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Application of modern toxicology approaches for predicting acute toxicity for chemical defense / / Committee on Predictive-Toxicology Approaches for Military Assessments of Acute Exposures [and four others]
| Application of modern toxicology approaches for predicting acute toxicity for chemical defense / / Committee on Predictive-Toxicology Approaches for Military Assessments of Acute Exposures [and four others] |
| Pubbl/distr/stampa | Washington, District of Columbia : , : The National Academies Press, , 2015 |
| Descrizione fisica | 1 online resource (134 p.) |
| Disciplina | 355.3440973 |
| Soggetto topico |
Chemical warfare - United States - Safety measures
Toxicology - Research - United States |
| Soggetto genere / forma | Electronic books. |
| ISBN | 0-309-37667-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | FrontMatter; Preface; Contents; Application of Modern Toxicology Approaches for Predicting Acute Toxicity for Chemical Defense; Summary; 1 Introduction; 2 Conceptual Framework and Prioritization Strategy; 3 Nontesting Approaches Relevant to Prediction of Acute Toxicity and Potency; 4 Assays for Predicting Acute Toxicity; 5 Integration and Decision-Making for Predictive Toxicology; 6 Lessons Learned and Next Steps; Appendix A: Biographical Information on the Committee on Predictive-Toxicology Approaches for Military Assessments of Acute Exposures; Appendix B: Available Data or Databases |
| Record Nr. | UNINA-9910461680903321 |
| Washington, District of Columbia : , : The National Academies Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Application of modern toxicology approaches for predicting acute toxicity for chemical defense / / Committee on Predictive-Toxicology Approaches for Military Assessments of Acute Exposures [and four others]
| Application of modern toxicology approaches for predicting acute toxicity for chemical defense / / Committee on Predictive-Toxicology Approaches for Military Assessments of Acute Exposures [and four others] |
| Pubbl/distr/stampa | Washington, District of Columbia : , : The National Academies Press, , 2015 |
| Descrizione fisica | 1 online resource (134 p.) |
| Disciplina | 355.3440973 |
| Soggetto topico |
Chemical warfare - United States - Safety measures
Toxicology - Research - United States |
| ISBN | 0-309-37667-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | FrontMatter; Preface; Contents; Application of Modern Toxicology Approaches for Predicting Acute Toxicity for Chemical Defense; Summary; 1 Introduction; 2 Conceptual Framework and Prioritization Strategy; 3 Nontesting Approaches Relevant to Prediction of Acute Toxicity and Potency; 4 Assays for Predicting Acute Toxicity; 5 Integration and Decision-Making for Predictive Toxicology; 6 Lessons Learned and Next Steps; Appendix A: Biographical Information on the Committee on Predictive-Toxicology Approaches for Military Assessments of Acute Exposures; Appendix B: Available Data or Databases |
| Record Nr. | UNINA-9910797529103321 |
| Washington, District of Columbia : , : The National Academies Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Application of modern toxicology approaches for predicting acute toxicity for chemical defense / / Committee on Predictive-Toxicology Approaches for Military Assessments of Acute Exposures [and four others]
| Application of modern toxicology approaches for predicting acute toxicity for chemical defense / / Committee on Predictive-Toxicology Approaches for Military Assessments of Acute Exposures [and four others] |
| Pubbl/distr/stampa | Washington, District of Columbia : , : The National Academies Press, , 2015 |
| Descrizione fisica | 1 online resource (134 p.) |
| Disciplina | 355.3440973 |
| Soggetto topico |
Chemical warfare - United States - Safety measures
Toxicology - Research - United States |
| ISBN | 0-309-37667-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | FrontMatter; Preface; Contents; Application of Modern Toxicology Approaches for Predicting Acute Toxicity for Chemical Defense; Summary; 1 Introduction; 2 Conceptual Framework and Prioritization Strategy; 3 Nontesting Approaches Relevant to Prediction of Acute Toxicity and Potency; 4 Assays for Predicting Acute Toxicity; 5 Integration and Decision-Making for Predictive Toxicology; 6 Lessons Learned and Next Steps; Appendix A: Biographical Information on the Committee on Predictive-Toxicology Approaches for Military Assessments of Acute Exposures; Appendix B: Available Data or Databases |
| Record Nr. | UNINA-9910823549203321 |
| Washington, District of Columbia : , : The National Academies Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
NCTR quarter page [[electronic resource] /] / Division of Planning
| NCTR quarter page [[electronic resource] /] / Division of Planning |
| Pubbl/distr/stampa | Jefferson, Ark., : DDHS/FDA/NCTR |
| Descrizione fisica | electronic text, volumes : HTML, digital, PDF file |
| Soggetto topico | Toxicology - Research - United States |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | National Center for Toxicological Research quarter page |
| Record Nr. | UNINA-9910695795003321 |
| Jefferson, Ark., : DDHS/FDA/NCTR | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
NTP liaison office news [[electronic resource]]
| NTP liaison office news [[electronic resource]] |
| Pubbl/distr/stampa | Research Triangle Park, NC, : National Toxicology Program, [1994-1998] |
| Descrizione fisica | : HTML file |
| Soggetto topico | Toxicology - Research - United States |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | National Toxicology Program liaison office news |
| Record Nr. | UNINA-9910698218803321 |
| Research Triangle Park, NC, : National Toxicology Program, [1994-1998] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
NTP update [[electronic resource]]
| NTP update [[electronic resource]] |
| Pubbl/distr/stampa | Research Triangle Park, NC, : National Toxicology Program, 1999-2003 |
| Descrizione fisica | volumes : digital, PDF file |
| Soggetto topico | Toxicology - Research - United States |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
National Toxicology Program update
NTP liaison office news |
| Record Nr. | UNINA-9910698218703321 |
| Research Triangle Park, NC, : National Toxicology Program, 1999-2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Spacecraft maximum allowable concentrations for selected airborne contaminants . Volume 1 [[electronic resource] /] / Subcommittee on Spacecraft Maximum Allowable Concentrations, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
| Spacecraft maximum allowable concentrations for selected airborne contaminants . Volume 1 [[electronic resource] /] / Subcommittee on Spacecraft Maximum Allowable Concentrations, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1994 |
| Descrizione fisica | 1 online resource (235 p.) |
| Disciplina | 629.477 |
| Soggetto topico |
Space cabin atmospheres
Space vehicles - Air pollution Space vehicles - Air quality - Standards Space vehicles - Contamination Space vehicles - Environmental aspects Toxicology - Research - United States |
| Soggetto genere / forma | Electronic books. |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants""; ""Copyright""; ""Preface""; ""Contents""; ""Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants""; ""INTRODUCTION""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING SMACS""; ""REVIEW OF SMAC REPORTS""; ""REFERENCES""; ""Appendix A Executive Summary of Guidelines for Developing Spacecraft Maximum Allowable Concentration for Space Station�""; ""EXECUTIVE SUMMARY: SPACECRAFT MAXIMUM ALLOWABLE CONCENTRATIONS FOR SPACE STATION CONTAMINANTS""
""ENVIRONMENTAL CONTROL AND LIFE-SUPPORT SYSTEM""""MODIFICATION OF CONTAMINANT TOXICITY BY ENVIRONMENTAL FACTORS""; ""SOURCES AND TYPES OF DATA FOR ESTABLISHMENT OF SMACS""; ""Chemical-Physical Characteristics of Toxicants""; ""In Vitro Toxicity Studies""; ""Animal Toxicity Studies""; ""Clinical and Epidemiological Observations""; ""Pharmacokinetics and Metabolism""; ""Biological Markers""; ""RISK ASSESSMENT (DEVELOPMENT OF EXPOSURE CRITERIA)""; ""ISSUES IN MAKING RECOMMENDATIONS FOR THE ESTABLISHMENT OF SMACS"" ""Appendix B Reports on Spacecraft Maximum Allowable Concentrations (SMACs) for Selected Airborne Contaminants""""B1 ACETALDEHYDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Acute Toxicity""; ""Mucosal Irritation""; ""Miscellaneous Mucosal Effects""; ""Lethality""; ""Subchronic and Chronic Toxicity""; ""Nasal Toxicity""; ""Pulmonary and Renal Toxicity""; ""Carcinogenicity""; ""Genotoxicity""; ""Reproductive and Developmental Toxicity""; ""Synergistic Effects""; ""RATIONALE""; ""Carcinogenicity"" ""Mucosal Irritation""""The Establishment of SMACs""; ""REFERENCES""; ""B2 AMMONIA""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Mechanisms of Tissue Injuries""; ""Mucosal Irritation in Naive Subjects""; ""Mucosal Irritation in Adapted Subjects""; ""Mucosal Irritation in Subjects Of Unknown Adaptation Status""; ""Toxic Effects of Massive Exposures""; ""Animal Models of Ammonia's Respiratory Damage""; ""Metabolic Acidosis""; ""RATIONALE""; ""1-h SMAC and 24-h SMAC""; ""7-d SMAC""; ""30-d SMAC and 180-d SMAC"" ""REFERENCES""""B3 CARBON MONOXIDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS""; ""TOXICITY SUMMARY""; ""Acute Toxicity""; ""Adaptation""; ""Subchronic and Chronic Toxicity""; ""Synergistic Effects""; ""RATIONALE""; ""1-h SMAC""; ""24-h SMAC""; ""7-d SMAC""; ""30-d SMAC and 180-d SMAC""; ""1-h and 24-h SMACs Immediately Following CO Exposure""; ""REFERENCES""; ""B4 FORMALDEHYDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Acute Toxicity"" ""Subchronic and Chronic Toxicity"" |
| Record Nr. | UNINA-9910451820503321 |
| Washington, D.C., : National Academy Press, 1994 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Spacecraft maximum allowable concentrations for selected airborne contaminants . Volume 1 [[electronic resource] /] / Subcommittee on Spacecraft Maximum Allowable Concentrations, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
| Spacecraft maximum allowable concentrations for selected airborne contaminants . Volume 1 [[electronic resource] /] / Subcommittee on Spacecraft Maximum Allowable Concentrations, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1994 |
| Descrizione fisica | 1 online resource (235 p.) |
| Disciplina | 629.477 |
| Soggetto topico |
Space cabin atmospheres
Space vehicles - Air pollution Space vehicles - Air quality - Standards Space vehicles - Contamination Space vehicles - Environmental aspects Toxicology - Research - United States |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants""; ""Copyright""; ""Preface""; ""Contents""; ""Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants""; ""INTRODUCTION""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING SMACS""; ""REVIEW OF SMAC REPORTS""; ""REFERENCES""; ""Appendix A Executive Summary of Guidelines for Developing Spacecraft Maximum Allowable Concentration for Space Station�""; ""EXECUTIVE SUMMARY: SPACECRAFT MAXIMUM ALLOWABLE CONCENTRATIONS FOR SPACE STATION CONTAMINANTS""
""ENVIRONMENTAL CONTROL AND LIFE-SUPPORT SYSTEM""""MODIFICATION OF CONTAMINANT TOXICITY BY ENVIRONMENTAL FACTORS""; ""SOURCES AND TYPES OF DATA FOR ESTABLISHMENT OF SMACS""; ""Chemical-Physical Characteristics of Toxicants""; ""In Vitro Toxicity Studies""; ""Animal Toxicity Studies""; ""Clinical and Epidemiological Observations""; ""Pharmacokinetics and Metabolism""; ""Biological Markers""; ""RISK ASSESSMENT (DEVELOPMENT OF EXPOSURE CRITERIA)""; ""ISSUES IN MAKING RECOMMENDATIONS FOR THE ESTABLISHMENT OF SMACS"" ""Appendix B Reports on Spacecraft Maximum Allowable Concentrations (SMACs) for Selected Airborne Contaminants""""B1 ACETALDEHYDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Acute Toxicity""; ""Mucosal Irritation""; ""Miscellaneous Mucosal Effects""; ""Lethality""; ""Subchronic and Chronic Toxicity""; ""Nasal Toxicity""; ""Pulmonary and Renal Toxicity""; ""Carcinogenicity""; ""Genotoxicity""; ""Reproductive and Developmental Toxicity""; ""Synergistic Effects""; ""RATIONALE""; ""Carcinogenicity"" ""Mucosal Irritation""""The Establishment of SMACs""; ""REFERENCES""; ""B2 AMMONIA""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Mechanisms of Tissue Injuries""; ""Mucosal Irritation in Naive Subjects""; ""Mucosal Irritation in Adapted Subjects""; ""Mucosal Irritation in Subjects Of Unknown Adaptation Status""; ""Toxic Effects of Massive Exposures""; ""Animal Models of Ammonia's Respiratory Damage""; ""Metabolic Acidosis""; ""RATIONALE""; ""1-h SMAC and 24-h SMAC""; ""7-d SMAC""; ""30-d SMAC and 180-d SMAC"" ""REFERENCES""""B3 CARBON MONOXIDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS""; ""TOXICITY SUMMARY""; ""Acute Toxicity""; ""Adaptation""; ""Subchronic and Chronic Toxicity""; ""Synergistic Effects""; ""RATIONALE""; ""1-h SMAC""; ""24-h SMAC""; ""7-d SMAC""; ""30-d SMAC and 180-d SMAC""; ""1-h and 24-h SMACs Immediately Following CO Exposure""; ""REFERENCES""; ""B4 FORMALDEHYDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Acute Toxicity"" ""Subchronic and Chronic Toxicity"" |
| Record Nr. | UNINA-9910777584203321 |
| Washington, D.C., : National Academy Press, 1994 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Spacecraft maximum allowable concentrations for selected airborne contaminants . Volume 1 / / Subcommittee on Spacecraft Maximum Allowable Concentrations, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
| Spacecraft maximum allowable concentrations for selected airborne contaminants . Volume 1 / / Subcommittee on Spacecraft Maximum Allowable Concentrations, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1994 |
| Descrizione fisica | 1 online resource (235 p.) |
| Disciplina | 629.477 |
| Soggetto topico |
Space cabin atmospheres
Space vehicles - Air pollution Space vehicles - Air quality - Standards Space vehicles - Contamination Space vehicles - Environmental aspects Toxicology - Research - United States |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants""; ""Copyright""; ""Preface""; ""Contents""; ""Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants""; ""INTRODUCTION""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING SMACS""; ""REVIEW OF SMAC REPORTS""; ""REFERENCES""; ""Appendix A Executive Summary of Guidelines for Developing Spacecraft Maximum Allowable Concentration for Space Station�""; ""EXECUTIVE SUMMARY: SPACECRAFT MAXIMUM ALLOWABLE CONCENTRATIONS FOR SPACE STATION CONTAMINANTS""
""ENVIRONMENTAL CONTROL AND LIFE-SUPPORT SYSTEM""""MODIFICATION OF CONTAMINANT TOXICITY BY ENVIRONMENTAL FACTORS""; ""SOURCES AND TYPES OF DATA FOR ESTABLISHMENT OF SMACS""; ""Chemical-Physical Characteristics of Toxicants""; ""In Vitro Toxicity Studies""; ""Animal Toxicity Studies""; ""Clinical and Epidemiological Observations""; ""Pharmacokinetics and Metabolism""; ""Biological Markers""; ""RISK ASSESSMENT (DEVELOPMENT OF EXPOSURE CRITERIA)""; ""ISSUES IN MAKING RECOMMENDATIONS FOR THE ESTABLISHMENT OF SMACS"" ""Appendix B Reports on Spacecraft Maximum Allowable Concentrations (SMACs) for Selected Airborne Contaminants""""B1 ACETALDEHYDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Acute Toxicity""; ""Mucosal Irritation""; ""Miscellaneous Mucosal Effects""; ""Lethality""; ""Subchronic and Chronic Toxicity""; ""Nasal Toxicity""; ""Pulmonary and Renal Toxicity""; ""Carcinogenicity""; ""Genotoxicity""; ""Reproductive and Developmental Toxicity""; ""Synergistic Effects""; ""RATIONALE""; ""Carcinogenicity"" ""Mucosal Irritation""""The Establishment of SMACs""; ""REFERENCES""; ""B2 AMMONIA""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Mechanisms of Tissue Injuries""; ""Mucosal Irritation in Naive Subjects""; ""Mucosal Irritation in Adapted Subjects""; ""Mucosal Irritation in Subjects Of Unknown Adaptation Status""; ""Toxic Effects of Massive Exposures""; ""Animal Models of Ammonia's Respiratory Damage""; ""Metabolic Acidosis""; ""RATIONALE""; ""1-h SMAC and 24-h SMAC""; ""7-d SMAC""; ""30-d SMAC and 180-d SMAC"" ""REFERENCES""""B3 CARBON MONOXIDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS""; ""TOXICITY SUMMARY""; ""Acute Toxicity""; ""Adaptation""; ""Subchronic and Chronic Toxicity""; ""Synergistic Effects""; ""RATIONALE""; ""1-h SMAC""; ""24-h SMAC""; ""7-d SMAC""; ""30-d SMAC and 180-d SMAC""; ""1-h and 24-h SMACs Immediately Following CO Exposure""; ""REFERENCES""; ""B4 FORMALDEHYDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Acute Toxicity"" ""Subchronic and Chronic Toxicity"" |
| Record Nr. | UNINA-9910829040903321 |
| Washington, D.C., : National Academy Press, 1994 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Update [[electronic resource] /] / National Toxicology Program
| Update [[electronic resource] /] / National Toxicology Program |
| Pubbl/distr/stampa | Research Triangle Park, NC, : National Toxicology Program, 2003- |
| Descrizione fisica | volumes : digital, PDF file |
| Soggetto topico | Toxicology - Research - United States |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Update |
| Record Nr. | UNINA-9910690968303321 |
| Research Triangle Park, NC, : National Toxicology Program, 2003- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
