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Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders / / by Shabir Ahmad Ganai
| Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders / / by Shabir Ahmad Ganai |
| Autore | Ganai Shabir Ahmad |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (XVII, 93 p. 8 illus., 5 illus. in color.) |
| Disciplina | 612.8 |
| Soggetto topico |
Neurosciences
Pharmacology Genetics Proteins Posttranslational modification Pharmacology/Toxicology Genetics and Genomics Protein Science Posttranslational Modification |
| ISBN | 981-13-8019-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Role of Epigenetics in neurological diseases -- Chapter 2. Epigenetic enzymes and the drawbacks of conventional therapeutic regimens -- Chapter 3. Distinct classes of HDACs -- Chapter 4. HDAC implications in neurological diseases -- Chapter 5. HDAC inhibitors and their structurally distinct groups -- Chapter 6. HDAC inhibitors as novel therapeutic option against therapeutically challenging neurological disorders -- Chapter 7. Current Challenges with HDAC inhibitor based therapeutic intervention against neurological maladies -- Chapter 8. Escalating need of isoform selective inhibitors for enhanced therapeutic efficacy -- Chapter 9. Combinatorial therapeutic regimens using HDAC inhibitors in conjunction with conventional therapeutic agents -- Chapter 10. Future directions of epigenetic research in tackling neurological complications. |
| Record Nr. | UNINA-9910350356103321 |
Ganai Shabir Ahmad
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| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Histone Recognition / / edited by Ming-Ming Zhou
| Histone Recognition / / edited by Ming-Ming Zhou |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (284 p.) |
| Disciplina |
572.6
610 611.01816 |
| Soggetto topico |
Gene expression
Posttranslational modification Proteins Medical genetics Gene Expression Posttranslational Modification Protein-Ligand Interactions Gene Function |
| ISBN | 3-319-18102-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The Bromodomain as the Acetyl-Lysine Binding Domain in Gene Transcription -- PHD Fingers as Histone Readers -- Methyl-Lysine Recognition by the Royal Family Modules: Chromo, Tudor, MBT, Chromo Barrel, and PWWP Domains -- Histone Recognition by WD40 Proteins -- Methyl-Lys Recognition by Ankyrin Repeat Proteins -- Methyl-Arginine Recognition by Tudor Domains -- Histone Recognition by Tandem Modules and Modulation by Multiple PTMs -- Genome-Wide Profiling of Molecular Recognition of Histone PTMs -- BET Bromodomain Inhibition as a Therapeutic Approach in Hematological Malignancies -- Anti-Inflammatory Effects of BET Protein Inhibition Through Modulation of Gene Transcription -- Activating Latent HIV by Inhibiting Bromodomain Proteins -- Small Molecule Modulation of Methyl-Lysine Mediated Interactions. |
| Record Nr. | UNINA-9910298296503321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Immune Metabolism in Health and Tumor / / edited by Bin Li, Fan Pan
| Immune Metabolism in Health and Tumor / / edited by Bin Li, Fan Pan |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (V, 223 p. 24 illus., 23 illus. in color.) |
| Disciplina | 616.079 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Immunology
Posttranslational modification Medical microbiology Cancer research Posttranslational Modification Medical Microbiology Cancer Research |
| ISBN | 94-024-1170-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Metabolism in Immune Cell Differentiation and Function -- Metabolic Regulation of T cell Immunity -- Transcriptional regulation of T cell metabolism reprograming -- Adipose tissue-resident regulatory T cells -- Immune cell metabolism in tumor microenvironment -- Regulation of Metabolism across Different Subsets of T Cells in Cancer -- Immunometabolism in Tumour Microenvironment . |
| Record Nr. | UNINA-9910253938603321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Lipid Hydroperoxide-Derived Modification of Biomolecules / / edited by Yoji Kato
| Lipid Hydroperoxide-Derived Modification of Biomolecules / / edited by Yoji Kato |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (203 p.) |
| Disciplina | 572.57 |
| Collana | Subcellular Biochemistry |
| Soggetto topico |
Cancer research
Posttranslational modification Food—Biotechnology Cancer Research Posttranslational Modification Food Science |
| ISBN | 94-007-7920-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface. I Lipid peroxidation and small molecule adducts -- Lipid hydroperoxides as a source of singlet molecular oxygen -- The formation of lipid hydroperoxide-derived amide-type lysine adducts on proteins: a review of current knowledge -- Lipid hydroperoxide-derived adduction to amino-phospholipid in biomembrane -- Amide-type adduct of dopamine - Plausible cause of Parkinson diseases -- Determination of HEL (hexanoyl-lysine adduct): a novel biomarker for omega-6 PUFA oxidation -- Hexanoyl-lysine as a deterioration marker for rice during storage -- Cholesterol hydroperoxides and their degradation mechanism. II Pathophysiological consequences -- Amide-adducts in atherosclerosis -- Oxidative Modification of Lipoproteins -- Immunochemical Detection of Lipid Hydroperoxide- and Aldehyde-Modified Proteins in Diseases -- Role of Lipid Peroxide in the Neurodegenerative Disorders -- Lipid Hydroperoxide-Derived Modification of Proteins in Gastrointestinal Tract. III Applications for diagnosis and development of functional food -- Low-cost and easy-to-use "on-chip ELISA" for developing health-promoting foods -- Hexanoyl-lysine as an oxidative-injured marker - application of development of functional food -- Potential role of oxidative protein modification in energy metabolism in exercise -- Suppressive effects of cacao polyphenols on the development of atherosclerosis in apolipoprotein E-deficient mice -- Index. |
| Record Nr. | UNINA-9910298306103321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Non-coding RNAs and Cancer / / edited by Muller Fabbri
| Non-coding RNAs and Cancer / / edited by Muller Fabbri |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (287 p.) |
| Disciplina |
571.6
572 572.6 599935 |
| Soggetto topico |
Cancer research
Cell biology Biochemistry Posttranslational modification Gene expression Human genetics Cancer Research Cell Biology Biochemistry, general Posttranslational Modification Gene Expression Human Genetics |
| ISBN | 1-4614-8444-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Biogenesis and Physiology of microRNAs.-Detecting non-coding RNA expression: from arrays to next generation sequencing -- MicroRNAs in Solid Tumors.-MicroRNAs in hematologic malignancies -- miRNAs as Cancer Biomarkers -- Unraveling the complex network of interactions between non-coding RNAs and epigenetics in cancer -- MicroRNA SNPs in Cancer -- Bioinformatics Approaches to the study of microRNAs -- Beyond miRNAs: role of other non-coding RNAs in cancer -- Translational Implications for non-coding RNA in Cancer -- Index. |
| Record Nr. | UNINA-9910298337703321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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PlantOmics: The Omics of Plant Science [[electronic resource] /] / edited by Debmalya Barh, Muhammad Sarwar Khan, Eric Davies
| PlantOmics: The Omics of Plant Science [[electronic resource] /] / edited by Debmalya Barh, Muhammad Sarwar Khan, Eric Davies |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | New Delhi : , : Springer India : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (839 p.) |
| Disciplina |
570
572.6 580 660.6 |
| Soggetto topico |
Plant science
Botany Biotechnology Posttranslational modification Proteins Plant Sciences Posttranslational Modification Protein Science |
| ISBN | 81-322-2172-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter-1: Omics of Model Plants -- Chapter-2:Instrumental techniques and methods: their role in plant omics -- Chapter-3:Next generation sequencing and assembly of plant genomes -- Chapter-4: Functional genomics: applications in plant science -- Chapter-5: Cytogenomics and mutagenomics in plant functional biology and breeding -- Chapter-6: Plant Epigenetics and Crop Improvement -- Chapter-7: Plant miRNomics: novel insights in gene expression and regulation -- Chapter-8:Plant Proteomics: Technologies and applications -- Chapter-9: Plant Metabolomics: An overview of technology platforms for applications in metabolism -- Chapter-10:Plant Glycomics: advances and applications -- Chapter-11: Plant Lipidomics: Signalling and Analytical Strategies -- Chapter-12: Plant secretomics: unique initiatives -- Chapter-13: Phenomics: Technologies and applications in plant and agriculture -- Chapter-14: Plant Cytomics: Novel Methods to View Molecules on the Move -- Chapter-15:Plant Physiomics: Photo-electro-chemical and molecular retrograde signaling in plant acclimatory and defence responses -- Chapter-16: Signalomics: diversity and methods of analysis of systemic signals in plants -- Chapter-17: Signalome in salt stress -- Chapter-18: Thiolomics: Molecular mechanisms of thiol-cascade in plant growth and nutrition -- Chapter-19: Chloroplast Omics: global strategies for study of plastid biology -- Chapter-20: Transplastomics: A convergence of genomics and biotechnology -- Chapter-21:Plant Mitochondrial Omics: state of the art knowledge -- Chapter-22: Micromorphomics: a morphological dissection to unveil environmental stress -- Chapter-23: Microbiomics: An approach to community microbiology -- Chapter-24: Cryobionomics: evaluating the concept in plant cryopreservation -- Chapter-25: Nanobiotechnology: applications in plant and agriculture -- Chapter-26: Plant pharmacogenomics: from drug discovery to personalized ethnomedicine -- Chapter-27: Machine learning approaches in plant biology -- Chapter-28: Applications of bioinformatics in plant and agriculture -- Chapter-29: Plant system biology: insights and advancements -- Chapter-30: Plantomics and Futuromics. |
| Record Nr. | UNINA-9910298286103321 |
| New Delhi : , : Springer India : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Protein Tyrosine Phosphatases in Cancer / / edited by Benjamin G. Neel, Nicholas K. Tonks
| Protein Tyrosine Phosphatases in Cancer / / edited by Benjamin G. Neel, Nicholas K. Tonks |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (VIII, 360 p. 28 illus., 19 illus. in color.) |
| Disciplina | 614.5999 |
| Soggetto topico |
Cancer research
Cell biology Posttranslational modification Cancer Research Cell Biology Posttranslational Modification |
| ISBN | 1-4939-3649-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1 Introduction to the PTP Superfamily -- 2 Receptor PTPs in Cancer -- 3 Non-Receptor PTPs in Cancer -- 4 HP2 -- 5 C-PTP -- 6 PTP1B -- 7 PTP-PEST -- 8 Dual Specificity Phosphatases in Cancer -- 9 Phosphatase-dependent roles for PTEN in Cancer -- 10 Phosphatase-independent roles for PTEN in Cancer -- 11 PRL family members in Cancer -- 12 Cdc25 family -- 13 PTPs, metabolism and cancer -- 14 PTPs, metabolism and cancer -- 15 Current status of PTP-based therapeutics -- 16 Summary and Perspective. . |
| Record Nr. | UNINA-9910253894803321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Regulation of Inflammatory Signaling in Health and Disease / / edited by Dakang Xu
| Regulation of Inflammatory Signaling in Health and Disease / / edited by Dakang Xu |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XII, 244 p. 19 illus., 18 illus. in color.) |
| Disciplina | 616.079 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Immunology
Cell biology Posttranslational modification Molecular biology Cell Biology Posttranslational Modification Molecular Medicine |
| ISBN | 981-10-5987-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910253937003321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Study on the Cellular Regulation and Function of Lysine Malonylation, Glutarylation and Crotonylation / / by Xiucong Bao
| Study on the Cellular Regulation and Function of Lysine Malonylation, Glutarylation and Crotonylation / / by Xiucong Bao |
| Autore | Bao Xiucong |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (XVIII, 163 p. 132 illus., 96 illus. in color.) |
| Disciplina | 612.39 |
| Collana | Springer Theses, Recognizing Outstanding Ph.D. Research |
| Soggetto topico |
Bioorganic chemistry
Posttranslational modification Proteins Proteomics Gene expression Cell cycle Bioorganic Chemistry Posttranslational Modification Protein Structure Gene Expression Cell Cycle Analysis |
| ISBN | 981-15-2509-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction to Protein Posttranslational Modifications (PTMs) -- Chemical reporter for Lysine Malonylation -- Identification of Histone Lysine Glutarylation -- Glutarylation at Histone H4 lysine 91 Modulates Chromatin Assembly -- Identification of Sirt3 as an ‘Eraser’ for Histone Lysine Crotonylation Marks using a Chemical Proteomics Approach. |
| Record Nr. | UNINA-9910410051803321 |
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Bao Xiucong
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| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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SUMO Regulation of Cellular Processes / / edited by Van G. Wilson
| SUMO Regulation of Cellular Processes / / edited by Van G. Wilson |
| Edizione | [2nd ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (VIII, 415 p. 41 illus., 26 illus. in color.) |
| Disciplina | 610 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Medicine
Proteins Cell biology Posttranslational modification Biomedicine, general Protein Science Cell Biology Posttranslational Modification |
| ISBN | 3-319-50044-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Introduction to Sumoylation -- Part I Molecular Functions -- Roles of Sumoylation in mRNA Processing and Metabolsim -- SUMO and Chromatin Remodeling -- Functions of SUMO in the Maintenance of Genome Stability -- Regulation of Cellular Processes by SUMO: Understudied Topics -- The Molecular Interface Between The SUMO And Ubiquitin Systems -- . SUMO and Nucleocytoplasmic Transport -- SUMO Modification of Ion Channels -- The Roles of SUMO in Metabolic Regulation -- Part II Cell Growth Regulation -- The SUMO Pathway in Mitosis -- Wrestling with Chromosomes: The Roles of SUMO During Meiosis -- Sumoylation in Development and Differentiation -- The Role of Sumoylation in Senescence -- Regulation of Plant Cellular and Organismal Development by SUMO -- SUMO in Drosophila Development -- Part III Diseases -- SUMOylation: Implications for Neurodegenerative Diseases -- Sumoylation and Its Contribution to Cancer -- Sumoylation Modulates the Susceptibility to Type 1 Diabetes -- Sumoylation in Craniofacial Disorders -- Coordination of Cellular Localization-Dependent Effects of Sumoylation in Regulating Cardiovascular and Neurological Diseases -- Viral Interplay with the Host Sumoylation System -- SUMOylation as an Integral Mechanism in Bacterial Infection and Disease Pathogenesis -- Index. |
| Record Nr. | UNINA-9910165154403321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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