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The hERG cardial potassium channel [[electronic resource] ] : structure, function, and long QT syndrome / / [editors, Derek J. Chadwick, James Goode]
| The hERG cardial potassium channel [[electronic resource] ] : structure, function, and long QT syndrome / / [editors, Derek J. Chadwick, James Goode] |
| Pubbl/distr/stampa | New York, : J. Wiley, 2005 |
| Descrizione fisica | 1 online resource (309 p.) |
| Disciplina |
612.1/7
612.173 616.1207 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Potassium channels
Long QT syndrome Heart - Physiology Heart - Pathophysiology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-27526-X
9786610275267 0-470-02142-X 0-470-02141-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
THE hERG CARDIAC POTASSIUM CHANNEL: STRUCTURE, FUNCTION AND LONG QT SYNDROME; Contents; Participants; Chair's introduction; Gating and assembly of heteromeric hERG1a/1b channels underlying I(Kr) in the heart; Discussion; Structure-function studies of the outer mouth and voltage sensor domain of hERG; Discussion; General discussion I; Voltage sensor movement in the hERGK(+) channel; Discussion; hERG channel trafficking; Discussion; Dynamic control of hERG/I(Kr) by PKA-mediated interactions with 14-3-3; Discussion; General discussion II
Does hERG coassemble with a b subunit? Evidence for roles of MinK and MiRP1Discussion; hERG block, QT liability and sudden cardiac death; Discussion; Structural determinants for high-affinity block of hERG potassium channels; Discussion; Physicochemical basis for binding and voltage-dependent block of hERG channels by structurally diverse drugs; Discussion; In silico modelling-pharmacophores and hERG channel models; Discussion; The long QTsyndrome: a clinical counterpart of HERG mutations; Discussion; Cellular mechanisms of Torsade de Pointes; Discussion Expression and role of hERG channels in cancer cellsDiscussion; TRIad: foundation for proarrhythmia (triangulation, reverse use dependence and instability); Discussion; Drug-induced QT interval prolongation: regulatory guidance and perspectives on hERG channel studies; Discussion; Closing remarks; Index of contributors; Subject index |
| Record Nr. | UNINA-9910143740603321 |
| New York, : J. Wiley, 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The hERG cardial potassium channel : structure, function, and long QT syndrome / / [editors, Derek J. Chadwick, James Goode]
| The hERG cardial potassium channel : structure, function, and long QT syndrome / / [editors, Derek J. Chadwick, James Goode] |
| Pubbl/distr/stampa | New York, : J. Wiley, 2005 |
| Descrizione fisica | 1 online resource (309 p.) |
| Disciplina | 612.1/7 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Potassium channels
Long QT syndrome Heart - Physiology Heart - Pathophysiology |
| ISBN |
9786610275267
9781280275265 128027526X 9780470021422 047002142X 9780470021415 0470021411 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
THE hERG CARDIAC POTASSIUM CHANNEL: STRUCTURE, FUNCTION AND LONG QT SYNDROME; Contents; Participants; Chair's introduction; Gating and assembly of heteromeric hERG1a/1b channels underlying I(Kr) in the heart; Discussion; Structure-function studies of the outer mouth and voltage sensor domain of hERG; Discussion; General discussion I; Voltage sensor movement in the hERGK(+) channel; Discussion; hERG channel trafficking; Discussion; Dynamic control of hERG/I(Kr) by PKA-mediated interactions with 14-3-3; Discussion; General discussion II
Does hERG coassemble with a b subunit? Evidence for roles of MinK and MiRP1Discussion; hERG block, QT liability and sudden cardiac death; Discussion; Structural determinants for high-affinity block of hERG potassium channels; Discussion; Physicochemical basis for binding and voltage-dependent block of hERG channels by structurally diverse drugs; Discussion; In silico modelling-pharmacophores and hERG channel models; Discussion; The long QTsyndrome: a clinical counterpart of HERG mutations; Discussion; Cellular mechanisms of Torsade de Pointes; Discussion Expression and role of hERG channels in cancer cellsDiscussion; TRIad: foundation for proarrhythmia (triangulation, reverse use dependence and instability); Discussion; Drug-induced QT interval prolongation: regulatory guidance and perspectives on hERG channel studies; Discussion; Closing remarks; Index of contributors; Subject index |
| Record Nr. | UNINA-9911019323903321 |
| New York, : J. Wiley, 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pharmacology of potassium channels / / Nikita Gamper, KeWei Wang, editors
| Pharmacology of potassium channels / / Nikita Gamper, KeWei Wang, editors |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (546 pages) |
| Disciplina | 546.383 |
| Collana | Handbook of experimental pharmacology |
| Soggetto topico |
Potassium channels
Canals de potassi Farmacologia |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-84052-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910502660503321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Potassium channels [[electronic resource] ] : types, structure and blockers / / Danielle S. Fonseca, editor
| Potassium channels [[electronic resource] ] : types, structure and blockers / / Danielle S. Fonseca, editor |
| Pubbl/distr/stampa | Hauppauge, N.Y., : Nova Biomedical Books, c2012 |
| Descrizione fisica | 1 online resource (159 p.) |
| Disciplina | 547/.05383 |
| Altri autori (Persone) | FonsecaDanielle S |
| Collana | Cell biology research progress |
| Soggetto topico | Potassium channels |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-61470-024-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Potassium channels and vascular tone : structure, regulation, and function / Elisa Cairrão, Ignacio Verde -- The contribution of lymphocyte potassium channels to the perinatal regulation of the immune response in mother and newborn / Gergely Toldi, Barna Vásárhelyi -- Mitochondrial potassium channel : feature and physiological participation / R. Milan, F. Martinez -- Slow potassium channel dysfunction in amyotrophic lateral sclerosis and its in vivo evaluation by threshold tracking / Hiroyuki Nodera -- Characteristics of potassium channels of smooth muscle in health and disease / Yasushi Sakai, Michio Hashimoto -- Individual potassium channel proteins display characteristic patterns in rate cerebellum and olfactory bulb / Angelike Gortzen ... [et al.] -- Plant mitochondrial potassium channel or channels / Donato Pastore, Maura Nicoletta Laus, Mario Soccio -- Involvement of the mitochondrial ATP-sensitive potassium channel in the beneficial effects of fasting on the ischemic-referfused rat heart / M.G. Marina Prendes ... [et al.]. |
| Record Nr. | UNINA-9910453026903321 |
| Hauppauge, N.Y., : Nova Biomedical Books, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Potassium channels [[electronic resource] ] : types, structure and blockers / / Danielle S. Fonseca, editor
| Potassium channels [[electronic resource] ] : types, structure and blockers / / Danielle S. Fonseca, editor |
| Pubbl/distr/stampa | Hauppauge, N.Y., : Nova Biomedical Books, c2012 |
| Descrizione fisica | 1 online resource (159 p.) |
| Disciplina | 547/.05383 |
| Altri autori (Persone) | FonsecaDanielle S |
| Collana | Cell biology research progress |
| Soggetto topico | Potassium channels |
| ISBN | 1-61470-024-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Potassium channels and vascular tone : structure, regulation, and function / Elisa Cairrão, Ignacio Verde -- The contribution of lymphocyte potassium channels to the perinatal regulation of the immune response in mother and newborn / Gergely Toldi, Barna Vásárhelyi -- Mitochondrial potassium channel : feature and physiological participation / R. Milan, F. Martinez -- Slow potassium channel dysfunction in amyotrophic lateral sclerosis and its in vivo evaluation by threshold tracking / Hiroyuki Nodera -- Characteristics of potassium channels of smooth muscle in health and disease / Yasushi Sakai, Michio Hashimoto -- Individual potassium channel proteins display characteristic patterns in rate cerebellum and olfactory bulb / Angelike Gortzen ... [et al.] -- Plant mitochondrial potassium channel or channels / Donato Pastore, Maura Nicoletta Laus, Mario Soccio -- Involvement of the mitochondrial ATP-sensitive potassium channel in the beneficial effects of fasting on the ischemic-referfused rat heart / M.G. Marina Prendes ... [et al.]. |
| Record Nr. | UNINA-9910779798603321 |
| Hauppauge, N.Y., : Nova Biomedical Books, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Potassium channels : types, structure and blockers / / Danielle S. Fonseca, editor
| Potassium channels : types, structure and blockers / / Danielle S. Fonseca, editor |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hauppauge, N.Y., : Nova Biomedical Books, c2012 |
| Descrizione fisica | 1 online resource (159 p.) |
| Disciplina | 547/.05383 |
| Altri autori (Persone) | FonsecaDanielle S |
| Collana | Cell biology research progress |
| Soggetto topico | Potassium channels |
| ISBN | 1-61470-024-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Potassium channels and vascular tone : structure, regulation, and function / Elisa Cairrão, Ignacio Verde -- The contribution of lymphocyte potassium channels to the perinatal regulation of the immune response in mother and newborn / Gergely Toldi, Barna Vásárhelyi -- Mitochondrial potassium channel : feature and physiological participation / R. Milan, F. Martinez -- Slow potassium channel dysfunction in amyotrophic lateral sclerosis and its in vivo evaluation by threshold tracking / Hiroyuki Nodera -- Characteristics of potassium channels of smooth muscle in health and disease / Yasushi Sakai, Michio Hashimoto -- Individual potassium channel proteins display characteristic patterns in rate cerebellum and olfactory bulb / Angelike Gortzen ... [et al.] -- Plant mitochondrial potassium channel or channels / Donato Pastore, Maura Nicoletta Laus, Mario Soccio -- Involvement of the mitochondrial ATP-sensitive potassium channel in the beneficial effects of fasting on the ischemic-referfused rat heart / M.G. Marina Prendes ... [et al.]. |
| Record Nr. | UNINA-9910964893303321 |
| Hauppauge, N.Y., : Nova Biomedical Books, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Potassium channels as a target for clinical therapeutics / / edited by Ivan Kocić
| Potassium channels as a target for clinical therapeutics / / edited by Ivan Kocić |
| Autore | Kocic Ivan |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Dubai, United Arab Emirates, : Bentham eBooks, [2012] |
| Descrizione fisica | 1 online resource (104 p.) |
| Disciplina | 581.1 |
| Altri autori (Persone) | KocićIvan |
| Soggetto topico |
Potassium channels
Potassium in the body Potassium - Physiological effect |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 01 Title.pdf; 02 Cover Page; 03 REVISED eBooks End User License Agreement-Website; 04 Dedication; 05 Content; 06 Foreword; 07 Preface; 08 List of Contributors; 09 Chapter 01; 10 Chapter 02; 11 Chapter 03; 12 Chapter 04; 13 Chapter 05; 14 Glossary; 15 Index |
| Record Nr. | UNINA-9910974358603321 |
Kocic Ivan
|
||
| Dubai, United Arab Emirates, : Bentham eBooks, [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Potassium channels as a target for clinical therapeutics [[electronic resource] /] / edited by Ivan Kocić
| Potassium channels as a target for clinical therapeutics [[electronic resource] /] / edited by Ivan Kocić |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Dubai, United Arab Emirates, : Bentham eBooks, [2012] |
| Descrizione fisica | 1 online resource (104 p.) |
| Disciplina | 581.1 |
| Altri autori (Persone) | KocićIvan |
| Soggetto topico |
Potassium channels
Potassium in the body Potassium - Physiological effect |
| Soggetto genere / forma | Electronic books. |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 01 Title.pdf; 02 Cover Page; 03 REVISED eBooks End User License Agreement-Website; 04 Dedication; 05 Content; 06 Foreword; 07 Preface; 08 List of Contributors; 09 Chapter 01; 10 Chapter 02; 11 Chapter 03; 12 Chapter 04; 13 Chapter 05; 14 Glossary; 15 Index |
| Record Nr. | UNINA-9910451639003321 |
| Dubai, United Arab Emirates, : Bentham eBooks, [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Potassium channels as a target for clinical therapeutics [[electronic resource] /] / edited by Ivan Kocić
| Potassium channels as a target for clinical therapeutics [[electronic resource] /] / edited by Ivan Kocić |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Dubai, United Arab Emirates, : Bentham eBooks, [2012] |
| Descrizione fisica | 1 online resource (104 p.) |
| Disciplina | 581.1 |
| Altri autori (Persone) | KocićIvan |
| Soggetto topico |
Potassium channels
Potassium in the body Potassium - Physiological effect |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 01 Title.pdf; 02 Cover Page; 03 REVISED eBooks End User License Agreement-Website; 04 Dedication; 05 Content; 06 Foreword; 07 Preface; 08 List of Contributors; 09 Chapter 01; 10 Chapter 02; 11 Chapter 03; 12 Chapter 04; 13 Chapter 05; 14 Glossary; 15 Index |
| Record Nr. | UNINA-9910779193703321 |
| Dubai, United Arab Emirates, : Bentham eBooks, [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Structure to function of G protein-gated inwardly rectifying (GIRK) channels / / Paul A. Slesinger, Kevin Wickman
| Structure to function of G protein-gated inwardly rectifying (GIRK) channels / / Paul A. Slesinger, Kevin Wickman |
| Autore | Slesinger Paul A. |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | Amsterdam, [Netherlands] : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (0 p.) |
| Disciplina | 572.643 |
| Collana | International Review of Neurobiology |
| Soggetto topico |
G proteins
Potassium channels |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-12-802458-5
0-12-802631-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910460924503321 |
|
Slesinger Paul A.
|
||
| Amsterdam, [Netherlands] : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
