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Autophagy in current trends in cellular physiology and pathology / / edited by Nikolai V. Gorbunov, Marion Schneider
| Autophagy in current trends in cellular physiology and pathology / / edited by Nikolai V. Gorbunov, Marion Schneider |
| Pubbl/distr/stampa | Rijeka, Croatia : , : IntechOpen, , [2016] |
| Descrizione fisica | 1 online resource (x, 514 pages) : illustrations |
| Disciplina | 616.079 |
| Soggetto topico |
Phagocytosis
Cytology Autophagic vacuoles |
| ISBN |
953-51-4152-X
953-51-2727-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910317686003321 |
| Rijeka, Croatia : , : IntechOpen, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Autophagy in immunity and infection [[electronic resource] ] : a novel immune effector / / edited by Vojo Deretic
| Autophagy in immunity and infection [[electronic resource] ] : a novel immune effector / / edited by Vojo Deretic |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2006 |
| Descrizione fisica | 1 online resource (288 p.) |
| Disciplina | 616.079 |
| Altri autori (Persone) | DereticVojo |
| Soggetto topico | Phagocytosis |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-72356-4
9786610723560 3-527-60880-X 3-527-60854-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Autophagy in Immunity and Infection; Contents; Preface; Foreword; List of Contributors; Color Plates; Part I Introduction to Autophagy; 1 Overview of Autophagy; 1.1 Overview of Autophagy; 1.2 The Discovery of Autophagy; 1.3 Mechanistic Aspects of Autophagy; 1.3.1 Induction; 1.3.2 Cargo Selection and Packaging; 1.3.3 Vesicle Nucleation; 1.3.4 Vesicle Expansion and Completion; 1.3.5 Retrieval; 1.3.6 Targeting, Docking and Fusion of the Vesicle with the Lysosome/Vacuole; 1.3.7 Breakdown of the Vesicle and its Cargo; 1.4 Autophagy and Immunity; References
2 Cell Biology and Biochemistry of Autophagy2.1 Introduction; 2.2 Autophagic Pathway; 2.2.1 Formation of Autophagosomes; 2.2.2 Fusion of AV with Endocytic Pathways and Maturation; 2.2.3 Endosomes and Lysosomes; 2.3 Regulation of Mammalian Autophagy by Amino Acids and Hormones; 2.3.1 Amino Acids; 2.3.2 Hormones; 2.3.3 Longer-term Regulation; 2.3.4 The Nutrient Sensor Target of Rapamycin (TOR); 2.3.5 Upstream of TOR; 2.3.6 Downstream of TOR; 2.4 Methods to Measure Autophagy; 2.4.1 Microscopic Methods; 2.4.1.1 Electron Microscopy; 2.4.1.2 Light Microscopy; 2.4.2 Biochemical Methods 2.4.2.1 Formation and Induction2.4.2.2 Fusion; 2.4.2.3 Purification of Autophagosomes from Rat Liver; 2.4.2.4 Inhibition of Autophagy; 2.4.2.5 Common Questions; 2.4.3 Summary and Outlook; References; 3 Transgenic Models of Autophagy; 3.1 Molecular Mechanism of Mammalian Autophagy; 3.1.1 Atg12 Conjugation System; 3.1.2 Atg8/Microtubule-associated Protein 1 Light Chain 3 (LC3) Conjugation System; 3.1.3 Class III Phosphatidylinositol-3-kinase (PI3K) Complex; 3.1.4 Atg1 Kinase Complex; 3.1.5 Other Factors; 3.2 Autophagy Indicator Mice: Green Fluorescent Protein (GFP)-LC3 Transgenic Mice 3.3 Mouse Models Deficient for Autophagy-related Genes3.3.1 Atg5-deficient Mice; 3.3.2 Atg7-deficient Mice; 3.3.3 Beclin 1-deficient Mice; 3.4 Concluding Remarks; References; 4 Autophagy in Disease and Aging; 4.1 Introduction; 4.2 Autophagy in Neurodegenerative Disorders; 4.2.1 Protein Misfolding and Aggregation; 4.2.2 Parkinson's Disease; 4.2.3 Alzheimer's Disease; 4.2.4 Huntington's Disease; 4.2.5 Prion Diseases; 4.2.6 Niemann-Pick Type C; 4.3 Autophagy and Cancer; 4.3.1 Proteolysis of long-lived Proteins and Effect of Nutrient Deprivation in Cancer Cells 4.3.2 Autophagic Cell Death in Response to Anticancer Treatment4.3.3 Molecular Mechanisms; 4.3.3.1 Beclin 1; 4.3.3.2 PI3K-Akt-mTOR Pathway; 4.3.4 Possible Therapeutic Attempts; 4.4 Myopathies; 4.4.1 Danon Disease; 4.4.2 XMEA; 4.4.3 Rimmed Vacuolar Myopathies; 4.4.4 Other Myopathies; 4.4.5 Cardiomyopathies and Myocardial Cell Death; 4.5 Liver Diseases; 4.6 Diabetes Mellitus; 4.7 Aging; 4.7.1 Changes in Protein Degradation with Age; 4.7.2 Age-related Changes in Autophagy; 4.7.3 Consequences of the Failure of Autophagy in Aging; 4.7.4 Slowing Down Aging? 4.8 Concluding Remarks and Pending Questions |
| Record Nr. | UNINA-9910144556403321 |
| Weinheim, : Wiley-VCH, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Autophagy in immunity and infection [[electronic resource] ] : a novel immune effector / / edited by Vojo Deretic
| Autophagy in immunity and infection [[electronic resource] ] : a novel immune effector / / edited by Vojo Deretic |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2006 |
| Descrizione fisica | 1 online resource (288 p.) |
| Disciplina | 616.079 |
| Altri autori (Persone) | DereticVojo |
| Soggetto topico | Phagocytosis |
| ISBN |
1-280-72356-4
9786610723560 3-527-60880-X 3-527-60854-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Autophagy in Immunity and Infection; Contents; Preface; Foreword; List of Contributors; Color Plates; Part I Introduction to Autophagy; 1 Overview of Autophagy; 1.1 Overview of Autophagy; 1.2 The Discovery of Autophagy; 1.3 Mechanistic Aspects of Autophagy; 1.3.1 Induction; 1.3.2 Cargo Selection and Packaging; 1.3.3 Vesicle Nucleation; 1.3.4 Vesicle Expansion and Completion; 1.3.5 Retrieval; 1.3.6 Targeting, Docking and Fusion of the Vesicle with the Lysosome/Vacuole; 1.3.7 Breakdown of the Vesicle and its Cargo; 1.4 Autophagy and Immunity; References
2 Cell Biology and Biochemistry of Autophagy2.1 Introduction; 2.2 Autophagic Pathway; 2.2.1 Formation of Autophagosomes; 2.2.2 Fusion of AV with Endocytic Pathways and Maturation; 2.2.3 Endosomes and Lysosomes; 2.3 Regulation of Mammalian Autophagy by Amino Acids and Hormones; 2.3.1 Amino Acids; 2.3.2 Hormones; 2.3.3 Longer-term Regulation; 2.3.4 The Nutrient Sensor Target of Rapamycin (TOR); 2.3.5 Upstream of TOR; 2.3.6 Downstream of TOR; 2.4 Methods to Measure Autophagy; 2.4.1 Microscopic Methods; 2.4.1.1 Electron Microscopy; 2.4.1.2 Light Microscopy; 2.4.2 Biochemical Methods 2.4.2.1 Formation and Induction2.4.2.2 Fusion; 2.4.2.3 Purification of Autophagosomes from Rat Liver; 2.4.2.4 Inhibition of Autophagy; 2.4.2.5 Common Questions; 2.4.3 Summary and Outlook; References; 3 Transgenic Models of Autophagy; 3.1 Molecular Mechanism of Mammalian Autophagy; 3.1.1 Atg12 Conjugation System; 3.1.2 Atg8/Microtubule-associated Protein 1 Light Chain 3 (LC3) Conjugation System; 3.1.3 Class III Phosphatidylinositol-3-kinase (PI3K) Complex; 3.1.4 Atg1 Kinase Complex; 3.1.5 Other Factors; 3.2 Autophagy Indicator Mice: Green Fluorescent Protein (GFP)-LC3 Transgenic Mice 3.3 Mouse Models Deficient for Autophagy-related Genes3.3.1 Atg5-deficient Mice; 3.3.2 Atg7-deficient Mice; 3.3.3 Beclin 1-deficient Mice; 3.4 Concluding Remarks; References; 4 Autophagy in Disease and Aging; 4.1 Introduction; 4.2 Autophagy in Neurodegenerative Disorders; 4.2.1 Protein Misfolding and Aggregation; 4.2.2 Parkinson's Disease; 4.2.3 Alzheimer's Disease; 4.2.4 Huntington's Disease; 4.2.5 Prion Diseases; 4.2.6 Niemann-Pick Type C; 4.3 Autophagy and Cancer; 4.3.1 Proteolysis of long-lived Proteins and Effect of Nutrient Deprivation in Cancer Cells 4.3.2 Autophagic Cell Death in Response to Anticancer Treatment4.3.3 Molecular Mechanisms; 4.3.3.1 Beclin 1; 4.3.3.2 PI3K-Akt-mTOR Pathway; 4.3.4 Possible Therapeutic Attempts; 4.4 Myopathies; 4.4.1 Danon Disease; 4.4.2 XMEA; 4.4.3 Rimmed Vacuolar Myopathies; 4.4.4 Other Myopathies; 4.4.5 Cardiomyopathies and Myocardial Cell Death; 4.5 Liver Diseases; 4.6 Diabetes Mellitus; 4.7 Aging; 4.7.1 Changes in Protein Degradation with Age; 4.7.2 Age-related Changes in Autophagy; 4.7.3 Consequences of the Failure of Autophagy in Aging; 4.7.4 Slowing Down Aging? 4.8 Concluding Remarks and Pending Questions |
| Record Nr. | UNINA-9910830696103321 |
| Weinheim, : Wiley-VCH, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Autophagy in immunity and infection : a novel immune effector / / edited by Vojo Deretic
| Autophagy in immunity and infection : a novel immune effector / / edited by Vojo Deretic |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2006 |
| Descrizione fisica | 1 online resource (288 p.) |
| Disciplina | 616.07/9 |
| Altri autori (Persone) | DereticVojo |
| Soggetto topico | Phagocytosis |
| ISBN |
9786610723560
9781280723568 1280723564 9783527608805 352760880X 9783527608546 3527608540 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Autophagy in Immunity and Infection; Contents; Preface; Foreword; List of Contributors; Color Plates; Part I Introduction to Autophagy; 1 Overview of Autophagy; 1.1 Overview of Autophagy; 1.2 The Discovery of Autophagy; 1.3 Mechanistic Aspects of Autophagy; 1.3.1 Induction; 1.3.2 Cargo Selection and Packaging; 1.3.3 Vesicle Nucleation; 1.3.4 Vesicle Expansion and Completion; 1.3.5 Retrieval; 1.3.6 Targeting, Docking and Fusion of the Vesicle with the Lysosome/Vacuole; 1.3.7 Breakdown of the Vesicle and its Cargo; 1.4 Autophagy and Immunity; References
2 Cell Biology and Biochemistry of Autophagy2.1 Introduction; 2.2 Autophagic Pathway; 2.2.1 Formation of Autophagosomes; 2.2.2 Fusion of AV with Endocytic Pathways and Maturation; 2.2.3 Endosomes and Lysosomes; 2.3 Regulation of Mammalian Autophagy by Amino Acids and Hormones; 2.3.1 Amino Acids; 2.3.2 Hormones; 2.3.3 Longer-term Regulation; 2.3.4 The Nutrient Sensor Target of Rapamycin (TOR); 2.3.5 Upstream of TOR; 2.3.6 Downstream of TOR; 2.4 Methods to Measure Autophagy; 2.4.1 Microscopic Methods; 2.4.1.1 Electron Microscopy; 2.4.1.2 Light Microscopy; 2.4.2 Biochemical Methods 2.4.2.1 Formation and Induction2.4.2.2 Fusion; 2.4.2.3 Purification of Autophagosomes from Rat Liver; 2.4.2.4 Inhibition of Autophagy; 2.4.2.5 Common Questions; 2.4.3 Summary and Outlook; References; 3 Transgenic Models of Autophagy; 3.1 Molecular Mechanism of Mammalian Autophagy; 3.1.1 Atg12 Conjugation System; 3.1.2 Atg8/Microtubule-associated Protein 1 Light Chain 3 (LC3) Conjugation System; 3.1.3 Class III Phosphatidylinositol-3-kinase (PI3K) Complex; 3.1.4 Atg1 Kinase Complex; 3.1.5 Other Factors; 3.2 Autophagy Indicator Mice: Green Fluorescent Protein (GFP)-LC3 Transgenic Mice 3.3 Mouse Models Deficient for Autophagy-related Genes3.3.1 Atg5-deficient Mice; 3.3.2 Atg7-deficient Mice; 3.3.3 Beclin 1-deficient Mice; 3.4 Concluding Remarks; References; 4 Autophagy in Disease and Aging; 4.1 Introduction; 4.2 Autophagy in Neurodegenerative Disorders; 4.2.1 Protein Misfolding and Aggregation; 4.2.2 Parkinson's Disease; 4.2.3 Alzheimer's Disease; 4.2.4 Huntington's Disease; 4.2.5 Prion Diseases; 4.2.6 Niemann-Pick Type C; 4.3 Autophagy and Cancer; 4.3.1 Proteolysis of long-lived Proteins and Effect of Nutrient Deprivation in Cancer Cells 4.3.2 Autophagic Cell Death in Response to Anticancer Treatment4.3.3 Molecular Mechanisms; 4.3.3.1 Beclin 1; 4.3.3.2 PI3K-Akt-mTOR Pathway; 4.3.4 Possible Therapeutic Attempts; 4.4 Myopathies; 4.4.1 Danon Disease; 4.4.2 XMEA; 4.4.3 Rimmed Vacuolar Myopathies; 4.4.4 Other Myopathies; 4.4.5 Cardiomyopathies and Myocardial Cell Death; 4.5 Liver Diseases; 4.6 Diabetes Mellitus; 4.7 Aging; 4.7.1 Changes in Protein Degradation with Age; 4.7.2 Age-related Changes in Autophagy; 4.7.3 Consequences of the Failure of Autophagy in Aging; 4.7.4 Slowing Down Aging? 4.8 Concluding Remarks and Pending Questions |
| Record Nr. | UNINA-9911019734803321 |
| Weinheim, : Wiley-VCH, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Phagocytosis / / Joel A. Swanson
| Phagocytosis / / Joel A. Swanson |
| Autore | Swanson Joel A |
| Pubbl/distr/stampa | London, : Henry Stewart Talks, 2009 |
| Descrizione fisica | 1 online resource (1 streaming video file (39 min.) : color, sound) |
| Collana | Innate immunity : host recognition and response in health and disease |
| Soggetto topico |
Immunity, Innate
Phagocytosis |
| Formato | Videoregistrazioni  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Contents: Phagocytic cells -- The movements of Fc receptor-mediated phagocytosis -- Complement receptors -- Receptors associated with phagocytosis -- Movements of the actin cytoskeleton -- Many routes of entry into cells -- Coordination of signaling for phagocytosis -- How phagocytosis relates to immunity. |
| Record Nr. | UNINA-9910887856303321 |
Swanson Joel A
|
||
| London, : Henry Stewart Talks, 2009 | ||
| Videoregistrazioni | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Phagocytosis of dying cells : from molecular mechanisms to human diseases / Dmitri V. Krysko, Peter Vandenabeele editors
| Phagocytosis of dying cells : from molecular mechanisms to human diseases / Dmitri V. Krysko, Peter Vandenabeele editors |
| Pubbl/distr/stampa | [Dordrecht] : Springer, 2009 |
| Descrizione fisica | x, 447 p. : ill. ; 25 cm |
| Disciplina | 616.0799 |
| Altri autori (Persone) |
Krysko, Dmitri V.
Vandenabeele, Peterauthor |
| Soggetto topico |
Phagocytosis
Cell death |
| ISBN | 9781402092923 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISALENTO-991000101129707536 |
| [Dordrecht] : Springer, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
| ||
Soggetto topico
-
Phagocytosis
(6)
- Autophagic vacuoles (1)
- Cell death (1)
- Cytology (1)
- Immunity, Innate (1)