Pubbl/distr/stampa	Hauppauge, NY, : Nova Science Publishers, Inc., 2012
Descrizione fisica	1 online resource (211 p.)
Collana	Immunology and immune system disorders
Soggetto topico	Graft rejection Transplantation immunology
Soggetto genere / forma	Electronic books.
ISBN	1-61942-351-0
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	""ACUTE REJECTION: RISK FACTORS, MANAGEMENT AND COMPLICATIONS""; ""ACUTE REJECTION: RISK FACTORS, MANAGEMENT AND COMPLICATIONS""; ""Library of Congress Cataloging-in-Publication Data""; ""Contents""; ""Preface""; ""Chapter 1: HLA and Non-HLA Genes Polymorphisms: Susceptibility and Severity in Tunisian Patients with Rheumatoid Arthritis""; ""Abstract""; ""1. Introduction""; ""2. Evaluation of Genetic Predisposition to RA""; ""2.1. Prevalence of RA""; ""2.2. Familial Clustering Studies""; ""2.3. Twins Studies""; ""3. Identification of Candidate Genes""; ""3.1. Linkage Studies"" ""3.2. Candidate Gene Association Studies""""4. Results of Linkage Studies in RA""; ""5. HLA Association With RA""; ""6. Non HLA Candidate Genes Case-control Studies""; ""6.1. Protein Tyrosine Phosphatase Non-Receptor, Type 22 (PTPN22)""; ""6.2. Tumor Necrosis Factor Receptor Type 2 (TNF-R2)""; ""6.3. Peptidyl Arginine Deiminase 4 (PADI 4)""; ""6.4. Fc Î³ Receptor IIIa (FcÎ³RIIIa)""; ""6.5. Interleukin 1 Receptor Antagonist (IL-1Ra)""; ""6.6. Cytotoxic T Lymphocyte-Associated Antigen-4 (CTLA-4)""; ""6.7. Apo-1/Fas (CD95)""; ""6.8. Adhesion Molecules""; ""7. Patients and Methods"" ""7.1. Patients and Controls""""7.2. Methods""; ""7.3. Statistical Methods""; ""8. Results""; ""8.1. HLA Typing""; ""a/ DRB1 Genotyping""; ""b/ DRB1*04 Sub-typing""; ""8.2. PTPN22 Genotyping""; ""8.3. CTLA-4 Genotyping""; ""8.4. Apo-1/Fas Genotyping""; ""8.5. FcÎ³R Genotyping""; ""8.6. Adhesion Molecules Genotyping""; ""8.7. IL1 Family Polymorphisms Genotyping""; ""a/ IL1Î± (C/T -889)""; ""b/ IL1Ra (Intron 2)""; ""c/ IL1Î² C/T -511 and C/T +3954""; ""9. Discussion""; ""Conclusion""; ""Acknowledgment""; ""References"" ""Chapter 2: Mechanisms, Management and Consequences of Acute Cellular and Antibody Mediated Rejection in Solid Organ and Reconstructive Transplantation""""Abstract""; ""1. Acute Rejection""; ""2. Kidney Transplantation""; ""2.1 The Banff Classification""; ""2.2 Acute Antibody-Mediated Rejection in Kidney Transplantation""; ""2.3 Acute T-Cell-Mediated Rejection in Kidney Transplantation""; ""2.3.1. Steps in TCMR â€? 3 Signals [12]""; ""3. Pancreas Transplantation""; ""3.1 The Banff Classification""; ""3.2 Acute Antibody-Mediated Rejection in Pancreas Transplantation"" ""3.3 Acute T-Cell-Mediated Rejection in Pancreas Transplantation""""4. Liver Transplantation""; ""4.1 Banff Schema for Grading of Liver Allograft Rejection""; ""4.2 Acute Antibody-Mediated Rejection in Liver Transplantation""; ""4.3 Acute T-Cell-Mediated Rejection in Liver Transplantation""; ""5. Intestinal and Multivisceral Transplantation""; ""5.2 Acute Antibody-Mediated Rejection in Intestinal Transplantation""; ""5.3 Acute T-Cell-Mediated Rejection in Intestinal Transplantation""; ""6. Vascularized Composite Allotransplantation"" ""6.1 Banff Classification of Skin-Containing Composite Tissue Allografts""
Record Nr.	UNINA-9910452895703321

Pubbl/distr/stampa	Amsterdam : , : Elsevier, , 1973
Descrizione fisica	1 online resource (374 pages)
Disciplina	617.7/19
Collana	Ciba Foundation symposium (new series)
Soggetto topico	Cornea - Transplantation Transplantation immunology
ISBN	1-280-78324-9 9786613693631 0-470-71998-2 0-470-71765-3
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Corneal Graft Failure; Contents; Introduction to the problems of corneal graft failure; Clinical patterns of corneal graft failure; Discussion; Pathophysiology of graft failure; Discussion; The quality of donor corneas for penetrating keratoplasty; Discussion; Problems of cell survival after freezing and thawing with special reference to the cornea; Discussion; Immunologically privileged sites and tissues; Discussion; Transplantation immunobiology of the cornea; Discussion; Corneal graft rejection : clinico-pathological correlation; Discussion The allograft rejection reaction: the leading cause of late failure of clinical corneal grafts Discussion; Recurrence of host disease in the graft; Discussion; The role of corneal vascularization in human corneal graft reactions; Discussion; The role of surgical factors in corneal graft failure; Discussion; Problems of corneal grafting in herpetic keratitis; Discussion; The role of steroids in the prevention of corneal graft failure; Discussion; The biological basis of immunosuppression; Discussion; Some clinical problems of immunosuppression; Discussion The influence of HL-A conipatibility on the fate of corneal grafts Discussion; Influence of histocompatibility on the fate of the corneal transplant; Discussion; Difficulties in the use of tissue typing for corneal grafting; Discussion; General Discussion : The successful corneal graft; Criteria for diagnosis of a corneal allograft reaction; Summing up - Present knowledge and problems of corneal graft failure; Index of contributors; Subject index
Record Nr.	UNISA-996202086503316

Pubbl/distr/stampa	Cham, Switzerland : , : Springer, , [2021]
Descrizione fisica	1 online resource (1737 pages)
Disciplina	617.954
Soggetto topico	Transplantation of organs, tissues, etc - Complications Transplantation immunology Infection Transplantation Immunology Infections Trasplantament d'òrgans Infeccions quirúrgiques Immunologia de la trasplantació
Soggetto genere / forma	Llibres electrònics
ISBN	3-030-25869-6
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Intro -- Preface -- Contents -- About the Editors -- Contributors -- Part I: General Introduction -- 1 Impact of Infection on Transplant Outcomes: Transplant Infectious Disease Expertise as an Essential Component of Transplant ... -- Introduction -- The Essential Role of Infectious Disease Specialists in the Care of Transplant Patients -- Conclusion -- References -- 2 Introduction to Immunosuppression, Tolerance, and Infection Risk -- Introduction -- T-Cell, B-Cells, and the Innate Immune System Involvement in Rejection -- Other Elements of the Immune System Involved in Transplantation -- Therapeutics Impacting Immunosuppression -- Calcineurin Inhibitors -- Antiproliferative Agents -- mTOR Inhibitors -- Corticosteroids -- Co-stimulation Blockade -- Induction Therapies -- Anti-CD25 Monoclonal Antibodies -- Anti-CD52 Monoclonal Antibodies -- Polyclonal Antibodies -- Conclusion -- Key Points -- References -- 3 Changing Definition of Immunosuppression: Targeted Therapies and Resulting Emerging Infections and Their Prevention -- Introduction -- Belatacept -- Key Findings and Suggestions -- Basiliximab -- Key Findings and Suggestions -- Rituximab and Obinutuzumab -- Key Findings and Suggestions -- Alemtuzumab -- Key Findings and Suggestions -- Eculizumab -- Key Findings and Suggestions -- Ruxolitinib -- Key Findings and Suggestions -- Ibrutinib -- Key Findings and Suggestions -- Bortezomib -- Key Findings and Suggestions -- Brentuximab -- Key Findings and Suggestions -- Conclusions -- References -- 4 Stem Cell Transplantation: Infection Risk by Transplant Type and Emerging Trends in Infection Management -- Introduction -- Risk of Infection Post-HSCT -- General Immune Reconstitution After Hematopoietic Stem Cell Transplantation -- Aplastic Period -- NK Cells and T-Cells -- B-Cells and Immunoglobulins -- Graft-Versus-Host Disease. Special Donor Populations -- Umbilical Cord Blood Transplantation -- Haploidentical Transplantation -- Pre-HSCT Recipient Infectious Disease Evaluation -- Prophylaxis and Management of Infection Post-HSCT -- Bacterial Infections -- Bloodstream Infections -- Diagnosis -- Management -- Gram-Positive Bacterial Infections -- Multidrug-Resistant Gram-Negative Bacterial Infections -- Bacterial Pneumonia -- Clostridioides Difficile -- Diagnosis -- Management -- Recurrent CDI -- Secondary Prophylaxis -- Fungal Infections -- Yeasts -- Disease Epidemiology -- Candida auris -- Diagnosis -- Blood Cultures -- Fungal Antigen Testing: Serum 1,3-Beta-D-Glucan -- Nanodiagnostics -- Candida auris-Specific Diagnostics -- Management -- Candida Species -- Candida auris -- Cryptococcus -- Molds -- Disease Epidemiology -- Clinical Impact -- Diagnosis -- Culture -- Galactomannan -- Aspergillus PCR -- Radiographic Studies -- Fungal Metabolite Testing -- Management -- Prophylaxis -- Treatment -- Pneumocystis Jiroveci -- Viral Infections -- Herpes Simplex Virus -- Varicella Zoster -- Cytomegalovirus -- Diagnosis -- Preemptive Management -- Prophylaxis: Shift in Management -- Drug-Resistant CMV Infection -- Epstein-Barr Virus -- Adenovirus -- BK Virus -- Parasitic Infections -- Toxoplasmosis -- Strongyloides -- Post-HSCT Vaccinations -- Conclusions -- Key Points -- Cross-References -- References -- 5 Evolving Epidemiology of Transplant Infections: Impact of Population Shifts and Climate Change -- Introduction -- Migration and Population Shift -- Modern Patterns of Human Migration and Infection -- Shifting Populations and the Changing Epidemiology of Infectious Diseases -- Preventative Strategies and Global Demographic Changes -- Climate Change and Infectious Diseases -- Climate Change and Parasitic Infections -- Climate Change and Vector-Borne Infections. Climate Change and Fungal Infections -- Climate Change and Bacterial Infections -- Conclusion -- Key Points -- References -- 6 Hospital Epidemiology and Infection Control in the Transplant Center -- Introduction -- Hand Hygiene -- Central Line-Associated Bloodstream Infections -- Catheter-Associated Urinary Tract Infections -- Clostridioides difficile -- Surgical Site Infections -- Preventing Infections Associated with the Healthcare Environment -- Environmental Mold -- Waterborne Pathogens -- Colonization with Multidrug-Resistant Organisms -- Respiratory Viruses -- Influenza -- Respiratory Syncytial Virus -- Adenovirus -- Other Respiratory Viruses -- Varicella-Zoster Virus -- Measles -- Healthcare Personnel Vaccination -- Conclusion -- Key Points -- Cross-References -- References -- 7 Antimicrobial Stewardship for Transplant Candidates and Recipients -- Introduction -- Implementing Antimicrobial Stewardship in Transplant Patients -- Formulary Management -- Pre-prescription Authorization and Post-prescriptive Review -- Antimicrobial Agent Selection -- Antibiotic Allergy Assessment -- Dose Optimization and Drug Interactions -- Intravenous-to-Oral Conversion -- Clinical Pathways and Guideline Development -- Diagnostic Test Stewardship -- Syndrome- and Drug-Specific Targets -- Antibiotic Stewardship -- Febrile Neutropenia -- Asymptomatic Bacteriuria in Organ Transplant Recipients -- Antiviral Stewardship -- Aerosolized Ribavirin for Management of RSV -- Cytomegalovirus (CMV) -- Antifungal Stewardship -- Antimicrobial Stewardship Program Metrics -- Conclusion -- Key Points -- References -- 8 Antimicrobial Prophylaxis in the Age of Emerging Transplant Infections -- Introduction -- Perioperative Antibacterial Prophylaxis in Solid Organ Transplantation -- Antibiotic Prophylaxis After Transplantation -- Antifungal Prophylaxis After Transplantation. Mycobacterial Prophylaxis After Transplantation -- Influenza Prophylaxis After Transplantation -- Herpes Simplex Virus and Varicella Zoster Virus Prophylaxis After Transplantation -- Cytomegalovirus Prophylaxis After Transplantation -- BK Polyomavirus Prophylaxis After Transplantation -- Parasitic Prophylaxis in Transplantation -- Conclusion -- Key Points -- References -- 9 Pretransplant Screening for Infection Exposure: Approach to the Patients with Epidemiologic and Geographic Risk Factors -- Introduction -- Bacterial Infections -- Bacterial Pathogens of Special Interest -- Mycobacterial Infections -- Tuberculosis -- Nontuberculous Mycobacteria -- M. abscessus -- Non-M. abscessus Non-M. tuberculosis Mycobacterial Infections -- Fungi -- Endemic Fungal Infections -- Histoplasmosis -- Blastomycosis -- Paracoccidioidomycosis -- Coccidioidomycosis -- Cryptococcosis -- Aspergillus and Other Molds -- Parasitic Infections -- Chagas Disease -- Schistosomiasis -- Strongyloidiasis -- Leishmaniasis -- Malaria -- Toxoplasmosis -- Viral Infections in the Transplant Candidate -- Blood-borne Pathogens -- Endemic Human Herpes Viruses -- Viral Infections with Geographic Associations -- Human Herpesvirus-8 (HHV-8) -- HTLV-1 -- Flaviviruses (Arboviruses) -- West Nile Virus (WNV) -- Zika, Chikungunya, and Dengue Viruses -- Conclusion -- KeyPoints -- References -- 10 Transplant Tourism and the Traveling Transplant Recipient: Infection Mitigation and Treatment Strategies -- Introduction -- Part 1: Transplant Tourism -- Introduction -- Transplant Tourism and Infectious Complications -- Conclusion -- Key Points -- Part 2: The Traveling Transplant Recipient -- Introduction -- Risk of Infection While Abroad -- Viral Infections -- Respiratory Viral Infections -- Influenza -- Measles -- Middle Eastern Respiratory Syndrome -- Gastrointestinal Viral Infections -- Norovirus. Hepatitis A -- Hepatitis B -- Hepatitis E -- Polio -- Vector-Borne Viral Infections -- Yellow Fever -- Japanese Encephalitis -- Dengue, Chikungunya, and Zika -- Rabies -- Bacterial Infections -- Salmonella enterica Serovar Typhi -- Vibrio cholerae -- Enterotoxigenic Escherichia coli (ETEC) -- Neisseria meningitidis -- Streptococcus pneumoniae -- Clostridium tetani -- Corynebacterium diphtheriae -- Bordetella pertussis -- Mycobacterial Infections -- Mycobacterium tuberculosis -- Fungal Infections -- Parasitic Infections -- Vector-Borne Parasite Infections -- Plasmodium Species -- Leishmania Species -- Trypanosoma Species -- Babesia Species -- Environmentally Transmitted Parasite Infections -- Strongyloides stercoralis -- Schistosoma Species -- Ingested Parasitic Infections -- Pre-departure Infectious Disease Evaluation and Recommendations -- Vaccine Recommendations -- Risk Reduction of Non-vaccine-Preventable Infections -- Prevention of Food-Borne Illnesses and Diarrhea -- Respiratory Infections -- Insect Protection -- Environmental Exposures -- Blood-Borne Pathogens -- Sexually Transmitted Infections (STI) -- Post-travel Evaluation -- Conclusion -- Key Points -- References -- 11 Preventative Health in Solid Organ Transplant: Safe Living Post-transplant -- Introduction -- Pre-transplant Evaluation -- Vaccination -- Everyday Living Strategies -- Activities of Leisure -- Sexual Health -- Food and Water Safety -- Animal and Insect Precautions -- Travel Advice -- Conclusion -- Key Points -- References -- 12 Vaccination Strategies in Solid Organ and Stem Cell Transplant -- Introduction to Vaccination in Transplant Recipients -- Specific Vaccine Recommendations -- Vaccination Against Influenza -- Vaccination Against Pneumococcal Disease -- Vaccination Against Meningococcal Disease -- Vaccination Against Hepatitis B Virus. Vaccination Against Hepatitis A Virus.
Record Nr.	UNINA-9910485605403321

Pubbl/distr/stampa	Georgetown, Tex., : Landes Bioscience, ©1998-2003
Disciplina	617.95
Soggetto topico	Transplantation of organs, tissues, etc Cell transplantation Transplantation immunology Graft rejection Bone marrow - Transplantation Organ Transplantation Bone Marrow Transplantation Cell Transplantation Graft Rejection Transplantation Immunology Greffe (Chirurgie) Cellules - Greffe Greffe (Chirurgie) - Immunologie Rejet (Biologie) Moelle osseuse - Greffe
Soggetto genere / forma	Periodicals.
ISSN	2160-0066
Formato	Materiale a stampa
Livello bibliografico	Periodico
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910133981803321

Pubbl/distr/stampa	West Sussex, : John Wiley, 2012
Descrizione fisica	1 online resource (485 p.)
Disciplina	615.37
Altri autori (Persone)	KaplanBruce <1958-> BurckartGilbert J LakkisFadi G
Soggetto topico	Immunotherapy Transplantation immunology
ISBN	1-280-58641-9 9786613616241 1-4443-5562-7 1-4443-5543-0
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Immunotherapy in Transplantation: Principles and Practice; Contents; List of Contributors; Preface; Part 1 Transplantation Immunobiology; 1 The Immune Response to a Transplanted Organ: An Overview; 2 Antigen Presentation in Transplantation; 3 The T Cell Response to Transplantation Antigens; 4 The B Cell Response to Transplantation Antigens; 5 The Innate Response to a Transplanted Organ; 6 Regulation of the Alloimmune Response; Part 2 Transplantation Clinical Pharmacology; 7 Pharmacokinetics; 8 Therapeutic Drug Monitoring for Immunosuppressive Agents 9 Pharmacometrics: Concepts and Applications to Drug Development10 Pharmacogenomics and Organ Transplantation; 11 Study Design/Process of Development: Clinical Studies; Part 3 Agents; 12 Corticosteroids; 13 Azathioprine; 14 Pharmacokinetic and Pharmacodynamic Properties of Mycophenolate; 15 Cyclosporine: Molecular Action to Clinical Therapeutics; 16 Tacrolimus; 17 Inhibitors of Mammalian Target of Rapamycin; 18 Inhibitors Targeting JAK3; 19 Cyclophosphamide; 20 Application of Antisense Technology in Medicine; 21 The Role of Ganciclovir in Transplantation 22 Transplantation Immunotherapy with Antithymocyte Globulin (ATG)23 The Role of Alemtuzumab in Solid Organ Transplantation; 24 Rituximab, an Anti-CD20 Monoclonal Antibody; 25 The Anti-Interleukin 2 Receptor Antibodies; 26 Infliximab/Anti-TNF; 27 CTLA4-Ig; 28 Combination and Adjuvant Therapies to Facilitate the Efficacy of Costimulatory Blockade; 29 Intravenous Immunoglobulin (IVIG) a Modulator of Immunity and Inflammation with Applications in Solid Organ Transplantation; Index; Color Plates
Record Nr.	UNINA-9910141335403321