciplina | 616.912 |
| Altri autori (Persone) |
ArvinAnn M
PatelDeepali |
| Soggetto topico |
Smallpox - Research
Smallpox - Prevention Smallpox vaccine Virology - Cultures and culture media |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-41256-6
9786612412561 0-309-13691-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | ""Reviewers""; ""Preface""; ""Acknowledgments""; ""Contents""; ""Summary""; ""1 Introduction""; ""2 Overview of Smallpox and Its Surveillance and Control""; ""3 Comparative Poxvirology""; ""4 Animal Models Using Variola and Other Orthopoxviruses""; ""5 Genomic Analysis""; ""6 Development of Therapeutics""; ""7 Development of Vaccines""; ""8 Methods for Detection and Diagnosis""; ""9 Discovery Research""; ""10 Conclusions and Recommendations""; ""Appendix: Variola Strains Used to Validate Diagnostic and Detection Assays"" |
| Record Nr. | UNINA-9910456142503321 |
| Washington, D.C., : National Academies Press, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Live variola virus [[electronic resource] ] : considerations for continuing research / / Committee on the Assessment of Future Scientific Needs for Live Variola Virus; Board on Global Health ; Ann M. Arvin and Deepali M. Patel, editors ; Institute of Medicine of the National Academies
| Live variola virus [[electronic resource] ] : considerations for continuing research / / Committee on the Assessment of Future Scientific Needs for Live Variola Virus; Board on Global Health ; Ann M. Arvin and Deepali M. Patel, editors ; Institute of Medicine of the National Academies |
| Pubbl/distr/stampa | Washington, D.C., : National Academies Press, 2009 |
| Descrizione fisica | 1 online resource (170 p.) |
| Disciplina | 616.912 |
| Altri autori (Persone) |
ArvinAnn M
PatelDeepali |
| Soggetto topico |
Smallpox - Research
Smallpox - Prevention Smallpox vaccine Virology - Cultures and culture media |
| ISBN |
1-282-41256-6
9786612412561 0-309-13691-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | ""Reviewers""; ""Preface""; ""Acknowledgments""; ""Contents""; ""Summary""; ""1 Introduction""; ""2 Overview of Smallpox and Its Surveillance and Control""; ""3 Comparative Poxvirology""; ""4 Animal Models Using Variola and Other Orthopoxviruses""; ""5 Genomic Analysis""; ""6 Development of Therapeutics""; ""7 Development of Vaccines""; ""8 Methods for Detection and Diagnosis""; ""9 Discovery Research""; ""10 Conclusions and Recommendations""; ""Appendix: Variola Strains Used to Validate Diagnostic and Detection Assays"" |
| Record Nr. | UNINA-9910780434203321 |
| Washington, D.C., : National Academies Press, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
