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Telomerase [[electronic resource] ] : composition, functions and clinical implications / / Aiden N. Gagnon, [editor]
| Telomerase [[electronic resource] ] : composition, functions and clinical implications / / Aiden N. Gagnon, [editor] |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, Inc., c2010 |
| Descrizione fisica | 1 online resource (173 p.) |
| Disciplina | 616.99/40642 |
| Altri autori (Persone) | GagnonAiden N |
| Collana | DNA--properties and modifications, functions and interactions, recombination and applications |
| Soggetto topico | Telomerase |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-61728-339-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Telomerase beyond telomeres : new roles for an old enzyme / Gabriele Saretzki -- Telomerase and telomeric proteins : a life beyond telomeres / Ilaria Chiodi, Cristina Belgiovine, Chiara Mondello -- Histone deacetylase inhibition as an anticancer telomerase-targeting strategy / Ruman Rahman -- Telomerase role in pituitary adenomas / A. Ortiz-Plata -- Regulations of telomerase activity and WRN gene expression / Fumiaki Uchiumi, Yoshikazu Higami, Sei-ichi Tanuma -- Telomerase and telomere dynamics in cancer : clinical application for cancer diagnosis / Eiso Hiyama, Keiko Hiyama. |
| Record Nr. | UNINA-9910465202203321 |
| New York, : Nova Science Publishers, Inc., c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Telomerase [[electronic resource] ] : composition, functions and clinical implications / / Aiden N. Gagnon, [editor]
| Telomerase [[electronic resource] ] : composition, functions and clinical implications / / Aiden N. Gagnon, [editor] |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, Inc., c2010 |
| Descrizione fisica | 1 online resource (173 p.) |
| Disciplina | 616.99/40642 |
| Altri autori (Persone) | GagnonAiden N |
| Collana | DNA--properties and modifications, functions and interactions, recombination and applications |
| Soggetto topico | Telomerase |
| ISBN | 1-61728-339-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Telomerase beyond telomeres : new roles for an old enzyme / Gabriele Saretzki -- Telomerase and telomeric proteins : a life beyond telomeres / Ilaria Chiodi, Cristina Belgiovine, Chiara Mondello -- Histone deacetylase inhibition as an anticancer telomerase-targeting strategy / Ruman Rahman -- Telomerase role in pituitary adenomas / A. Ortiz-Plata -- Regulations of telomerase activity and WRN gene expression / Fumiaki Uchiumi, Yoshikazu Higami, Sei-ichi Tanuma -- Telomerase and telomere dynamics in cancer : clinical application for cancer diagnosis / Eiso Hiyama, Keiko Hiyama. |
| Record Nr. | UNINA-9910791958603321 |
| New York, : Nova Science Publishers, Inc., c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Telomerase and non-Telomerase Mechanisms of Telomere Maintenance / / Tammy A. Morrish, editor
| Telomerase and non-Telomerase Mechanisms of Telomere Maintenance / / Tammy A. Morrish, editor |
| Pubbl/distr/stampa | London : , : IntechOpen, , [2020] |
| Descrizione fisica | 1 online resource (130 pages) : illustrations |
| Disciplina | 616.9940642 |
| Soggetto topico | Telomerase |
| ISBN | 1-78984-575-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910409758903321 |
| London : , : IntechOpen, , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Telomerase and non-Telomerase Mechanisms of Telomere Maintenance / / edited by Tammy A. Morrish
| Telomerase and non-Telomerase Mechanisms of Telomere Maintenance / / edited by Tammy A. Morrish |
| Pubbl/distr/stampa | London : , : IntechOpen, , 2020 |
| Descrizione fisica | 1 online resource (89 pages) |
| Disciplina | 616.9940642 |
| Soggetto topico | Telomerase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910688424203321 |
| London : , : IntechOpen, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Telomerases [[electronic resource] ] : chemistry, biology, and clinical applications / / edited by Neal F. Lue, Chantal Autexier
| Telomerases [[electronic resource] ] : chemistry, biology, and clinical applications / / edited by Neal F. Lue, Chantal Autexier |
| Edizione | [1st. ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, 2012 |
| Descrizione fisica | 1 online resource (336 p.) |
| Disciplina | 572.8/6 |
| Altri autori (Persone) |
LueNeal F. <1962->
AutexierChantal <1963-> |
| Soggetto topico | Telomerase |
| ISBN |
1-280-76873-8
9786613679505 1-118-26751-6 1-118-26866-0 1-118-26850-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The telomerase complex : an overview / Johanna Mancini and Chantal Autexier -- Telomerase RNA : structure, function, and molecular mechanisms / Yehudi Tzfati and Julian J.-L. Chen -- TERT structure, function, and molecular mechanisms / Emmanuel Skordalakes and Neal F. Lue -- Telomerase biogenesis : RNA Processing, trafficking and protein Interactions / Tara Beattie and Pascal Chartrand -- Transcriptional regulation of human telomerase / Antonella Farsetti and Yu-Sheng Cong -- Telomerase regulation and telomere length homeostasis / Joachim Lingner and David Shore -- Telomere structure in telomerase regulation / Momchil D. Vodenicharov and Raymund J. Wellinger -- Off-telomere functions of telomerase / Kenkichi Masutomi and William C. Hahn -- Murine Models of Dysfunctional Telomeres and Telomerase / Yie Liu and Lea Harrington -- Cellular senescence, telomerase, and cancer in human cells / Phillip G. Smiraldo ... [et al.] -- Telomerase, retrotransposons, and evolution / Irina R. Arkhipova. |
| Record Nr. | UNINA-9910141264703321 |
| Hoboken, N.J., : Wiley, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Telomerases : chemistry, biology, and clinical applications / / edited by Neal F. Lue, Chantal Autexier
| Telomerases : chemistry, biology, and clinical applications / / edited by Neal F. Lue, Chantal Autexier |
| Edizione | [1st. ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, 2012 |
| Descrizione fisica | 1 online resource (336 p.) |
| Disciplina | 572.8/6 |
| Altri autori (Persone) |
LueNeal F. <1962->
AutexierChantal <1963-> |
| Soggetto topico | Telomerase |
| ISBN |
9786613679505
9781280768736 1280768738 9781118267516 1118267516 9781118268667 1118268660 9781118268506 1118268504 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The telomerase complex : an overview / Johanna Mancini and Chantal Autexier -- Telomerase RNA : structure, function, and molecular mechanisms / Yehudi Tzfati and Julian J.-L. Chen -- TERT structure, function, and molecular mechanisms / Emmanuel Skordalakes and Neal F. Lue -- Telomerase biogenesis : RNA Processing, trafficking and protein Interactions / Tara Beattie and Pascal Chartrand -- Transcriptional regulation of human telomerase / Antonella Farsetti and Yu-Sheng Cong -- Telomerase regulation and telomere length homeostasis / Joachim Lingner and David Shore -- Telomere structure in telomerase regulation / Momchil D. Vodenicharov and Raymund J. Wellinger -- Off-telomere functions of telomerase / Kenkichi Masutomi and William C. Hahn -- Murine Models of Dysfunctional Telomeres and Telomerase / Yie Liu and Lea Harrington -- Cellular senescence, telomerase, and cancer in human cells / Phillip G. Smiraldo ... [et al.] -- Telomerase, retrotransposons, and evolution / Irina R. Arkhipova. |
| Record Nr. | UNINA-9910826531303321 |
| Hoboken, N.J., : Wiley, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Telomere territory and cancer / / Parvin Mehdipour, editor
| Telomere territory and cancer / / Parvin Mehdipour, editor |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Dordrecht [Netherlands] ; ; New York, : Springer, 2013 |
| Descrizione fisica | 1 online resource (212 p.) |
| Disciplina | 572.87 |
| Altri autori (Persone) | MehdipourParvin |
| Soggetto topico |
Telomere
Telomerase Cancer cells |
| ISBN |
1-283-63389-2
9786613946348 94-007-4632-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Preface; Contents; Abbreviations and Acronyms; Contributors; Chapter-1; Telomerase: from Aging to Human Cancers; 1.1 Introduction; 1.2 Telomerase in Aging; 1.3 Telomerase in Leukemia; 1.4 Telomerase in Lymphomas; 1.5 Telomerase in Carcinomas; 1.6 Telomerase in Sarcomas; 1.7 Telomerase Targeted for Cancer Therapy; 1.8 Conclusions and Future Perspectives; References; Chapter-2; Telomerase: Basic and Clinical Approaches; 2.1 Introduction; 2.2 Telomerase Structure; 2.3 Telomerase Regulation; 2.3.1 Pretranslational Regulation; 2.3.2 Posttranscriptional Regulation; 2.3.3 Telomerase Activators
2.3.3.1 Akt kinase2.3.3.2 Protein kinase C and IP6; 2.3.4 Telomerase Repressors; 2.3.4.1 c-Abl; 2.3.4.2 PP2A; 2.4 Telomerase Activity and Expression of Its RNA Component (hTR) in Breast Cancer Patients (Adapted from Hosseini et al. 2006a Hosseini et al. 2006b); 2.4.1 Methods; 2.4.2 Results; 2.4.3 Discussion; 2.5 Expression of hTR and hTERT in Human Breast Cancer Patients: A Clinical Based Data (Adapted from Hosseini et al. 2006a Hosseini et al. 2006b); 2.5.1 Results; 2.5.2 Discussion; References; Chapter-3 Detection of Telomerase Activity: A New Strategy for Detecting Low Activity of Telomerase3.1 Introduction; 3.2 TRAP Assay; 3.3 TRAP-SPA; 3.4 Real-Time Quantitative Assay (RQ-TRAP); 3.5 ISTRAP; 3.6 PCR-Free Telomerase Detection; 3.7 TMA/HPA; 3.8 A New Strategy for Detecting Low Activity of Telomerase; 3.8.1 Material and Methods; 3.8.2 Results; 3.8.3 Discussion; References; Chapter-4; Telomere, Regulation and Tumorigenesis; 4.1 Introduction; 4.2 Telomeric DNA; 4.3 Telomeric Proteins and Its Regulation; 4.4 Telomeric Proteins and DNA Repair; 4.5 Telomeric Position Effect and Its Proteins 4.6 Telomere Protection and Maintenance4.7 Telomere Maintenance and DNA Damage Response; 4.8 Telomeres and Homologous Recombination; 4.9 Alternative Mechanism of Telomere Maintenance; 4.10 Telomere Function in Meiosis; 4.11 Telomere Dysfunction and Tumorigenesis; 4.12 Telomere and Telomerase in Brain Tumors; References; Chapter-5; Novel Hypothesis on Telomere Length: Heterogenic Targets as Genomic/Somatic Diverse Value in Breast Cancer and Brain Tumor; 5.1 Introduction; 5.1.1 Techniques to Measure TL At a Glance; 5.2 Cell; 5.2.1 Cell Is Core Spring of Our Life 5.2.2 The Initiative Reports on Tumor Evolution Contributed by5.2.3 Cells Live, Divide and Die; 5.3 Pedigree-Based Insight in Cancer; 5.3.1 The Characteristics and Impact of Pedigree-Based Research; 5.4 Diversity and Evolution; 5.4.1 Hypothesis and Tumorigenesis; 5.4.2 Questions on Some Facts in Cancer Biology; 5.4.3 Diversity; 5.5 Natural Selection; 5.6 Basic Facts About Telomere at a Glance; 5.7 Evolution and Novel Hypothesis on Telomere Length; 5.7.1 Modeling and Hypothesis; 5.7.2 Pedigree as a Core in Cancer Research; 5.7.2.1 Sample Designing; 5.7.2.2 Patients and Control Groups 5.7.2.3 Brief Strategy for Materials and Methods |
| Record Nr. | UNINA-9910437617403321 |
| Dordrecht [Netherlands] ; ; New York, : Springer, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Telomeres [[electronic resource] ] : function, shortening and lengthening / / Leonardo Mancini, editor
| Telomeres [[electronic resource] ] : function, shortening and lengthening / / Leonardo Mancini, editor |
| Pubbl/distr/stampa | New York, : Nova Biomedical Books, c2009 |
| Descrizione fisica | 1 online resource (498 p.) |
| Disciplina | 572.8/7 |
| Altri autori (Persone) | ManciniLeonardo |
| Soggetto topico |
Telomere
Telomerase |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60876-720-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910452470603321 |
| New York, : Nova Biomedical Books, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Telomeres [[electronic resource] ] : function, shortening and lengthening / / Leonardo Mancini, editor
| Telomeres [[electronic resource] ] : function, shortening and lengthening / / Leonardo Mancini, editor |
| Pubbl/distr/stampa | New York, : Nova Biomedical Books, c2009 |
| Descrizione fisica | 1 online resource (498 p.) |
| Disciplina | 572.8/7 |
| Altri autori (Persone) | ManciniLeonardo |
| Soggetto topico |
Telomere
Telomerase |
| ISBN | 1-60876-720-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Telomere dynamics and biology in human progeroid syndromes / Terence Davis, Hannah S.E. Tivey, and David Kipling -- The role of telomere-telomerase system in age-related fitness decline : a tameable process / Giacinto Libertini -- Cytogenetic evaluation of telomere dysfunction : chromosomal aberrations involving telomeres and interstitial telomeric sequences / Alejandro D. Bolzán -- Telomeres-telomerase biology and their role in renal and other chronic diseases / Kordinas Vasileios ... [et al.] -- Telomerase and telomere dynamics in cancer : clinical application for cancer diagnosis / Eiso Hiyama, Keiko Hiyama -- Telomeres and chromosome segregation / Antonella Sgura and Daniela Cimini -- Telomere-based genome-protective responses : a mammalian improvement on the bacterial SOS response? / Barbara A. Gilchrest, Mark S. Eller -- Telomere lengthening from oocyte to embryonic stem cell / Eva Pericuesta ... [et al.] -- Transcriptional activity at the telomeres of chironomus (diptera) : its possible role in the lengthening of the telomeres / J.L. Diez ... [et al.] --
Telomerase activity : application to diagnosis of human carcinoma / Liliana N. Guerra -- Telomere shortening in diabetes mellitus / Nicholas Tentolouris, Athanasia Papazafiropoulou -- Do alterations in the three-dimensional organization of telomeres indicate malignant transformation? / Sandrine Lacoste, Hans Knecht, and Sabine Mai -- Telomeres : function, shortening and lengthening / Barry Flanary -- Telomerase regulation in stem cells : how to flip the switch? / Rich Allsopp -- Telomere maintenance mechanisms in bone and soft tissue tumors / Toshihiro Matsuo ... [et al.] -- Genetic polymorphisms of human telomerase reverse transcriptase (hTERT) : mini review / Yumiko Matsubara, Mitsuru Murata, and Yasuo Ikeda -- Genetic inhibition of telomere lengthening in cancer prevention and treatment / F. Mathias Bollmann -- Telomeres : function, shortening, and lengthening / Barry Flanary -- Clinical implications of telomerase activity in human brain tumors / Hyoung-Joon Chun ... [et al.]. |
| Record Nr. | UNINA-9910779646103321 |
| New York, : Nova Biomedical Books, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Telomeres and telomerase [[electronic resource] /] / [editors, Derek J. Chadwick and Gail Cardew]
| Telomeres and telomerase [[electronic resource] /] / [editors, Derek J. Chadwick and Gail Cardew] |
| Pubbl/distr/stampa | Chichester, England ; ; New York, : John Wiley & Sons, 1997 |
| Descrizione fisica | 1 online resource (252 p.) |
| Disciplina |
572.8
572.87 |
| Altri autori (Persone) |
ChadwickDerek
CardewGail |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Telomere
Telomerase |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-34806-X
9786612348068 0-470-51543-0 0-470-51544-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
TELOMERES AND TELOMERASE; Contents; Participants; Introduction; The telomere and telomerase: how do they interact?; Telomerase and the chromosome end replication problem; General discussion I; The role of the EST genes in yeast telomere replication; Drosophila telornere elongation; General discussion I1; Raplp and telomere length regulation in yeast; Chromatin and ageing in yeast and in mammals; The limited reproductive life span of normal human cells in culture; Human ageing and telorneres; General discussion I11; Telomerase assays in the diagnosis and prognosis of cancer
Mouse models for the study of telomeraseGenetic control of telomerase and replicative senescence in human and rodent cells; Repair and processing events at DNA ends; Telomeres in the haemopoietic system; Final general discussion; Summary; Index of contributors; Subject index |
| Record Nr. | UNINA-9910144011303321 |
| Chichester, England ; ; New York, : John Wiley & Sons, 1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Telomerase
(14)
- Telomere (6)
- Tetrahymena (2)
- Cancer cells (1)