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Practical Guide to Hereditary Breast and Ovarian Cancer : Annual Meeting of the Japanese Organization of Hereditary Breast and Ovarian Cancer 2021 / / edited by Daisuke Aoki, Seigo Nakamura, Yoshio Miki
| Practical Guide to Hereditary Breast and Ovarian Cancer : Annual Meeting of the Japanese Organization of Hereditary Breast and Ovarian Cancer 2021 / / edited by Daisuke Aoki, Seigo Nakamura, Yoshio Miki |
| Autore | Aoki Daisuke |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (147 pages) |
| Disciplina | 616.99449 |
| Altri autori (Persone) |
NakamuraSeigo
MikiYoshio |
| Soggetto topico |
Oncology
Endoscopic surgery Surgery Cancer - Genetic aspects Medicine - Research Biology - Research Breast Neoplasms - genetics Ovarian Neoplasms - genetics Poly(ADP-ribose) Polymerase Inhibitors Biomedical Research Minimally Invasive Surgery Cancer Genetics and Genomics |
| ISBN | 981-9952-31-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I Breast -- 1 Establishment of a medical system with HBOC in mind -- 2 Guidelines for diagnosis and treatment of HBOC: Methods and Products -- 3 RRM from a Plastic Surgery Perspective -- Part 2 Gynecology -- 4 Significance of p53 signature in RRSO samples -- 5 Mutual feedback between gynecological HBOC practice and cancer genomic medicine -- Part 3 Basic Science -- 6 Diversity of HBOC-Related Genes Revealed by Genome Analysis -- 7 New functions of BRCA1/2 regulating carcinogenesis and drug sensitivity -- Part 4 Health and Labor Sciences Research Grant -- 8 Systemic Issues in HBOC Treatment -- 9 Current status and future issues of the activities of the relevant organizations -- Part 5 Congress Award -- 10 Understanding the significance of the test in relatives of prostate and pancreatic cancer patients who tested positive on BRACAnalysis -- 11 Handling Germline Findings in Ovarian Cancer Cases -- Part 6 JOHBOC registration -- 12 JOHBOC registration data up to date 2021. |
| Record Nr. | UNINA-9910760287003321 |
Aoki Daisuke
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| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting the DNA Damage Response for Cancer Therapy / / edited by Timothy A. Yap, Geoffrey I. Shapiro
| Targeting the DNA Damage Response for Cancer Therapy / / edited by Timothy A. Yap, Geoffrey I. Shapiro |
| Autore | Yap Timothy A |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (333 pages) |
| Disciplina | 616.99406 |
| Altri autori (Persone) | ShapiroGeoffrey I |
| Collana | Cancer Treatment and Research |
| Soggetto topico |
Oncology
Medical radiology Pharmacology DNA Repair Neoplasms - therapy Poly(ADP-ribose) Polymerase Inhibitors DNA Repair Enzymes Radiation Oncology |
| ISBN | 3-031-30065-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Evolution of the development of PARP inhibitors -- Exploiting cancer synthetic lethality in cancer – Lessons learnt from PARP inhibitors -- Mechanisms of PARP inhibitor resistance -- Development of homologous recombination functional assays for targeting the DDR -- Clinical application of Poly(ADP Ribose) Polymerase (PARP) inhibitors in ovarian cancer -- Clinical use of PARP inhibitors in BRCA mutant and non-BRCA mutant breast cancer -- Development of PARP inhibitors in targeting castration-resistant prostate cancer -- Strategies for the management of patients with pancreatic cancer with PARP inhibitors -- Combining poly (ADP-ribose) polymerase (PARP) inhibitors with chemotherapeutic agents: Promise and challenges -- Rational combinations of PARP inhibitors with HRD-inducing molecularly targeted agents -- Combining PARP inhibition and immunotherapy in BRCA-associated cancers -- Mitotic MTH1 inhibitors in treatment of cancer -- Targeting ATR in cancer medicine -- Targeting polymerase Theta (POLq) for cancer therapy -- Targeting DNA-PK -- WRN is a promising synthetic lethal target for cancers with microsatellite instability (MSI). |
| Record Nr. | UNINA-9910765480003321 |
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Yap Timothy A
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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