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The pulmonary endothelium [[electronic resource] /] / [edited by] Norbert F. Voelkel, Sharon Rounds
| The pulmonary endothelium [[electronic resource] /] / [edited by] Norbert F. Voelkel, Sharon Rounds |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley & Sons, 2009 |
| Descrizione fisica | 1 online resource (549 p.) |
| Disciplina | 612.2 |
| Altri autori (Persone) |
VoelkelNorbert F
RoundsSharon <1946-> |
| Soggetto topico |
Pulmonary endothelium
Pulmonary endothelium - Pathophysiology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-29166-1
9786612291661 0-470-74749-8 0-470-74750-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Pulmonary Endothelium; Contents; List of Contributors; Introduction; SECTION I: NORMAL PULMONARY ENDOTHELIUM. STRUCTURE, FUNCTION, CELL BIOLOGY; 1: Development of the Pulmonary Endothelium in Development of the Pulmonary Circulation: Vasculogenesis and Angiogenesis; 2: Anatomy of the Pulmonary Endothelium; 3: Cadherins and Connexins in Pulmonary Endothelial Function; 4: Pulmonary Endothelial Cell Interactions with the Extracellular Matrix; 5: Pulmonary Endothelial Cell Calcium Signaling and Regulation of Lung Vascular Barrier Function; 6: Pulmonary Endothelium and Nitric Oxide
7: Pulmonary Endothelial Cell Surface Metabolic Functions8: Cell Biology of Lung Endothelial Permeability; 9: Lung Endothelial Phenotypes: Insights Derived from the Systematic Study of Calcium Channels; 10: Pulmonary Endothelial Interactions with Leukocytes and Platelets; 11: Mesenchymal-Endothelial Interactions in the Control of Angiogenic, Inflammatory, and Fibrotic Responses in the Pulmonary Circulation; 12: Pulmonary Endothelium and Vasomotor Control; 13: Pulmonary Endothelial Progenitor Cells; 14: Bronchial Vasculature: The Other Pulmonary Circulation 15: Mapping Protein Expression on Pulmonary Vascular EndotheliumSECTION II: MECHANISMS AND CONSEQUENCES OF PULMONARY ENDOTHELIAL CELL INJURY; 16: Pulmonary Endothelial Cell Death: Implications for Lung Disease Pathogenesis; 17: Oxidant-Mediated Signaling and Injury in Pulmonary Endothelium; 18: Hypoxia and the Pulmonary Endothelium; 19: Viral Infection and Pulmonary Endothelial Cells; 20: Effects of Pressure and Flow on the Pulmonary Endothelium; 21: Therapeutic Strategies to Limit Lung Endothelial Cell Permeability; 22: Targeted Delivery of Biotherapeutics to the Pulmonary Endothelium SECTION III:PULMONARY ENDOTHELIUM IN DISEASE23: Endothelial Regulation of the Pulmonary Circulation in the Fetus and Newborn; 24: Genetic Insights into Endothelial Barrier Regulation in the Acutely Inflamed Lung; 25: Interactions of Pulmonary Endothelial Cells with Immune Cells and Platelets: Implications for Disease Pathogenesis; 26: Role of the Endothelium in Emphysema: Emphysema - A Lung Microvascular Disease; 27: Pulmonary Endothelium and Pulmonary Hypertension; 28: Collagen Vascular Diseases and Pulmonary Endothelium; 29: Pulmonary Endothelium in Thromboembolism 30: Pulmonary Endothelium and MalignanciesEpilogue; Index |
| Record Nr. | UNINA-9910139765003321 |
| Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley & Sons, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The pulmonary endothelium [[electronic resource] /] / [edited by] Norbert F. Voelkel, Sharon Rounds
| The pulmonary endothelium [[electronic resource] /] / [edited by] Norbert F. Voelkel, Sharon Rounds |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley & Sons, 2009 |
| Descrizione fisica | 1 online resource (549 p.) |
| Disciplina | 612.2 |
| Altri autori (Persone) |
VoelkelNorbert F
RoundsSharon <1946-> |
| Soggetto topico |
Pulmonary endothelium
Pulmonary endothelium - Pathophysiology |
| ISBN |
1-282-29166-1
9786612291661 0-470-74749-8 0-470-74750-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Pulmonary Endothelium; Contents; List of Contributors; Introduction; SECTION I: NORMAL PULMONARY ENDOTHELIUM. STRUCTURE, FUNCTION, CELL BIOLOGY; 1: Development of the Pulmonary Endothelium in Development of the Pulmonary Circulation: Vasculogenesis and Angiogenesis; 2: Anatomy of the Pulmonary Endothelium; 3: Cadherins and Connexins in Pulmonary Endothelial Function; 4: Pulmonary Endothelial Cell Interactions with the Extracellular Matrix; 5: Pulmonary Endothelial Cell Calcium Signaling and Regulation of Lung Vascular Barrier Function; 6: Pulmonary Endothelium and Nitric Oxide
7: Pulmonary Endothelial Cell Surface Metabolic Functions8: Cell Biology of Lung Endothelial Permeability; 9: Lung Endothelial Phenotypes: Insights Derived from the Systematic Study of Calcium Channels; 10: Pulmonary Endothelial Interactions with Leukocytes and Platelets; 11: Mesenchymal-Endothelial Interactions in the Control of Angiogenic, Inflammatory, and Fibrotic Responses in the Pulmonary Circulation; 12: Pulmonary Endothelium and Vasomotor Control; 13: Pulmonary Endothelial Progenitor Cells; 14: Bronchial Vasculature: The Other Pulmonary Circulation 15: Mapping Protein Expression on Pulmonary Vascular EndotheliumSECTION II: MECHANISMS AND CONSEQUENCES OF PULMONARY ENDOTHELIAL CELL INJURY; 16: Pulmonary Endothelial Cell Death: Implications for Lung Disease Pathogenesis; 17: Oxidant-Mediated Signaling and Injury in Pulmonary Endothelium; 18: Hypoxia and the Pulmonary Endothelium; 19: Viral Infection and Pulmonary Endothelial Cells; 20: Effects of Pressure and Flow on the Pulmonary Endothelium; 21: Therapeutic Strategies to Limit Lung Endothelial Cell Permeability; 22: Targeted Delivery of Biotherapeutics to the Pulmonary Endothelium SECTION III:PULMONARY ENDOTHELIUM IN DISEASE23: Endothelial Regulation of the Pulmonary Circulation in the Fetus and Newborn; 24: Genetic Insights into Endothelial Barrier Regulation in the Acutely Inflamed Lung; 25: Interactions of Pulmonary Endothelial Cells with Immune Cells and Platelets: Implications for Disease Pathogenesis; 26: Role of the Endothelium in Emphysema: Emphysema - A Lung Microvascular Disease; 27: Pulmonary Endothelium and Pulmonary Hypertension; 28: Collagen Vascular Diseases and Pulmonary Endothelium; 29: Pulmonary Endothelium in Thromboembolism 30: Pulmonary Endothelium and MalignanciesEpilogue; Index |
| Record Nr. | UNINA-9910830605903321 |
| Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley & Sons, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The pulmonary endothelium [[electronic resource] /] / [edited by] Norbert F. Voelkel, Sharon Rounds
| The pulmonary endothelium [[electronic resource] /] / [edited by] Norbert F. Voelkel, Sharon Rounds |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley & Sons, 2009 |
| Descrizione fisica | 1 online resource (549 p.) |
| Disciplina | 612.2 |
| Altri autori (Persone) |
VoelkelNorbert F
RoundsSharon <1946-> |
| Soggetto topico |
Pulmonary endothelium
Pulmonary endothelium - Pathophysiology |
| ISBN |
1-282-29166-1
9786612291661 0-470-74749-8 0-470-74750-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Pulmonary Endothelium; Contents; List of Contributors; Introduction; SECTION I: NORMAL PULMONARY ENDOTHELIUM. STRUCTURE, FUNCTION, CELL BIOLOGY; 1: Development of the Pulmonary Endothelium in Development of the Pulmonary Circulation: Vasculogenesis and Angiogenesis; 2: Anatomy of the Pulmonary Endothelium; 3: Cadherins and Connexins in Pulmonary Endothelial Function; 4: Pulmonary Endothelial Cell Interactions with the Extracellular Matrix; 5: Pulmonary Endothelial Cell Calcium Signaling and Regulation of Lung Vascular Barrier Function; 6: Pulmonary Endothelium and Nitric Oxide
7: Pulmonary Endothelial Cell Surface Metabolic Functions8: Cell Biology of Lung Endothelial Permeability; 9: Lung Endothelial Phenotypes: Insights Derived from the Systematic Study of Calcium Channels; 10: Pulmonary Endothelial Interactions with Leukocytes and Platelets; 11: Mesenchymal-Endothelial Interactions in the Control of Angiogenic, Inflammatory, and Fibrotic Responses in the Pulmonary Circulation; 12: Pulmonary Endothelium and Vasomotor Control; 13: Pulmonary Endothelial Progenitor Cells; 14: Bronchial Vasculature: The Other Pulmonary Circulation 15: Mapping Protein Expression on Pulmonary Vascular EndotheliumSECTION II: MECHANISMS AND CONSEQUENCES OF PULMONARY ENDOTHELIAL CELL INJURY; 16: Pulmonary Endothelial Cell Death: Implications for Lung Disease Pathogenesis; 17: Oxidant-Mediated Signaling and Injury in Pulmonary Endothelium; 18: Hypoxia and the Pulmonary Endothelium; 19: Viral Infection and Pulmonary Endothelial Cells; 20: Effects of Pressure and Flow on the Pulmonary Endothelium; 21: Therapeutic Strategies to Limit Lung Endothelial Cell Permeability; 22: Targeted Delivery of Biotherapeutics to the Pulmonary Endothelium SECTION III:PULMONARY ENDOTHELIUM IN DISEASE23: Endothelial Regulation of the Pulmonary Circulation in the Fetus and Newborn; 24: Genetic Insights into Endothelial Barrier Regulation in the Acutely Inflamed Lung; 25: Interactions of Pulmonary Endothelial Cells with Immune Cells and Platelets: Implications for Disease Pathogenesis; 26: Role of the Endothelium in Emphysema: Emphysema - A Lung Microvascular Disease; 27: Pulmonary Endothelium and Pulmonary Hypertension; 28: Collagen Vascular Diseases and Pulmonary Endothelium; 29: Pulmonary Endothelium in Thromboembolism 30: Pulmonary Endothelium and MalignanciesEpilogue; Index |
| Record Nr. | UNINA-9910841179503321 |
| Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley & Sons, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The pulmonary epithelium in health and disease [[electronic resource] /] / edited by David Proud
| The pulmonary epithelium in health and disease [[electronic resource] /] / edited by David Proud |
| Pubbl/distr/stampa | Chichester, England ; ; Hoboken, NJ, : John Wiley & Sons, c2008 |
| Descrizione fisica | 1 online resource (461 p.) |
| Disciplina | 616.2 |
| Altri autori (Persone) | ProudDavid |
| Soggetto topico |
Respiratory organs - Pathophysiology
Pulmonary endothelium Epithelium |
| ISBN |
1-282-34293-2
9786612342936 0-470-72701-2 0-470-72700-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Pulmonary Epithelium in Health and Disease; Contents; Preface; List of Contributors; 1 Pulmonary Epithelium: Cell Types and Functions; 1.1 Introduction; 1.2 Epithelial cell types and functions in the cartilaginous proximal airway region; 1.3 Epithelial cell types and functions of the non-cartilaginous distal bronchioles; 1.4 Epithelial cell types and functions of the gas exchange region; 1.5 Circulating stem cells and applications in lung regenerative medicine; 1.6 Stem cell therapy: embryonic or adult?; 1.7 Conclusion; 2 Epithelial Adhesive Structures and Adhesion Molecule Expression
2.1 Introduction2.2 Cell-cell adhesive structures; 2.3 Cell-substratum adhesion; 2.4 Conclusion; 3 The Epithelium as a Target; 3.1 Introduction; 3.2 Asthma; 3.3 Alteration in epithelial cell type distribution; 3.4 Overview of epithelial damage in asthma; 3.5 Chronic obstructive pulmonary disease; 3.6 Effect of cigarette smoke; 3.7 Other causative factors; 3.8 Alveolar epithelial cell apoptosis - emphysema; 3.9 Overview of epithelial damage in COPD; 3.10 Damage to the epithelium in other diseases; 3.11 Conclusions; 4 Epithelial Repair and Function 4.1 Brief introduction to epithelial shedding-repair and associated functions in health and disease4.2 Repair following shedding of single columnar epithelial cells and following shedding of clusters of columnar cells; 4.3 Epithelial denudation; 4.4 Pharmacology of epithelial repair; 4.5 Epithelial shedding-restitution as a causative process in airway inflammation and remodelling; 5 Integration of Epithelial Ion Transport Activities into Airway Surface Liquid Volume and Ion Composition Regulation; 5.1 Introduction: the role of fluid in airway/ alveolar physiology 5.2 Model of ion and solute transport through airway epithelia5.3 Airway histology; 5.4 Airway ion secretion; 5.5 The cystic fibrosis transmembrane conductance regulator; 5.6 Calcium-activated chloride channels; 5.7 K+ channels; 5.8 Airway ion absorption; 5.9 Measurement of ion and water transport in airway epithelia; 5.10 In vivo transepithelial PDs; 5.11 Volume flow measurements; 5.12 Physiologically 'thin film' measurements of ASL volume regulation with confocal microscopy and microelectrodes: studies of normal and CF airway epithelia 5.13 The role of physiologic airway shear-stress in ion transport and ASL regulation5.14 Fluid transport across the alveolar epithelium; 6 Structure and Function of Cilia; 6.1 Introduction; 6.2 Structure; 6.3 Function; 6.4 Ciliary dysfunction associated with disease; 7 Composition and Function of Airway Mucus; 7.1 Airway 'mucus'; 7.2 Respiratory tract mucins; 7.3 Mucin genes and gene products; 7.4 MUC5AC; 7.5 MUC5B; 7.6 Airway mucus hypersecretory phenotype in COPD; 7.7 Airway mucus hypersecretory phenotype in asthma; 7.8 Mucociliary clearance in asthma and COPD 7.9 Mechanisms of airway goblet cell hyperplasia |
| Record Nr. | UNINA-9910144698303321 |
| Chichester, England ; ; Hoboken, NJ, : John Wiley & Sons, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The pulmonary epithelium in health and disease [[electronic resource] /] / edited by David Proud
| The pulmonary epithelium in health and disease [[electronic resource] /] / edited by David Proud |
| Pubbl/distr/stampa | Chichester, England ; ; Hoboken, NJ, : John Wiley & Sons, c2008 |
| Descrizione fisica | 1 online resource (461 p.) |
| Disciplina | 616.2 |
| Altri autori (Persone) | ProudDavid |
| Soggetto topico |
Respiratory organs - Pathophysiology
Pulmonary endothelium Epithelium |
| ISBN |
1-282-34293-2
9786612342936 0-470-72701-2 0-470-72700-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Pulmonary Epithelium in Health and Disease; Contents; Preface; List of Contributors; 1 Pulmonary Epithelium: Cell Types and Functions; 1.1 Introduction; 1.2 Epithelial cell types and functions in the cartilaginous proximal airway region; 1.3 Epithelial cell types and functions of the non-cartilaginous distal bronchioles; 1.4 Epithelial cell types and functions of the gas exchange region; 1.5 Circulating stem cells and applications in lung regenerative medicine; 1.6 Stem cell therapy: embryonic or adult?; 1.7 Conclusion; 2 Epithelial Adhesive Structures and Adhesion Molecule Expression
2.1 Introduction2.2 Cell-cell adhesive structures; 2.3 Cell-substratum adhesion; 2.4 Conclusion; 3 The Epithelium as a Target; 3.1 Introduction; 3.2 Asthma; 3.3 Alteration in epithelial cell type distribution; 3.4 Overview of epithelial damage in asthma; 3.5 Chronic obstructive pulmonary disease; 3.6 Effect of cigarette smoke; 3.7 Other causative factors; 3.8 Alveolar epithelial cell apoptosis - emphysema; 3.9 Overview of epithelial damage in COPD; 3.10 Damage to the epithelium in other diseases; 3.11 Conclusions; 4 Epithelial Repair and Function 4.1 Brief introduction to epithelial shedding-repair and associated functions in health and disease4.2 Repair following shedding of single columnar epithelial cells and following shedding of clusters of columnar cells; 4.3 Epithelial denudation; 4.4 Pharmacology of epithelial repair; 4.5 Epithelial shedding-restitution as a causative process in airway inflammation and remodelling; 5 Integration of Epithelial Ion Transport Activities into Airway Surface Liquid Volume and Ion Composition Regulation; 5.1 Introduction: the role of fluid in airway/ alveolar physiology 5.2 Model of ion and solute transport through airway epithelia5.3 Airway histology; 5.4 Airway ion secretion; 5.5 The cystic fibrosis transmembrane conductance regulator; 5.6 Calcium-activated chloride channels; 5.7 K+ channels; 5.8 Airway ion absorption; 5.9 Measurement of ion and water transport in airway epithelia; 5.10 In vivo transepithelial PDs; 5.11 Volume flow measurements; 5.12 Physiologically 'thin film' measurements of ASL volume regulation with confocal microscopy and microelectrodes: studies of normal and CF airway epithelia 5.13 The role of physiologic airway shear-stress in ion transport and ASL regulation5.14 Fluid transport across the alveolar epithelium; 6 Structure and Function of Cilia; 6.1 Introduction; 6.2 Structure; 6.3 Function; 6.4 Ciliary dysfunction associated with disease; 7 Composition and Function of Airway Mucus; 7.1 Airway 'mucus'; 7.2 Respiratory tract mucins; 7.3 Mucin genes and gene products; 7.4 MUC5AC; 7.5 MUC5B; 7.6 Airway mucus hypersecretory phenotype in COPD; 7.7 Airway mucus hypersecretory phenotype in asthma; 7.8 Mucociliary clearance in asthma and COPD 7.9 Mechanisms of airway goblet cell hyperplasia |
| Record Nr. | UNINA-9910806300303321 |
| Chichester, England ; ; Hoboken, NJ, : John Wiley & Sons, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
