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Detection of pathogenic infections in neurological disorders through recycling of gene expression data / / Anna-Maria Liebhoff
Detection of pathogenic infections in neurological disorders through recycling of gene expression data / / Anna-Maria Liebhoff
Autore Liebhoff Anna-Maria
Edizione [1. Auflage.]
Pubbl/distr/stampa Göttingen : , : Cuvillier Verlag, , [2021]
Descrizione fisica 1 online resource (143 pages)
Disciplina 579.25
Soggetto topico RNA viruses - Research - Methodology
ISBN 3-7369-6409-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- 1 Introduction -- 2 Biological background -- 2.1 Ribonucleic acid (RNA) -- 2.2 Small RNA -- 2.3 Sequencing -- 2.4 Microbiology -- 2.5 Neurodegenerative diseases -- 2.6 Pathogens in neurological diseases -- 3 Bioinformatics background -- 3.1 Data sources -- 3.2 Metadata and biological ontologies -- 3.3 Read alignment -- 3.4 Comparative analysis -- 3.5 Metagenomic analysis -- 3.6 Integrated analysis pipelines -- 4 Computer science background -- 4.1 Web development -- 4.2 Data science and machine learning -- 5 Small RNA Expression Atlas (SEA) -- 5.1 Background -- 5.2 System architecture -- 5.3 Implementation -- 5.4 System behavior -- 5.5 Results -- 6 Biological discoveries through SEA -- 6.1 Tissue specificity of small RNA -- 6.2 User data and Parkinson's disease -- 6.3 Pathogens in neurodegenerative diseases -- 6.4 Sex specificity of small RNA in human body -- 6.5 Discussion -- 7 Pathogen detection in RNA-seq data -- 7.1 Background -- 7.2 Identification algorithm -- 7.3 Performance measures -- 7.4 Evaluation -- 8 Path(ogen)s to disease -- 8.1 Analysis pipeline -- 8.2 Burkholderia stabilis in frontotemporal dementia -- 8.3 Discussion -- 9 Conclusion -- Bibliography -- A SEA JSON communication objects -- B Pathonoia algorithms -- C Detailed analysis results.
Record Nr. UNINA-9910794549303321
Liebhoff Anna-Maria  
Göttingen : , : Cuvillier Verlag, , [2021]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Detection of pathogenic infections in neurological disorders through recycling of gene expression data / / Anna-Maria Liebhoff
Detection of pathogenic infections in neurological disorders through recycling of gene expression data / / Anna-Maria Liebhoff
Autore Liebhoff Anna-Maria
Edizione [1. Auflage.]
Pubbl/distr/stampa Göttingen : , : Cuvillier Verlag, , [2021]
Descrizione fisica 1 online resource (143 pages)
Disciplina 579.25
Soggetto topico RNA viruses - Research - Methodology
ISBN 3-7369-6409-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- 1 Introduction -- 2 Biological background -- 2.1 Ribonucleic acid (RNA) -- 2.2 Small RNA -- 2.3 Sequencing -- 2.4 Microbiology -- 2.5 Neurodegenerative diseases -- 2.6 Pathogens in neurological diseases -- 3 Bioinformatics background -- 3.1 Data sources -- 3.2 Metadata and biological ontologies -- 3.3 Read alignment -- 3.4 Comparative analysis -- 3.5 Metagenomic analysis -- 3.6 Integrated analysis pipelines -- 4 Computer science background -- 4.1 Web development -- 4.2 Data science and machine learning -- 5 Small RNA Expression Atlas (SEA) -- 5.1 Background -- 5.2 System architecture -- 5.3 Implementation -- 5.4 System behavior -- 5.5 Results -- 6 Biological discoveries through SEA -- 6.1 Tissue specificity of small RNA -- 6.2 User data and Parkinson's disease -- 6.3 Pathogens in neurodegenerative diseases -- 6.4 Sex specificity of small RNA in human body -- 6.5 Discussion -- 7 Pathogen detection in RNA-seq data -- 7.1 Background -- 7.2 Identification algorithm -- 7.3 Performance measures -- 7.4 Evaluation -- 8 Path(ogen)s to disease -- 8.1 Analysis pipeline -- 8.2 Burkholderia stabilis in frontotemporal dementia -- 8.3 Discussion -- 9 Conclusion -- Bibliography -- A SEA JSON communication objects -- B Pathonoia algorithms -- C Detailed analysis results.
Record Nr. UNINA-9910818329903321
Liebhoff Anna-Maria  
Göttingen : , : Cuvillier Verlag, , [2021]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
RNA Viruses Infection / / Yogendra Shah, Jagadish Joshi (editors)
RNA Viruses Infection / / Yogendra Shah, Jagadish Joshi (editors)
Pubbl/distr/stampa London : , : IntechOpen, , 2022
Descrizione fisica 1 online resource (162 pages)
Disciplina 579.25
Soggetto topico RNA viruses - Genetics
RNA viruses - Research - Methodology
ISBN 1-80355-667-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Introductory Chapter: Plan and Preparedness to Prevent and Combat against the Pandemic RNA Virus Infection -- 2. Respiratory Syncytial Virus -- 3. Influenza Viruses: Targetting Conserved Viral Ha-Stem, Matrix and Nucleo-Proteins to Disarm a Resilient and Recurring Pandemic -- 4. COVID-19 Prevention through Vitamin C, D, and Zinc Supplementation: A Small Clinical Study in Two Parts -- 5. Chronic Inflammatory Bowel Disease and Demyelination of the Central Nervous System: A Report on Two Cases -- 6. Neurotropic Virus-Induced Meningoencephalomyelitis -- 7. Impairment of the Cardiovascular System during SARS-CoV-2 Infection -- 8. Ageing and HIV-Risk in Non-Gravid Female Humans -- 9. The Role of IL-6 in RNA Virus Infection.
Record Nr. UNINA-9910633963903321
London : , : IntechOpen, , 2022
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui