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Biophysics for therapeutic protein development / / Linda O. Narhi, editor
| Biophysics for therapeutic protein development / / Linda O. Narhi, editor |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, : Springer, 2013 |
| Descrizione fisica | 1 online resource (297 p.) |
| Disciplina | 615.58 |
| Altri autori (Persone) | NarhiLinda O |
| Collana | Biophysics for the life sciences |
| Soggetto topico |
Proteins - Biotechnology
Cell culture Proteins - Synthesis Proteins - Therapeutic use Biophysics |
| ISBN |
1-299-40831-1
1-4614-4316-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- High Throughput Biophysical Approaches to Therapeutic Protein Development -- Techniques for Higher Order Structure Determination -- Biophysical Techniques for Protein Size Distribution Analysis -- Qualification of biophysical methods for the analysis of protein therapeutics -- Application of Biophysics to the Early Developability Assessment of Therapeutic Candidates and its Application to Enhance Developability Properties -- Application of Biophysics in Formulation, Process and Product Characterization: Selected Case Studies -- Biophysical Analysis in Support of Development of Protein Pharmaceuticals -- Case Studies Applying Biophysical Techniques to Better Characterize Protein Aggregates and Particulates of Varying Size -- Investigation of Non Conformance During Protein Therapeutic Manufacturing -- Higher order structure and protein aggregate characterization of protein therapeutics: perspectives from good manufacturing practices and regulatory guidance -- Index. |
| Record Nr. | UNINA-9910437842603321 |
| New York, : Springer, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Co- and post-translational modifications of therapeutic antibodies and proteins / / T. Shantha Raju
| Co- and post-translational modifications of therapeutic antibodies and proteins / / T. Shantha Raju |
| Autore | Raju T. Shantha |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley, , [2019] |
| Descrizione fisica | 1 online resource (315 pages) |
| Disciplina | 660.63 |
| Soggetto topico | Proteins - Biotechnology |
| ISBN |
1-119-05334-X
1-119-05335-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910555060103321 |
Raju T. Shantha
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| Hoboken, New Jersey : , : Wiley, , [2019] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Co- and post-translational modifications of therapeutic antibodies and proteins / / T. Shantha Raju
| Co- and post-translational modifications of therapeutic antibodies and proteins / / T. Shantha Raju |
| Autore | Raju T. Shantha |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley, , [2019] |
| Descrizione fisica | 1 online resource (315 pages) |
| Disciplina | 660.63 |
| Soggetto topico | Proteins - Biotechnology |
| ISBN |
1-119-05334-X
1-119-05335-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction to co- and post-translational modifications of proteins -- Acetylation of proteins -- C-terminal Lys or Arg clipping in proteins -- Cysteinylation of proteins -- Deamidation of proteins -- Glycation of proteins -- Glycosylation of proteins -- N-glycosylation of proteins -- O-glycosylation of proteins -- Hydroxylation of proteins -- Methylation of proteins -- Oxidation of proteins -- Phosphorylation of proteins -- Prenylation of proteins -- Proteolysis of proteins -- Selenylation -- Signal peptides -- Sulfation of proteins and glycoproteins -- Sumoylation -- Ubiquitination -- Other CTMs and PTMs of proteins. |
| Record Nr. | UNINA-9910830815503321 |
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Raju T. Shantha
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| Hoboken, New Jersey : , : Wiley, , [2019] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Expert review of proteomics
| Expert review of proteomics |
| Pubbl/distr/stampa | London : , : Future Drugs Ltd. |
| Disciplina | 572.6 |
| Soggetto topico |
Proteins - Biotechnology
Proteomics |
| Soggetto genere / forma | Periodicals. |
| ISSN | 1744-8387 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Proteomics
Expert rev. proteomics |
| Record Nr. | UNISA-996335910603316 |
| London : , : Future Drugs Ltd. | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Expert review of proteomics
| Expert review of proteomics |
| Pubbl/distr/stampa | London : , : Future Drugs Ltd. |
| Disciplina | 572.6 |
| Soggetto topico |
Proteins - Biotechnology
Proteomics Protéines - Biotechnologie Protéomique |
| Soggetto genere / forma | Periodicals. |
| ISSN | 1744-8387 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Proteomics
Expert rev. proteomics |
| Record Nr. | UNINA-9910143534903321 |
| London : , : Future Drugs Ltd. | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ionic liquids in biotransformations and organocatalysis [[electronic resource] ] : solvents and beyond / / edited by Pablo Domínguez de María
| Ionic liquids in biotransformations and organocatalysis [[electronic resource] ] : solvents and beyond / / edited by Pablo Domínguez de María |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2012 |
| Descrizione fisica | 1 online resource (455 p.) |
| Disciplina | 572.6 |
| Altri autori (Persone) | Domínguez de MaríaPablo <1974-> |
| Soggetto topico |
Proteins - Biotechnology
Ionic solutions Catalysis |
| ISBN |
1-299-31449-X
1-118-15874-1 1-118-15875-X 1-118-15872-5 |
| Classificazione | SCI010000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | pt. I. Fundamentals -- pt. II. Ionic liquids in biotransformations -- pt. III. Ionic liquids in organocatalysis. |
| Record Nr. | UNINA-9910141296903321 |
| Hoboken, N.J., : Wiley, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ionic liquids in biotransformations and organocatalysis : solvents and beyond / / edited by Pablo Domínguez de María
| Ionic liquids in biotransformations and organocatalysis : solvents and beyond / / edited by Pablo Domínguez de María |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2012 |
| Descrizione fisica | 1 online resource (455 p.) |
| Disciplina | 572.6 |
| Altri autori (Persone) | Domínguez de MaríaPablo <1974-> |
| Soggetto topico |
Proteins - Biotechnology
Ionic solutions Catalysis |
| ISBN |
1-299-31449-X
1-118-15874-1 1-118-15875-X 1-118-15872-5 |
| Classificazione | SCI010000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | pt. I. Fundamentals -- pt. II. Ionic liquids in biotransformations -- pt. III. Ionic liquids in organocatalysis. |
| Record Nr. | UNINA-9910825351903321 |
| Hoboken, N.J., : Wiley, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mammalian cell biotechnology in protein production [[electronic resource] /] / editors, Hansjörg Hauser, Roland Wagner
| Mammalian cell biotechnology in protein production [[electronic resource] /] / editors, Hansjörg Hauser, Roland Wagner |
| Pubbl/distr/stampa | Berlin ; ; New York, : Walter de Gruyter, 1997 |
| Descrizione fisica | 1 online resource (512 p.) |
| Disciplina | 660/.63 |
| Altri autori (Persone) |
HauserHansjörg <1949->
WagnerRoland <1956-> |
| Soggetto topico |
Proteins - Biotechnology
Animal cell biotechnology Mammals - Cytology |
| Soggetto genere / forma | Electronic books. |
| ISBN | 3-11-080928-1 |
| Classificazione | WF 9720 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Frontmatter -- Preface -- Contents -- Contributors List -- 1. Genetic Manipulation of Mammalian Cells -- 1.1 Heterologous Expression of Genes in Mammalian Cells / Hauser, Hansjörg -- 1.2 Permanent Gene Expression in Mammalian Cells: Gene Transfer And Selection / Schlokat, Uwe / Himmelspach, Michèle / Falkner, Falko G. / Dorner, Friedrich -- 1.3 Vectors for Gene Transfer and Expression in Animal Cells / Sandig, Volker / Lieber, Andre / Strauss, Michael -- 1.4 Aspects of Gene Transfer and Gene Amplification in Recombinant Mammalian Cells / Wurm, Florian Μ. -- 1.5 Isolation of Recombinant Cell Clones Exhibiting High-Level Expression of the Introduced Gene / Wirth, Manfred -- 1.6 Genetic Engineering of Antibodies and Derivatives from Mammalian Cells / Schäffner, Michaela / Kaluza, Brigitte / Weidle, Ulrich Η. -- 1.7 Safety Evaluation of Products Derived From Mammalian Cell Lines / Onions, David -- 2. Biological Aspects of Animal Cells -- 2.1 Metabolic Control of Animal Cell Culture Processes / Wagner, Roland -- 2.2 Glycosylation: A Post-Translational Modification / Savage, Angela -- 3. Cell Cultivation Technology -- 3.1 Bioreactors Designed for Animal Cells / Tokashiki, Michiyuki / Yokoyama, Seiichi -- 3.2 Hydrodynamic Properties in Bioreactors / Chattopadhyay, Devamita / Garcia-Briones, Miguel / Venkat, Raghavan / Chalmers, Jeffrey J. -- 3.3 Kinetics and Simulation of Animal Cell Processes / Goergen, Jean-Louis / Marc, Annie / Engasser, Jean-Marc -- 3.4 On-line and Off-line Process Analysis / Scheper, Thomas / Freitag, Ruth / Scrienc, Friedrich -- 4. Down-Stream Processing -- 4.1 Principles of Product Extraction from Cell Culture and Purification for Pharmaceutical Proteins / Jungbauer, Alois -- 4.2 Validation of Downstream Processes / Walter, Joachim / Allgaier, Hermann -- Index -- Backmatter |
| Record Nr. | UNINA-9910453537603321 |
| Berlin ; ; New York, : Walter de Gruyter, 1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Mammalian cell biotechnology in protein production [[electronic resource] /] / editors, Hansjörg Hauser, Roland Wagner
| Mammalian cell biotechnology in protein production [[electronic resource] /] / editors, Hansjörg Hauser, Roland Wagner |
| Pubbl/distr/stampa | Berlin ; ; New York, : Walter de Gruyter, 1997 |
| Descrizione fisica | 1 online resource (512 p.) |
| Disciplina | 660/.63 |
| Altri autori (Persone) |
HauserHansjörg <1949->
WagnerRoland <1956-> |
| Soggetto topico |
Proteins - Biotechnology
Animal cell biotechnology Mammals - Cytology |
| ISBN | 3-11-080928-1 |
| Classificazione | WF 9720 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Frontmatter -- Preface -- Contents -- Contributors List -- 1. Genetic Manipulation of Mammalian Cells -- 1.1 Heterologous Expression of Genes in Mammalian Cells / Hauser, Hansjörg -- 1.2 Permanent Gene Expression in Mammalian Cells: Gene Transfer And Selection / Schlokat, Uwe / Himmelspach, Michèle / Falkner, Falko G. / Dorner, Friedrich -- 1.3 Vectors for Gene Transfer and Expression in Animal Cells / Sandig, Volker / Lieber, Andre / Strauss, Michael -- 1.4 Aspects of Gene Transfer and Gene Amplification in Recombinant Mammalian Cells / Wurm, Florian Μ. -- 1.5 Isolation of Recombinant Cell Clones Exhibiting High-Level Expression of the Introduced Gene / Wirth, Manfred -- 1.6 Genetic Engineering of Antibodies and Derivatives from Mammalian Cells / Schäffner, Michaela / Kaluza, Brigitte / Weidle, Ulrich Η. -- 1.7 Safety Evaluation of Products Derived From Mammalian Cell Lines / Onions, David -- 2. Biological Aspects of Animal Cells -- 2.1 Metabolic Control of Animal Cell Culture Processes / Wagner, Roland -- 2.2 Glycosylation: A Post-Translational Modification / Savage, Angela -- 3. Cell Cultivation Technology -- 3.1 Bioreactors Designed for Animal Cells / Tokashiki, Michiyuki / Yokoyama, Seiichi -- 3.2 Hydrodynamic Properties in Bioreactors / Chattopadhyay, Devamita / Garcia-Briones, Miguel / Venkat, Raghavan / Chalmers, Jeffrey J. -- 3.3 Kinetics and Simulation of Animal Cell Processes / Goergen, Jean-Louis / Marc, Annie / Engasser, Jean-Marc -- 3.4 On-line and Off-line Process Analysis / Scheper, Thomas / Freitag, Ruth / Scrienc, Friedrich -- 4. Down-Stream Processing -- 4.1 Principles of Product Extraction from Cell Culture and Purification for Pharmaceutical Proteins / Jungbauer, Alois -- 4.2 Validation of Downstream Processes / Walter, Joachim / Allgaier, Hermann -- Index -- Backmatter |
| Record Nr. | UNINA-9910790718603321 |
| Berlin ; ; New York, : Walter de Gruyter, 1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Mammalian cell biotechnology in protein production / / editors, Hansjörg Hauser, Roland Wagner
| Mammalian cell biotechnology in protein production / / editors, Hansjörg Hauser, Roland Wagner |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Berlin ; ; New York, : Walter de Gruyter, 1997 |
| Descrizione fisica | 1 online resource (512 p.) |
| Disciplina |
660/.63
660.63 |
| Altri autori (Persone) |
HauserHansjörg <1949->
WagnerRoland <1956-> |
| Soggetto topico |
Proteins - Biotechnology
Animal cell biotechnology Mammals - Cytology |
| ISBN | 3-11-080928-1 |
| Classificazione | WF 9720 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Frontmatter -- Preface -- Contents -- Contributors List -- 1. Genetic Manipulation of Mammalian Cells -- 1.1 Heterologous Expression of Genes in Mammalian Cells / Hauser, Hansjörg -- 1.2 Permanent Gene Expression in Mammalian Cells: Gene Transfer And Selection / Schlokat, Uwe / Himmelspach, Michèle / Falkner, Falko G. / Dorner, Friedrich -- 1.3 Vectors for Gene Transfer and Expression in Animal Cells / Sandig, Volker / Lieber, Andre / Strauss, Michael -- 1.4 Aspects of Gene Transfer and Gene Amplification in Recombinant Mammalian Cells / Wurm, Florian Μ. -- 1.5 Isolation of Recombinant Cell Clones Exhibiting High-Level Expression of the Introduced Gene / Wirth, Manfred -- 1.6 Genetic Engineering of Antibodies and Derivatives from Mammalian Cells / Schäffner, Michaela / Kaluza, Brigitte / Weidle, Ulrich Η. -- 1.7 Safety Evaluation of Products Derived From Mammalian Cell Lines / Onions, David -- 2. Biological Aspects of Animal Cells -- 2.1 Metabolic Control of Animal Cell Culture Processes / Wagner, Roland -- 2.2 Glycosylation: A Post-Translational Modification / Savage, Angela -- 3. Cell Cultivation Technology -- 3.1 Bioreactors Designed for Animal Cells / Tokashiki, Michiyuki / Yokoyama, Seiichi -- 3.2 Hydrodynamic Properties in Bioreactors / Chattopadhyay, Devamita / Garcia-Briones, Miguel / Venkat, Raghavan / Chalmers, Jeffrey J. -- 3.3 Kinetics and Simulation of Animal Cell Processes / Goergen, Jean-Louis / Marc, Annie / Engasser, Jean-Marc -- 3.4 On-line and Off-line Process Analysis / Scheper, Thomas / Freitag, Ruth / Scrienc, Friedrich -- 4. Down-Stream Processing -- 4.1 Principles of Product Extraction from Cell Culture and Purification for Pharmaceutical Proteins / Jungbauer, Alois -- 4.2 Validation of Downstream Processes / Walter, Joachim / Allgaier, Hermann -- Index -- Backmatter |
| Record Nr. | UNINA-9910827447303321 |
| Berlin ; ; New York, : Walter de Gruyter, 1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
