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The 3-Dimensional Atlas of the Marmoset Brain : Reconstructible in Stereotaxic Coordinates / / edited by Atsushi Iriki, Hirotaka James Okano, Erika Sasaki, Hideyuki Okano
The 3-Dimensional Atlas of the Marmoset Brain : Reconstructible in Stereotaxic Coordinates / / edited by Atsushi Iriki, Hirotaka James Okano, Erika Sasaki, Hideyuki Okano
Edizione [1st ed. 2018.]
Pubbl/distr/stampa Tokyo : , : Springer Japan : , : Imprint : Springer, , 2018
Descrizione fisica 1 online resource (396 pages)
Disciplina 611.81
Collana Brain Science
Soggetto topico Neurosciences
Human physiology
Animal anatomy
Pharmacology
Behavioral sciences
Human Physiology
Animal Anatomy / Morphology / Histology
Pharmacology/Toxicology
Behavioral Sciences
ISBN 4-431-56612-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Editors -- Contributors -- Acknowledgement -- Chapter 1 -- Introduction -- Materials and Methods -- Histology -- MRI -- Nomenclature -- List of Brain Structures in Hierarchical Order -- Index of Abbreviations -- Bibliographic References -- Chapter 2 -- Horizontal Series of Images with Neurosurgical Plane (based on the actual data) -- Chapter 3 -- Coronal Series of Images with Neurosurgical Plane (reproduced from the brain model) -- Chapter 4 -- Parasagittal Series of Images with Neurosurgical Plane (reproduced from the brain model) -- Chapter 5 -- Omnidirectionally Sliceable Planes (reproduced from the brain model) -- A. Modified Horizontal Slices -- B. Modified Coronal Slices -- C. Modified Parasagittal Slices -- Index.
Record Nr. UNINA-9910303441203321
Tokyo : , : Springer Japan : , : Imprint : Springer, , 2018
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70 Years of Levothyroxine / / edited by George J. Kahaly
70 Years of Levothyroxine / / edited by George J. Kahaly
Autore Kahaly George J
Edizione [1st ed. 2021.]
Pubbl/distr/stampa Springer Nature, 2021
Descrizione fisica 1 online resource (XVII, 129 p. 37 illus., 34 illus. in color.)
Disciplina 616.4
615.36
Soggetto topico Endocrinology 
Pharmacology
Endocrinology
Pharmacology/Toxicology
Hormones tiroides
Medicaments
Farmacologia
Malalties de les glàndules endocrines
Soggetto genere / forma Llibres electrònics
Soggetto non controllato Endocrinology
Pharmacology/Toxicology
Pharmacology
Thyroid gland
Hypothyroidism
TSH
Thyroid disorders
Metabolism
Open Access
ISBN 3-030-63277-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto History Of Levothyroxine -- Pharmacokinetics Of Levothyroxine -- Pharmacodynamics Of Levothyroxine -- Levothyroxine In Pregnancy -- Levothyroxine In Children -- Levothyroxine In The Elderly -- Levothyroxine And Heart -- Levothyroxine And Bone -- Levothyroxine And Cancer -- Potential Adverse Reactions Of Levothyroxine.
Record Nr. UNINA-9910473450103321
Kahaly George J  
Springer Nature, 2021
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The Actin Cytoskeleton / / edited by Brigitte M. Jockusch
The Actin Cytoskeleton / / edited by Brigitte M. Jockusch
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (XII, 352 p. 60 illus., 30 illus. in color.)
Disciplina 571.654072
Collana Handbook of Experimental Pharmacology
Soggetto topico Pharmacology
Cell physiology
Pharmacology/Toxicology
Cell Physiology
ISBN 3-319-46371-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Functional significance of actin isoforms -- Assembly and maintenance of myofibrils in striated muscle cells -- Myosins: Domain organisation, motor properties, physiological roles and cellular functions -- Actin filament structures in migrating vertebrate cells -- Signalling pathways controlling cellular actin organization -- Actin-based endocytosis -- ADP-ribosylation and cross-linking of actin by bacterial protein toxins -- Common themes in cytoskeletal remodeling by intracellular bacterial effectors -- Viruses that exploit actin-based motility for their replication and spread -- Multiscale view of cytoskeletal mechanoregulation of cell and tissue polarity -- Molecular control of actin dynamics in vivo insights from Drosophila -- From cytoskeleton to gene expression – actin in the nucleus.
Record Nr. UNINA-9910158672603321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
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The Actin Cytoskeleton and Bacterial Infection / / edited by Hans Georg Mannherz
The Actin Cytoskeleton and Bacterial Infection / / edited by Hans Georg Mannherz
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (X, 242 p.)
Disciplina 579.317852
Collana Current Topics in Microbiology and Immunology
Soggetto topico Medical microbiology
Pharmacology
Medical Microbiology
Pharmacology/Toxicology
ISBN 3-319-50047-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Actin structure and dynamics -- Influence of binary actin-depolymerizing toxins on the microtubule system -- ADP-ribosylation of actin by Photorhabdus luminescens TccC3 inhibits interaction with actin binding proteins essential for treadmilling -- Pathogenic mechanisms of actin cross-linking toxins – peeling away the layers -- New concepts on bacterial effectors targeting Rho GTPases -- Interaction of bacterial ADPribosyltransferases with actin -- Yersinia's ways to activate and inactivate actin rearrangements in host cells -- The role of formins in phagocytosis of Borrelia by macrophages.
Record Nr. UNINA-9910163990903321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
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Adherence to Antipsychotics in Schizophrenia / / by Emilio Sacchetti, Antonio Vita, Alberto Siracusano, Wolfgang Fleischhacker
Adherence to Antipsychotics in Schizophrenia / / by Emilio Sacchetti, Antonio Vita, Alberto Siracusano, Wolfgang Fleischhacker
Autore Sacchetti Emilio
Edizione [1st ed. 2014.]
Pubbl/distr/stampa Milano : , : Springer Milan : , : Imprint : Springer, , 2014
Descrizione fisica 1 online resource (168 p.)
Disciplina 615/.7882
616.89806
Soggetto topico Psychiatry
Psychopharmacology
Psychotherapy   
Neurosciences
Pharmacology
Psychotherapy
Pharmacology/Toxicology
ISBN 88-470-2679-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1 Poor adherence to antipsychotic medication in people with schizophrenia: diffusion, consequences, and contributing factors -- Premise -- Role of antipsychotics in the treatment of schizophrenia -- Compliance versus adherence -- Assessment of medication adherence -- Frequency of poor adherence to antipsychotics -- Consequences of poor adherence to antipsychotics -- Determinants and moderators of adherence to antipsychotics -- Present and medium-term perspectives -- Closing Remarks -- 2 Pharmacological strategies to enhance adherence in schizophrenia -- Introduction -- Pharmacological factors contributing to non-adherence: efficacy, side effects, regimen, co-therapies -- First vs Second generation antipsychotics: efficacy, tolerability and the adherence issue -- Long-acting injectable antipsychotics -- Conclusion. 3 Non-pharmacological strategies to enhance adherence and continuity of care in schizophrenia -- Introduction -- Factors Influencing (non-)adherence in Schizophrenia -- Interventions to Enhance Adherence. Research and Clinical Evidence -- Comprehensive Review of Psychosocial and Programmatic Interventions to Enhance Adherence to Antipsychotic Medication in Schizophrenia -- Summary of Main Results and Evidences -- Conclusions and Future Directions -- 4 Psychological issues in improving adherence and alliance -- The patient-doctor relationship as a determinant of adherence to treatment -- Alliance and psychodynamic issues -- Towards the concept of concordance of the therapeutic project.
Record Nr. UNINA-9910300331703321
Sacchetti Emilio  
Milano : , : Springer Milan : , : Imprint : Springer, , 2014
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Adhesion G Protein-coupled Receptors : Molecular, Physiological and Pharmacological Principles in Health and Disease / / edited by Tobias Langenhan, Torsten Schöneberg
Adhesion G Protein-coupled Receptors : Molecular, Physiological and Pharmacological Principles in Health and Disease / / edited by Tobias Langenhan, Torsten Schöneberg
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (XIV, 403 p. 68 illus., 67 illus. in color.)
Disciplina 613
Collana Handbook of Experimental Pharmacology
Soggetto topico Pharmacology
Human physiology
Human genetics
Cell biology
Medical biochemistry
Pharmacology/Toxicology
Human Physiology
Human Genetics
Cell Biology
Medical Biochemistry
ISBN 3-319-41523-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto PART I. Molecular and Pharmacological Properties of Adhesion GPCRs:-Classification, Nomenclature and Structural Aspects of Adhesion GPCRs -- 7TM Domain Structure of Adhesion GPCRs -- Understanding the Structural Basis of Adhesion GPCR Functions.-Control of Adhesion GPCR Function Through Proteolytic Processing.-Tethered Agonism: A Common Activation Mechanism of Adhesion GPCRs -- Versatile Signaling Activity of Adhesion GPCRs -- Adhesion GPCR-Related Protein Networks.-The Relevance of Genomic Signatures at Adhesion GPCR Loci in Humans -- PART II: Adhesion GPCRs as Pharmakotargets in Organ Function and Development -- Adhesion GPCRs as a Putative Class of Metabotropic Mechanosensors -- Adhesion GPCRs Govern Polarity of Epithelia and Cell Migration -- Adhesion GPCRs as Novel Actors in Neural and Glial Cell Functions: From Synaptogenesis to Myelination.-Control of Skeletal Muscle Cell Growth and Size Through Adhesion GPCRs -- Adhesion GPCR Function in Pulmonary Development and Disease.-Adhesion GPCRs as Modulators of Immune Cell Function.-Heart Development, Angiogenesis, and Blood-Brain Barrier Function is Modulated by Adhesion GPCRs.-Adhesion GPCRs in Tumorigenesis.
Record Nr. UNINA-9910150457103321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
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The ADME Encyclopedia [[electronic resource] ] : A Comprehensive Guide on Biopharmacy and Pharmacokinetics
The ADME Encyclopedia [[electronic resource] ] : A Comprehensive Guide on Biopharmacy and Pharmacokinetics
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021
Descrizione fisica 1 online resource (20 illus., 10 illus. in color.)
Disciplina 570
Soggetto topico Life sciences
Pharmacology
Pharmaceutical technology
Chemistry
Life Sciences, general
Pharmacology/Toxicology
Pharmaceutical Sciences/Technology
Chemistry/Food Science, general
ISBN 3-030-51519-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Drug Dissolution and Drug Release -- Drug Absorption -- Drug Distribution -- Drug Metabolism -- Drug Excretion -- Routes of Administration -- next Generation Drug Delivery Systems -- Pharmacogenomics -- Bioavailability and Bioequivalence -- Biopharmaceutical Drug Products -- Drug-Drug and Food-Drug Interactions -- In vitro and In silico ADME Predictions -- Drug Transporters -- Non-linear Pharmacokinetics -- Time Dependent Pharmacokinetics -- Pharmacometrics and Physiological Models.
Record Nr. UNINA-9910484249103321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021
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Advanced Bioactive Compounds Countering the Effects of Radiological, Chemical and Biological Agents : Strategies to Counter Biological Damage / / edited by Grant N. Pierce, Volodymyr I. Mizin, Alexander Omelchenko
Advanced Bioactive Compounds Countering the Effects of Radiological, Chemical and Biological Agents : Strategies to Counter Biological Damage / / edited by Grant N. Pierce, Volodymyr I. Mizin, Alexander Omelchenko
Edizione [1st ed. 2013.]
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013
Descrizione fisica 1 online resource (XVIII, 287 p. 67 illus.)
Disciplina 615
Collana NATO Science for Peace and Security Series A: Chemistry and Biology
Soggetto topico Pharmacology
Environmental health
Public health
Medicinal chemistry
Pharmacology/Toxicology
Environmental Health
Public Health
Medicinal Chemistry
ISBN 94-007-6513-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Targeting NF-κB to Prevent Radiation-Induced Carcinogenesis -- Antioxidants as a Bio-Shield against Radiological Weapons; Kedar -- Sensing Mechanisms of the Low-Power Infrared Radiation: From Molecular Target to Clinical Application -- Correction of the Cancer Therapy-Induced Anemia by the Grape Polyphenol Concentrate Enoant -- Radioprotective Properties of Seleno-Methionine with Methionine, Extracts from Basidium Fungi and Exogenous DNA -- Preventing the Harmful Health Effects of Biological Agents. Homocysteine: Neurotoxicity and Hyperexcitability -- Oxidation of Selected Lipids in Low Density Lipoprotein: Effects on Calcium Transients in Isolated Rabbit Cardiomyocytes -- Cerium Oxide Nanoparticles Counteract the Oxidative Stress in Cardiac Progenitor Cells -- Clinical Trial Complexity Measure – Balancing Constraints to Achieve Quality -- Bioactive Compounds from Natural Sources for Prophylaxis and Treatment of the Effects of Radiological, Chemical and Biological Agents. Systemic Approach in Determining the Role of Bioactive Compounds -- Ecological Potential of Plants -- The Protective Effects of Natural Polyphenolic Complexes of Grape Wine on Organisms Exposed to Oxidative and Nitrosative Stress under Diabetes Mellitus -- Protection of Subjects Participating in Clinical Trials -- Adaptive and Mal-Adaptive Signaling in Cells of the Cardiovascular System: Effect of Obesity-Associated Peptides on Human Blood Platelet Activation -- Spontaneous and Induced Mutagenesis: The Necessity and Possibilities of Prevention with the Grape Polyphenolic Concentrate Enoant -- Searching for New Antimicrobial Targets: Na+ Cycle in Energetics of Bacterial Pathogens -- Natural Antimutagens for Environmental Quality Management and Transition to Ecological Civilization -- Biotechnological and Therapeutical Aspects of Defense against Radiological, Chemical and Biological Agents. Grape Polyphenols Attenuate Psychological Stress -- Grape Cane as a Source of Trans-Resveratrol and Trans-Viniferin in the Technology of Biologically Active Compounds and Its Possible Applications -- The Effectiveness of Enoant in the Treatment of Bronchitis in Children -- Toxicology of Adipose Tissue (Adipotoxicology), or Adipose Tissue as a “Toxicrine” Organ -- Opportunity of Remediation of Radionuclide-Contaminated Soils and Growing Ecologically Pure Plant Material via Water-Retaining Polymer -- Bioactive Compounds of Crimean Wines Countering the Stress Experienced by Personnel -- Wine Components Normalize the Cytochrome P450 Content in the Liver and Kidneys of Rats under Neurogenic Stress.
Record Nr. UNINA-9910739406503321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013
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Advances in Cancer Biomarkers : From biochemistry to clinic for a critical revision / / edited by Roberto Scatena
Advances in Cancer Biomarkers : From biochemistry to clinic for a critical revision / / edited by Roberto Scatena
Edizione [1st ed. 2015.]
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015
Descrizione fisica 1 online resource (361 p.)
Disciplina 610.28
Collana Advances in Experimental Medicine and Biology
Soggetto topico Cancer research
Oncology  
Pharmacology
Cancer Research
Oncology
Pharmacology/Toxicology
ISBN 94-017-7215-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Prelims -- I Generality.- II Tumor markers-a critical revision -- Enzymes.- Hormones -- Oncofetal proteins.- Cytokeratins -- Carbohydrate markers -- Blood group antigens.- Genetic markers -- Various protein markers -- III Perspectives.- The role of Circulating tumor Cells as tumor markers -- Index.
Record Nr. UNINA-9910298445503321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015
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Lo trovi qui: Univ. Federico II
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Advances in Computational Toxicology : Methodologies and Applications in Regulatory Science / / edited by Huixiao Hong
Advances in Computational Toxicology : Methodologies and Applications in Regulatory Science / / edited by Huixiao Hong
Edizione [1st ed. 2019.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019
Descrizione fisica 1 online resource (416 pages)
Disciplina 025.066159
Collana Challenges and Advances in Computational Chemistry and Physics
Soggetto topico Chemoinformatics
Pharmacology
Bioinformatics 
Computational biology 
Chemistry, Physical and theoretical
Bioinformatics
Computer Applications in Chemistry
Pharmacology/Toxicology
Computer Appl. in Life Sciences
Theoretical and Computational Chemistry
Computational Biology/Bioinformatics
ISBN 3-030-16443-8
9783030164430
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Computational Toxicology Promotes Regulatory Science -- Tasks, Major Challenges and Emerging Modelling Methods for Computational Toxicology -- Xenobiotic Metabolism by Cytochrome P450s: Insights Gained from Molecular Simulations -- Applications of Molecular Modeling to Probe the Mechanism of Endocrine Disruptor Action -- Mixture Toxicity -- Towards reproducible in silico practice via OpenTox -- Combining Machine Learning and Multilayer Networks for Toxicity Prediction -- Matrix and tensor factorization for toxicity modelling -- Network-based In Silico Assessment of Drug Cardiotoxicity -- Mode-of-action-guided chemical toxicity prediction: A novel in silico approach for predictive toxicology -- Machine learning methods for toxicity analysis -- Predictive modeling of Tox21 data -- The NTP DrugMatrix Toxicogenomics Database and Analysis Tool -- Applications of Computational Toxicology for Risk Assessment of Food Ingredients and Indirect Food Additives -- In silico prediction of the point of departure (POD) with high throughput data -- The application of topic modeling on drug safety signal detection and analysis -- Molecular dynamics simulations and applications in computational toxicology -- Computational modeling for prediction of drug-induced liver injury in humans -- Genomics in vitro to in vivo extrapolation (GIVIVE) for drug safety evaluation.
Record Nr. UNINA-9910337929603321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019
Materiale a stampa
Lo trovi qui: Univ. Federico II
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