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Prodrugs and drug delivery / / Jarkko Rautio
| Prodrugs and drug delivery / / Jarkko Rautio |
| Autore | Rautio Jarkko (University of Eastern Finland, Finland) |
| Pubbl/distr/stampa | London, : Henry Stewart Talks, 2013 |
| Descrizione fisica | 1 online resource (1 streaming video file (38 min.) : color, sound) |
| Collana | Small molecule drug discovery |
| Soggetto topico |
Drug delivery systems
Molecular pharmacology Prodrugs - Design Prodrugs Drug Delivery Systems Drug Design Drug Discovery Prodrugs - pharmacokinetics |
| Formato | Videoregistrazioni  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Contents: Prodrugs and drug delivery -- Prodrug concept and designing prodrugs -- Solving ADMET properties -- Prevalence, recent approvals and best-sellers. |
| Record Nr. | UNINA-9910888009603321 |
Rautio Jarkko (University of Eastern Finland, Finland)
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| London, : Henry Stewart Talks, 2013 | ||
| Videoregistrazioni | ||
| Lo trovi qui: Univ. Federico II | ||
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Prodrugs and targeted delivery [[electronic resource] ] : towards better ADME properties / / edited by Jarkko Rautio
| Prodrugs and targeted delivery [[electronic resource] ] : towards better ADME properties / / edited by Jarkko Rautio |
| Pubbl/distr/stampa | Weinheim, Germany, : Wiley-VCH, 2011 |
| Descrizione fisica | 1 online resource (522 p.) |
| Disciplina |
615.19
615.191 |
| Altri autori (Persone) | RautioJarkko |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico | Prodrugs |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-283-14057-8
9786613140579 3-527-63318-9 3-527-63316-2 3-527-63317-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Prodrugs and Targeted Delivery: Towards Better ADME Properties; Contents; List of Contributors; Preface; A Personal Foreword; Part One: Prodrug Design and Intellectual Property; 1 Prodrug Strategies in Drug Design; 2 The Molecular Design of Prodrugs by Functional Group; 3 Intellectual Property Primer on Pharmaceutical Patents with a Special Emphasis on Prodrugs and Metabolites; Part Two: Prodrugs Addressing ADMET Issues; 4 Increasing Lipophilicity for Oral Drug Delivery; 5 Modulating Solubility Through Prodrugs for Oral and IV Drug Delivery
6 Prodrugs Designed to Target Transporters for Oral Drug Delivery7 Topical and Transdermal Delivery Using Prodrugs: Mechanism of Enhancement; 8 Ocular Delivery Using Prodrugs; 9 Reducing Presystemic Drug Metabolism; 10 Enzyme-Activated Prodrug Strategies for Site-Selective Drug Delivery; 11 Prodrug Approaches for Central Nervous System Delivery; 12 Directed Enzyme Prodrug Therapies; Part Three: Codrugs and Soft Drugs; 13 Improving the Use of Drug Combinations Through the Codrug Approach; 14 Soft Drugs; Part Four: Preclinical and Clinical Consideration for Prodrugs 15 Pharmacokinetic and Biopharmaceutical Considerations in Prodrug Discovery and Development16 The Impact of Pharmacogenetics on the Clinical Outcomes of Prodrugs; Index |
| Record Nr. | UNINA-9910140873003321 |
| Weinheim, Germany, : Wiley-VCH, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Prodrugs and targeted delivery : towards better ADME properties / / edited by Jarkko Rautio
| Prodrugs and targeted delivery : towards better ADME properties / / edited by Jarkko Rautio |
| Pubbl/distr/stampa | Weinheim, Germany, : Wiley-VCH, 2011 |
| Descrizione fisica | 1 online resource (522 p.) |
| Disciplina |
615.19
615.191 |
| Altri autori (Persone) | RautioJarkko |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico | Prodrugs |
| ISBN |
9786613140579
9781283140577 1283140578 9783527633180 3527633189 9783527633166 3527633162 9783527633173 3527633170 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Prodrugs and Targeted Delivery: Towards Better ADME Properties; Contents; List of Contributors; Preface; A Personal Foreword; Part One: Prodrug Design and Intellectual Property; 1 Prodrug Strategies in Drug Design; 2 The Molecular Design of Prodrugs by Functional Group; 3 Intellectual Property Primer on Pharmaceutical Patents with a Special Emphasis on Prodrugs and Metabolites; Part Two: Prodrugs Addressing ADMET Issues; 4 Increasing Lipophilicity for Oral Drug Delivery; 5 Modulating Solubility Through Prodrugs for Oral and IV Drug Delivery
6 Prodrugs Designed to Target Transporters for Oral Drug Delivery7 Topical and Transdermal Delivery Using Prodrugs: Mechanism of Enhancement; 8 Ocular Delivery Using Prodrugs; 9 Reducing Presystemic Drug Metabolism; 10 Enzyme-Activated Prodrug Strategies for Site-Selective Drug Delivery; 11 Prodrug Approaches for Central Nervous System Delivery; 12 Directed Enzyme Prodrug Therapies; Part Three: Codrugs and Soft Drugs; 13 Improving the Use of Drug Combinations Through the Codrug Approach; 14 Soft Drugs; Part Four: Preclinical and Clinical Consideration for Prodrugs 15 Pharmacokinetic and Biopharmaceutical Considerations in Prodrug Discovery and Development16 The Impact of Pharmacogenetics on the Clinical Outcomes of Prodrugs; Index |
| Record Nr. | UNINA-9911020108703321 |
| Weinheim, Germany, : Wiley-VCH, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Synthese von photo-aktivierbaren Prodrugs von Duocarmycin-Analoga / / Michael Müller
| Synthese von photo-aktivierbaren Prodrugs von Duocarmycin-Analoga / / Michael Müller |
| Autore | Müller Michael |
| Pubbl/distr/stampa | Göttingen, [Germany] : , : Cuvillier Verlag, , 2011 |
| Descrizione fisica | 1 online resource (303 pages) : illustrations |
| Disciplina | 615.19 |
| Soggetto topico | Prodrugs |
| ISBN | 3-7369-3952-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Record Nr. | UNINA-9910794978503321 |
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Müller Michael
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| Göttingen, [Germany] : , : Cuvillier Verlag, , 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Synthese von photo-aktivierbaren Prodrugs von Duocarmycin-Analoga / / Michael Müller
| Synthese von photo-aktivierbaren Prodrugs von Duocarmycin-Analoga / / Michael Müller |
| Autore | Müller Michael |
| Pubbl/distr/stampa | Göttingen, [Germany] : , : Cuvillier Verlag, , 2011 |
| Descrizione fisica | 1 online resource (303 pages) : illustrations |
| Disciplina | 615.19 |
| Soggetto topico | Prodrugs |
| ISBN | 3-7369-3952-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Record Nr. | UNINA-9910810566603321 |
|
Müller Michael
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||
| Göttingen, [Germany] : , : Cuvillier Verlag, , 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Prodrugs
(5)
- Drug Delivery Systems (1)
- Drug Design (1)
- Drug Discovery (1)
- Drug delivery systems (1)