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Biology of the prokaryotes [[electronic resource] /] / edited by Joseph W. Lengeler, Gerhart Drews, Hans G. Schlegel
| Biology of the prokaryotes [[electronic resource] /] / edited by Joseph W. Lengeler, Gerhart Drews, Hans G. Schlegel |
| Pubbl/distr/stampa | Stuttgart ; ; New York, : Thieme |
| Descrizione fisica | 1 online resource (986 p.) |
| Disciplina | 579.3 |
| Altri autori (Persone) |
LengelerJoseph W
DrewsG (Gerhart) SchlegelHans Günter <1924-> |
| Soggetto topico |
Prokaryotes
Microorganisms Procariotes Bacteris |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
1-282-68308-X
9786612683084 1-61344-556-3 1-4443-1331-2 1-4443-1330-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biology of the Prokaryotes; Contents; 1: Bacteriology Paved the Way to Cell Biology: a Historical Account; 1.1 New Concepts and Experimental Approaches Paved the Way for Progress; 1.2 Observations and Speculation Lead to the First Concept of the Existence of Living Infectious Agents; 1.3 Bacteria are Members of a New, Large Group of Independent Organisms; 1.4 The Introduction of Solid, Defined Media and Pure-Culture Methods Marks a True Revolution; 1.5 The New Bacteriological Methods Proved that the Causative Agents of Infectious Diseases are Bacteria
1.6 Studies on Fermentation Founded Bacterial Physiology and Biochemistry1.7 Lithoautotrophy Is the Ability of Bacteria to Obtain Energy from the Oxidation of Inorganic Compounds and Carbon from Carbon Dioxide; 1.8 Light-Dependent Processes such as Phototaxis, Light-Induced Energy Transduction, and Photoassimilation of Carbon Dioxide Took a long Time to be Understood; 1.9 Dinitrogen Fixation Is Unique to the Prokaryotes; 1.10 The Analysis of Anabolic and Catabolic Metabolism Lead to the Discovery of Substrates, Products, Apoenzymes, and Coenzymes, and, in the end, of Metabolic Pathways 1.11 Studies on Inclusion Bodies and the Structures and Functions of Cell Envelopes Revealed the Organization of the Bacterial Cell1.12 Bacterial Adaptation was Well Recognized Before the Genetic Approach Revealed the Basis of Molecular Mechanisms of Regulation; 1.13 Studies on the Metabolic Types of Bacteria Revealed Their Functions in the Biosphere; 1.14 The Goals and Methods of the Classification of Bacteria Have Changed; 1.15 Bacterial Viruses (Bacteriophages) Were Detected as Lytic Principles 1.16 Studies on Heredity in Bacteria Provided the Decisive Principles and Concepts for the Promotion of Modern Biology Including Gene Technology1.17 Epilogue; Section I: The Prokaryotic Cell; 2: Cellular and Subcellular Organization of Prokaryotes; 2.1 Prokaryotes, Though Small, Contain all Structural Elements Necessary for Survival and Multiplication; 2.2 Cellular Structures Can Be Made Visible or Identified by Numerous Methods; 2.3 Prokaryotes May Occur as Single Cells or as Cell Associations 2.4 The Structural Components of Prokaryotic Cell Envelopes Are Organized as Barriers and Interfaces2.5 The Setup of the Intracellular Structures Reflects the High Degree of Organization in the Prokaryotic Cell; 2.6 Cell Appendages Serve for Locomotion and Cell Recognition; 2.7 Bacteria May Form Spores and Other Resting Cells; Section II: Basic Prerequisites for Cellular Life; 3: Substrate-Level Phosphorylation; 3.1 ATP Synthesis Is Coupled to Exergonic Reactions; 3.2 The ATP Yield Is a Function of the Free Energy of the Driving Reaction 3.3 Coupling of ATP Synthesis to Glucose Degradation Requires C-C Cleavage and Subsequent Oxidation |
| Record Nr. | UNINA-9910139784403321 |
| Stuttgart ; ; New York, : Thieme | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biology of the prokaryotes [[electronic resource] /] / edited by Joseph W. Lengeler, Gerhart Drews, Hans G. Schlegel
| Biology of the prokaryotes [[electronic resource] /] / edited by Joseph W. Lengeler, Gerhart Drews, Hans G. Schlegel |
| Pubbl/distr/stampa | Stuttgart ; ; New York, : Thieme |
| Descrizione fisica | 1 online resource (986 p.) |
| Disciplina | 579.3 |
| Altri autori (Persone) |
LengelerJoseph W
DrewsG (Gerhart) SchlegelHans Günter <1924-> |
| Soggetto topico |
Prokaryotes
Microorganisms Procariotes Bacteris |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
1-282-68308-X
9786612683084 1-61344-556-3 1-4443-1331-2 1-4443-1330-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biology of the Prokaryotes; Contents; 1: Bacteriology Paved the Way to Cell Biology: a Historical Account; 1.1 New Concepts and Experimental Approaches Paved the Way for Progress; 1.2 Observations and Speculation Lead to the First Concept of the Existence of Living Infectious Agents; 1.3 Bacteria are Members of a New, Large Group of Independent Organisms; 1.4 The Introduction of Solid, Defined Media and Pure-Culture Methods Marks a True Revolution; 1.5 The New Bacteriological Methods Proved that the Causative Agents of Infectious Diseases are Bacteria
1.6 Studies on Fermentation Founded Bacterial Physiology and Biochemistry1.7 Lithoautotrophy Is the Ability of Bacteria to Obtain Energy from the Oxidation of Inorganic Compounds and Carbon from Carbon Dioxide; 1.8 Light-Dependent Processes such as Phototaxis, Light-Induced Energy Transduction, and Photoassimilation of Carbon Dioxide Took a long Time to be Understood; 1.9 Dinitrogen Fixation Is Unique to the Prokaryotes; 1.10 The Analysis of Anabolic and Catabolic Metabolism Lead to the Discovery of Substrates, Products, Apoenzymes, and Coenzymes, and, in the end, of Metabolic Pathways 1.11 Studies on Inclusion Bodies and the Structures and Functions of Cell Envelopes Revealed the Organization of the Bacterial Cell1.12 Bacterial Adaptation was Well Recognized Before the Genetic Approach Revealed the Basis of Molecular Mechanisms of Regulation; 1.13 Studies on the Metabolic Types of Bacteria Revealed Their Functions in the Biosphere; 1.14 The Goals and Methods of the Classification of Bacteria Have Changed; 1.15 Bacterial Viruses (Bacteriophages) Were Detected as Lytic Principles 1.16 Studies on Heredity in Bacteria Provided the Decisive Principles and Concepts for the Promotion of Modern Biology Including Gene Technology1.17 Epilogue; Section I: The Prokaryotic Cell; 2: Cellular and Subcellular Organization of Prokaryotes; 2.1 Prokaryotes, Though Small, Contain all Structural Elements Necessary for Survival and Multiplication; 2.2 Cellular Structures Can Be Made Visible or Identified by Numerous Methods; 2.3 Prokaryotes May Occur as Single Cells or as Cell Associations 2.4 The Structural Components of Prokaryotic Cell Envelopes Are Organized as Barriers and Interfaces2.5 The Setup of the Intracellular Structures Reflects the High Degree of Organization in the Prokaryotic Cell; 2.6 Cell Appendages Serve for Locomotion and Cell Recognition; 2.7 Bacteria May Form Spores and Other Resting Cells; Section II: Basic Prerequisites for Cellular Life; 3: Substrate-Level Phosphorylation; 3.1 ATP Synthesis Is Coupled to Exergonic Reactions; 3.2 The ATP Yield Is a Function of the Free Energy of the Driving Reaction 3.3 Coupling of ATP Synthesis to Glucose Degradation Requires C-C Cleavage and Subsequent Oxidation |
| Record Nr. | UNISA-996200240203316 |
| Stuttgart ; ; New York, : Thieme | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Biology of the prokaryotes [[electronic resource] /] / edited by Joseph W. Lengeler, Gerhart Drews, Hans G. Schlegel
| Biology of the prokaryotes [[electronic resource] /] / edited by Joseph W. Lengeler, Gerhart Drews, Hans G. Schlegel |
| Pubbl/distr/stampa | Stuttgart ; ; New York, : Thieme |
| Descrizione fisica | 1 online resource (986 p.) |
| Disciplina | 579.3 |
| Altri autori (Persone) |
LengelerJoseph W
DrewsG (Gerhart) SchlegelHans Günter <1924-> |
| Soggetto topico |
Prokaryotes
Microorganisms Procariotes Bacteris |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
1-282-68308-X
9786612683084 1-61344-556-3 1-4443-1331-2 1-4443-1330-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biology of the Prokaryotes; Contents; 1: Bacteriology Paved the Way to Cell Biology: a Historical Account; 1.1 New Concepts and Experimental Approaches Paved the Way for Progress; 1.2 Observations and Speculation Lead to the First Concept of the Existence of Living Infectious Agents; 1.3 Bacteria are Members of a New, Large Group of Independent Organisms; 1.4 The Introduction of Solid, Defined Media and Pure-Culture Methods Marks a True Revolution; 1.5 The New Bacteriological Methods Proved that the Causative Agents of Infectious Diseases are Bacteria
1.6 Studies on Fermentation Founded Bacterial Physiology and Biochemistry1.7 Lithoautotrophy Is the Ability of Bacteria to Obtain Energy from the Oxidation of Inorganic Compounds and Carbon from Carbon Dioxide; 1.8 Light-Dependent Processes such as Phototaxis, Light-Induced Energy Transduction, and Photoassimilation of Carbon Dioxide Took a long Time to be Understood; 1.9 Dinitrogen Fixation Is Unique to the Prokaryotes; 1.10 The Analysis of Anabolic and Catabolic Metabolism Lead to the Discovery of Substrates, Products, Apoenzymes, and Coenzymes, and, in the end, of Metabolic Pathways 1.11 Studies on Inclusion Bodies and the Structures and Functions of Cell Envelopes Revealed the Organization of the Bacterial Cell1.12 Bacterial Adaptation was Well Recognized Before the Genetic Approach Revealed the Basis of Molecular Mechanisms of Regulation; 1.13 Studies on the Metabolic Types of Bacteria Revealed Their Functions in the Biosphere; 1.14 The Goals and Methods of the Classification of Bacteria Have Changed; 1.15 Bacterial Viruses (Bacteriophages) Were Detected as Lytic Principles 1.16 Studies on Heredity in Bacteria Provided the Decisive Principles and Concepts for the Promotion of Modern Biology Including Gene Technology1.17 Epilogue; Section I: The Prokaryotic Cell; 2: Cellular and Subcellular Organization of Prokaryotes; 2.1 Prokaryotes, Though Small, Contain all Structural Elements Necessary for Survival and Multiplication; 2.2 Cellular Structures Can Be Made Visible or Identified by Numerous Methods; 2.3 Prokaryotes May Occur as Single Cells or as Cell Associations 2.4 The Structural Components of Prokaryotic Cell Envelopes Are Organized as Barriers and Interfaces2.5 The Setup of the Intracellular Structures Reflects the High Degree of Organization in the Prokaryotic Cell; 2.6 Cell Appendages Serve for Locomotion and Cell Recognition; 2.7 Bacteria May Form Spores and Other Resting Cells; Section II: Basic Prerequisites for Cellular Life; 3: Substrate-Level Phosphorylation; 3.1 ATP Synthesis Is Coupled to Exergonic Reactions; 3.2 The ATP Yield Is a Function of the Free Energy of the Driving Reaction 3.3 Coupling of ATP Synthesis to Glucose Degradation Requires C-C Cleavage and Subsequent Oxidation |
| Record Nr. | UNINA-9910829944803321 |
| Stuttgart ; ; New York, : Thieme | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Circadian rhythms in bacteria and microbiomes / / Carl Hirschie Johnson and Michael Joseph Rust (editors)
| Circadian rhythms in bacteria and microbiomes / / Carl Hirschie Johnson and Michael Joseph Rust (editors) |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (424 pages) |
| Disciplina | 579.3 |
| Soggetto topico |
Prokaryotes
Circadian rhythms Procariotes Ritmes circadiaris |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-72158-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Dedications -- Dedication to Dr. Carol Rae Andersson (May 5, 1965-January 24, 2009) She left us too soon! -- Dedication to Dr. Yohko Kitayama (1976-2016) -- To Takao Kondo on the Occasion of His Retirement -- Acknowledgments -- References -- Preface -- Contents -- The Bacterial Perspective on Circadian Clocks -- 1 The ``No Clocks in Proks´´ Dogma -- 2 Data Dethroned the Dogma: Circadian Rhythms in Cyanobacteria -- 3 Establishing the Synechococcus elongatus PCC 7942 Model System -- References -- Part I: The Circadian Clock System in Cyanobacteria: Pioneer of Bacterial Clocks -- Around the Circadian Clock: Review and Preview -- 1 With Duckweed -- 2 At the National Institute for Basic Biology -- 3 Plant Physiology -- 4 Cloning of the per Gene -- 5 Phototaxis of Chlamydomonas reinhardtii -- 6 Sabbatical: Toward a New Experimental System for Circadian Clocks -- 7 Meeting Dr. Susan Golden -- 8 Whispers of Bioluminescence -- 9 Japan-USA Joint Research -- 10 Design and Fabrication of Bioluminescence Measurement System -- 11 Development of LCM and LCA: With Inside Macintosh -- 12 Mutant Screening and Complementation by Library -- 13 Discovery of the KaiABC Clock Gene Cluster -- 14 Return to Nagoya University -- 15 What ``Not to Do´´ -- 16 Cyanobacterial Transcription and Translation Model: Central Dogma in a Loop? -- 17 Obligate Photoautotrophy: Key to the Circadian Paradox -- 18 Reconstitution Experiment -- 19 Perfect Circadian Oscillation -- 20 The CI-ATPase Activity of KaiC Determines the Period -- 21 Review and Preview -- 22 Inside KaiC -- 23 Harmonic and Relaxation Oscillation -- 24 About Mechanical Clocks -- 25 Dual ATPases Coupling Model for KaiC Circadian Oscillator -- 26 ATPase Measurement -- 27 What Is the ``Tension that Determines the Period?´´ -- 28 Fundamental Frequency Problem -- 29 Acknowledgment -- 30 Editors´ Note.
A Retrospective: On Disproving the Transcription-Translation Feedback Loop Model in Cyanobacteria -- 1 Transcription-Translation Feedback Loop Model -- 2 Beyond the TTFL Model -- 3 Establishment of the In Vitro Reconstitution System -- References -- Mechanistic Aspects of the Cyanobacterial Circadian Clock -- Bibliography -- Mechanism of the Cyanobacterial Circadian Clock Protein KaiC to Measure 24 Hours -- 1 Introduction -- 2 Clock Systems of Cyanobacteria -- 3 Characteristics of the Circadian Clock in Terms of Temperature Compensation of Period -- 4 ATPase Activity and Intramolecular Feedback of KaiC -- 5 Stable Circadian Oscillations Due to Interactions Between Two ATPase Domains of KaiC -- 6 Design of Mechanical Clocks and the Design of Circadian Clocks -- 7 Conclusions -- References -- Oscillation and Input Compensation in the Cyanobacterial Kai Proteins -- 1 The Cyanobacterial Oscillator as a Biochemical Model for Chronobiology -- 2 Phenomenology of the Cyanobacterial Oscillator -- 3 Metabolic Input and Input Compensation -- 4 Phase Plane Picture of Input Compensation and Entrainment -- 5 A Toy Model with Integral Feedback Can Decouple Period and Amplitude -- 6 Period and Amplitude in the Model -- 7 Does KaiC Phosphorylation Implement Integral Feedback? -- 8 Coexistence of a Stable Fixed Point and a Limit Cycle -- 9 Conclusion -- References -- Insights into the Evolution of Circadian Clocks Gleaned from Bacteria -- 1 Evolution of Circadian Clocks: What Can Bacterial Clocks Tell Us? -- 2 General Considerations Concerning the Evolutionary Significance of Clocks -- 3 How and Why Did Bacteria Evolve Circadian Timekeepers? -- 4 Self-Sustained Versus Damped Oscillators Versus Hourglass Timers -- 5 Testing Whether Clocks Are Adaptive -- 6 Competition Experiments and Assessment of Fitness -- 7 ``It Takes a Village:´´ Communities and Populations. 8 A Medically Important Community: The Mammalian Gut Microbiome -- 9 Clocks Are Still Evolving! -- References -- Reasons for Seeking Information on the Molecular Structure and Dynamics of Circadian Clock Components in Cyanobacteria -- 1 Introduction -- 2 Narrowing a Research Question -- 3 Transmural Hierarchy -- 4 Structural Basis of Slowness in KaiC -- 5 From Intra- to Inter-Molecular Scales -- 6 Concluding Remarks -- References -- Single-Molecule Methods Applied to Circadian Proteins with Special Emphasis on Atomic Force Microscopy -- 1 Introduction -- 2 Single-Molecule Techniques -- 2.1 Single-Channel Patch-Clamp Recording -- 2.2 Single-Molecule Fluorescence Microscopy -- 2.3 Atomic Force Microscopy -- 2.3.1 HS-AFM Imaging -- 3 Visualizing Circadian Clock Proteins by HS-AFM -- 3.1 Experimental Conditions for HS-AFM Imaging of Kai Proteins -- 3.2 KaiA-KaiC Interaction -- 3.2.1 KaiA Interaction Depends upon KaiC Phosphostatus -- 3.2.2 Synchronous Oscillation of KaiA-KaiC Affinities with In Vitro Rhythm -- 3.2.3 Reinforcement of Oscillatory Resilience with PDDA -- 3.2.4 C-Terminal Tentacles of KaiC Hexamer Co-Operationally Bind to KaiA Dimer -- 3.3 KaiB-KaiC Interaction -- 3.3.1 Cooperative Binding of KaiB Monomers to KaiC Hexamer -- 3.3.2 KaiB Interaction Depends upon KaiC Phosphostatus -- 3.4 Visualization of KaiA-KaiB-KaiC Ternary Complex -- 4 Concluding Remarks -- References -- Diversity of Timing Systems in Cyanobacteria and Beyond -- 1 Introduction -- 2 Bioinformatics Analyses Reveal Diversity of Putative Clock Components in Cyanobacteria -- 2.1 The KaiABC Oscillator -- 2.2 The Circadian Protein Network Embedding the Core Clock -- 3 The Hourglass Timer -- 4 Synechocystis sp. PCC 6803: An Example of a Cyanobacterium Harboring Multiple Kai Homologs -- 4.1 Input and Output Pathways -- 4.2 The KaiB3C3 System. 4.3 Manipulation of Clock Components as a Strategy to Switch Metabolic Routes -- 5 Potential KaiC-Based Timing Systems Outside Cyanobacteria -- 6 Conclusion -- References -- An In Vitro Approach to Elucidating Clock-Modulating Metabolites -- 1 Basics of the Circadian-Oscillating KaiC Phosphorylation -- 2 Modulating the Circadian Clock with Adenosine Diphosphate (ADP) -- 3 Resetting the Clock Through Sensing the Redox State of Quinone -- 4 Regulating the KaiC Autokinase and Autophosphatase Activities with Mg2+ -- 5 Keeping Time with KaiC Alone as an Hourglass -- 6 Future Perspectives -- References -- Damped Oscillation in the Cyanobacterial Clock System -- 1 Introduction -- 2 Hopf Bifurcation Is a Scenario for Emerging Damped Oscillations -- 3 Low-Temperature MAKES In Vitro Rhythms Dampen Through Hopf Bifurcation -- 4 Resonance of the Damped Oscillation of KaiC During Temperature Cycles -- 5 Damped Oscillation in the Absence of KaiA -- 6 Evolution of Self-Sustained Oscillation -- 7 Summary -- References -- Roles of Phosphorylation of KaiC in the Cyanobacterial Circadian Clock -- 1 Introduction -- 2 Discovery of KaiC Phosphorylation -- 3 Relationship Between KaiC Phosphorylation and the Interaction Among Kai Proteins -- 4 ATP-Binding Sites Located at the Subunit Interfaces of KaiC Hexamer -- 5 In Vitro Reconstitution of a Circadian Oscillator -- 6 Sequential Phosphorylation of S431 and T432 -- 7 Discovery of ATPase Activity of KaiC -- 8 An Unusual Mechanism of KaiC Autodephosphorylation -- 9 Structural Basis for Time-Specific Interactions Among Kai Proteins -- 10 A Link Between KaiC Phosphorylation and Circadian Gene Expression -- 11 Multiple Output Systems of the Protein-Based Oscillator -- 12 Perspective -- References -- Reprogramming Metabolic Networks and Manipulating Circadian Clocks for Biotechnological Applications -- 1 Introduction. 2 Model Cyanobacterial Strains -- 3 Synthetic and Systems Biology in Cyanobacteria -- 4 Cyanobacterial Biofuels and Chemicals -- 4.1 Derivatives from Sugar Phosphates -- 4.2 Derivatives from DHAP -- 4.3 Derivatives from Pyruvate -- 4.4 Derivatives from Acetyl-CoA -- 4.5 Derivatives from TCA Cycle Metabolites -- 4.6 Derivatives from Amino Acids -- 4.7 Biomass Conversion -- 5 Modification of Cyanobacterial Framework for Improved Performance -- 5.1 Enhancing Photosynthetic Efficiency -- 5.2 Improving Carbon Assimilation -- 5.3 Rewiring the Central Carbon Metabolism -- 6 The Circadian Clock Regulates Gene Expression and Metabolism in Wild-Type Cyanobacteria -- 6.1 The Circadian Clock Governs Oscillation of Glycogen Content -- 6.2 The Circadian Oscillator Regulates Global Gene Expression and Metabolism -- 7 Global Complementary Regulation of Gene Expression Via Manipulation of the Clock -- 8 Manipulation of the Circadian Clock for Enhancing Expression of Foreign Genes -- 9 Conclusions and Prospects -- References -- Insights from Mathematical Modeling/Simulations of the In Vitro KaiABC Clock -- 1 Introduction -- 2 Insights from Simplified Phosphoform Dynamic Models -- 3 Hexamer Models and Allosteric Transitions -- References -- Part II: Circadian Phenomena in Microbiomes/Populations and Bacteria Besides Cyanobacteria -- Basic Biology of Rhythms and the Microbiome -- 1 Introduction -- 1.1 Circadian Rhythms in Mammals -- 1.2 Diurnal Rhythms of the Mammalian Microbiota -- 2 Circadian System in Host-Microbiome Interactions -- 2.1 Host Factors Shaping Microbiota Rhythms -- 2.2 The Influence of Microbiota on Host Rhythms and Metabolism -- 2.3 Perspectives and Challenges -- References -- Disease Implications of the Circadian Clocks and Microbiota Interface -- 1 Circadian Rhythms -- 2 Circadian Disruption. 3 Implications of Circadian Disruption and the Microbiota. |
| Record Nr. | UNINA-9910485606103321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Developmental biology in prokaryotes and lower eukaryotes / / Tomás González Villa, Trinidad de Miguel Bouzas, editors
| Developmental biology in prokaryotes and lower eukaryotes / / Tomás González Villa, Trinidad de Miguel Bouzas, editors |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (560 pages) |
| Disciplina | 571.8 |
| Soggetto topico |
Developmental biology
Procariotes Protists Biologia del desenvolupament |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-77595-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910495174803321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
RNA damage and repair / / Ioly Kotta-Loizou, editor
| RNA damage and repair / / Ioly Kotta-Loizou, editor |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (180 pages) |
| Disciplina | 572.88 |
| Soggetto topico |
RNA
DNA damage ADN Reparació de l'ADN Biomolècules Procariotes |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-76571-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- Part I: RNA Damage and Repair in Prokaryotes -- Endoribonucleases of the Toxin-Antitoxin Systems Induce Abortive Infection -- 1 Introduction -- 1.1 The Arms Race Between Bacteria and Phages -- 1.2 The Abortive Infection (Abi) System -- 1.3 The Toxin-Antitoxin (TA) System -- 2 Functions, Structures, and Regulation of the MazF Endoribonuclease -- 2.1 The Abortive Infection Induced by the MazF Endoribonuclease -- 2.2 Phage Mechanism to Overcome MazF-Induced Abi -- 3 Functions, Structures, and Regulation of RnlA Endoribonuclease -- 3.1 The Abortive Infection Induced by RnlA Endoribonuclease -- 3.2 Phage Mechanisms to Overcome RnlA-Induced Abi -- 4 Functions, Structures, and Regulations of ToxN Endoribonuclease -- 4.1 The Abortive Infection Induced by ToxN Endoribonuclease -- 4.2 Phage Mechanisms to Overcome ToxN-Induced Abi -- 5 Conclusion -- References -- The Lifecycle of Ribosomal RNA in Bacteria -- 1 Introduction -- 2 Localisation and Copy Number of rDNA Operons in Bacteria -- 3 Organisation of rDNA Operons in Bacteria -- 4 Transcription Regulation of rDNA Genes Along the Microbial Growth Curve -- 4.1 Ribosomal DNA Promoters and Cis-Regulatory Elements -- 4.2 Trans-regulatory Elements -- 4.2.1 Regulation by Transcription Factors -- 4.2.2 Regulation by NTP and (p)ppGpp -- 5 Processing of Premature rRNA into Functional rRNAs -- 5.1 Maturation of 23S rRNA in E. coli -- 5.2 Maturation of 16S rRNA in E. coli -- 5.3 Maturation of 5S rRNA in E. coli -- 6 Bacterial rRNA Fragmentation -- 7 Chemical Modification of rRNA Molecules -- 8 Assembly of rRNAs into Ribosomes -- 9 rRNA Quality Control -- 10 Damage and Repair of Bacterial rRNA -- 11 Conclusion -- References -- The Rtc RNA End Healing and Sealing System -- 1 Introduction -- 2 Biological RNA Damage -- 2.1 CRISPR-Cas Systems -- 3 RNA Repair -- 4 The RtcA and RtcB Enzymes.
4.1 The RtcA RNA Cyclase -- 4.2 The RtcB RNA Ligase -- 4.3 The RtcB RNA Ligase in Prokaryotes -- 4.4 The RtcB RNA Ligase in Metazoans -- 5 The Bacterial Rtc RNA Repair System -- 5.1 Diversity of the rtc Operon in Bacteria -- 5.2 The RtcR Transcriptional Regulator and Its CARF Domain -- 5.3 Expression and Function of the Rtc System in Bacteria -- 6 Conclusions -- References -- Part II: RNA Damage and Repair in Eukaryotes -- Oxidative and Nitrative RNA Modifications in Plants -- 1 Introduction -- 2 Oxidative Modifications of RNA in Plants -- 3 Nitrative Modifications of RNA in Plants -- 4 Conclusions -- References -- The Role of Ribonucleases in RNA Damage, Inactivation and Degradation -- 1 Introduction -- 2 Quality Control Mechanisms to Manage Damaged RNA -- 3 Ribosome Quality Control (RQC) and No-Go-Decay (NGD) -- 4 Xrn1, a 5'-3' Exoribonuclease, and the Exosome, a 3'-5' Exoribonuclease Complex -- 5 Cue2 as a Potential NGD Endonuclease -- 6 The Role of Ribonucleases in Targeting and Inactivating Host and Foreign RNA -- 7 Regulatory RNase 1 (Regnase-1) -- 8 NEDD4-Binding Protein 1 (N4BP1) -- 9 Zinc Finger Antiviral Protein (ZAP) and Co-Factor Nucleases -- 10 ZAP and KHNYN -- 11 ZAP and the Exosome Complex -- 12 The 2',5'-Oligoadenylate Synthetase (OAS)/RNAse L System -- 13 Conclusion -- References -- Cytoplasmic mRNA Recapping: An Unexpected Form of RNA Repair -- 1 The Nature of the Cap and Its Role in mRNA Metabolism -- 2 Decapping and 5' Decay -- 3 Early Evidence for Uncapped and Recapped Transcripts -- 4 The Discovery of Cytoplasmic Capping -- 5 The Proteins of the Cytoplasmic Capping Complex -- 6 Cap Homeostasis as an RNA Repair Mechanism That Modulates Translation, mRNA Decay, and Translational Control -- 7 Is There a Relationship Between Recapped Ends and CAGE Tags? -- 8 Does Cytoplasmic Capping Impact the Proteome?. 9 Conclusion and Future Questions -- References -- Part III: RNA Damage in Human Diseases -- Adenosine-to-Inosine RNA Editing: A Key RNA Processing Step Rewriting Transcriptome in Normal Physiology and Diseases -- 1 Regulatory Mechanisms of A-to-I RNA Editing -- 1.1 Editing Regulation by Altering ADAR Expression and Activity -- 1.2 Editing Regulation by Affecting Subcellular Localization of ADAR -- 1.3 Additional Layers of A-to-I RNA Editing Regulation -- 2 Cross Talk of RNA Editing with Other RNA Processing and Cellular Pathways -- 2.1 Roles of ADARs and RNA Editing in miRNA Targeting and Biogenesis -- 2.2 ADARs and Splicing Regulation -- 2.3 ADAR Directly Promotes Proximal Polyadenylation Site -- 2.4 ADAR and N6-Methyladenosine -- 2.5 ADAR and Apoptosis -- 2.6 ADAR and Innate Immunity -- 2.7 ADAR2 and Circadian Rhythm -- References -- RNA-Mediated Metabolic Defects in Microsatellite Expansion Diseases -- 1 Overview of Microsatellite Expansion Diseases -- 2 RNA Structure and RNA-Mediated Toxicity -- 3 Repeat Associated Non-AUG Translation -- 4 Emerging Pathological Roles of microRNA -- 5 Defects in Nucleocytoplasmic Transport -- 6 Liquid-Liquid Phase Separation (LLPS) and Stress Granules -- 7 Conclusions and Future Perspectives -- References. |
| Record Nr. | UNINA-9910490024403321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
