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Fatal flaws [[electronic resource] ] : how a misfolded protein baffled scientists and changed the way we look at the brain / / Jay Ingram
| Fatal flaws [[electronic resource] ] : how a misfolded protein baffled scientists and changed the way we look at the brain / / Jay Ingram |
| Autore | Ingram Jay |
| Pubbl/distr/stampa | New Haven, : Yale University Press, 2013 |
| Descrizione fisica | 1 online resource (293 p.) |
| Disciplina | 616.8/3 |
| Soggetto topico |
Prions
Prion diseases |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-299-28410-8
0-300-19518-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910465857903321 |
Ingram Jay
|
||
| New Haven, : Yale University Press, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Fatal flaws [[electronic resource] ] : how a misfolded protein baffled scientists and changed the way we look at the brain / / Jay Ingram
| Fatal flaws [[electronic resource] ] : how a misfolded protein baffled scientists and changed the way we look at the brain / / Jay Ingram |
| Autore | Ingram Jay |
| Pubbl/distr/stampa | New Haven, : Yale University Press, 2013 |
| Descrizione fisica | 1 online resource (293 p.) |
| Disciplina | 616.8/3 |
| Soggetto topico |
Prions
Prion diseases |
| ISBN |
1-299-28410-8
0-300-19518-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The mystery of kuru : a disease like no other -- Barflies and flatworms : how speculation and pure chance advance a new science -- Cannibalism : an answer guaranteed to stir things up -- Igor and Bill : the discoveries that bring kuru to world attention -- The life of a cell : a miraculous, and often precarious, complexity -- The death of a cell : by subterfuge, piracy, or out-and-out assault -- When is a virus not a virus? : when a disease-causing agent reproduces without genes -- Creutzfeldt-Jakob disease : waking up to the potential of a devastating affliction -- Magnificent molecules : the proteins that make life possible -- Protein origami : building the gothic cathedrals of life -- Stanley Prusiner's Heresy : an infectious agent that's a protein and nothing but -- An infectious idea : the campaign for the minds of researchers -- A portrait of the prion : and the experiments that point to their role in the human brain -- Mad cow disease : the uncertain ground where politics and science intersect -- Mad cow in humans : no barrier after all -- The Americas : mad mink, then cows -- Into the wild : deer, elk, moose, and caribou -- Origins : attempting to find where prions come from -- Cats but not dogs : when prions jump the species barrier -- Alzheimer's disease : plaques and tangles but so far no prions -- Parkinson's disease : looking more and more like a prion disease -- Lou Gehrig's disease : the emerging picture of a prion-like process in ALS -- Chronic traumatic encephalopathy : the athletes' plague -- And in the end... |
| Record Nr. | UNINA-9910792050503321 |
|
Ingram Jay
|
||
| New Haven, : Yale University Press, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Fatal flaws : how a misfolded protein baffled scientists and changed the way we look at the brain / / Jay Ingram
| Fatal flaws : how a misfolded protein baffled scientists and changed the way we look at the brain / / Jay Ingram |
| Autore | Ingram Jay |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | New Haven, : Yale University Press, 2013 |
| Descrizione fisica | 1 online resource (293 p.) |
| Disciplina | 616.8/3 |
| Soggetto topico |
Prions
Prion diseases |
| ISBN |
1-299-28410-8
0-300-19518-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The mystery of kuru : a disease like no other -- Barflies and flatworms : how speculation and pure chance advance a new science -- Cannibalism : an answer guaranteed to stir things up -- Igor and Bill : the discoveries that bring kuru to world attention -- The life of a cell : a miraculous, and often precarious, complexity -- The death of a cell : by subterfuge, piracy, or out-and-out assault -- When is a virus not a virus? : when a disease-causing agent reproduces without genes -- Creutzfeldt-Jakob disease : waking up to the potential of a devastating affliction -- Magnificent molecules : the proteins that make life possible -- Protein origami : building the gothic cathedrals of life -- Stanley Prusiner's Heresy : an infectious agent that's a protein and nothing but -- An infectious idea : the campaign for the minds of researchers -- A portrait of the prion : and the experiments that point to their role in the human brain -- Mad cow disease : the uncertain ground where politics and science intersect -- Mad cow in humans : no barrier after all -- The Americas : mad mink, then cows -- Into the wild : deer, elk, moose, and caribou -- Origins : attempting to find where prions come from -- Cats but not dogs : when prions jump the species barrier -- Alzheimer's disease : plaques and tangles but so far no prions -- Parkinson's disease : looking more and more like a prion disease -- Lou Gehrig's disease : the emerging picture of a prion-like process in ALS -- Chronic traumatic encephalopathy : the athletes' plague -- And in the end... |
| Altri titoli varianti | How a misfolded protein baffled scientists and changed the way we look at the brain |
| Record Nr. | UNINA-9910810651003321 |
|
Ingram Jay
|
||
| New Haven, : Yale University Press, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Novel infectious agents and the central nervous system [[electronic resource]]
| Novel infectious agents and the central nervous system [[electronic resource]] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1988 |
| Descrizione fisica | 1 online resource (290 p.) |
| Disciplina |
616.8
616.83 |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Central nervous system - Diseases - Etiology
Scrapie Prions |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-34597-4
9786612345975 0-470-51361-6 0-470-51362-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
NOVEL INFECTIOUS AGENTSANDTHE CENTRAL NERVOUS SYSTEM; Contents; Participants; Introduction; The clinical neurology and epidemiology of Creutzfeldt-Jakob disease, with special reference to iatrogenic cases; Neuropathology of unconventional virus infections: molecu lar pathology of spongiform change and amyloid plaque deposit ion; Pathogenesis of experimental scrapie; Genetic aspects of unconventional virus infections: the basis of the virino hypothesis; Genetic control of prion incubation period in mice; Developmental regulation of prion protein mRNA in brain
Potential involvement of retroviral elements in human dementiasScrapie: a virus-induced amyloidosis of the brain; Scrapie-associated fibrils, PrP protein and the Sinc gene; A modified host protein model of scrapie; Properties of scrapie prion proteins in liposomes and amyloid rods; In vitro expression of cloned PrP cDNA derived from scrapie-infected mouse brain: lack of transmission of scrapie infectivity; Search for a scrapie-specific nucleic acid: a progress report; Pathogenesis of amyloid formation in Alzheimer's disease, Down's syndrome and scrapie Novel mechanisms of degeneration of the central newous system - prion structure and biologyFinal general discussion; Summary; Index of contributors; Subject index |
| Record Nr. | UNINA-9910144728603321 |
| Chichester ; ; New York, : Wiley, 1988 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Novel infectious agents and the central nervous system [[electronic resource]]
| Novel infectious agents and the central nervous system [[electronic resource]] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1988 |
| Descrizione fisica | 1 online resource (290 p.) |
| Disciplina |
616.8
616.83 |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Central nervous system - Diseases - Etiology
Scrapie Prions |
| ISBN |
1-282-34597-4
9786612345975 0-470-51361-6 0-470-51362-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
NOVEL INFECTIOUS AGENTSANDTHE CENTRAL NERVOUS SYSTEM; Contents; Participants; Introduction; The clinical neurology and epidemiology of Creutzfeldt-Jakob disease, with special reference to iatrogenic cases; Neuropathology of unconventional virus infections: molecu lar pathology of spongiform change and amyloid plaque deposit ion; Pathogenesis of experimental scrapie; Genetic aspects of unconventional virus infections: the basis of the virino hypothesis; Genetic control of prion incubation period in mice; Developmental regulation of prion protein mRNA in brain
Potential involvement of retroviral elements in human dementiasScrapie: a virus-induced amyloidosis of the brain; Scrapie-associated fibrils, PrP protein and the Sinc gene; A modified host protein model of scrapie; Properties of scrapie prion proteins in liposomes and amyloid rods; In vitro expression of cloned PrP cDNA derived from scrapie-infected mouse brain: lack of transmission of scrapie infectivity; Search for a scrapie-specific nucleic acid: a progress report; Pathogenesis of amyloid formation in Alzheimer's disease, Down's syndrome and scrapie Novel mechanisms of degeneration of the central newous system - prion structure and biologyFinal general discussion; Summary; Index of contributors; Subject index |
| Record Nr. | UNINA-9910830012003321 |
| Chichester ; ; New York, : Wiley, 1988 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Novel infectious agents and the central nervous system
| Novel infectious agents and the central nervous system |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1988 |
| Descrizione fisica | 1 online resource (290 p.) |
| Disciplina |
616.8
616.83 |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Central nervous system - Diseases - Etiology
Scrapie Prions |
| ISBN |
1-282-34597-4
9786612345975 0-470-51361-6 0-470-51362-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
NOVEL INFECTIOUS AGENTSANDTHE CENTRAL NERVOUS SYSTEM; Contents; Participants; Introduction; The clinical neurology and epidemiology of Creutzfeldt-Jakob disease, with special reference to iatrogenic cases; Neuropathology of unconventional virus infections: molecu lar pathology of spongiform change and amyloid plaque deposit ion; Pathogenesis of experimental scrapie; Genetic aspects of unconventional virus infections: the basis of the virino hypothesis; Genetic control of prion incubation period in mice; Developmental regulation of prion protein mRNA in brain
Potential involvement of retroviral elements in human dementiasScrapie: a virus-induced amyloidosis of the brain; Scrapie-associated fibrils, PrP protein and the Sinc gene; A modified host protein model of scrapie; Properties of scrapie prion proteins in liposomes and amyloid rods; In vitro expression of cloned PrP cDNA derived from scrapie-infected mouse brain: lack of transmission of scrapie infectivity; Search for a scrapie-specific nucleic acid: a progress report; Pathogenesis of amyloid formation in Alzheimer's disease, Down's syndrome and scrapie Novel mechanisms of degeneration of the central newous system - prion structure and biologyFinal general discussion; Summary; Index of contributors; Subject index |
| Record Nr. | UNINA-9910876518203321 |
| Chichester ; ; New York, : Wiley, 1988 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Prion
| Prion |
| Pubbl/distr/stampa | Austin, Tex., : Landes Bioscience |
| Disciplina | 616 |
| Soggetto topico |
Prions
Protein folding Protein Folding |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 1933-690X |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996209905703316 |
| Austin, Tex., : Landes Bioscience | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Prion
| Prion |
| Pubbl/distr/stampa | Austin, Tex., : Landes Bioscience |
| Disciplina | 616 |
| Soggetto topico |
Prions
Protein folding Protein Folding |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 1933-690X |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910146897103321 |
| Austin, Tex., : Landes Bioscience | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Prion biology and diseases [[electronic resource] /] / edited by Stanley B. Prusiner
| Prion biology and diseases [[electronic resource] /] / edited by Stanley B. Prusiner |
| Pubbl/distr/stampa | Cold Spring Harbor, N.Y., : Cold Spring Harbor Laboratory Press, 1999 |
| Descrizione fisica | 1 online resource (809 p.) |
| Disciplina | 616.8/3 |
| Altri autori (Persone) | PrusinerStanley B. <1942-> |
| Collana | Cold Spring Harbor monograph series |
| Soggetto topico |
Prions
Prion diseases |
| Soggetto genere / forma | Electronic books. |
| ISBN | 0-87969-656-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910456148703321 |
| Cold Spring Harbor, N.Y., : Cold Spring Harbor Laboratory Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Prion biology and diseases / / editor, Stanley B. Prusiner
| Prion biology and diseases / / editor, Stanley B. Prusiner |
| Pubbl/distr/stampa | Cold Spring Harbor, N.Y. : , : Cold Spring Harbor Laboratory Press, , 1999 |
| Descrizione fisica | 1 online resource (xiii, 794 pages) : illustrations (some color) |
| Disciplina | 616.8/3 |
| Altri autori (Persone) | PrusinerStanley B. <1942-> |
| Collana | Cold Spring Harbor monograph series |
| Soggetto topico |
Prions
Prion diseases |
| ISBN | 0-87969-656-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. An Introduction to Prion Biology and Diseases / S.B. Prusiner 2. Development of the Prion Concept / S.B. Prusiner 3. Bioassays of Prions / S.B. Prusiner, P. Tremblay and J. Safar / [and others] 4. Transmission and Replication of Prions / S.B. Prusiner, M.R. Scott and S.J. DeArmond / [and othe rs]5. Structural Studies of Prion Proteins / F.E. Cohen and S.B. PrusinerFungal Prions6. Prions of Fungi: [URE3], [PSI], and [Het-s] Discovered as Heritable Traits / R.B. Wickner and Y.O. ChernoffTransgenetics and Cell Biology of Prions7. Knockouts, Transgenics, and Transplants in Prion Research / C. Weissmann, A.J. Raeber and D. Shmerling / [et al.]8. Transgenetic Investigations of the Species Barrier and Prion Strains / M. Scott, S.J. DeArmond and S.B. Prusiner / [et al.]9. Cell Biology of Prions / S.B. Prusiner, P. Peters and K. Kaneko / [et al.]Prion Diseases in Animals10. Scrapie, Chronic Wasting Disease, and Transmissible Mink Encephalopathy / J.-L. Laplanche, N. Hunter and M. Shinagawa / [et al.]11. Bovine Spongiform Encephalopathy and Related Diseases / N. Nathanson, J. Wilesmith and G.A. Wells / [et al.]Human Prion Diseases12. Infectious and Sporadic Prion Diseases / R.G. Will, M.P. Alpers and D. Dormont / [et al.]13. Inherited Prion Diseases / P. Gambetti, R.B. Petersen and P. Parchi / [et al.]14. Neuropathology of Prion Diseases / S.J. DeArmond and J.W. IronsideMethodology and Future Studies15. Some Strategies and Methods for the Study of Prions / S.B. Prusiner, K. Kaneko and H. Serban / [et al.]16. Antibodies as Tools to Probe Prion Protein Biology / R.A. Williamson, D.R. Burton and D. Peretz / [et al.]17. Biosafety Issues in Prion Diseases / H. Baron, J. Safar and D. Groth / [et al.] |
| Record Nr. | UNINA-9910780170103321 |
| Cold Spring Harbor, N.Y. : , : Cold Spring Harbor Laboratory Press, , 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Prions
(23)
- Prion diseases (17)
- Central nervous system - Diseases - Etiology (3)
- Scrapie (3)
- Protein Folding (2)