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Fused pyrimidines . Part three Pteridines [[electronic resource] /] / D.J. Brown
Fused pyrimidines . Part three Pteridines [[electronic resource] /] / D.J. Brown
Autore Brown D. J
Pubbl/distr/stampa New York, : Wiley & Sons, c1988
Descrizione fisica 1 online resource (762 p.)
Disciplina 547.593
547/.59/05
547/.593
Collana Chemistry of heterocyclic compounds
Soggetto topico Pteridines
Pyrimidines
ISBN 1-282-30165-9
9786612301650
0-470-18689-5
0-470-18837-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto FUSED PYRIMIDINES; Contents; List of Tables; CHAPTER I. INTRODUCTION TO THE PTERIDINES; 1. History; 2. Nomenclature; 3. The Basis of Pteridine Chemistry; 4. A General Summary of Pteridine Chemistry; A. Electrophilic Reactions; B. Direct Nucleophilic Substitutions; C. Nucleophilic Metatheses; (1) Replacement of Halogeno Substituents; (a) By Amino or Substituted-Amino Groups; (b) By Hydroxy-Oxo Substituents; (c) By Alkoxy or Aryloxy Groups; (d) By Mercapto- Thioxo Substituents; (e) By Alkylthio or Arylthio Groups; (f) By Sulfo Groups; (g) By Other Groups; (2) Replacement of Alkoxy Groups
(3) Replacement of Alkylthio Groups(4) Replacement of Sulfo Groups; (5) Replacement of Alkylsulfonyl Groups; D. Other Metatheses; (1) Pteridinones to Chloropteridines; (2) Pteridinones to Pteridinethiones; (3) Pteridinethiones to Pteridinones; (4) Pteridinones to Pteridinamines; (5) Pteridinethiones to Pteridinamines or Pteridinimines; (6) Pteridinamines or Pteridinimines to Pteridinones; E. Addition Reactions; (1) Covalent Hydration and Similar Additions; (2) Addition of Phenyllithium; F. Oxidative Reactions; (1) Nuclear Oxidation; (2) Formation of N-Oxides
(3) Oxidative Modification of Groups(a) C- Methyl to C-Formyl; (b) C-Alkyl to C-Acyl; (c) Alkyl to Carboxy; (d) Hydroxyalkyl to Formyl; (e) Hydroxyalkyl to Carboxy; (f) C-Formyl to Carboxy; (g) C-Acyl to Carboxy; (h) Pteridinethiones to Dipteridinyl Disulfides; (i) Thioxo to Sulfeno, Sulfino, or Sulfo; (j) Alkylthio to Alkylsulfinyl or Alkylsulfonyl; G. Reductive Reactions; (1) Nuclear Reduction; (2) Reductive Removal of Groups; (3) Reductive Modification of Groups; (a) C-Formyl to Hydroxymethyl; (b) Carboxy or Alkoxycarbonyl to Hydroxymethyl; (c) C-Acyl to Hydroxyalkyl or Alkyl
(d) Cyano to Aminomethyl(e) Sulfo, Sulfino, or Sulfeno to Thioxo; H. Other Substituent Modifications; (1) Modification of Alkyl Groups; (2) Modification of Oxo Substituents; (3) Modification of Thioxo Substituents; (4) Modification of Amino Groups; (a) Amino to Acylamino; (b) Amino to Alkylideneamino; (c) Amino to Alkylamino; (d) Transamination; (5) Modification of Carboxy and Related Groups; (a) Carboxy to Related Groups; (b) Alkoxycarbonyl to Related Groups; (c) Carbamoyl to Related Groups; (d) Cyano to Related Groups; (e) C-Formyl to Related Groups; (f) C-Acyl to Related Groups
I. DecarboxylationJ. Homolytic C-Acylation; K. Degradation to Pyrazines or Pyrimidines; (1) Degradation of Pteridine; (2) Degradation of Pteridinones; (3) Degradation of Pteridinamines and Pteridinimines; (4) Degradation of Pteridine N-Oxides; 5. Physical Properties of Pteridines; CHAPTER II. PRIMARY SYNTHESES FROM PYRIMIDINES; 1. The Gabriel and Colman Synthesis from 4,5- Pyrimidinediamines and α-Dicarbonyl Compounds; A. Use of the α-Dialdehyde, Glyoxal; B. Use of α-Aldehydoketones; (1) Simple Cases; (2) Cases with One Functional Group; (3) Cases with Two Functional Groups
(a) The 6- or 7-Alkyl-2-amino-4(3H)-pteridinones
Record Nr. UNINA-9910144282903321
Brown D. J  
New York, : Wiley & Sons, c1988
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Fused pyrimidines . Part three Pteridines [[electronic resource] /] / D.J. Brown
Fused pyrimidines . Part three Pteridines [[electronic resource] /] / D.J. Brown
Autore Brown D. J
Pubbl/distr/stampa New York, : Wiley & Sons, c1988
Descrizione fisica 1 online resource (762 p.)
Disciplina 547.593
547/.59/05
547/.593
Collana Chemistry of heterocyclic compounds
Soggetto topico Pteridines
Pyrimidines
ISBN 1-282-30165-9
9786612301650
0-470-18689-5
0-470-18837-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto FUSED PYRIMIDINES; Contents; List of Tables; CHAPTER I. INTRODUCTION TO THE PTERIDINES; 1. History; 2. Nomenclature; 3. The Basis of Pteridine Chemistry; 4. A General Summary of Pteridine Chemistry; A. Electrophilic Reactions; B. Direct Nucleophilic Substitutions; C. Nucleophilic Metatheses; (1) Replacement of Halogeno Substituents; (a) By Amino or Substituted-Amino Groups; (b) By Hydroxy-Oxo Substituents; (c) By Alkoxy or Aryloxy Groups; (d) By Mercapto- Thioxo Substituents; (e) By Alkylthio or Arylthio Groups; (f) By Sulfo Groups; (g) By Other Groups; (2) Replacement of Alkoxy Groups
(3) Replacement of Alkylthio Groups(4) Replacement of Sulfo Groups; (5) Replacement of Alkylsulfonyl Groups; D. Other Metatheses; (1) Pteridinones to Chloropteridines; (2) Pteridinones to Pteridinethiones; (3) Pteridinethiones to Pteridinones; (4) Pteridinones to Pteridinamines; (5) Pteridinethiones to Pteridinamines or Pteridinimines; (6) Pteridinamines or Pteridinimines to Pteridinones; E. Addition Reactions; (1) Covalent Hydration and Similar Additions; (2) Addition of Phenyllithium; F. Oxidative Reactions; (1) Nuclear Oxidation; (2) Formation of N-Oxides
(3) Oxidative Modification of Groups(a) C- Methyl to C-Formyl; (b) C-Alkyl to C-Acyl; (c) Alkyl to Carboxy; (d) Hydroxyalkyl to Formyl; (e) Hydroxyalkyl to Carboxy; (f) C-Formyl to Carboxy; (g) C-Acyl to Carboxy; (h) Pteridinethiones to Dipteridinyl Disulfides; (i) Thioxo to Sulfeno, Sulfino, or Sulfo; (j) Alkylthio to Alkylsulfinyl or Alkylsulfonyl; G. Reductive Reactions; (1) Nuclear Reduction; (2) Reductive Removal of Groups; (3) Reductive Modification of Groups; (a) C-Formyl to Hydroxymethyl; (b) Carboxy or Alkoxycarbonyl to Hydroxymethyl; (c) C-Acyl to Hydroxyalkyl or Alkyl
(d) Cyano to Aminomethyl(e) Sulfo, Sulfino, or Sulfeno to Thioxo; H. Other Substituent Modifications; (1) Modification of Alkyl Groups; (2) Modification of Oxo Substituents; (3) Modification of Thioxo Substituents; (4) Modification of Amino Groups; (a) Amino to Acylamino; (b) Amino to Alkylideneamino; (c) Amino to Alkylamino; (d) Transamination; (5) Modification of Carboxy and Related Groups; (a) Carboxy to Related Groups; (b) Alkoxycarbonyl to Related Groups; (c) Carbamoyl to Related Groups; (d) Cyano to Related Groups; (e) C-Formyl to Related Groups; (f) C-Acyl to Related Groups
I. DecarboxylationJ. Homolytic C-Acylation; K. Degradation to Pyrazines or Pyrimidines; (1) Degradation of Pteridine; (2) Degradation of Pteridinones; (3) Degradation of Pteridinamines and Pteridinimines; (4) Degradation of Pteridine N-Oxides; 5. Physical Properties of Pteridines; CHAPTER II. PRIMARY SYNTHESES FROM PYRIMIDINES; 1. The Gabriel and Colman Synthesis from 4,5- Pyrimidinediamines and α-Dicarbonyl Compounds; A. Use of the α-Dialdehyde, Glyoxal; B. Use of α-Aldehydoketones; (1) Simple Cases; (2) Cases with One Functional Group; (3) Cases with Two Functional Groups
(a) The 6- or 7-Alkyl-2-amino-4(3H)-pteridinones
Record Nr. UNINA-9910830071703321
Brown D. J  
New York, : Wiley & Sons, c1988
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Fused pyrimidines . Part three Pteridines [[electronic resource] /] / D.J. Brown
Fused pyrimidines . Part three Pteridines [[electronic resource] /] / D.J. Brown
Autore Brown D. J
Pubbl/distr/stampa New York, : Wiley & Sons, c1988
Descrizione fisica 1 online resource (762 p.)
Disciplina 547.593
547/.59/05
547/.593
Collana Chemistry of heterocyclic compounds
Soggetto topico Pteridines
Pyrimidines
ISBN 1-282-30165-9
9786612301650
0-470-18689-5
0-470-18837-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto FUSED PYRIMIDINES; Contents; List of Tables; CHAPTER I. INTRODUCTION TO THE PTERIDINES; 1. History; 2. Nomenclature; 3. The Basis of Pteridine Chemistry; 4. A General Summary of Pteridine Chemistry; A. Electrophilic Reactions; B. Direct Nucleophilic Substitutions; C. Nucleophilic Metatheses; (1) Replacement of Halogeno Substituents; (a) By Amino or Substituted-Amino Groups; (b) By Hydroxy-Oxo Substituents; (c) By Alkoxy or Aryloxy Groups; (d) By Mercapto- Thioxo Substituents; (e) By Alkylthio or Arylthio Groups; (f) By Sulfo Groups; (g) By Other Groups; (2) Replacement of Alkoxy Groups
(3) Replacement of Alkylthio Groups(4) Replacement of Sulfo Groups; (5) Replacement of Alkylsulfonyl Groups; D. Other Metatheses; (1) Pteridinones to Chloropteridines; (2) Pteridinones to Pteridinethiones; (3) Pteridinethiones to Pteridinones; (4) Pteridinones to Pteridinamines; (5) Pteridinethiones to Pteridinamines or Pteridinimines; (6) Pteridinamines or Pteridinimines to Pteridinones; E. Addition Reactions; (1) Covalent Hydration and Similar Additions; (2) Addition of Phenyllithium; F. Oxidative Reactions; (1) Nuclear Oxidation; (2) Formation of N-Oxides
(3) Oxidative Modification of Groups(a) C- Methyl to C-Formyl; (b) C-Alkyl to C-Acyl; (c) Alkyl to Carboxy; (d) Hydroxyalkyl to Formyl; (e) Hydroxyalkyl to Carboxy; (f) C-Formyl to Carboxy; (g) C-Acyl to Carboxy; (h) Pteridinethiones to Dipteridinyl Disulfides; (i) Thioxo to Sulfeno, Sulfino, or Sulfo; (j) Alkylthio to Alkylsulfinyl or Alkylsulfonyl; G. Reductive Reactions; (1) Nuclear Reduction; (2) Reductive Removal of Groups; (3) Reductive Modification of Groups; (a) C-Formyl to Hydroxymethyl; (b) Carboxy or Alkoxycarbonyl to Hydroxymethyl; (c) C-Acyl to Hydroxyalkyl or Alkyl
(d) Cyano to Aminomethyl(e) Sulfo, Sulfino, or Sulfeno to Thioxo; H. Other Substituent Modifications; (1) Modification of Alkyl Groups; (2) Modification of Oxo Substituents; (3) Modification of Thioxo Substituents; (4) Modification of Amino Groups; (a) Amino to Acylamino; (b) Amino to Alkylideneamino; (c) Amino to Alkylamino; (d) Transamination; (5) Modification of Carboxy and Related Groups; (a) Carboxy to Related Groups; (b) Alkoxycarbonyl to Related Groups; (c) Carbamoyl to Related Groups; (d) Cyano to Related Groups; (e) C-Formyl to Related Groups; (f) C-Acyl to Related Groups
I. DecarboxylationJ. Homolytic C-Acylation; K. Degradation to Pyrazines or Pyrimidines; (1) Degradation of Pteridine; (2) Degradation of Pteridinones; (3) Degradation of Pteridinamines and Pteridinimines; (4) Degradation of Pteridine N-Oxides; 5. Physical Properties of Pteridines; CHAPTER II. PRIMARY SYNTHESES FROM PYRIMIDINES; 1. The Gabriel and Colman Synthesis from 4,5- Pyrimidinediamines and α-Dicarbonyl Compounds; A. Use of the α-Dialdehyde, Glyoxal; B. Use of α-Aldehydoketones; (1) Simple Cases; (2) Cases with One Functional Group; (3) Cases with Two Functional Groups
(a) The 6- or 7-Alkyl-2-amino-4(3H)-pteridinones
Record Nr. UNINA-9910840697603321
Brown D. J  
New York, : Wiley & Sons, c1988
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Fused pyrimidines . Part four Miscellaneous fused pyrimidines [[electronic resource] /] / Thomas J. Delia
Fused pyrimidines . Part four Miscellaneous fused pyrimidines [[electronic resource] /] / Thomas J. Delia
Autore Delia Thomas J
Pubbl/distr/stampa New York, : Interscience Publishers, 1992
Descrizione fisica 1 online resource (338 p.)
Disciplina 547.593
547.7/9
547/.59/05
547/.593
Altri autori (Persone) BrownD. J
ArmaregoW. L. F
Collana The chemistry of heterocyclic compounds
Soggetto topico Pyrimidines
Heterocyclic compounds
Soggetto genere / forma Electronic books.
ISBN 1-282-30166-7
9786612301667
0-470-18690-9
0-470-18838-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto FUSED PYRIMIDINES: Miscellaneous Fused Pyrimidines; Contents; CHAPTER I. PYRIDOPYRIMIDINES; 1. Introduction; 2. Methods of Synthesis of the Ring System; A. Synthesis of Pyrido[3,2-d]pyrimidines; (1) From Pyrimidines; (2) From Pyridines; B. Synthesis of Pyrido[4,3-d]pyrimidines; (1) From Pyrimidines; (2) From Pyridines; C. Synthesis of Pyrido[3,4-d]pyrimidines; (1) From Pyrimidines; (2) From Pyridines; D. Synthesis of Pyrido[2,3-d]pyrimidines; (1) From Pyrimidines; (a) Formation of Bond 4a-5; (b) Formation of Bond 5-6; (c) Formation of Bond 7-8; (d) Formation of Bond 8-8a; (2) From Pyridines
(a) Formation of Bond 8a-l(b) Formation of Bond 1-2; (c) Formation of Bond 2-3; (d) Formation of Bond 3-4; (e) Formation of Bond 4-4a; 3. Reactions; A. Of Pyrido[3,2-d]pyrimidines; B. Of Pyrido[4,3-d]pyrimidines; C. Of Pyrido[3,4-d]pyrimidines; D. Of Pyrido[2,3-d]pyrimidines; (1) With Nucleophiles; (2) With Electrophiles; (3) Reductions; (4) Oxidations; 4. Patent Literature; 5. Tables; Table 1. Derivatives of Pyrido[3,2-d]pyrimidine; Table 2. Derivatives of Pyrido[4,3-d]pyrimidines; Table 3. Derivatives of Pyrido[3,4-d]pyrimidines; Table 4. Derivatives of 2,4-Diaminopyrido[2,3-d]pyrimidines
Table 5. Derivatives of 2-Amino-4-hydroxypyrido[2,3-d]pyrimidinesTable 6. Derivatives of 2-Aminopyrido[2,3-d]pyrimidines; Table 7. Derivatives of 4-Aminopyrido[2,3-d]pyrimidines; Table 8. Derivatives of 2,4-Dihydroxypyrido[2,3-d]pyrimidines; Table 9. Derivatives of 2-Hydroxypyrido[2,3-d]pyrimidines; Table 10. Derivatives of 4-Hydroxypyrido[2,3-d]pyrimidines; Table 11. Derivatives of 4-Amino-2-mercaptopyrido[2,3-d]pyrimidines; Table 12. Derivatives of 4-Hydroxy-2-mercaptopyrido[2,3-d]pyrimidines; Table 13. Derivatives of 2-Mercapto- and 4-Mercaptopyrido[2,3-d]pyrimidines
Table 14. Derivatives of Pyrido[2,3-d]pyrimidines6. References; CHAPTER II. PYRANO- AND THIOPYRANOPYRIMIDINES; 1. Nomenclature; 2. Methods of Synthesis of the Ring System; A. Synthesis of Pyrano[2,3-d]pyrimidines; (1) From Pyrimidines; (2) From Pyrans; (3) From Nonheteroaromatic Precursors; B. Synthesis of Pyrano[4,3-d]pyrimidines; (1) From Pyrimidines; (2) From Pyrans; C. Synthesis of Pyrano[3,2-d]pyrimidines; (1) From Pyrimidines; (2) From Pyrans; D. Synthesis of Thiopyrano[2,3-d]pyrimidines; (1) From Pyrimidines; (2) From Thiopyrans; E. Synthesis of Thiopyrano[3,4-d]pyrimidines
F. Synthesis of Thiopyrano[4,3-d]pyrimidines3. Reactions; A. With Nucleophilic Reagents; B. Other Reactions; 4. Patent Literature; 5. Tables; Table 1. The Pyrano[2,3-d]pyrimidines; Table 2. The Pyrano[4,3-d]pyrimidines; Table 3. Miscellaneous Pyranopyrimidines; Table 4. The Thiopyrano[2,3-d]pyrimidines; Table 5. The Thiopyrano[3,4-d]pyrimidines; 6. References; CHAPTER III. PYRIMIDOPYRIMIDINES; 1. Nomenclature; 2. Methods of Synthesis of the Ring System; A. Synthesis of Pyrimido[4,5-d]pyrimidines; (1) From Pyrimidines with Amino Groups Adjacent to Hydrogen
(2) From Pyrimidines with Amino Groups Adjacent to Nitriles
Record Nr. UNINA-9910144282703321
Delia Thomas J  
New York, : Interscience Publishers, 1992
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Fused pyrimidines . Part four Miscellaneous fused pyrimidines [[electronic resource] /] / Thomas J. Delia
Fused pyrimidines . Part four Miscellaneous fused pyrimidines [[electronic resource] /] / Thomas J. Delia
Autore Delia Thomas J
Pubbl/distr/stampa New York, : Interscience Publishers, 1992
Descrizione fisica 1 online resource (338 p.)
Disciplina 547.593
547.7/9
547/.59/05
547/.593
Altri autori (Persone) BrownD. J
ArmaregoW. L. F
Collana The chemistry of heterocyclic compounds
Soggetto topico Pyrimidines
Heterocyclic compounds
ISBN 1-282-30166-7
9786612301667
0-470-18690-9
0-470-18838-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto FUSED PYRIMIDINES: Miscellaneous Fused Pyrimidines; Contents; CHAPTER I. PYRIDOPYRIMIDINES; 1. Introduction; 2. Methods of Synthesis of the Ring System; A. Synthesis of Pyrido[3,2-d]pyrimidines; (1) From Pyrimidines; (2) From Pyridines; B. Synthesis of Pyrido[4,3-d]pyrimidines; (1) From Pyrimidines; (2) From Pyridines; C. Synthesis of Pyrido[3,4-d]pyrimidines; (1) From Pyrimidines; (2) From Pyridines; D. Synthesis of Pyrido[2,3-d]pyrimidines; (1) From Pyrimidines; (a) Formation of Bond 4a-5; (b) Formation of Bond 5-6; (c) Formation of Bond 7-8; (d) Formation of Bond 8-8a; (2) From Pyridines
(a) Formation of Bond 8a-l(b) Formation of Bond 1-2; (c) Formation of Bond 2-3; (d) Formation of Bond 3-4; (e) Formation of Bond 4-4a; 3. Reactions; A. Of Pyrido[3,2-d]pyrimidines; B. Of Pyrido[4,3-d]pyrimidines; C. Of Pyrido[3,4-d]pyrimidines; D. Of Pyrido[2,3-d]pyrimidines; (1) With Nucleophiles; (2) With Electrophiles; (3) Reductions; (4) Oxidations; 4. Patent Literature; 5. Tables; Table 1. Derivatives of Pyrido[3,2-d]pyrimidine; Table 2. Derivatives of Pyrido[4,3-d]pyrimidines; Table 3. Derivatives of Pyrido[3,4-d]pyrimidines; Table 4. Derivatives of 2,4-Diaminopyrido[2,3-d]pyrimidines
Table 5. Derivatives of 2-Amino-4-hydroxypyrido[2,3-d]pyrimidinesTable 6. Derivatives of 2-Aminopyrido[2,3-d]pyrimidines; Table 7. Derivatives of 4-Aminopyrido[2,3-d]pyrimidines; Table 8. Derivatives of 2,4-Dihydroxypyrido[2,3-d]pyrimidines; Table 9. Derivatives of 2-Hydroxypyrido[2,3-d]pyrimidines; Table 10. Derivatives of 4-Hydroxypyrido[2,3-d]pyrimidines; Table 11. Derivatives of 4-Amino-2-mercaptopyrido[2,3-d]pyrimidines; Table 12. Derivatives of 4-Hydroxy-2-mercaptopyrido[2,3-d]pyrimidines; Table 13. Derivatives of 2-Mercapto- and 4-Mercaptopyrido[2,3-d]pyrimidines
Table 14. Derivatives of Pyrido[2,3-d]pyrimidines6. References; CHAPTER II. PYRANO- AND THIOPYRANOPYRIMIDINES; 1. Nomenclature; 2. Methods of Synthesis of the Ring System; A. Synthesis of Pyrano[2,3-d]pyrimidines; (1) From Pyrimidines; (2) From Pyrans; (3) From Nonheteroaromatic Precursors; B. Synthesis of Pyrano[4,3-d]pyrimidines; (1) From Pyrimidines; (2) From Pyrans; C. Synthesis of Pyrano[3,2-d]pyrimidines; (1) From Pyrimidines; (2) From Pyrans; D. Synthesis of Thiopyrano[2,3-d]pyrimidines; (1) From Pyrimidines; (2) From Thiopyrans; E. Synthesis of Thiopyrano[3,4-d]pyrimidines
F. Synthesis of Thiopyrano[4,3-d]pyrimidines3. Reactions; A. With Nucleophilic Reagents; B. Other Reactions; 4. Patent Literature; 5. Tables; Table 1. The Pyrano[2,3-d]pyrimidines; Table 2. The Pyrano[4,3-d]pyrimidines; Table 3. Miscellaneous Pyranopyrimidines; Table 4. The Thiopyrano[2,3-d]pyrimidines; Table 5. The Thiopyrano[3,4-d]pyrimidines; 6. References; CHAPTER III. PYRIMIDOPYRIMIDINES; 1. Nomenclature; 2. Methods of Synthesis of the Ring System; A. Synthesis of Pyrimido[4,5-d]pyrimidines; (1) From Pyrimidines with Amino Groups Adjacent to Hydrogen
(2) From Pyrimidines with Amino Groups Adjacent to Nitriles
Record Nr. UNISA-996202924903316
Delia Thomas J  
New York, : Interscience Publishers, 1992
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui
Fused pyrimidines . Part four Miscellaneous fused pyrimidines [[electronic resource] /] / Thomas J. Delia
Fused pyrimidines . Part four Miscellaneous fused pyrimidines [[electronic resource] /] / Thomas J. Delia
Autore Delia Thomas J
Pubbl/distr/stampa New York, : Interscience Publishers, 1992
Descrizione fisica 1 online resource (338 p.)
Disciplina 547.593
547.7/9
547/.59/05
547/.593
Altri autori (Persone) BrownD. J
ArmaregoW. L. F
Collana The chemistry of heterocyclic compounds
Soggetto topico Pyrimidines
Heterocyclic compounds
ISBN 1-282-30166-7
9786612301667
0-470-18690-9
0-470-18838-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto FUSED PYRIMIDINES: Miscellaneous Fused Pyrimidines; Contents; CHAPTER I. PYRIDOPYRIMIDINES; 1. Introduction; 2. Methods of Synthesis of the Ring System; A. Synthesis of Pyrido[3,2-d]pyrimidines; (1) From Pyrimidines; (2) From Pyridines; B. Synthesis of Pyrido[4,3-d]pyrimidines; (1) From Pyrimidines; (2) From Pyridines; C. Synthesis of Pyrido[3,4-d]pyrimidines; (1) From Pyrimidines; (2) From Pyridines; D. Synthesis of Pyrido[2,3-d]pyrimidines; (1) From Pyrimidines; (a) Formation of Bond 4a-5; (b) Formation of Bond 5-6; (c) Formation of Bond 7-8; (d) Formation of Bond 8-8a; (2) From Pyridines
(a) Formation of Bond 8a-l(b) Formation of Bond 1-2; (c) Formation of Bond 2-3; (d) Formation of Bond 3-4; (e) Formation of Bond 4-4a; 3. Reactions; A. Of Pyrido[3,2-d]pyrimidines; B. Of Pyrido[4,3-d]pyrimidines; C. Of Pyrido[3,4-d]pyrimidines; D. Of Pyrido[2,3-d]pyrimidines; (1) With Nucleophiles; (2) With Electrophiles; (3) Reductions; (4) Oxidations; 4. Patent Literature; 5. Tables; Table 1. Derivatives of Pyrido[3,2-d]pyrimidine; Table 2. Derivatives of Pyrido[4,3-d]pyrimidines; Table 3. Derivatives of Pyrido[3,4-d]pyrimidines; Table 4. Derivatives of 2,4-Diaminopyrido[2,3-d]pyrimidines
Table 5. Derivatives of 2-Amino-4-hydroxypyrido[2,3-d]pyrimidinesTable 6. Derivatives of 2-Aminopyrido[2,3-d]pyrimidines; Table 7. Derivatives of 4-Aminopyrido[2,3-d]pyrimidines; Table 8. Derivatives of 2,4-Dihydroxypyrido[2,3-d]pyrimidines; Table 9. Derivatives of 2-Hydroxypyrido[2,3-d]pyrimidines; Table 10. Derivatives of 4-Hydroxypyrido[2,3-d]pyrimidines; Table 11. Derivatives of 4-Amino-2-mercaptopyrido[2,3-d]pyrimidines; Table 12. Derivatives of 4-Hydroxy-2-mercaptopyrido[2,3-d]pyrimidines; Table 13. Derivatives of 2-Mercapto- and 4-Mercaptopyrido[2,3-d]pyrimidines
Table 14. Derivatives of Pyrido[2,3-d]pyrimidines6. References; CHAPTER II. PYRANO- AND THIOPYRANOPYRIMIDINES; 1. Nomenclature; 2. Methods of Synthesis of the Ring System; A. Synthesis of Pyrano[2,3-d]pyrimidines; (1) From Pyrimidines; (2) From Pyrans; (3) From Nonheteroaromatic Precursors; B. Synthesis of Pyrano[4,3-d]pyrimidines; (1) From Pyrimidines; (2) From Pyrans; C. Synthesis of Pyrano[3,2-d]pyrimidines; (1) From Pyrimidines; (2) From Pyrans; D. Synthesis of Thiopyrano[2,3-d]pyrimidines; (1) From Pyrimidines; (2) From Thiopyrans; E. Synthesis of Thiopyrano[3,4-d]pyrimidines
F. Synthesis of Thiopyrano[4,3-d]pyrimidines3. Reactions; A. With Nucleophilic Reagents; B. Other Reactions; 4. Patent Literature; 5. Tables; Table 1. The Pyrano[2,3-d]pyrimidines; Table 2. The Pyrano[4,3-d]pyrimidines; Table 3. Miscellaneous Pyranopyrimidines; Table 4. The Thiopyrano[2,3-d]pyrimidines; Table 5. The Thiopyrano[3,4-d]pyrimidines; 6. References; CHAPTER III. PYRIMIDOPYRIMIDINES; 1. Nomenclature; 2. Methods of Synthesis of the Ring System; A. Synthesis of Pyrimido[4,5-d]pyrimidines; (1) From Pyrimidines with Amino Groups Adjacent to Hydrogen
(2) From Pyrimidines with Amino Groups Adjacent to Nitriles
Record Nr. UNINA-9910830646803321
Delia Thomas J  
New York, : Interscience Publishers, 1992
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Fused pyrimidines . Part four Miscellaneous fused pyrimidines [[electronic resource] /] / Thomas J. Delia
Fused pyrimidines . Part four Miscellaneous fused pyrimidines [[electronic resource] /] / Thomas J. Delia
Autore Delia Thomas J
Pubbl/distr/stampa New York, : Interscience Publishers, 1992
Descrizione fisica 1 online resource (338 p.)
Disciplina 547.593
547.7/9
547/.59/05
547/.593
Altri autori (Persone) BrownD. J
ArmaregoW. L. F
Collana The chemistry of heterocyclic compounds
Soggetto topico Pyrimidines
Heterocyclic compounds
ISBN 1-282-30166-7
9786612301667
0-470-18690-9
0-470-18838-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto FUSED PYRIMIDINES: Miscellaneous Fused Pyrimidines; Contents; CHAPTER I. PYRIDOPYRIMIDINES; 1. Introduction; 2. Methods of Synthesis of the Ring System; A. Synthesis of Pyrido[3,2-d]pyrimidines; (1) From Pyrimidines; (2) From Pyridines; B. Synthesis of Pyrido[4,3-d]pyrimidines; (1) From Pyrimidines; (2) From Pyridines; C. Synthesis of Pyrido[3,4-d]pyrimidines; (1) From Pyrimidines; (2) From Pyridines; D. Synthesis of Pyrido[2,3-d]pyrimidines; (1) From Pyrimidines; (a) Formation of Bond 4a-5; (b) Formation of Bond 5-6; (c) Formation of Bond 7-8; (d) Formation of Bond 8-8a; (2) From Pyridines
(a) Formation of Bond 8a-l(b) Formation of Bond 1-2; (c) Formation of Bond 2-3; (d) Formation of Bond 3-4; (e) Formation of Bond 4-4a; 3. Reactions; A. Of Pyrido[3,2-d]pyrimidines; B. Of Pyrido[4,3-d]pyrimidines; C. Of Pyrido[3,4-d]pyrimidines; D. Of Pyrido[2,3-d]pyrimidines; (1) With Nucleophiles; (2) With Electrophiles; (3) Reductions; (4) Oxidations; 4. Patent Literature; 5. Tables; Table 1. Derivatives of Pyrido[3,2-d]pyrimidine; Table 2. Derivatives of Pyrido[4,3-d]pyrimidines; Table 3. Derivatives of Pyrido[3,4-d]pyrimidines; Table 4. Derivatives of 2,4-Diaminopyrido[2,3-d]pyrimidines
Table 5. Derivatives of 2-Amino-4-hydroxypyrido[2,3-d]pyrimidinesTable 6. Derivatives of 2-Aminopyrido[2,3-d]pyrimidines; Table 7. Derivatives of 4-Aminopyrido[2,3-d]pyrimidines; Table 8. Derivatives of 2,4-Dihydroxypyrido[2,3-d]pyrimidines; Table 9. Derivatives of 2-Hydroxypyrido[2,3-d]pyrimidines; Table 10. Derivatives of 4-Hydroxypyrido[2,3-d]pyrimidines; Table 11. Derivatives of 4-Amino-2-mercaptopyrido[2,3-d]pyrimidines; Table 12. Derivatives of 4-Hydroxy-2-mercaptopyrido[2,3-d]pyrimidines; Table 13. Derivatives of 2-Mercapto- and 4-Mercaptopyrido[2,3-d]pyrimidines
Table 14. Derivatives of Pyrido[2,3-d]pyrimidines6. References; CHAPTER II. PYRANO- AND THIOPYRANOPYRIMIDINES; 1. Nomenclature; 2. Methods of Synthesis of the Ring System; A. Synthesis of Pyrano[2,3-d]pyrimidines; (1) From Pyrimidines; (2) From Pyrans; (3) From Nonheteroaromatic Precursors; B. Synthesis of Pyrano[4,3-d]pyrimidines; (1) From Pyrimidines; (2) From Pyrans; C. Synthesis of Pyrano[3,2-d]pyrimidines; (1) From Pyrimidines; (2) From Pyrans; D. Synthesis of Thiopyrano[2,3-d]pyrimidines; (1) From Pyrimidines; (2) From Thiopyrans; E. Synthesis of Thiopyrano[3,4-d]pyrimidines
F. Synthesis of Thiopyrano[4,3-d]pyrimidines3. Reactions; A. With Nucleophilic Reagents; B. Other Reactions; 4. Patent Literature; 5. Tables; Table 1. The Pyrano[2,3-d]pyrimidines; Table 2. The Pyrano[4,3-d]pyrimidines; Table 3. Miscellaneous Pyranopyrimidines; Table 4. The Thiopyrano[2,3-d]pyrimidines; Table 5. The Thiopyrano[3,4-d]pyrimidines; 6. References; CHAPTER III. PYRIMIDOPYRIMIDINES; 1. Nomenclature; 2. Methods of Synthesis of the Ring System; A. Synthesis of Pyrimido[4,5-d]pyrimidines; (1) From Pyrimidines with Amino Groups Adjacent to Hydrogen
(2) From Pyrimidines with Amino Groups Adjacent to Nitriles
Record Nr. UNINA-9910840726203321
Delia Thomas J  
New York, : Interscience Publishers, 1992
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Fused pyrimidines . Part two [[electronic resource] /] / edited by D. J. Brown
Fused pyrimidines . Part two [[electronic resource] /] / edited by D. J. Brown
Autore Lister John H (John Henry)
Edizione [99th ed.]
Pubbl/distr/stampa New York, : Wiley-Interscience, 1971
Descrizione fisica 1 online resource (684 p.)
Disciplina 547.593
547/.59/05
547/.596
Altri autori (Persone) BrownD. J
Collana Chemistry of heterocyclic compounds
Soggetto topico Pyrimidines
Chemistry
ISBN 1-282-30164-0
9786612301643
0-470-18688-7
0-470-18836-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto FUSED PYRIMIDINES: PURINES; Contents; Tables; I. Introduction to the Purines; 1. History; TABLE 1. Trivial Names of Purines; 2. Nomenclature and Notation; 3. The Basis of Purine Chemistry; A. The Electrophilic Character of the 2-, 6- and 8-Carbon Atoms; B. The Nucleophilic Character of the 8-Carbon Atom; C. Tautomeric Groups; 4. General Summary of Purine Chemistry; A. Electrophilic Substitution; (a) Nitration; (b) Diazo Coupling; (c) Halogenation; (d) Alkylation; B. Nucleophilic Substitution; (a) Halogen Replacement by Amino Groups; (b) Halogen Replacement by Methoxy and Other Alkoxy Groups
(c) Halogen Replacement by Oxo Group(d) Halogen Replacement by Alkylthio Groups; (e) Halogen Replacement by Thio Group; (f) Halogen Replacement by Thiocyanato and Cyano Groups; (g) Halogen Replacement by Sulpho Groups; (h) Replacement of Methoxy, Methylthio, and Methylsulphonyl Groups; C. Group Interconversion; (a) Interchange of Halogen Atoms; (b) Oxo- to Aminopurines; (c) Oxo- to Chloropurines; (d) Oxo- to Thiopurines; (e) Thio- (and Methylthio-) to Oxopurines; (f) Thio- (and Methylthio-) to Halogenopurines; (g) Thio- to Aminopurines; (h) Interchange of Amino Groups
(i) Amino- to Oxopurines(j) Amino- to Halogenopurines; D. Addition Reactions; (a) The Michael Reaction; (b) Quaternisation; (c) Formation of N-Oxides; (d) Addition of Water and Alcohols; E. Modification of Substituents; (a) Amino Groups; (b) Oxo Groups; (c) Thio Groups; (d) Methyl Groups; F. Reductive Reactions; (a) Nuclear Reduction; (b) Removal of Groups; (c) Reductive Modification of Groups; G. Oxidative Reactions; (a) Chemical Oxidation; (b) Free Radical Attack; (c) Enzymic Oxidation; 5. Physical Properties of Purines; A. Electronic Considerations; B. Ionisation Constants
C. Crystal StructureD. Dipole Moments; E. Polarography; F. Solubility and Melting Point; G. Spectra; Chapter II. Syntheses from Pyrimidines; 1. Use of 4,5-Diaminopyrimidines (The Traube Synthesis); A. History and General Application; B. Cyclisation with Formic Acid; C. Cyclisation with Dithioformic Acid; D. Cyclisation with Other Carboxylic Acids; E. Cyclisation with Acid Anhydride; F. Cyclisation with Acid Chlorides; G. Cyclisation with Orthoesters and Diethoxymethyl Acetate
TABLE 2. Cyclisation of 4,5-Diamino-6-dimethylamino-2-methylthiopyrimidine to 6-dimethylamino-2-methylthiopurine with OrthoestersH. Cyclisation with Formamide; I. Cyclisation with Other Amides; J. Cyclisation with NN-Dialkylamides and Phosphoryl Chloride; K. Cyclisation with Amidines; L. Cyclisation with Guanidines; M. Cyclisation with Urea; N. Cyclisation with Thiourea; O. Cyclisation with Cyanates, Isocyanates, and Derivatives; P. Cyclisation with lsothiocyanates; Q. Cyclisation with Carbon Dioxide; R. Cyclisation with Carbon Disulphide; S. Cyclisation with Phosgene
T. Cyclisation with Thiophosgene
Record Nr. UNINA-9910144283103321
Lister John H (John Henry)  
New York, : Wiley-Interscience, 1971
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Fused pyrimidines . Part two [[electronic resource] /] / edited by D. J. Brown
Fused pyrimidines . Part two [[electronic resource] /] / edited by D. J. Brown
Autore Lister John H (John Henry)
Edizione [99th ed.]
Pubbl/distr/stampa New York, : Wiley-Interscience, 1971
Descrizione fisica 1 online resource (684 p.)
Disciplina 547.593
547/.59/05
547/.596
Altri autori (Persone) BrownD. J
Collana Chemistry of heterocyclic compounds
Soggetto topico Pyrimidines
Chemistry
ISBN 1-282-30164-0
9786612301643
0-470-18688-7
0-470-18836-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto FUSED PYRIMIDINES: PURINES; Contents; Tables; I. Introduction to the Purines; 1. History; TABLE 1. Trivial Names of Purines; 2. Nomenclature and Notation; 3. The Basis of Purine Chemistry; A. The Electrophilic Character of the 2-, 6- and 8-Carbon Atoms; B. The Nucleophilic Character of the 8-Carbon Atom; C. Tautomeric Groups; 4. General Summary of Purine Chemistry; A. Electrophilic Substitution; (a) Nitration; (b) Diazo Coupling; (c) Halogenation; (d) Alkylation; B. Nucleophilic Substitution; (a) Halogen Replacement by Amino Groups; (b) Halogen Replacement by Methoxy and Other Alkoxy Groups
(c) Halogen Replacement by Oxo Group(d) Halogen Replacement by Alkylthio Groups; (e) Halogen Replacement by Thio Group; (f) Halogen Replacement by Thiocyanato and Cyano Groups; (g) Halogen Replacement by Sulpho Groups; (h) Replacement of Methoxy, Methylthio, and Methylsulphonyl Groups; C. Group Interconversion; (a) Interchange of Halogen Atoms; (b) Oxo- to Aminopurines; (c) Oxo- to Chloropurines; (d) Oxo- to Thiopurines; (e) Thio- (and Methylthio-) to Oxopurines; (f) Thio- (and Methylthio-) to Halogenopurines; (g) Thio- to Aminopurines; (h) Interchange of Amino Groups
(i) Amino- to Oxopurines(j) Amino- to Halogenopurines; D. Addition Reactions; (a) The Michael Reaction; (b) Quaternisation; (c) Formation of N-Oxides; (d) Addition of Water and Alcohols; E. Modification of Substituents; (a) Amino Groups; (b) Oxo Groups; (c) Thio Groups; (d) Methyl Groups; F. Reductive Reactions; (a) Nuclear Reduction; (b) Removal of Groups; (c) Reductive Modification of Groups; G. Oxidative Reactions; (a) Chemical Oxidation; (b) Free Radical Attack; (c) Enzymic Oxidation; 5. Physical Properties of Purines; A. Electronic Considerations; B. Ionisation Constants
C. Crystal StructureD. Dipole Moments; E. Polarography; F. Solubility and Melting Point; G. Spectra; Chapter II. Syntheses from Pyrimidines; 1. Use of 4,5-Diaminopyrimidines (The Traube Synthesis); A. History and General Application; B. Cyclisation with Formic Acid; C. Cyclisation with Dithioformic Acid; D. Cyclisation with Other Carboxylic Acids; E. Cyclisation with Acid Anhydride; F. Cyclisation with Acid Chlorides; G. Cyclisation with Orthoesters and Diethoxymethyl Acetate
TABLE 2. Cyclisation of 4,5-Diamino-6-dimethylamino-2-methylthiopyrimidine to 6-dimethylamino-2-methylthiopurine with OrthoestersH. Cyclisation with Formamide; I. Cyclisation with Other Amides; J. Cyclisation with NN-Dialkylamides and Phosphoryl Chloride; K. Cyclisation with Amidines; L. Cyclisation with Guanidines; M. Cyclisation with Urea; N. Cyclisation with Thiourea; O. Cyclisation with Cyanates, Isocyanates, and Derivatives; P. Cyclisation with lsothiocyanates; Q. Cyclisation with Carbon Dioxide; R. Cyclisation with Carbon Disulphide; S. Cyclisation with Phosgene
T. Cyclisation with Thiophosgene
Record Nr. UNINA-9910830142903321
Lister John H (John Henry)  
New York, : Wiley-Interscience, 1971
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Fused pyrimidines . Part two [[electronic resource] /] / edited by D. J. Brown
Fused pyrimidines . Part two [[electronic resource] /] / edited by D. J. Brown
Autore Lister John H (John Henry)
Edizione [99th ed.]
Pubbl/distr/stampa New York, : Wiley-Interscience, 1971
Descrizione fisica 1 online resource (684 p.)
Disciplina 547.593
547/.59/05
547/.596
Altri autori (Persone) BrownD. J
Collana Chemistry of heterocyclic compounds
Soggetto topico Pyrimidines
Chemistry
ISBN 1-282-30164-0
9786612301643
0-470-18688-7
0-470-18836-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto FUSED PYRIMIDINES: PURINES; Contents; Tables; I. Introduction to the Purines; 1. History; TABLE 1. Trivial Names of Purines; 2. Nomenclature and Notation; 3. The Basis of Purine Chemistry; A. The Electrophilic Character of the 2-, 6- and 8-Carbon Atoms; B. The Nucleophilic Character of the 8-Carbon Atom; C. Tautomeric Groups; 4. General Summary of Purine Chemistry; A. Electrophilic Substitution; (a) Nitration; (b) Diazo Coupling; (c) Halogenation; (d) Alkylation; B. Nucleophilic Substitution; (a) Halogen Replacement by Amino Groups; (b) Halogen Replacement by Methoxy and Other Alkoxy Groups
(c) Halogen Replacement by Oxo Group(d) Halogen Replacement by Alkylthio Groups; (e) Halogen Replacement by Thio Group; (f) Halogen Replacement by Thiocyanato and Cyano Groups; (g) Halogen Replacement by Sulpho Groups; (h) Replacement of Methoxy, Methylthio, and Methylsulphonyl Groups; C. Group Interconversion; (a) Interchange of Halogen Atoms; (b) Oxo- to Aminopurines; (c) Oxo- to Chloropurines; (d) Oxo- to Thiopurines; (e) Thio- (and Methylthio-) to Oxopurines; (f) Thio- (and Methylthio-) to Halogenopurines; (g) Thio- to Aminopurines; (h) Interchange of Amino Groups
(i) Amino- to Oxopurines(j) Amino- to Halogenopurines; D. Addition Reactions; (a) The Michael Reaction; (b) Quaternisation; (c) Formation of N-Oxides; (d) Addition of Water and Alcohols; E. Modification of Substituents; (a) Amino Groups; (b) Oxo Groups; (c) Thio Groups; (d) Methyl Groups; F. Reductive Reactions; (a) Nuclear Reduction; (b) Removal of Groups; (c) Reductive Modification of Groups; G. Oxidative Reactions; (a) Chemical Oxidation; (b) Free Radical Attack; (c) Enzymic Oxidation; 5. Physical Properties of Purines; A. Electronic Considerations; B. Ionisation Constants
C. Crystal StructureD. Dipole Moments; E. Polarography; F. Solubility and Melting Point; G. Spectra; Chapter II. Syntheses from Pyrimidines; 1. Use of 4,5-Diaminopyrimidines (The Traube Synthesis); A. History and General Application; B. Cyclisation with Formic Acid; C. Cyclisation with Dithioformic Acid; D. Cyclisation with Other Carboxylic Acids; E. Cyclisation with Acid Anhydride; F. Cyclisation with Acid Chlorides; G. Cyclisation with Orthoesters and Diethoxymethyl Acetate
TABLE 2. Cyclisation of 4,5-Diamino-6-dimethylamino-2-methylthiopyrimidine to 6-dimethylamino-2-methylthiopurine with OrthoestersH. Cyclisation with Formamide; I. Cyclisation with Other Amides; J. Cyclisation with NN-Dialkylamides and Phosphoryl Chloride; K. Cyclisation with Amidines; L. Cyclisation with Guanidines; M. Cyclisation with Urea; N. Cyclisation with Thiourea; O. Cyclisation with Cyanates, Isocyanates, and Derivatives; P. Cyclisation with lsothiocyanates; Q. Cyclisation with Carbon Dioxide; R. Cyclisation with Carbon Disulphide; S. Cyclisation with Phosgene
T. Cyclisation with Thiophosgene
Record Nr. UNINA-9910841669103321
Lister John H (John Henry)  
New York, : Wiley-Interscience, 1971
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui