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Mass spectrometry in drug metabolism and pharmacokinetics [[electronic resource] /] / edited by Ragu Ramanathan
| Mass spectrometry in drug metabolism and pharmacokinetics [[electronic resource] /] / edited by Ragu Ramanathan |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2009 |
| Descrizione fisica | 1 online resource (403 p.) |
| Disciplina |
615.7
615/.7 |
| Altri autori (Persone) | RamanathanRagu |
| Soggetto topico |
Drugs - Design
Drugs - Metabolism - Research - Methodology Mass spectrometry Pharmacokinetics - Research - Methodology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-118-21157-X
1-282-68754-9 9786612687549 0-470-40981-9 0-470-40980-0 |
| Classificazione | VS 5300 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Mass Spectrometry in Drug Metabolism and Pharmacokinetics; Contents; Preface; About the Editor; Contributors; 1. Evolving Role of Mass Spectrometry in Drug Discovery and Development; 2. Quantitative Bioanalysis in Drug Discovery and Development: Principles and Applications; 3. Quadrupole, Triple-Quadrupole, and Hybrid Linear Ion Trap Mass Spectrometers for Metabolite Analysis; 4. Applications of Quadrupole Time-of-Flight Mass Spectrometry in Reactive Metabolite Screening; 5. Changing Role of FTMS in Drug Metabolism
6. High-Resolution LC-MS-Based Mass Defect Filter Approach: Basic Concept and Application in Metabolite Detection7. Applications of High-Sensitivity Mass Spectrometry and Radioactivity Detection Techniques in Drug Metabolism Studies; 8. Online Electrochemical-LC-MS Techniques for Profiling and Characterizing Metabolites and Degradants; 9. LC-MS Methods with Hydrogen/Deuterium Exchange for Identification of Hydroxylamine, N-Oxide, and Hydroxylated Analogs of Desloratadine; 10. Turbulent-Flow LC-MS: Applications for Accelerating Pharmacokinetic Profiling and Metabolite Identification 11. Desorption Ionization Techniques for Quantitative Analysis of Drug Molecules12. MALDI Imaging Mass Spectrometry for Direct Tissue Analysis of Pharmaceuticals; Index |
| Record Nr. | UNINA-9910144546603321 |
| Hoboken, N.J., : Wiley, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Mass spectrometry in drug metabolism and pharmacokinetics [[electronic resource] /] / edited by Ragu Ramanathan
| Mass spectrometry in drug metabolism and pharmacokinetics [[electronic resource] /] / edited by Ragu Ramanathan |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2009 |
| Descrizione fisica | 1 online resource (403 p.) |
| Disciplina |
615.7
615/.7 |
| Altri autori (Persone) | RamanathanRagu |
| Soggetto topico |
Drugs - Design
Drugs - Metabolism - Research - Methodology Mass spectrometry Pharmacokinetics - Research - Methodology |
| ISBN |
1-118-21157-X
1-282-68754-9 9786612687549 0-470-40981-9 0-470-40980-0 |
| Classificazione | VS 5300 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Mass Spectrometry in Drug Metabolism and Pharmacokinetics; Contents; Preface; About the Editor; Contributors; 1. Evolving Role of Mass Spectrometry in Drug Discovery and Development; 2. Quantitative Bioanalysis in Drug Discovery and Development: Principles and Applications; 3. Quadrupole, Triple-Quadrupole, and Hybrid Linear Ion Trap Mass Spectrometers for Metabolite Analysis; 4. Applications of Quadrupole Time-of-Flight Mass Spectrometry in Reactive Metabolite Screening; 5. Changing Role of FTMS in Drug Metabolism
6. High-Resolution LC-MS-Based Mass Defect Filter Approach: Basic Concept and Application in Metabolite Detection7. Applications of High-Sensitivity Mass Spectrometry and Radioactivity Detection Techniques in Drug Metabolism Studies; 8. Online Electrochemical-LC-MS Techniques for Profiling and Characterizing Metabolites and Degradants; 9. LC-MS Methods with Hydrogen/Deuterium Exchange for Identification of Hydroxylamine, N-Oxide, and Hydroxylated Analogs of Desloratadine; 10. Turbulent-Flow LC-MS: Applications for Accelerating Pharmacokinetic Profiling and Metabolite Identification 11. Desorption Ionization Techniques for Quantitative Analysis of Drug Molecules12. MALDI Imaging Mass Spectrometry for Direct Tissue Analysis of Pharmaceuticals; Index |
| Record Nr. | UNINA-9910831191603321 |
| Hoboken, N.J., : Wiley, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Mass spectrometry in drug metabolism and pharmacokinetics / / edited by Ragu Ramanathan
| Mass spectrometry in drug metabolism and pharmacokinetics / / edited by Ragu Ramanathan |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2009 |
| Descrizione fisica | 1 online resource (403 p.) |
| Disciplina | 615/.7 |
| Altri autori (Persone) | RamanathanRagu |
| Soggetto topico |
Drugs - Design
Drugs - Metabolism - Research - Methodology Mass spectrometry Pharmacokinetics - Research - Methodology |
| ISBN |
1-118-21157-X
1-282-68754-9 9786612687549 0-470-40981-9 0-470-40980-0 |
| Classificazione | VS 5300 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Mass Spectrometry in Drug Metabolism and Pharmacokinetics; Contents; Preface; About the Editor; Contributors; 1. Evolving Role of Mass Spectrometry in Drug Discovery and Development; 2. Quantitative Bioanalysis in Drug Discovery and Development: Principles and Applications; 3. Quadrupole, Triple-Quadrupole, and Hybrid Linear Ion Trap Mass Spectrometers for Metabolite Analysis; 4. Applications of Quadrupole Time-of-Flight Mass Spectrometry in Reactive Metabolite Screening; 5. Changing Role of FTMS in Drug Metabolism
6. High-Resolution LC-MS-Based Mass Defect Filter Approach: Basic Concept and Application in Metabolite Detection7. Applications of High-Sensitivity Mass Spectrometry and Radioactivity Detection Techniques in Drug Metabolism Studies; 8. Online Electrochemical-LC-MS Techniques for Profiling and Characterizing Metabolites and Degradants; 9. LC-MS Methods with Hydrogen/Deuterium Exchange for Identification of Hydroxylamine, N-Oxide, and Hydroxylated Analogs of Desloratadine; 10. Turbulent-Flow LC-MS: Applications for Accelerating Pharmacokinetic Profiling and Metabolite Identification 11. Desorption Ionization Techniques for Quantitative Analysis of Drug Molecules12. MALDI Imaging Mass Spectrometry for Direct Tissue Analysis of Pharmaceuticals; Index |
| Record Nr. | UNINA-9910878078503321 |
| Hoboken, N.J., : Wiley, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
