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Analysis of protein post-translational modifications using mass spectrometry / / edited by John R. Griffiths, Richard D. Unwin
| Analysis of protein post-translational modifications using mass spectrometry / / edited by John R. Griffiths, Richard D. Unwin |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley, , 2017 |
| Descrizione fisica | 1 online resource (414 p.) |
| Disciplina | 572/.645 |
| Collana | Wiley Series on Mass Spectrometry |
| Soggetto topico |
Post-translational modification
Mass spectrometry |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-119-25089-7
1-119-25088-9 1-119-25090-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 4.1.4 Mass Spectrometry Analysis |
| Record Nr. | UNINA-9910135027603321 |
| Hoboken, New Jersey : , : Wiley, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Analysis of protein post-translational modifications using mass spectrometry / / edited by John R. Griffiths, Richard D. Unwin
| Analysis of protein post-translational modifications using mass spectrometry / / edited by John R. Griffiths, Richard D. Unwin |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley, , 2017 |
| Descrizione fisica | 1 online resource (414 p.) |
| Disciplina | 572/.645 |
| Collana | Wiley Series on Mass Spectrometry |
| Soggetto topico |
Post-translational modification
Mass spectrometry |
| ISBN |
1-119-25089-7
1-119-25088-9 1-119-25090-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 4.1.4 Mass Spectrometry Analysis |
| Record Nr. | UNINA-9910830389803321 |
| Hoboken, New Jersey : , : Wiley, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Biology of mRNA: Structure and Function / / edited by Marlene Oeffinger, Daniel Zenklusen
| The Biology of mRNA: Structure and Function / / edited by Marlene Oeffinger, Daniel Zenklusen |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (318 pages) |
| Disciplina | 572.88 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Medicine—Research
Biology—Research Molecular genetics Proteins Neurosciences Post-translational modification Biomedical Research Molecular Genetics Protein Biochemistry Neuroscience Post-translational Modifications RNA |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-31434-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Regulation of co-transcriptional mRNP assembly -- mRNA export through the NPC -- Roles of mRNA modifications in gene regulation -- Studying mRNPs using single molecule approaches -- Difference between mRNPs and lncRNAs? -- RNPs and/or sequence motives in mRNA localization -- mRNP structure -- New RNA binding proteins: mRNP composition -- Aggregation of repeats RNAs in neurodegenerative diseases -- mRNA structural organization and translation -- How to decide to make an mRNA - degradation -- Methods to study mRNP composition -- mRNA-DNA kisses – R-loops -- Forms of mRNA editing and their role in disease. |
| Record Nr. | UNINA-9910373908303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Cullin-RING Ligases and Protein Neddylation : Biology and Therapeutics / / edited by Yi Sun, Wenyi Wei, Jianping Jin
| Cullin-RING Ligases and Protein Neddylation : Biology and Therapeutics / / edited by Yi Sun, Wenyi Wei, Jianping Jin |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (VIII, 372 p. 119 illus., 68 illus. in color.) |
| Disciplina | 572.8 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Medicine - Research
Biology - Research Post-translational modification Cytology Biomedical Research Post-translational Modifications Cell Biology |
| ISBN | 981-15-1025-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1 Introduction of Protein Ubiquitination and Cullin/RING Ubiquitin Ligases: introduce the protein ubiquitination system briefly; discuss the family of Cullin/RING Ubiquitin Ligases -- Chapter 2 Assembly and Regulation of CRL ubiquitin ligases: discuss the assembly process of CRL ubiquitin ligases by CAND1; elaborate the regulation of CRL ubiquitin ligases by neddylation -- Chapter 3 Protein structure of CRL and Neddylation complex -- Chapter 4 The roles of CRL ubiquitin ligases and neddylation in human diseases -- Chapter 5 The roles of CRL ubiquitin ligases in stem cell biology: Briefly introduce concept and potential application of stem cells; analyze a few example for CRL ubiquitin ligases to control stem cell biology -- Chapter 6 The biology of F-box proteins: introduce the history of SCF ubiquitin ligases; discuss the overall functions of F-box proteins (emphasize phospho-degron concept) -- Chapter 7 The roles of Fbxw7 in human diseases: discuss the roles of Fbw7 in cancer; elaborate the roles of Fbxw7 in other diseases -- Chapter 8 Mouse models of CRL1 components to study their biological function -- Chapter 9 Cullin2 and cancer: introduce Cullin2 ubiquitin ligases; discuss VHL ubiquitin ligase and its roles in cancer -- Chapter 10 Cullin3 and tumorigenesis: introduce Cullin3 ubiquitin ligases; discuss a few examples of Cullin3 ubiquitin ligases in control of tumorigenesis -- Chapter 11 Cullin4-DCAF proteins in tumorigenesis: Discovery of DCAF proteins; discuss a few examples of DCAF’s biological functions -- Chapter 12 Cullin4 ubiquitin ligases in DNA damage responses: Introduce Cullin4 ubiquitin ligases; discuss the roles of Cullin4 ubiquitin ligases in DNA damage responses -- Chapter 13 Coordinating the roles of Cullin5 ubiquitin ligases by SAG and UBE2F: introduce Cullin5 ubiquitin ligases; discuss how SGA and UBE2F mediates the functions of Cullin5 -- Chapter 14 Cullin5 in anti-virus infection: mechanism and drug target -- Chapter 15 The roles of Cul7 in cancerbiology: introduce Cullin7 ubiquitin ligase7; discuss a few examples of Cullin7 ubiquitin ligases in cancer -- Chapter 16 Coordinating functions of p97 and CRL ubiquitin ligases in protein turnover: introduce the interactions between p97 and CRL ubiquitin ligases; discuss the coordinating roles between p97 and CRL ubiquitin ligases in protein turnover -- Chapter 17 Interaction between CRL ubiquitin ligases and COP9 Signalosome: introduce Cop9 signalosome; discuss how Cop9 signalosome regulates CRL ubiquitin ligases -- Chapter 18 Drug discovery effort to target Cullin-3 neddylation: discuss inhibitor of Cullin3 neddylation and its application -- Chapter 19 Targeting neddylation modification: Briefly introduce protein neddylation; discuss the roles of neddylation in cancer -- Chapter 20 Targeting CRL ubiquitin ligases: discuss current progress in targeting CRL ubiquitin ligases; discuss the application of CRL ubiquitin ligases in Protac drug development. |
| Record Nr. | UNINA-9910373936803321 |
| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Epigenetics in Allergy and Autoimmunity / / edited by Christopher Chang, Qianjin Lu
| Epigenetics in Allergy and Autoimmunity / / edited by Christopher Chang, Qianjin Lu |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (408 pages) |
| Disciplina | 572.865 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Immunology
Post-translational modification Rheumatology Allergy Posttranslational Modification Allergology Epigenètica Al·lèrgia Sistema immunitari |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 981-15-3449-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Epigenetics in health and disease -- The development of epigenetics in the study of disease pathogenesis -- Epigenetic methods and twin studies -- The role of genetics, the environment and epigenetics in atopic dermatitis -- The epigenetics of food allergy -- Epigenetics and the Environment in allergy and asthma: asthma and allergic rhinitis -- Epigenetics of lupus erythematosus -- Epigenetics of psoriasis -- The role of epigenetics in type 1 diabetes -- Epigenetics of Primary Biliary Cholangitis -- Epigenetics in primary Sjogren’s syndrome -- Epigenetics in Multiple Sclerosis -- The epigenetic regulation of Scleroderma and its clinical application. |
| Record Nr. | UNINA-9910409692603321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The epigenetics of autoimmune diseases [[electronic resource] /] / edited by Moncef Zouali
| The epigenetics of autoimmune diseases [[electronic resource] /] / edited by Moncef Zouali |
| Pubbl/distr/stampa | Chichester ; ; Hoboken, NJ, : Wiley-Blackwell, 2009 |
| Descrizione fisica | 1 online resource (473 p.) |
| Disciplina |
571.9/73
571.973 616.978042 |
| Altri autori (Persone) | ZoualiMoncef <1952-> |
| Soggetto topico |
Autoimmunity - Molecular aspects
Autoimmune diseases - Etiology Post-translational modification Epigenesis |
| ISBN |
1-282-13817-0
9786612138171 0-470-74355-7 0-470-74356-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Epigenetics of Autoimmune Diseases; Contents; Preface; Contributors; PART I Transcription Factors: Partners of Immune Tolerance to Self; 1 Transcriptional regulation of T cell tolerance; 1.1 Introduction; 1.2 T cell anergy; 1.3 Ca2+/calcineurin/NFAT signalling in T cell anergy; 1.4 Transcriptional programme of T cell anergy; 1.5 Transcriptional repression in T cell anergy: epigenetic modification of the Il2 promoter; 1.6 Regulatory T cells; 1.7 Transcriptional control of Treg development and function; References; 2 Epigenetic regulation of Foxp3 expression in regulatory T cells
2.1 Introduction2.2 Naturally occurring CD25+ CD4+ Tregs; 2.3 The transcription factor FOXP3: determining Treg function and identity; 2.4 Molecular regulation of FOXP3; 2.5 Tregs as a stable lineage: indications of epigenetic imprinting; 2.6 Induced Tregs: stable suppressors or transient immuno-modulators?; 2.7 Conclusions; References; 3 The role of NF-kB in central tolerance; 3.1 Introduction; 3.2 Canonical and alternative NF-kB pathways; 3.3 Thymic stroma and central tolerance; 3.4 NF-kB and regulatory T cell development; 3.5 NF-kB and thymocyte positive and negative selection 3.6 Conclusions and perspectives3.7 Acknowledgement; References; 4 The role of Act1 in the control of autoimmunity; 4.1 Introduction; 4.2 Autoimmunity and autoimmune mouse models; 4.3 Molecular mechanisms of autoimmunity; 4.4 Act1: a modulator of autoimmunity; 4.5 Conclusions; References; 5 Regulation of T cell anergy and escape from regulatory T cell suppression by Cbl-b; 5.1 Introduction; 5.2 Mechanisms of T cell tolerance induction; 5.3 Molecular establishment of T cell anergy; 5.4 Ubiquitin E3 ligases in T cell tolerance; 5.5 Molecular function and regulation of Cbl-b 5.6 Physiological relevance of Cbl-b5.7 The role of Cbl-b in T cell tolerance; 5.8 Deregulation of Cbl-b in disease; 5.9 Therapeutic potential of Cbl-b in tumour immunity; 5.10 Implications for autoimmune disease; References; 6 Indoleamine 2,3-dioxygenase: transcriptional regulation and autoimmunity; 6.1 Introduction; 6.2 L-Trp degradation along the kynurenine pathway and immune functions of IDO; 6.3 IDO immunobiology and therapeutic intervention; 6.4 Transcriptional regulation of the IDO-encoding gene; 6.5 Impaired IDO activity and loss of tolerance in autoimmune diseases 6.6 IDO-based therapies for autoimmune disease6.7 Acknowledgement; References; PART II Stress Responses that Break Immune Silence; 7 Chromatin modifications, oxidative stress and nucleosome autoantibodies; 7.1 Introduction; 7.2 Nucleosome and SLE; 7.3 Epigenetics and SLE; 7.4 Oxidative stress in SLE: definition and mechanisms; 7.5 Oxidative stress, epigenetic alterations and nucleosome immunogenicity; 7.6 Conclusion; 7.7 Acknowledgements; References; 8 Stress, epigenetics and thyroid autoimmunity; 8.1 Introduction; 8.2 The Th1/Th2 balance in immune-response regulation 8.3 Stress hormones and the Th1/Th2 balance |
| Record Nr. | UNINA-9910146133703321 |
| Chichester ; ; Hoboken, NJ, : Wiley-Blackwell, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The epigenetics of autoimmune diseases [[electronic resource] /] / edited by Moncef Zouali
| The epigenetics of autoimmune diseases [[electronic resource] /] / edited by Moncef Zouali |
| Pubbl/distr/stampa | Chichester ; ; Hoboken, NJ, : Wiley-Blackwell, 2009 |
| Descrizione fisica | 1 online resource (473 p.) |
| Disciplina |
571.9/73
571.973 616.978042 |
| Altri autori (Persone) | ZoualiMoncef <1952-> |
| Soggetto topico |
Autoimmunity - Molecular aspects
Autoimmune diseases - Etiology Post-translational modification Epigenesis |
| ISBN |
1-282-13817-0
9786612138171 0-470-74355-7 0-470-74356-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Epigenetics of Autoimmune Diseases; Contents; Preface; Contributors; PART I Transcription Factors: Partners of Immune Tolerance to Self; 1 Transcriptional regulation of T cell tolerance; 1.1 Introduction; 1.2 T cell anergy; 1.3 Ca2+/calcineurin/NFAT signalling in T cell anergy; 1.4 Transcriptional programme of T cell anergy; 1.5 Transcriptional repression in T cell anergy: epigenetic modification of the Il2 promoter; 1.6 Regulatory T cells; 1.7 Transcriptional control of Treg development and function; References; 2 Epigenetic regulation of Foxp3 expression in regulatory T cells
2.1 Introduction2.2 Naturally occurring CD25+ CD4+ Tregs; 2.3 The transcription factor FOXP3: determining Treg function and identity; 2.4 Molecular regulation of FOXP3; 2.5 Tregs as a stable lineage: indications of epigenetic imprinting; 2.6 Induced Tregs: stable suppressors or transient immuno-modulators?; 2.7 Conclusions; References; 3 The role of NF-kB in central tolerance; 3.1 Introduction; 3.2 Canonical and alternative NF-kB pathways; 3.3 Thymic stroma and central tolerance; 3.4 NF-kB and regulatory T cell development; 3.5 NF-kB and thymocyte positive and negative selection 3.6 Conclusions and perspectives3.7 Acknowledgement; References; 4 The role of Act1 in the control of autoimmunity; 4.1 Introduction; 4.2 Autoimmunity and autoimmune mouse models; 4.3 Molecular mechanisms of autoimmunity; 4.4 Act1: a modulator of autoimmunity; 4.5 Conclusions; References; 5 Regulation of T cell anergy and escape from regulatory T cell suppression by Cbl-b; 5.1 Introduction; 5.2 Mechanisms of T cell tolerance induction; 5.3 Molecular establishment of T cell anergy; 5.4 Ubiquitin E3 ligases in T cell tolerance; 5.5 Molecular function and regulation of Cbl-b 5.6 Physiological relevance of Cbl-b5.7 The role of Cbl-b in T cell tolerance; 5.8 Deregulation of Cbl-b in disease; 5.9 Therapeutic potential of Cbl-b in tumour immunity; 5.10 Implications for autoimmune disease; References; 6 Indoleamine 2,3-dioxygenase: transcriptional regulation and autoimmunity; 6.1 Introduction; 6.2 L-Trp degradation along the kynurenine pathway and immune functions of IDO; 6.3 IDO immunobiology and therapeutic intervention; 6.4 Transcriptional regulation of the IDO-encoding gene; 6.5 Impaired IDO activity and loss of tolerance in autoimmune diseases 6.6 IDO-based therapies for autoimmune disease6.7 Acknowledgement; References; PART II Stress Responses that Break Immune Silence; 7 Chromatin modifications, oxidative stress and nucleosome autoantibodies; 7.1 Introduction; 7.2 Nucleosome and SLE; 7.3 Epigenetics and SLE; 7.4 Oxidative stress in SLE: definition and mechanisms; 7.5 Oxidative stress, epigenetic alterations and nucleosome immunogenicity; 7.6 Conclusion; 7.7 Acknowledgements; References; 8 Stress, epigenetics and thyroid autoimmunity; 8.1 Introduction; 8.2 The Th1/Th2 balance in immune-response regulation 8.3 Stress hormones and the Th1/Th2 balance |
| Record Nr. | UNINA-9910830763503321 |
| Chichester ; ; Hoboken, NJ, : Wiley-Blackwell, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The epigenetics of autoimmune diseases / / edited by Moncef Zouali
| The epigenetics of autoimmune diseases / / edited by Moncef Zouali |
| Pubbl/distr/stampa | Chichester ; ; Hoboken, NJ, : Wiley-Blackwell, 2009 |
| Descrizione fisica | 1 online resource (473 p.) |
| Disciplina | 571.9/73 |
| Altri autori (Persone) | ZoualiMoncef <1952-> |
| Soggetto topico |
Autoimmunity - Molecular aspects
Autoimmune diseases - Etiology Post-translational modification Epigenesis |
| ISBN |
9786612138171
9781282138179 1282138170 9780470743553 0470743557 9780470743560 0470743565 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Epigenetics of Autoimmune Diseases; Contents; Preface; Contributors; PART I Transcription Factors: Partners of Immune Tolerance to Self; 1 Transcriptional regulation of T cell tolerance; 1.1 Introduction; 1.2 T cell anergy; 1.3 Ca2+/calcineurin/NFAT signalling in T cell anergy; 1.4 Transcriptional programme of T cell anergy; 1.5 Transcriptional repression in T cell anergy: epigenetic modification of the Il2 promoter; 1.6 Regulatory T cells; 1.7 Transcriptional control of Treg development and function; References; 2 Epigenetic regulation of Foxp3 expression in regulatory T cells
2.1 Introduction2.2 Naturally occurring CD25+ CD4+ Tregs; 2.3 The transcription factor FOXP3: determining Treg function and identity; 2.4 Molecular regulation of FOXP3; 2.5 Tregs as a stable lineage: indications of epigenetic imprinting; 2.6 Induced Tregs: stable suppressors or transient immuno-modulators?; 2.7 Conclusions; References; 3 The role of NF-kB in central tolerance; 3.1 Introduction; 3.2 Canonical and alternative NF-kB pathways; 3.3 Thymic stroma and central tolerance; 3.4 NF-kB and regulatory T cell development; 3.5 NF-kB and thymocyte positive and negative selection 3.6 Conclusions and perspectives3.7 Acknowledgement; References; 4 The role of Act1 in the control of autoimmunity; 4.1 Introduction; 4.2 Autoimmunity and autoimmune mouse models; 4.3 Molecular mechanisms of autoimmunity; 4.4 Act1: a modulator of autoimmunity; 4.5 Conclusions; References; 5 Regulation of T cell anergy and escape from regulatory T cell suppression by Cbl-b; 5.1 Introduction; 5.2 Mechanisms of T cell tolerance induction; 5.3 Molecular establishment of T cell anergy; 5.4 Ubiquitin E3 ligases in T cell tolerance; 5.5 Molecular function and regulation of Cbl-b 5.6 Physiological relevance of Cbl-b5.7 The role of Cbl-b in T cell tolerance; 5.8 Deregulation of Cbl-b in disease; 5.9 Therapeutic potential of Cbl-b in tumour immunity; 5.10 Implications for autoimmune disease; References; 6 Indoleamine 2,3-dioxygenase: transcriptional regulation and autoimmunity; 6.1 Introduction; 6.2 L-Trp degradation along the kynurenine pathway and immune functions of IDO; 6.3 IDO immunobiology and therapeutic intervention; 6.4 Transcriptional regulation of the IDO-encoding gene; 6.5 Impaired IDO activity and loss of tolerance in autoimmune diseases 6.6 IDO-based therapies for autoimmune disease6.7 Acknowledgement; References; PART II Stress Responses that Break Immune Silence; 7 Chromatin modifications, oxidative stress and nucleosome autoantibodies; 7.1 Introduction; 7.2 Nucleosome and SLE; 7.3 Epigenetics and SLE; 7.4 Oxidative stress in SLE: definition and mechanisms; 7.5 Oxidative stress, epigenetic alterations and nucleosome immunogenicity; 7.6 Conclusion; 7.7 Acknowledgements; References; 8 Stress, epigenetics and thyroid autoimmunity; 8.1 Introduction; 8.2 The Th1/Th2 balance in immune-response regulation 8.3 Stress hormones and the Th1/Th2 balance |
| Record Nr. | UNINA-9911020016503321 |
| Chichester ; ; Hoboken, NJ, : Wiley-Blackwell, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Epigenetics: Development and Disease / / edited by Tapas Kumar Kundu
| Epigenetics: Development and Disease / / edited by Tapas Kumar Kundu |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (697 p.) |
| Disciplina |
572.865
616.042 |
| Altri autori (Persone) | KunduTapas K |
| Collana | Subcellular Biochemistry |
| Soggetto topico |
Molecular genetics
Post-translational modification Cancer Developmental biology Stem cells Molecular Genetics Post-translational Modifications Cancer Biology Developmental Biology and Stem Cells Stem Cell Biology |
| ISBN |
1-283-84976-3
94-007-4525-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | PART I: EPIGENETICS AND EVOLUTION -- 1.1 Chromatin Organization, Epigenetics and Differentiation: An evolutionary perspective -- 1.2 Secondary structures of the core histone N-terminal tails: their role in regulating chromatin structure -- 1.3 Megabase replication domains along the human genome: Relation to chromatin structure and genome organization -- 1.4 Role of DNA methyltransferases in epigenetic regulation in bacteria -- PART II: DEVELOPMENTAL EPIGENETICS -- 2.1 Metabolic aspects of epigenome: Coupling of S-adenosylmethionine synthesis and gene regulation on chromatin by SAMIT module -- 2.2 Epigenetic regulation of male germ cell differentiation -- 2.3 Epigenetic Regulation of Skeletal Muscle Development and Differentiation -- 2.4 Small changes, big effects: chromatin goes aging -- 2.5 Homeotic gene regulation: A paradigm for epigenetic mechanisms underlying organismal development -- PART III: EPIGENETICS AND TRANSCRIPTION REGULATION -- 3.1 Basic mechanisms in RNA Polymerase I transcriptionof the ribosomal RNA genes -- 3.2 The RNA polymerase II transcriptional machinery and its epigenetic context -- 3.3 RNA polymerase III transcriptions - regulated by chromatin structure and regulator of nuclear chromatin organization -- 3.4. The Role of DNA Methylation and Histone Modifications in Transcriptional Regulation in humans -- 3.5 Histone variants and Transcription regulation -- 3.6 Noncoding RNAs in Chromatin Organization and Transcription Regulation: An Epigenetic View -- 3.7 Chromatin structure and organization: the relation with gene expression during development and disease -- PART IV: EPIGENETICS AND DISEASE -- 4.1 Epigenetics and cancer: Development, Differentiation and Pathobiology -- 4.2 Epigenetic Regulation of Cancer Stem Cell Gene Expression -- 4.3 Role of Epigenetic Mechanisms in the Vascular Complications of Diabetes -- 4.4 Epigenetic changes in inflammatory and autoimmune diseases -- 4.5 Epigenetic regulation of HIV-1 persistence and evolving strategies for virus eradication -- 4.6 Epigenetics in Parkinson’s and Alzheimer’s diseases -- 4.7 Cellular Redox, Epigenetics and Diseases -- PART V: UNDERSTANDING OF EPIGENETICS: A CHEMICAL BIOLOGY APPROACH AND EPIGENETIC THERAPY -- 5.1 Stem cell plasticity in development and cancer: Epigenetic origin of cancer stem cells -- 5.2 Histone acetylation as a therapeutic target- Implication of nanodelivery -- 5.3 DNA methylation and Cancer -- 5.4 Role of epigenetics in inflammation-associated diseases -- 5.5 Plasmodium falciparum: Epigenetic control of var gene regulation and disease. |
| Record Nr. | UNINA-9910437829103321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Global strategies for disease detection and treatment [[electronic resource] ] : proteomics / / guest editor Sam Hanash ; foreword by Sudhir Srivastava and Sam Hanash
| Global strategies for disease detection and treatment [[electronic resource] ] : proteomics / / guest editor Sam Hanash ; foreword by Sudhir Srivastava and Sam Hanash |
| Pubbl/distr/stampa | Amsterdam, : International Organisations Services, 2001 |
| Descrizione fisica | 1 online resource (115 p.) |
| Disciplina | 572.6 |
| Altri autori (Persone) |
SrivastavaSudhir <1954->
HanashSamir M |
| Collana | Disease markers |
| Soggetto topico |
Proteomics
Proteins - Structure Protein binding Gene expression DNA microarrays Post-translational modification |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-50548-6
9786610505487 600-00-0441-9 1-60129-430-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Foreword: Global Strategies for Disease Detection and Treatment: Proteomics; Proteome analysis - A novel approach to understand the pathogenesis of Type 1 diabetes mellitus; Proteomic-based approach for the identification of tumor markers associated with hepatocellular carcinoma; The application of protein microarrays to serum diagnostics: Prostate cancer as a test case; Protein expression analysis: From 'tip of the iceberg' to a global method; Analysis of the proteomic profiling of brain tissue in Alzheimer's disease; Proteomics and the inner ear
Proteomics as the tool to search for lung disease markers in bronchoalveolar lavagePseudomonas aeruginosa and a proteomic approach to bacterial pathogenesis; A proteomic approach to the identification of lung cancer markers; Proteomic patterns of nipple aspirate fluids obtained by SELDI-TOF: Potential for new biomarkers to aid in the diagnosis of breast cancer; Author Index Volume 17 (2001); Keyword Index Volume 17 (2001) |
| Record Nr. | UNINA-9910455941703321 |
| Amsterdam, : International Organisations Services, 2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
