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Advanced Therapy for Hepatitis C [[electronic resource]]
Advanced Therapy for Hepatitis C [[electronic resource]]
Autore McCaughan Geoffrey W
Pubbl/distr/stampa Hoboken, : Wiley, 2011
Descrizione fisica 1 online resource (233 p.)
Disciplina 616.3/62306
616.362306
Altri autori (Persone) McHutchisonJohn
PawlotskyJean-Michel
Soggetto topico Antiviral agents
Antiviral Agents - therapeutic use
Antiviral Agents -- therapeutic use
Hepatitis C - therapy
Hepatitis C -- therapy
Hepatitis C - Treatment
Hepatitis C -- Treatment
Hepatitis, Viral, Human
Flaviviridae Infections
Anti-Infective Agents
RNA Virus Infections
Therapeutic Uses
Virus Diseases
Hepatitis
Diseases
Liver Diseases
Pharmacologic Actions
Chemical Actions and Uses
Digestive System Diseases
Antiviral Agents
Hepatitis C
Medicine
Health & Biological Sciences
Gastroenterology
ISBN 1-283-28323-9
9786613283238
1-4443-4634-2
1-4443-4631-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Advanced Therapy for Hepatitis C; Contents; Contributors; Preface; Section I Foundations for Understanding Antiviral Therapies in HCV; 1 HCV Replication; 2 Hepatitis C Virus Genotypes; 3 Immune Responses to HCV: Implications for Therapy; 4 Mechanisms of Action of Antiviral Drugs: The Interferons; 5 Pharmacology and Mechanisms of Action of Antiviral Drugs: Ribavirin Analogs; 6 Pharmacology and Mechanisms of Action of Antiviral Drugs: Polymerase Inhibitors; 7 Pharmacology and Mechanisms of Action of Antiviral Drugs: Protease Inhibitors; 8 Measuring Antiviral Responses
Section II Efficacy and Clinical Use of Antiviral Therapies9 Genotype 1: Standard Treatment; 10 Individually Tailored Treatment Strategies in Treatment-naïve Chronic Hepatitis C Genotype 1 Patients; 11 Genotype 1 Relapsers and Non-responders; 12 Standard Therapy for Genotypes 2/3; 13 Altered Dosage or Durations of Current Antiviral Therapy for HCV Genotypes 2 and 3; 14 Genotypes 2 and 3 Relapse and Non-response; 15 Hepatitis C Genotype 4 Therapy: Progress and Challenges; 16 Antivirals in Acute Hepatitis C; 17 Antivirals in Cirrhosis and Portal Hypertension
18 Treatment of Recurrent Hepatitis C Following Liver Transplantation19 Antiviral Treatment in Chronic Hepatitis C Virus Infection with Extrahepatic Manifestations; 20 Cytopenias: How they Limit Therapy and Potential Correction; 21 The Problem of Insulin Resistance and its Effect on Therapy; 22 HIV and Hepatitis C Co-infection; 23 HCV and Racial Differences; 24 HCV and the Pediatric Population; 25 New Horizons: IL28, Direct-acting Antiviral Therapy for HCV; Index
Record Nr. UNINA-9910139591503321
McCaughan Geoffrey W  
Hoboken, : Wiley, 2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Analgesics : from chemistry and pharmacology to clinical application
Analgesics : from chemistry and pharmacology to clinical application
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH, 2002
Descrizione fisica 1 online resource (604 pages)
Disciplina 615/.783
Soggetto topico Analgesics
Central Nervous System Agents
Sensory System Agents
Peripheral Nervous System Agents
Therapeutic Uses
Pharmacologic Actions
Physiological Effects of Drugs
Chemical Actions and Uses
Chemicals and Drugs
Health & Biological Sciences
Pharmacy, Therapeutics, & Pharmacology
Soggetto genere / forma Electronic books.
ISBN 1-280-64448-6
9786610644483
3-527-60561-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910144275603321
[Place of publication not identified], : Wiley VCH, 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Analgesics : from chemistry and pharmacology to clinical application
Analgesics : from chemistry and pharmacology to clinical application
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH, 2002
Descrizione fisica 1 online resource (604 pages)
Disciplina 615/.783
Soggetto topico Analgesics
Central Nervous System Agents
Sensory System Agents
Peripheral Nervous System Agents
Therapeutic Uses
Pharmacologic Actions
Physiological Effects of Drugs
Chemical Actions and Uses
Chemicals and Drugs
Health & Biological Sciences
Pharmacy, Therapeutics, & Pharmacology
ISBN 1-280-64448-6
9786610644483
3-527-60561-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910830272603321
[Place of publication not identified], : Wiley VCH, 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Analgesics : from chemistry and pharmacology to clinical application
Analgesics : from chemistry and pharmacology to clinical application
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH, 2002
Descrizione fisica 1 online resource (604 pages)
Disciplina 615/.783
Soggetto topico Analgesics
Central Nervous System Agents
Sensory System Agents
Peripheral Nervous System Agents
Therapeutic Uses
Pharmacologic Actions
Physiological Effects of Drugs
Chemical Actions and Uses
Chemicals and Drugs
Health & Biological Sciences
Pharmacy, Therapeutics, & Pharmacology
ISBN 1-280-64448-6
9786610644483
3-527-60561-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9911019249103321
[Place of publication not identified], : Wiley VCH, 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Antidepressants, antipsychotics, anxiolytics : from chemistry and pharmacology to clinical application
Antidepressants, antipsychotics, anxiolytics : from chemistry and pharmacology to clinical application
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH, 2007
Soggetto topico Antipsychotic Agents
Anti-Anxiety Agents
Psychopharmacology
Mental Disorders
Antidepressive Agents
Tranquilizing Agents
Pharmacology
Psychiatry and Psychology
Psychotropic Drugs
Behavioral Sciences
Psychiatric Somatic Therapies
Behavioral Disciplines and Activities
Biological Science Disciplines
Central Nervous System Depressants
Central Nervous System Agents
Health Occupations
Disciplines and Occupations
Natural Science Disciplines
Therapeutic Uses
Physiological Effects of Drugs
Pharmacologic Actions
Chemical Actions and Uses
Chemicals and Drugs
ISBN 3-527-61933-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910144271703321
[Place of publication not identified], : Wiley VCH, 2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Antidepressants, antipsychotics, anxiolytics : from chemistry and pharmacology to clinical application
Antidepressants, antipsychotics, anxiolytics : from chemistry and pharmacology to clinical application
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH, 2007
Soggetto topico Antipsychotic Agents
Anti-Anxiety Agents
Psychopharmacology
Mental Disorders
Antidepressive Agents
Tranquilizing Agents
Pharmacology
Psychiatry and Psychology
Psychotropic Drugs
Behavioral Sciences
Psychiatric Somatic Therapies
Behavioral Disciplines and Activities
Biological Science Disciplines
Central Nervous System Depressants
Central Nervous System Agents
Health Occupations
Disciplines and Occupations
Natural Science Disciplines
Therapeutic Uses
Physiological Effects of Drugs
Pharmacologic Actions
Chemical Actions and Uses
Chemicals and Drugs
ISBN 3-527-61933-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910829850003321
[Place of publication not identified], : Wiley VCH, 2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antidepressants, antipsychotics, anxiolytics : from chemistry and pharmacology to clinical application
Antidepressants, antipsychotics, anxiolytics : from chemistry and pharmacology to clinical application
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH, 2007
Soggetto topico Antipsychotic Agents
Anti-Anxiety Agents
Psychopharmacology
Mental Disorders
Antidepressive Agents
Tranquilizing Agents
Pharmacology
Psychiatry and Psychology
Psychotropic Drugs
Behavioral Sciences
Psychiatric Somatic Therapies
Behavioral Disciplines and Activities
Biological Science Disciplines
Central Nervous System Depressants
Central Nervous System Agents
Health Occupations
Disciplines and Occupations
Natural Science Disciplines
Therapeutic Uses
Physiological Effects of Drugs
Pharmacologic Actions
Chemical Actions and Uses
Chemicals and Drugs
ISBN 3-527-61933-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9911018946003321
[Place of publication not identified], : Wiley VCH, 2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antimicrobial Resistance. Global Report on Surveillance [[electronic resource] ] : Global Report on Surveillance
Antimicrobial Resistance. Global Report on Surveillance [[electronic resource] ] : Global Report on Surveillance
Autore Organization World Health
Pubbl/distr/stampa Geneva, : World Health Organization, 2014
Descrizione fisica 1 online resource (254 p.)
Disciplina 616
Soggetto topico Drug resistance -- Periodicals
Drug resistance in microorganisms
Drug resistance
Anti-infective agents - Classification
Drug resistance in microorganisms - Effect of drugs on
Risk management
Risk
Risk Management
Information Science
Drug Resistance
Microbiological Phenomena
Epidemiologic Measurements
Therapeutic Uses
Probability
Pharmacologic Actions
Pharmacological Phenomena
Public Health
Organization and Administration
Statistics as Topic
Health Services Administration
Environment and Public Health
Chemical Actions and Uses
Physiological Phenomena
Health Care Evaluation Mechanisms
Health Care
Epidemiologic Methods
Drug Therapy
Quality of Health Care
Investigative Techniques
Diagnostic Techniques and Procedures
Health Care Quality, Access, and Evaluation
Anti-Infective Agents
Classification
Risk Assessment
Drug Resistance, Microbial
Biology
Health & Biological Sciences
Microbiology & Immunology
Soggetto genere / forma Electronic books.
Publication Formats
Technical Report
ISBN 92-4-069266-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Contents; Foreword; Summary; Acknowledgements; Abbreviations; Introduction; SECTION 01 Resistance to antibacterial drugs; 1.1 Background; 1.1.1 Limitations; 1.2 Regional surveillance of antibacterial resistance; 1.2.1 WHO African Region; 1.2.2 WHO Region of the Americas; 1.2.3 WHO Eastern Mediterranean Region; 1.2.4 WHO European Region; 1.2.5 WHO South-East Asia Region; 1.2.6 WHO Western Pacific Region; 1.3 References; SECTION 02 Resistance to antibacterial drugs in selected bacteria of international concern; 2.1 Availability of national resistance data; 2.1.1 Key messages
2.2 Resistance data on specific pathogens2.2.1 Escherichia coli - resistance to third-generation cephalosporins and to fluoroquinolones; 2.2.2 Klebsiella pneumoniae - resistance to third-generation cephalosporins and to carbapenems; 2.2.3 Staphylococcus aureus - resistance to methicillin; 2.2.4 Streptococcus pneumoniae - resistance (non-susceptibility) to penicillin; 2.2.5 Nontyphoidal Salmonella - resistance to fluoroquinolones; 2.2.6 Shigella species - resistance to fluoroquinolones; 2.2.7 Neisseria gonorrhoeae - decreased susceptibility to third-generation cephalosporins; 2.3 References
SECTION 03 The health and economic burden due to antibacterial resistance3.1 Methods; 3.2 Findings; 3.2.1 Health burden; 3.2.2 Economic burden; 3.3 Knowledge gaps; 3.4 Key messages; 3.5 References; SECTION 04 Surveillance of antimicrobial drug resistance in disease-specific programmes; 4.1 Tuberculosis; 4.1.1 Evolution of drug resistance in tuberculosis; 4.1.2 Surveillance of drug-resistant tuberculosis; 4.1.3 Global public health response to drug-resistant tuberculosis; 4.1.4 Notification of MDR-TB cases and enrolment on treatment
4.1.5 Public health implications: treatment outcomes for multidrug-resistant and extensively drug-resistant tuberculosis4.1.6 Key messages; 4.2 Malaria; 4.2.1 Evolution of antimalarial drug resistance; 4.2.2 Surveillance of antimalarial therapeutic efficacy and resistance; 4.2.3 Global public health implications of antimalarial drug resistance; 4.2.4 Key messages; 4.3 HIV; 4.3.1 Surveillance of anti-HIV drug resistance; 4.3.2 Global public health implications of anti-HIV drug resistance; 4.3.3 Key messages; 4.4 Influenza; 4.4.1 Evolution of resistance in influenza viruses
4.4.2 Anti-influenza drug resistance4.4.3 Surveillance of anti-influenza drug resistance; 4.4.4 Public health implications of anti-influenza drug resistance; 4.4.5 Key messages; 4.5 References; SECTION 05 Surveillance of antimicrobial resistance in other areas; 5.1 Antibacterial resistance in food-producing animals and the food chain; 5.1.1 Ongoing surveillance of antimicrobial resistance in food-producing animals and food; 5.1.2 Integrated surveillance of antimicrobial resistance in foodborne bacteria; 5.1.3 Antimicrobials of particular importance in human and veterinary medicine
5.1.4 Implications for human health from zoonotic transmission of resistant bacteria and genetic material
Record Nr. UNINA-9910511992203321
Organization World Health  
Geneva, : World Health Organization, 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antimicrobial Resistance. Global Report on Surveillance [[electronic resource] ] : Global Report on Surveillance
Antimicrobial Resistance. Global Report on Surveillance [[electronic resource] ] : Global Report on Surveillance
Autore Organization World Health
Pubbl/distr/stampa Geneva, : World Health Organization, 2014
Descrizione fisica 1 online resource (254 p.)
Disciplina 616
Soggetto topico Drug resistance -- Periodicals
Drug resistance in microorganisms
Drug resistance
Anti-infective agents - Classification
Drug resistance in microorganisms - Effect of drugs on
Risk management
Risk
Risk Management
Information Science
Drug Resistance
Microbiological Phenomena
Epidemiologic Measurements
Therapeutic Uses
Probability
Pharmacologic Actions
Pharmacological Phenomena
Public Health
Organization and Administration
Statistics as Topic
Health Services Administration
Environment and Public Health
Chemical Actions and Uses
Physiological Phenomena
Health Care Evaluation Mechanisms
Health Care
Epidemiologic Methods
Drug Therapy
Quality of Health Care
Investigative Techniques
Diagnostic Techniques and Procedures
Health Care Quality, Access, and Evaluation
Anti-Infective Agents
Classification
Risk Assessment
Drug Resistance, Microbial
Biology
Health & Biological Sciences
Microbiology & Immunology
Soggetto genere / forma Publication Formats
Technical Report
ISBN 92-4-069266-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Contents; Foreword; Summary; Acknowledgements; Abbreviations; Introduction; SECTION 01 Resistance to antibacterial drugs; 1.1 Background; 1.1.1 Limitations; 1.2 Regional surveillance of antibacterial resistance; 1.2.1 WHO African Region; 1.2.2 WHO Region of the Americas; 1.2.3 WHO Eastern Mediterranean Region; 1.2.4 WHO European Region; 1.2.5 WHO South-East Asia Region; 1.2.6 WHO Western Pacific Region; 1.3 References; SECTION 02 Resistance to antibacterial drugs in selected bacteria of international concern; 2.1 Availability of national resistance data; 2.1.1 Key messages
2.2 Resistance data on specific pathogens2.2.1 Escherichia coli - resistance to third-generation cephalosporins and to fluoroquinolones; 2.2.2 Klebsiella pneumoniae - resistance to third-generation cephalosporins and to carbapenems; 2.2.3 Staphylococcus aureus - resistance to methicillin; 2.2.4 Streptococcus pneumoniae - resistance (non-susceptibility) to penicillin; 2.2.5 Nontyphoidal Salmonella - resistance to fluoroquinolones; 2.2.6 Shigella species - resistance to fluoroquinolones; 2.2.7 Neisseria gonorrhoeae - decreased susceptibility to third-generation cephalosporins; 2.3 References
SECTION 03 The health and economic burden due to antibacterial resistance3.1 Methods; 3.2 Findings; 3.2.1 Health burden; 3.2.2 Economic burden; 3.3 Knowledge gaps; 3.4 Key messages; 3.5 References; SECTION 04 Surveillance of antimicrobial drug resistance in disease-specific programmes; 4.1 Tuberculosis; 4.1.1 Evolution of drug resistance in tuberculosis; 4.1.2 Surveillance of drug-resistant tuberculosis; 4.1.3 Global public health response to drug-resistant tuberculosis; 4.1.4 Notification of MDR-TB cases and enrolment on treatment
4.1.5 Public health implications: treatment outcomes for multidrug-resistant and extensively drug-resistant tuberculosis4.1.6 Key messages; 4.2 Malaria; 4.2.1 Evolution of antimalarial drug resistance; 4.2.2 Surveillance of antimalarial therapeutic efficacy and resistance; 4.2.3 Global public health implications of antimalarial drug resistance; 4.2.4 Key messages; 4.3 HIV; 4.3.1 Surveillance of anti-HIV drug resistance; 4.3.2 Global public health implications of anti-HIV drug resistance; 4.3.3 Key messages; 4.4 Influenza; 4.4.1 Evolution of resistance in influenza viruses
4.4.2 Anti-influenza drug resistance4.4.3 Surveillance of anti-influenza drug resistance; 4.4.4 Public health implications of anti-influenza drug resistance; 4.4.5 Key messages; 4.5 References; SECTION 05 Surveillance of antimicrobial resistance in other areas; 5.1 Antibacterial resistance in food-producing animals and the food chain; 5.1.1 Ongoing surveillance of antimicrobial resistance in food-producing animals and food; 5.1.2 Integrated surveillance of antimicrobial resistance in foodborne bacteria; 5.1.3 Antimicrobials of particular importance in human and veterinary medicine
5.1.4 Implications for human health from zoonotic transmission of resistant bacteria and genetic material
Record Nr. UNINA-9910786624203321
Organization World Health  
Geneva, : World Health Organization, 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Antiviral Drugs [[electronic resource] ] : From Basic Discovery Through Clinical Trials
Antiviral Drugs [[electronic resource] ] : From Basic Discovery Through Clinical Trials
Autore Kazmierski Wieslaw M
Pubbl/distr/stampa Hoboken, : Wiley, 2011
Descrizione fisica 1 online resource (470 p.)
Disciplina 615/.7924
Soggetto topico Antiviral Agents -- therapeutic use
Antiviral agents
Clinical Trials as Topic
Drug Discovery
Drug Evaluation
Epidemiologic Studies
Chemistry, Pharmaceutical
Evaluation Studies as Topic
Investigative Techniques
Anti-Infective Agents
Epidemiologic Methods
Pharmacology
Therapeutic Uses
Health Care Evaluation Mechanisms
Chemistry
Biological Science Disciplines
Natural Science Disciplines
Quality of Health Care
Public Health
Pharmacologic Actions
Environment and Public Health
Health Care Quality, Access, and Evaluation
Chemical Actions and Uses
Health Care
Antiviral Agents
Health & Biological Sciences
Pharmacy, Therapeutics, & Pharmacology
ISBN 1-283-20363-4
9786613203632
0-470-92935-9
0-470-92934-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ANTIVIRAL DRUGS; CONTENTS; CONTRIBUTORS; PREFACE; PART I HUMAN IMMUNODEFICIENCY VIRUS; 1 Discovery and Development of Atazanavir; 2 Discovery and Development of PL-100, A Novel HIV-1 Protease Inhibitor; 3 Darunavir (Prezista, TMC114): From Bench to Clinic, Improving Treatment Options for HIV-Infected Patients; 4 Discovery and Development of Tipranavir; 5 TMC278 (Rilpivirine): A Next-Generation NNRTI in Phase III Clinical Development for Treatment-Naive Patients; 6 Etravirine: From TMC125 to Intelence: A Treatment Paradigm Shift for HIV-Infected Patients
7 Discovery and Development of Tenofovir Disoproxil Fumarate8 Discovery and Development of Apricitabine; 9 Discovery and Development of Maraviroc and PF-232798: CCR5 Antagonists for the Treatment of HIV-1 Infection; 10 Discovery of the CCR5 Antagonist Vicriviroc (Sch 417690/Sch-D) for the Treatment of HIV-1 Infection; 11 Discovery and Development of HIV-1 Entry Inhibitors That Target gp120; 12 Discovery of MK-0536: A Potential Second-Generation HIV-1 Integrase Strand Transfer Inhibitor with a High Genetic Barrier to Mutation; 13 Discovery and Development of HIV Integrase Inhibitor Raltegravir
14 Elvitegravir: A Novel Monoketo Acid HIV-1 Integrase Strand Transfer InhibitorPART II HEPATITIS C VIRUS; 15 Discovery and Development of Telaprevir; 16 Discovery and Development of BILN 2061 and Follow-up BI 201335; 17 Intervention of Hepatitis C Replication Through NS3-4A, the Protease Inhibitor Boceprevir; 18 Discovery and Development of the HCV NS3/4A Protease Inhibitor Danoprevir (ITMN-191/RG7227); 19 Discovery and Development of the HCV Protease Inhibitor TMC435; 20 Discovery and Clinical Evaluation of the Nucleoside Analog Balapiravir (R1626) for the Treatment of HCV Infection
21 Discovery and Development of PSI-6130/RG712822 Discovery of Cyclophilin Inhibitor NIM811 as a Novel Therapeutic Agent for HCV; 23 HCV Viral Entry Inhibitors; PART III RESPIRATORY SYNCYTIAL VIRUS INHIBITORS; 24 Discovery of the RSV Inhibitor TMC353121; 25 Discovery and Development of Orally Active RSV Fusion Inhibitors; 26 Discovery and Development of RSV604; PART IV INFLUENZA, HEPATITIS B, AND CYTOMEGALOVIRUS INHIBITORS; 27 Discovery and Development of Influenza Virus Sialidase Inhibitor Relenza; 28 Discovery and Development of Entecavir
29 Benzimidazole Ribonucleosides: Novel Drug Candidates for the Prevention and Treatment of Cytomegalovirus DiseasesINDEX; Color Plate
Record Nr. UNINA-9910139613803321
Kazmierski Wieslaw M  
Hoboken, : Wiley, 2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui