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Model organisms in spinal cord regeneration [[electronic resource] /] / edited by Catherina G. Becker and Thomas Becker
| Model organisms in spinal cord regeneration [[electronic resource] /] / edited by Catherina G. Becker and Thomas Becker |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2007 |
| Descrizione fisica | 1 online resource (425 p.) |
| Disciplina |
616.8
617.482 |
| Altri autori (Persone) |
BeckerCatherina G
BeckerThomas |
| Soggetto topico |
Spinal cord - Regeneration
Regeneration (Biology) |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-85464-2
9786610854646 3-527-61036-7 3-527-61035-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Model Organisms in Spinal Cord Regeneration; Contents; Preface; List of Contributors; Part I Mammalian Models of CNS Regeneration; 1 The Role of Inhibitory Molecules in Limiting Axonal Regeneration in the Mammalian Spinal Cord; 1.1 Introduction; 1.1.1 CNS Neurons Have Widely Differing Phenotypes; 1.2 Difficulties in Assessing Axonal Regeneration in the Mammalian Spinal Cord; 1.2.1 Experimental Lesions and Problems of Interpretation; 1.2.2 Tracing Regenerating Axons; 1.2.2.1 Regeneration of Corticospinal Axons is Difficult to Assess
1.2.2.2 Regeneration of Ascending Dorsal Column Axons Can Be Measured Simply and Accurately1.3 Myelin Proteins as Inhibitors of Axonal Regeneration; 1.3.1 Nogo; 1.3.2 OMgp; 1.3.3 MAG; 1.3.4 The Nogo-66 Receptor, NgR1, (RTN4R), and Related Molecules; 1.3.5 Co-Receptors: LINGO-1, p75 and TROY (TAJ); 1.3.6 Signal Transduction from Myelin-Derived Inhibitory Molecules; 1.3.7 The Role of Nogo-A in Axonal Regeneration in the Spinal Cord; 1.3.7.1 Variations in the Extent of Axonal Regeneration in Different Strains of Nogo Knockout Mice 1.3.7.2 Effects of Antibodies Against Nogo on Axonal Regeneration in Spinal Cord1.3.7.3 Neuronal Nogo-A; 1.3.8 The Role of NgR1, NgR2 and Their Co-Receptors in Axonal Regeneration Within the Spinal Cord; 1.3.8.1 The Distribution of NgR1 and NgR2 Does Not Suggest a General Regeneration-Inhibitory Function in the CNS; 1.3.8.2 Knockout Mice Do Not Provide a Clear Picture of the Role of NgR1 in Regeneration; 1.3.8.3 Pharmacological Blockade of NgR1 Enhances Axonal Sprouting and Regeneration 1.3.8.4 The Pattern of Expression of LINGO-1 and p75 Does Not Suggest a General Role in Inhibiting Regeneration in Vivo1.3.8.5 LINGO-1, p75 and TROY Have Important Roles in Neurite Outgrowth in Vitro, But Their Significance for Axonal Regeneration in Vivo Has Not Yet Been Established; 1.3.9 Effects of MAG and OMgp on Axon Regeneration in the Mammalian CNS; 1.3.10 Strong Evidence That Myelin Proteins Are Not Always Effective Inhibitors of Axonal Regeneration in Vivo; 1.4 Inhibitors at the Lesion Site (Fig. 1.5); 1.4.1 CSPGs 1.4.1.2 Relationship Between the Distribution of CSPGs and Failure of Axonal Regeneration1.4.1.3 Chondroitinase ABC and Axonal Regeneration; 1.4.1.4 Scar-Reducing and Growth-Promoting Effects of Decorin; 1.4.2 Axonal Guidance Molecules Are Present in the Spinal Cord and Their Receptors Are Expressed by Specific Classes of Neuron; 1.4.2.1 Semaphorins; 1.4.2.2 Ephrins; 1.4.2.3 Slits and Netrins in the Mammalian Spinal Cord; 1.5 The Most Consistent Effects of Interfering with Inhibitory Molecules or Their Signaling Are on Raphespinal Axons 1.6 Interfering with Downstream Effectors of Inhibitory Signaling |
| Record Nr. | UNINA-9910144725103321 |
| Weinheim, : Wiley-VCH, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Model organisms in spinal cord regeneration [[electronic resource] /] / edited by Catherina G. Becker and Thomas Becker
| Model organisms in spinal cord regeneration [[electronic resource] /] / edited by Catherina G. Becker and Thomas Becker |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2007 |
| Descrizione fisica | 1 online resource (425 p.) |
| Disciplina |
616.8
617.482 |
| Altri autori (Persone) |
BeckerCatherina G
BeckerThomas |
| Soggetto topico |
Spinal cord - Regeneration
Regeneration (Biology) |
| ISBN |
1-280-85464-2
9786610854646 3-527-61036-7 3-527-61035-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Model Organisms in Spinal Cord Regeneration; Contents; Preface; List of Contributors; Part I Mammalian Models of CNS Regeneration; 1 The Role of Inhibitory Molecules in Limiting Axonal Regeneration in the Mammalian Spinal Cord; 1.1 Introduction; 1.1.1 CNS Neurons Have Widely Differing Phenotypes; 1.2 Difficulties in Assessing Axonal Regeneration in the Mammalian Spinal Cord; 1.2.1 Experimental Lesions and Problems of Interpretation; 1.2.2 Tracing Regenerating Axons; 1.2.2.1 Regeneration of Corticospinal Axons is Difficult to Assess
1.2.2.2 Regeneration of Ascending Dorsal Column Axons Can Be Measured Simply and Accurately1.3 Myelin Proteins as Inhibitors of Axonal Regeneration; 1.3.1 Nogo; 1.3.2 OMgp; 1.3.3 MAG; 1.3.4 The Nogo-66 Receptor, NgR1, (RTN4R), and Related Molecules; 1.3.5 Co-Receptors: LINGO-1, p75 and TROY (TAJ); 1.3.6 Signal Transduction from Myelin-Derived Inhibitory Molecules; 1.3.7 The Role of Nogo-A in Axonal Regeneration in the Spinal Cord; 1.3.7.1 Variations in the Extent of Axonal Regeneration in Different Strains of Nogo Knockout Mice 1.3.7.2 Effects of Antibodies Against Nogo on Axonal Regeneration in Spinal Cord1.3.7.3 Neuronal Nogo-A; 1.3.8 The Role of NgR1, NgR2 and Their Co-Receptors in Axonal Regeneration Within the Spinal Cord; 1.3.8.1 The Distribution of NgR1 and NgR2 Does Not Suggest a General Regeneration-Inhibitory Function in the CNS; 1.3.8.2 Knockout Mice Do Not Provide a Clear Picture of the Role of NgR1 in Regeneration; 1.3.8.3 Pharmacological Blockade of NgR1 Enhances Axonal Sprouting and Regeneration 1.3.8.4 The Pattern of Expression of LINGO-1 and p75 Does Not Suggest a General Role in Inhibiting Regeneration in Vivo1.3.8.5 LINGO-1, p75 and TROY Have Important Roles in Neurite Outgrowth in Vitro, But Their Significance for Axonal Regeneration in Vivo Has Not Yet Been Established; 1.3.9 Effects of MAG and OMgp on Axon Regeneration in the Mammalian CNS; 1.3.10 Strong Evidence That Myelin Proteins Are Not Always Effective Inhibitors of Axonal Regeneration in Vivo; 1.4 Inhibitors at the Lesion Site (Fig. 1.5); 1.4.1 CSPGs 1.4.1.2 Relationship Between the Distribution of CSPGs and Failure of Axonal Regeneration1.4.1.3 Chondroitinase ABC and Axonal Regeneration; 1.4.1.4 Scar-Reducing and Growth-Promoting Effects of Decorin; 1.4.2 Axonal Guidance Molecules Are Present in the Spinal Cord and Their Receptors Are Expressed by Specific Classes of Neuron; 1.4.2.1 Semaphorins; 1.4.2.2 Ephrins; 1.4.2.3 Slits and Netrins in the Mammalian Spinal Cord; 1.5 The Most Consistent Effects of Interfering with Inhibitory Molecules or Their Signaling Are on Raphespinal Axons 1.6 Interfering with Downstream Effectors of Inhibitory Signaling |
| Record Nr. | UNINA-9910830322303321 |
| Weinheim, : Wiley-VCH, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Model organisms in spinal cord regeneration [[electronic resource] /] / edited by Catherina G. Becker and Thomas Becker
| Model organisms in spinal cord regeneration [[electronic resource] /] / edited by Catherina G. Becker and Thomas Becker |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2007 |
| Descrizione fisica | 1 online resource (425 p.) |
| Disciplina |
616.8
617.482 |
| Altri autori (Persone) |
BeckerCatherina G
BeckerThomas |
| Soggetto topico |
Spinal cord - Regeneration
Regeneration (Biology) |
| ISBN |
1-280-85464-2
9786610854646 3-527-61036-7 3-527-61035-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Model Organisms in Spinal Cord Regeneration; Contents; Preface; List of Contributors; Part I Mammalian Models of CNS Regeneration; 1 The Role of Inhibitory Molecules in Limiting Axonal Regeneration in the Mammalian Spinal Cord; 1.1 Introduction; 1.1.1 CNS Neurons Have Widely Differing Phenotypes; 1.2 Difficulties in Assessing Axonal Regeneration in the Mammalian Spinal Cord; 1.2.1 Experimental Lesions and Problems of Interpretation; 1.2.2 Tracing Regenerating Axons; 1.2.2.1 Regeneration of Corticospinal Axons is Difficult to Assess
1.2.2.2 Regeneration of Ascending Dorsal Column Axons Can Be Measured Simply and Accurately1.3 Myelin Proteins as Inhibitors of Axonal Regeneration; 1.3.1 Nogo; 1.3.2 OMgp; 1.3.3 MAG; 1.3.4 The Nogo-66 Receptor, NgR1, (RTN4R), and Related Molecules; 1.3.5 Co-Receptors: LINGO-1, p75 and TROY (TAJ); 1.3.6 Signal Transduction from Myelin-Derived Inhibitory Molecules; 1.3.7 The Role of Nogo-A in Axonal Regeneration in the Spinal Cord; 1.3.7.1 Variations in the Extent of Axonal Regeneration in Different Strains of Nogo Knockout Mice 1.3.7.2 Effects of Antibodies Against Nogo on Axonal Regeneration in Spinal Cord1.3.7.3 Neuronal Nogo-A; 1.3.8 The Role of NgR1, NgR2 and Their Co-Receptors in Axonal Regeneration Within the Spinal Cord; 1.3.8.1 The Distribution of NgR1 and NgR2 Does Not Suggest a General Regeneration-Inhibitory Function in the CNS; 1.3.8.2 Knockout Mice Do Not Provide a Clear Picture of the Role of NgR1 in Regeneration; 1.3.8.3 Pharmacological Blockade of NgR1 Enhances Axonal Sprouting and Regeneration 1.3.8.4 The Pattern of Expression of LINGO-1 and p75 Does Not Suggest a General Role in Inhibiting Regeneration in Vivo1.3.8.5 LINGO-1, p75 and TROY Have Important Roles in Neurite Outgrowth in Vitro, But Their Significance for Axonal Regeneration in Vivo Has Not Yet Been Established; 1.3.9 Effects of MAG and OMgp on Axon Regeneration in the Mammalian CNS; 1.3.10 Strong Evidence That Myelin Proteins Are Not Always Effective Inhibitors of Axonal Regeneration in Vivo; 1.4 Inhibitors at the Lesion Site (Fig. 1.5); 1.4.1 CSPGs 1.4.1.2 Relationship Between the Distribution of CSPGs and Failure of Axonal Regeneration1.4.1.3 Chondroitinase ABC and Axonal Regeneration; 1.4.1.4 Scar-Reducing and Growth-Promoting Effects of Decorin; 1.4.2 Axonal Guidance Molecules Are Present in the Spinal Cord and Their Receptors Are Expressed by Specific Classes of Neuron; 1.4.2.1 Semaphorins; 1.4.2.2 Ephrins; 1.4.2.3 Slits and Netrins in the Mammalian Spinal Cord; 1.5 The Most Consistent Effects of Interfering with Inhibitory Molecules or Their Signaling Are on Raphespinal Axons 1.6 Interfering with Downstream Effectors of Inhibitory Signaling |
| Record Nr. | UNINA-9910840712703321 |
| Weinheim, : Wiley-VCH, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Recovery of Motor Function Following Spinal Cord Injury / / edited by Heidi Fuller and Monte Gates
| Recovery of Motor Function Following Spinal Cord Injury / / edited by Heidi Fuller and Monte Gates |
| Pubbl/distr/stampa | Rijeka, Croatia : , : InTech, , 2016 |
| Descrizione fisica | 1 online resource (330 pages) : illustrations some color |
| Disciplina | 617.482 |
| Soggetto topico | Spinal cord - Regeneration |
| ISBN |
953-51-7290-5
953-51-2498-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910169221803321 |
| Rijeka, Croatia : , : InTech, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
