Bacterial and eukaryotic porins [[electronic resource] ] : structure, function, mechanism / / edited by Roland Benz |
Pubbl/distr/stampa | Weinheim [Germany], : Wiley-VCH, c2004 |
Descrizione fisica | 1 online resource (388 p.) |
Disciplina | 572.6 |
Altri autori (Persone) | BenzRoland <1943-> |
Soggetto topico |
Molecules
Proteins - Structure |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-51962-2
9786610519620 3-527-60387-5 3-527-60422-7 |
Classificazione | 42.15 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Bacterial and Eukaryotic Porins; Contents; Preface; References; List of Contributors; 1 Regulation of Porin Gene Expression by the Two-component Regulatory System EnvZ/OmpR; 1.1 Introduction; 1.2 The Structure of EnvZ; 1.3 Biochemical Activities of EnvZ underlie Signaling; 1.4 What is the EnvZ Activity Regulated by the Stimulus?; 1.5 How is the Signal Propagated?; 1.6 Is there a Role for Acetyl-phosphate in OmpR-P Production?; 1.7 The OmpR Subfamily; 1.8 OmpR Binding Sites; 1.9 Recruitment of RNA Polymerase to OmpR-dependent Promoters; 1.10 OmpR-RNAP Interaction Surface
1.11 Affinity Model of Porin Gene Regulation1.12 A Test of the Affinity Model; 1.13 Conformational Changes in OmpR Contribute to Differential Regulation of the Porin Genes; 1.14 Other Factors that Regulate ompF and ompC; 1.15 OmpR is a Global Regulator; 1.15.1 Flagellar Biosynthesis; 1.15.2 Curli Fimbriae Production; 1.15.3 Virulence; Acknowledgments; References; 2 The Structures of General Porins; 2.1 Bacterial Outer Membrane Proteins; 2.2 Construction of General Porins; 2.3 Trimer Association and Folding; 2.4 Pore Geometry; 2.5 Permeation; 2.6 Conclusion; Acknowledgments; References 3 Role of Bacterial Porins in Antibiotic Susceptibility of Gram-negative Bacteria3.1 Introduction; 3.2 Role of Porins in Antibiotic Resistance; 3.2.1 Evolution of Clinical Isolates; 3.2.2 Expression of a Modified Porin; 3.3 In Vitro Mutagenesis Analyses of Porins and Modeling; 3.3.1 Mutations in the Loop 3 Domain; 3.3.2 Mutations in the Anti-loop 3 Domain; 3.3.3 Modeling of β-Lactam in the OmpF Eyelet; 3.4 Conclusion; Acknowledgments; References; 4 Porins of the Outer Membrane of Pseudomonas aeruginosa; 4.1 Introduction; 4.2 The Outer Membrane Permeability Defect in P. aeruginosa 4.3 Porins Identified in the Genome Sequence4.4 The General Porins; 4.4.1 OprF; 4.4.2 Other General Porins; 4.5 Efflux; 4.5.1 OprM; 4.5.2 OprM Homologs; 4.6 Specific Porins; 4.6.1 OprB; 4.6.2 OprP and OprO; 4.6.3 OprD; 4.6.4 OprD Homologs; 4.7 TonB-dependent Receptors; 4.7.1 FpvA; 4.7.2 FptA; 4.7.3 PfeA and PirA; 4.7.4 HasR, PhuR and OptI; 4.7.5 Other TonB-dependent Receptors; 4.8 Conclusions; Acknowledgments; References; 5 Regulation of Bacterial Porin Function; 5.1 Introduction; 5.2 Voltage Dependence; 5.2.1 L3 and the Constriction Zone; 5.2.2 Extracellular Loops 5.2.3 Modulation of Voltage Gating5.3 Effect of pH; 5.4 Polyamine Modulation; 5.5 Others; 5.6 Concluding Remarks; Acknowledgements; References; 6 Reconstitution of General Diffusion Pores from Bacterial Outer Membranes; 6.1 Introduction; 6.2 Planar Lipid Bilayer Technique; 6.3 Intrinsic Properties of General Diffusion Channels; 6.3.1 Single-channel Analysis of OmpF Gating; 6.3.2 Molecular Origin of Voltage Gating; 6.3.3 Effect of Membrane Composition and OmpF-LPS Interactions; 6.3.4 Open-channel Conductance; 6.3.5 Voltage Effect and Channel Orientation; 6.3.6 Ion Selectivity 6.3.7 The Permeating Cations Interact with Specific Elements along the Ionic Pathway |
Record Nr. | UNINA-9910143966303321 |
Weinheim [Germany], : Wiley-VCH, c2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Bacterial and eukaryotic porins [[electronic resource] ] : structure, function, mechanism / / edited by Roland Benz |
Pubbl/distr/stampa | Weinheim [Germany], : Wiley-VCH, c2004 |
Descrizione fisica | 1 online resource (388 p.) |
Disciplina | 572.6 |
Altri autori (Persone) | BenzRoland <1943-> |
Soggetto topico |
Molecules
Proteins - Structure |
ISBN |
1-280-51962-2
9786610519620 3-527-60387-5 3-527-60422-7 |
Classificazione | 42.15 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Bacterial and Eukaryotic Porins; Contents; Preface; References; List of Contributors; 1 Regulation of Porin Gene Expression by the Two-component Regulatory System EnvZ/OmpR; 1.1 Introduction; 1.2 The Structure of EnvZ; 1.3 Biochemical Activities of EnvZ underlie Signaling; 1.4 What is the EnvZ Activity Regulated by the Stimulus?; 1.5 How is the Signal Propagated?; 1.6 Is there a Role for Acetyl-phosphate in OmpR-P Production?; 1.7 The OmpR Subfamily; 1.8 OmpR Binding Sites; 1.9 Recruitment of RNA Polymerase to OmpR-dependent Promoters; 1.10 OmpR-RNAP Interaction Surface
1.11 Affinity Model of Porin Gene Regulation1.12 A Test of the Affinity Model; 1.13 Conformational Changes in OmpR Contribute to Differential Regulation of the Porin Genes; 1.14 Other Factors that Regulate ompF and ompC; 1.15 OmpR is a Global Regulator; 1.15.1 Flagellar Biosynthesis; 1.15.2 Curli Fimbriae Production; 1.15.3 Virulence; Acknowledgments; References; 2 The Structures of General Porins; 2.1 Bacterial Outer Membrane Proteins; 2.2 Construction of General Porins; 2.3 Trimer Association and Folding; 2.4 Pore Geometry; 2.5 Permeation; 2.6 Conclusion; Acknowledgments; References 3 Role of Bacterial Porins in Antibiotic Susceptibility of Gram-negative Bacteria3.1 Introduction; 3.2 Role of Porins in Antibiotic Resistance; 3.2.1 Evolution of Clinical Isolates; 3.2.2 Expression of a Modified Porin; 3.3 In Vitro Mutagenesis Analyses of Porins and Modeling; 3.3.1 Mutations in the Loop 3 Domain; 3.3.2 Mutations in the Anti-loop 3 Domain; 3.3.3 Modeling of β-Lactam in the OmpF Eyelet; 3.4 Conclusion; Acknowledgments; References; 4 Porins of the Outer Membrane of Pseudomonas aeruginosa; 4.1 Introduction; 4.2 The Outer Membrane Permeability Defect in P. aeruginosa 4.3 Porins Identified in the Genome Sequence4.4 The General Porins; 4.4.1 OprF; 4.4.2 Other General Porins; 4.5 Efflux; 4.5.1 OprM; 4.5.2 OprM Homologs; 4.6 Specific Porins; 4.6.1 OprB; 4.6.2 OprP and OprO; 4.6.3 OprD; 4.6.4 OprD Homologs; 4.7 TonB-dependent Receptors; 4.7.1 FpvA; 4.7.2 FptA; 4.7.3 PfeA and PirA; 4.7.4 HasR, PhuR and OptI; 4.7.5 Other TonB-dependent Receptors; 4.8 Conclusions; Acknowledgments; References; 5 Regulation of Bacterial Porin Function; 5.1 Introduction; 5.2 Voltage Dependence; 5.2.1 L3 and the Constriction Zone; 5.2.2 Extracellular Loops 5.2.3 Modulation of Voltage Gating5.3 Effect of pH; 5.4 Polyamine Modulation; 5.5 Others; 5.6 Concluding Remarks; Acknowledgements; References; 6 Reconstitution of General Diffusion Pores from Bacterial Outer Membranes; 6.1 Introduction; 6.2 Planar Lipid Bilayer Technique; 6.3 Intrinsic Properties of General Diffusion Channels; 6.3.1 Single-channel Analysis of OmpF Gating; 6.3.2 Molecular Origin of Voltage Gating; 6.3.3 Effect of Membrane Composition and OmpF-LPS Interactions; 6.3.4 Open-channel Conductance; 6.3.5 Voltage Effect and Channel Orientation; 6.3.6 Ion Selectivity 6.3.7 The Permeating Cations Interact with Specific Elements along the Ionic Pathway |
Record Nr. | UNINA-9910830254203321 |
Weinheim [Germany], : Wiley-VCH, c2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Bacterial and eukaryotic porins [[electronic resource] ] : structure, function, mechanism / / edited by Roland Benz |
Pubbl/distr/stampa | Weinheim [Germany], : Wiley-VCH, c2004 |
Descrizione fisica | 1 online resource (388 p.) |
Disciplina | 572.6 |
Altri autori (Persone) | BenzRoland <1943-> |
Soggetto topico |
Molecules
Proteins - Structure |
ISBN |
1-280-51962-2
9786610519620 3-527-60387-5 3-527-60422-7 |
Classificazione | 42.15 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Bacterial and Eukaryotic Porins; Contents; Preface; References; List of Contributors; 1 Regulation of Porin Gene Expression by the Two-component Regulatory System EnvZ/OmpR; 1.1 Introduction; 1.2 The Structure of EnvZ; 1.3 Biochemical Activities of EnvZ underlie Signaling; 1.4 What is the EnvZ Activity Regulated by the Stimulus?; 1.5 How is the Signal Propagated?; 1.6 Is there a Role for Acetyl-phosphate in OmpR-P Production?; 1.7 The OmpR Subfamily; 1.8 OmpR Binding Sites; 1.9 Recruitment of RNA Polymerase to OmpR-dependent Promoters; 1.10 OmpR-RNAP Interaction Surface
1.11 Affinity Model of Porin Gene Regulation1.12 A Test of the Affinity Model; 1.13 Conformational Changes in OmpR Contribute to Differential Regulation of the Porin Genes; 1.14 Other Factors that Regulate ompF and ompC; 1.15 OmpR is a Global Regulator; 1.15.1 Flagellar Biosynthesis; 1.15.2 Curli Fimbriae Production; 1.15.3 Virulence; Acknowledgments; References; 2 The Structures of General Porins; 2.1 Bacterial Outer Membrane Proteins; 2.2 Construction of General Porins; 2.3 Trimer Association and Folding; 2.4 Pore Geometry; 2.5 Permeation; 2.6 Conclusion; Acknowledgments; References 3 Role of Bacterial Porins in Antibiotic Susceptibility of Gram-negative Bacteria3.1 Introduction; 3.2 Role of Porins in Antibiotic Resistance; 3.2.1 Evolution of Clinical Isolates; 3.2.2 Expression of a Modified Porin; 3.3 In Vitro Mutagenesis Analyses of Porins and Modeling; 3.3.1 Mutations in the Loop 3 Domain; 3.3.2 Mutations in the Anti-loop 3 Domain; 3.3.3 Modeling of β-Lactam in the OmpF Eyelet; 3.4 Conclusion; Acknowledgments; References; 4 Porins of the Outer Membrane of Pseudomonas aeruginosa; 4.1 Introduction; 4.2 The Outer Membrane Permeability Defect in P. aeruginosa 4.3 Porins Identified in the Genome Sequence4.4 The General Porins; 4.4.1 OprF; 4.4.2 Other General Porins; 4.5 Efflux; 4.5.1 OprM; 4.5.2 OprM Homologs; 4.6 Specific Porins; 4.6.1 OprB; 4.6.2 OprP and OprO; 4.6.3 OprD; 4.6.4 OprD Homologs; 4.7 TonB-dependent Receptors; 4.7.1 FpvA; 4.7.2 FptA; 4.7.3 PfeA and PirA; 4.7.4 HasR, PhuR and OptI; 4.7.5 Other TonB-dependent Receptors; 4.8 Conclusions; Acknowledgments; References; 5 Regulation of Bacterial Porin Function; 5.1 Introduction; 5.2 Voltage Dependence; 5.2.1 L3 and the Constriction Zone; 5.2.2 Extracellular Loops 5.2.3 Modulation of Voltage Gating5.3 Effect of pH; 5.4 Polyamine Modulation; 5.5 Others; 5.6 Concluding Remarks; Acknowledgements; References; 6 Reconstitution of General Diffusion Pores from Bacterial Outer Membranes; 6.1 Introduction; 6.2 Planar Lipid Bilayer Technique; 6.3 Intrinsic Properties of General Diffusion Channels; 6.3.1 Single-channel Analysis of OmpF Gating; 6.3.2 Molecular Origin of Voltage Gating; 6.3.3 Effect of Membrane Composition and OmpF-LPS Interactions; 6.3.4 Open-channel Conductance; 6.3.5 Voltage Effect and Channel Orientation; 6.3.6 Ion Selectivity 6.3.7 The Permeating Cations Interact with Specific Elements along the Ionic Pathway |
Record Nr. | UNINA-9910841714103321 |
Weinheim [Germany], : Wiley-VCH, c2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Crystallography made crystal clear [[electronic resource] ] : a guide for users of macromolecular models / / Gale Rhodes |
Autore | Rhodes Gale |
Edizione | [3rd ed.] |
Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier/Academic Press, c2006 |
Descrizione fisica | 1 online resource (354 p.) |
Disciplina | 547/.7 |
Collana | Complementary science series |
Soggetto topico |
X-ray crystallography
Macromolecules - Structure Proteins - Structure |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-64149-5
9786610641499 0-08-045554-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Contents; Preface to the Third Edition; Preface to the Second Edition; Preface to the First Edition; Model and Molecule; An Overview of Protein Crystallography; Protein Crystals; Collecting Diffraction Data; From Diffraction Data to Electron Density; Obtaining Phases; Obtaining and Judging the Molecular Model; A User's Guide to Crystallographic Models; Other Diffraction Methods; Other Kinds of Macromolecular Models; Tools for Studying Macromolecules; Viewing Stereo Images; Index |
Record Nr. | UNINA-9910458096203321 |
Rhodes Gale | ||
Amsterdam ; ; Boston, : Elsevier/Academic Press, c2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Crystallography made crystal clear [[electronic resource] ] : a guide for users of macromolecular models / / Gale Rhodes |
Autore | Rhodes Gale |
Edizione | [3rd ed.] |
Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier/Academic Press, c2006 |
Descrizione fisica | 1 online resource (354 p.) |
Disciplina | 547/.7 |
Collana | Complementary science series |
Soggetto topico |
X-ray crystallography
Macromolecules - Structure Proteins - Structure |
ISBN |
1-280-64149-5
9786610641499 0-08-045554-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Contents; Preface to the Third Edition; Preface to the Second Edition; Preface to the First Edition; Model and Molecule; An Overview of Protein Crystallography; Protein Crystals; Collecting Diffraction Data; From Diffraction Data to Electron Density; Obtaining Phases; Obtaining and Judging the Molecular Model; A User's Guide to Crystallographic Models; Other Diffraction Methods; Other Kinds of Macromolecular Models; Tools for Studying Macromolecules; Viewing Stereo Images; Index |
Record Nr. | UNINA-9910784571203321 |
Rhodes Gale | ||
Amsterdam ; ; Boston, : Elsevier/Academic Press, c2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Crystallography made crystal clear [[electronic resource] ] : a guide for users of macromolecular models / / Gale Rhodes |
Autore | Rhodes Gale |
Edizione | [3rd ed.] |
Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier/Academic Press, c2006 |
Descrizione fisica | 1 online resource (354 p.) |
Disciplina | 547/.7 |
Collana | Complementary science series |
Soggetto topico |
X-ray crystallography
Macromolecules - Structure Proteins - Structure |
ISBN |
1-280-64149-5
9786610641499 0-08-045554-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Contents; Preface to the Third Edition; Preface to the Second Edition; Preface to the First Edition; Model and Molecule; An Overview of Protein Crystallography; Protein Crystals; Collecting Diffraction Data; From Diffraction Data to Electron Density; Obtaining Phases; Obtaining and Judging the Molecular Model; A User's Guide to Crystallographic Models; Other Diffraction Methods; Other Kinds of Macromolecular Models; Tools for Studying Macromolecules; Viewing Stereo Images; Index |
Record Nr. | UNINA-9910816963303321 |
Rhodes Gale | ||
Amsterdam ; ; Boston, : Elsevier/Academic Press, c2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Crystallography made crystal clear : a guide for users of macromolecular models / Gale Rhodes |
Autore | Rhodes, Gale |
Edizione | [2nd. ed.] |
Pubbl/distr/stampa | San Diego : Academic Press, c2000 |
Descrizione fisica | xix, 269 p., [16] p. of col. plates : ill. ; 23 cm |
Disciplina | 547.75046 |
Soggetto topico |
X-ray crystallography
Macromolecules - Structure Proteins - Structure |
ISBN | 0125870728 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNISALENTO-991001926979707536 |
Rhodes, Gale | ||
San Diego : Academic Press, c2000 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. del Salento | ||
|
From genome to proteome : advances in the practice and application of proteomics / / edited by Michael J. Dunn |
Pubbl/distr/stampa | Weinheim, [Germany] : , : Wiley-VCH, , 2000 |
Descrizione fisica | 1 online resource (556 p.) |
Disciplina | 572.6 |
Soggetto topico |
Proteins - Analysis
Proteins - Structure Proteomics |
Soggetto genere / forma | Electronic books. |
ISBN |
1-282-01041-7
9786612010415 3-527-61348-X 3-527-61349-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | From Genome to Proteome; Contents; Reviews; Sample preparation and solubilization; Developments in electrophoresis; Detection and quantitation; Mass spectrometry; Proteome data analysis and management; Prokaryotes and yeast; Biological Fluids; Eukaryotic cells and tissue; Oncology; Plants; Index |
Record Nr. | UNINA-9910144734103321 |
Weinheim, [Germany] : , : Wiley-VCH, , 2000 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
From genome to proteome : advances in the practice and application of proteomics / / edited by Michael J. Dunn |
Pubbl/distr/stampa | Weinheim, [Germany] : , : Wiley-VCH, , 2000 |
Descrizione fisica | 1 online resource (556 p.) |
Disciplina | 572.6 |
Soggetto topico |
Proteins - Analysis
Proteins - Structure Proteomics |
ISBN |
1-282-01041-7
9786612010415 3-527-61348-X 3-527-61349-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | From Genome to Proteome; Contents; Reviews; Sample preparation and solubilization; Developments in electrophoresis; Detection and quantitation; Mass spectrometry; Proteome data analysis and management; Prokaryotes and yeast; Biological Fluids; Eukaryotic cells and tissue; Oncology; Plants; Index |
Record Nr. | UNINA-9910829973503321 |
Weinheim, [Germany] : , : Wiley-VCH, , 2000 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Global strategies for disease detection and treatment [[electronic resource] ] : proteomics / / guest editor Sam Hanash ; foreword by Sudhir Srivastava and Sam Hanash |
Pubbl/distr/stampa | Amsterdam, : International Organisations Services, 2001 |
Descrizione fisica | 1 online resource (115 p.) |
Disciplina | 572.6 |
Altri autori (Persone) |
SrivastavaSudhir <1954->
HanashSamir M |
Collana | Disease markers |
Soggetto topico |
Proteomics
Proteins - Structure Protein binding Gene expression DNA microarrays Post-translational modification |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-50548-6
9786610505487 600-00-0441-9 1-60129-430-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Foreword: Global Strategies for Disease Detection and Treatment: Proteomics; Proteome analysis - A novel approach to understand the pathogenesis of Type 1 diabetes mellitus; Proteomic-based approach for the identification of tumor markers associated with hepatocellular carcinoma; The application of protein microarrays to serum diagnostics: Prostate cancer as a test case; Protein expression analysis: From 'tip of the iceberg' to a global method; Analysis of the proteomic profiling of brain tissue in Alzheimer's disease; Proteomics and the inner ear
Proteomics as the tool to search for lung disease markers in bronchoalveolar lavagePseudomonas aeruginosa and a proteomic approach to bacterial pathogenesis; A proteomic approach to the identification of lung cancer markers; Proteomic patterns of nipple aspirate fluids obtained by SELDI-TOF: Potential for new biomarkers to aid in the diagnosis of breast cancer; Author Index Volume 17 (2001); Keyword Index Volume 17 (2001) |
Record Nr. | UNINA-9910455941703321 |
Amsterdam, : International Organisations Services, 2001 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|