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Androgen-responsive genes in prostate cancer : regulation, function and clinical applications / / edited by Zhou Wang
Androgen-responsive genes in prostate cancer : regulation, function and clinical applications / / edited by Zhou Wang
Edizione [1st ed. 2013.]
Pubbl/distr/stampa New York, : Springer, 2013
Descrizione fisica 1 online resource (346 p.)
Disciplina 616.994630695
Altri autori (Persone) WangZhou
Soggetto topico Prostate - Cancer - Genetic aspects
Prostate - Cancer - Treatment
ISBN 1-299-33798-8
1-4614-6182-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Roles of androgen receptor coregulators and cell signaling in regulation of androgen-responsive genes -- Selective and classical Androgen Response Elements in androgen-regulated gene expression -- Negative androgen-response elements in androgen target genes -- Chromatin looping and long distance regulation by androgen receptor -- The Functionality of Prostate Cancer Predisposition Risk Regions is revealed by AR Enhancers -- Mechanisms of ARE-independent Gene Activation by the Androgen Receptor in Prostate Cancer Cells: potential targets for better intervention strategies -- Androgen action, Wnt signaling, and prostate tumorigenesis -- Toward Revealing the Complexity of Androgen Responsive Protein and Non-coding Transcripts in Prostate Cancer -- Androgen-Responsive Gene Expression in Prostate Cancer Progression -- Androgen receptor regulated genes in prostate cancer initiation vs metastasis -- Androgen-Independent Induction of Androgen-Responsive Genes By Interleukin-6 Regulation -- The effect of AR overexpression on androgen signaling in prostate cancer -- The expression signature of androgen receptor splice variants and their distinctive transcriptional activities in castration-resistant prostate cancer -- Androgen regulation of the cell cycle in prostate cancer -- Androgen Receptor Signaling Interactions Control Epithelial-Mesenchymal Transition (EMT) in Prostate Cancer Progression -- Androgen receptor regulation of serum response factor signaling in prostate cancer -- Regulation of angiogenesis by androgen-responsive gene EAF2 -- The role of miR-21, an androgen-regulated microRNA, in prostate cancer -- Androgen dependent oncogenic activation of ETS transcription factors by recurrent gene fusions in prostate cancer: Biological and Clinical Implications -- Clusterin as a target for treatment of castration-resistant prostate cancer -- Index.
Record Nr. UNINA-9910739436903321
New York, : Springer, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Stem cells and prostate cancer / / Scott D. Cramer, editor
Stem cells and prostate cancer / / Scott D. Cramer, editor
Edizione [1st ed. 2013.]
Pubbl/distr/stampa New York, : Springer, c2013
Descrizione fisica 1 online resource (182 p.)
Disciplina 616.99
616.99/463
Altri autori (Persone) CramerScott D
Soggetto topico Prostate - Cancer - Genetic aspects
Stem cells
ISBN 1-4614-6498-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Stem Cells and Prostate Development -- Isolation and Characterization of Prostate Stem Cells -- Prostate tumor initiating cells -- TIC Markers and methods of characterization -- Genetic Control of Self Renewal of the TIC -- Therapeutic targeting of the prostate TIC.- The prostate stem cell niche.- Tumor stroma control of the prostate TIC.- Targeting the prostate stem cell for chemoprevention.- Stem cell models for functional validation of prostate cancer genes -- Index .
Record Nr. UNINA-9910739427003321
New York, : Springer, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui