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Animal models for the study of human disease [[electronic resource] /] / edited by P. Michael Conn
| Animal models for the study of human disease [[electronic resource] /] / edited by P. Michael Conn |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Elsevier, 2013 |
| Descrizione fisica | 1 online resource (1109 p.) |
| Disciplina | 616.0273 |
| Altri autori (Persone) | ConnP. Michael |
| Soggetto topico |
Diseases - Animal models
Laboratory animals Pathology, Experimental |
| Soggetto genere / forma | Electronic books. |
| ISBN | 0-12-415912-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; ANIMAL MODELS FOR THE STUDY OF HUMAN DISEASE; Copyright; Contents; Preface; List of Contributors; Part I -ETHICS, RESOURCES AND APPROACHES; Chapter 1 - Ethics in Biomedical Animal Research: The Key Role of the Investigator; NATURE AND SCOPE OF THE CHAPTER; THE SUBJECT MATTER OF ANIMAL RESEARCH ETHICS; ASPECTS OF ANIMAL USE AND CARE RELEVANT TO ANIMAL RESEARCH ETHICS; WHY INVESTIGATORS ARE UNIQUELY QUALIFIED TO ENGAGE IN ETHICAL ASSESSMENT OF ANIMAL RESEARCH; WHY INVESTIGATORS SHOULD COMMIT THEMSELVES TO ETHICAL CONDUCT OF ANIMAL RESEARCH
WHY INVESTIGATORS PLAY THE KEY ROLE IN ASSURING THE ETHICAL CONDUCT OF ANIMAL RESEARCH PROJECTS SOURCES OF SUPPORT AND GUIDANCE IN CONDUCTING ETHICAL RESEARCH; DEVELOPING USEFUL ETHICAL GUIDELINES; FUNDAMENTAL PRINCIPLES OF ANIMAL RESEARCH ETHICS; PRACTICAL ETHICAL GUIDELINES FOR INVESTIGATORS; SOME CURRENT DIFFICULT ISSUES IN ANIMAL RESEARCH ETHICS; GENERAL SUGGESTIONS FOR INVESTIGATORS; References; Chapter 2 - Access to Resources: A Model Organism Database for Humans; THE PROBLEM; THE LAMHDI SOLUTION; THE IDEAL SOLUTION; Acknowledgments; References Chapter 3 - The Advent of the Golden Era of Animal Alternatives INTRODUCTION; ANALYTICAL TOOLS FOR THE DETECTION OF FOOD-BORNE DISEASE; AN INVITRO SYSTEM TO ASSESS ADVERSE EFFECTS DURING DEVELOPMENT; DISEASES-IN-A-DISH; NONINVASIVE IMAGING AND RECORDING; CONCLUSIONS; References; Chapter 4 - Environmental Enrichment for Animals Used in Research; INTRODUCTION; APPLIED SCIENCE: ENRICHMENT AS A WELFARE TOOL; BASIC SCIENCE: ENRICHMENT AND ANIMAL MODELS; ENRICHMENT AND EXPERIMENTAL VARIABILITY; ENVIRONMENTAL ENRICHMENT REGULATIONS; IMPLEMENTING AN ENRICHMENT PLAN; CONCLUSIONS; Acknowledgments References Part II -VISION; Chapter 5 - Animal Models of Age-Related Macular Degeneration; INTRODUCTION; COMPARATIVE RETINAL ANATOMY AND THE PATHOLOGY OF AMD; THE GENETICS OF AMD; INFLAMMATION IN AMD; HTRA1 AND LOC387715/ARMS2 IN AMD; OXIDATIVE DAMAGE AND AMD; LIPID METABOLISM AND AMD; SPONTANEOUSLY OCCURRING PRIMATE MODELS OF AMD; MODELING CHOROIDAL NEOVASCULARIZATION IN ADVANCED AMD; CONCLUSION; References; Chapter 6 - N-Methyl-N-Nitrosourea Animal Models for Retinitis Pigmentosa; INTRODUCTION; TIME-COURSE PROGRESSION OF MNU-INDUCED RETINAL DEGENERATION RETINAL DEGENERATION CAUSED BY MNU IN VARIOUS ANIMAL SPECIESAGE-RELATED PHOTORECEPTOR CELL DAMAGE AND SENSITIVITY TO MNU; PHOTORECEPTOR CELL DEATH, CELL DEBRIS REMOVAL, AND RPE CELL MIGRATION; MOLECULAR MECHANISMS IN PHOTORECEPTOR CELL DEATH CAUSED BY MNU; THERAPEUTIC TRIALS AGAINST MNU-INDUCED PHOTORECEPTOR APOPTOSIS; CONCLUDING REMARKS; Acknowledgments; References; Part III -CARDIAC AND CARDIOVASCULAR; Chapter 7 - Animal Models of Myocardial Disease; INTRODUCTION; THE SPECTRUM OF CARDIOVASCULAR DISEASE; CHOICE OF ANIMAL SYSTEM; EXPERIMENTAL DESIGN; ISCHEMIC HEART DISEASE SYSTOLIC HEART FAILURE |
| Record Nr. | UNINA-9910459131603321 |
| London, : Elsevier, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Animal models for the study of human disease / / edited by P. Michael Conn
| Animal models for the study of human disease / / edited by P. Michael Conn |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Elsevier, 2013 |
| Descrizione fisica | 1 online resource (xviii, 1089 pages) : illustrations (some color) |
| Disciplina | 616.0273 |
| Collana | Gale eBooks |
| Soggetto topico |
Diseases - Animal models
Laboratory animals Pathology, Experimental |
| ISBN | 0-12-415912-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; ANIMAL MODELS FOR THE STUDY OF HUMAN DISEASE; Copyright; Contents; Preface; List of Contributors; Part I -ETHICS, RESOURCES AND APPROACHES; Chapter 1 - Ethics in Biomedical Animal Research: The Key Role of the Investigator; NATURE AND SCOPE OF THE CHAPTER; THE SUBJECT MATTER OF ANIMAL RESEARCH ETHICS; ASPECTS OF ANIMAL USE AND CARE RELEVANT TO ANIMAL RESEARCH ETHICS; WHY INVESTIGATORS ARE UNIQUELY QUALIFIED TO ENGAGE IN ETHICAL ASSESSMENT OF ANIMAL RESEARCH; WHY INVESTIGATORS SHOULD COMMIT THEMSELVES TO ETHICAL CONDUCT OF ANIMAL RESEARCH
WHY INVESTIGATORS PLAY THE KEY ROLE IN ASSURING THE ETHICAL CONDUCT OF ANIMAL RESEARCH PROJECTS SOURCES OF SUPPORT AND GUIDANCE IN CONDUCTING ETHICAL RESEARCH; DEVELOPING USEFUL ETHICAL GUIDELINES; FUNDAMENTAL PRINCIPLES OF ANIMAL RESEARCH ETHICS; PRACTICAL ETHICAL GUIDELINES FOR INVESTIGATORS; SOME CURRENT DIFFICULT ISSUES IN ANIMAL RESEARCH ETHICS; GENERAL SUGGESTIONS FOR INVESTIGATORS; References; Chapter 2 - Access to Resources: A Model Organism Database for Humans; THE PROBLEM; THE LAMHDI SOLUTION; THE IDEAL SOLUTION; Acknowledgments; References Chapter 3 - The Advent of the Golden Era of Animal Alternatives INTRODUCTION; ANALYTICAL TOOLS FOR THE DETECTION OF FOOD-BORNE DISEASE; AN INVITRO SYSTEM TO ASSESS ADVERSE EFFECTS DURING DEVELOPMENT; DISEASES-IN-A-DISH; NONINVASIVE IMAGING AND RECORDING; CONCLUSIONS; References; Chapter 4 - Environmental Enrichment for Animals Used in Research; INTRODUCTION; APPLIED SCIENCE: ENRICHMENT AS A WELFARE TOOL; BASIC SCIENCE: ENRICHMENT AND ANIMAL MODELS; ENRICHMENT AND EXPERIMENTAL VARIABILITY; ENVIRONMENTAL ENRICHMENT REGULATIONS; IMPLEMENTING AN ENRICHMENT PLAN; CONCLUSIONS; Acknowledgments References Part II -VISION; Chapter 5 - Animal Models of Age-Related Macular Degeneration; INTRODUCTION; COMPARATIVE RETINAL ANATOMY AND THE PATHOLOGY OF AMD; THE GENETICS OF AMD; INFLAMMATION IN AMD; HTRA1 AND LOC387715/ARMS2 IN AMD; OXIDATIVE DAMAGE AND AMD; LIPID METABOLISM AND AMD; SPONTANEOUSLY OCCURRING PRIMATE MODELS OF AMD; MODELING CHOROIDAL NEOVASCULARIZATION IN ADVANCED AMD; CONCLUSION; References; Chapter 6 - N-Methyl-N-Nitrosourea Animal Models for Retinitis Pigmentosa; INTRODUCTION; TIME-COURSE PROGRESSION OF MNU-INDUCED RETINAL DEGENERATION RETINAL DEGENERATION CAUSED BY MNU IN VARIOUS ANIMAL SPECIESAGE-RELATED PHOTORECEPTOR CELL DAMAGE AND SENSITIVITY TO MNU; PHOTORECEPTOR CELL DEATH, CELL DEBRIS REMOVAL, AND RPE CELL MIGRATION; MOLECULAR MECHANISMS IN PHOTORECEPTOR CELL DEATH CAUSED BY MNU; THERAPEUTIC TRIALS AGAINST MNU-INDUCED PHOTORECEPTOR APOPTOSIS; CONCLUDING REMARKS; Acknowledgments; References; Part III -CARDIAC AND CARDIOVASCULAR; Chapter 7 - Animal Models of Myocardial Disease; INTRODUCTION; THE SPECTRUM OF CARDIOVASCULAR DISEASE; CHOICE OF ANIMAL SYSTEM; EXPERIMENTAL DESIGN; ISCHEMIC HEART DISEASE SYSTOLIC HEART FAILURE |
| Record Nr. | UNINA-9910792482703321 |
| London, : Elsevier, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Animal models for the study of human disease / / edited by P. Michael Conn
| Animal models for the study of human disease / / edited by P. Michael Conn |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Elsevier, 2013 |
| Descrizione fisica | 1 online resource (xviii, 1089 pages) : illustrations (some color) |
| Disciplina | 616.0273 |
| Collana | Gale eBooks |
| Soggetto topico |
Diseases - Animal models
Laboratory animals Pathology, Experimental |
| ISBN | 0-12-415912-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; ANIMAL MODELS FOR THE STUDY OF HUMAN DISEASE; Copyright; Contents; Preface; List of Contributors; Part I -ETHICS, RESOURCES AND APPROACHES; Chapter 1 - Ethics in Biomedical Animal Research: The Key Role of the Investigator; NATURE AND SCOPE OF THE CHAPTER; THE SUBJECT MATTER OF ANIMAL RESEARCH ETHICS; ASPECTS OF ANIMAL USE AND CARE RELEVANT TO ANIMAL RESEARCH ETHICS; WHY INVESTIGATORS ARE UNIQUELY QUALIFIED TO ENGAGE IN ETHICAL ASSESSMENT OF ANIMAL RESEARCH; WHY INVESTIGATORS SHOULD COMMIT THEMSELVES TO ETHICAL CONDUCT OF ANIMAL RESEARCH
WHY INVESTIGATORS PLAY THE KEY ROLE IN ASSURING THE ETHICAL CONDUCT OF ANIMAL RESEARCH PROJECTS SOURCES OF SUPPORT AND GUIDANCE IN CONDUCTING ETHICAL RESEARCH; DEVELOPING USEFUL ETHICAL GUIDELINES; FUNDAMENTAL PRINCIPLES OF ANIMAL RESEARCH ETHICS; PRACTICAL ETHICAL GUIDELINES FOR INVESTIGATORS; SOME CURRENT DIFFICULT ISSUES IN ANIMAL RESEARCH ETHICS; GENERAL SUGGESTIONS FOR INVESTIGATORS; References; Chapter 2 - Access to Resources: A Model Organism Database for Humans; THE PROBLEM; THE LAMHDI SOLUTION; THE IDEAL SOLUTION; Acknowledgments; References Chapter 3 - The Advent of the Golden Era of Animal Alternatives INTRODUCTION; ANALYTICAL TOOLS FOR THE DETECTION OF FOOD-BORNE DISEASE; AN INVITRO SYSTEM TO ASSESS ADVERSE EFFECTS DURING DEVELOPMENT; DISEASES-IN-A-DISH; NONINVASIVE IMAGING AND RECORDING; CONCLUSIONS; References; Chapter 4 - Environmental Enrichment for Animals Used in Research; INTRODUCTION; APPLIED SCIENCE: ENRICHMENT AS A WELFARE TOOL; BASIC SCIENCE: ENRICHMENT AND ANIMAL MODELS; ENRICHMENT AND EXPERIMENTAL VARIABILITY; ENVIRONMENTAL ENRICHMENT REGULATIONS; IMPLEMENTING AN ENRICHMENT PLAN; CONCLUSIONS; Acknowledgments References Part II -VISION; Chapter 5 - Animal Models of Age-Related Macular Degeneration; INTRODUCTION; COMPARATIVE RETINAL ANATOMY AND THE PATHOLOGY OF AMD; THE GENETICS OF AMD; INFLAMMATION IN AMD; HTRA1 AND LOC387715/ARMS2 IN AMD; OXIDATIVE DAMAGE AND AMD; LIPID METABOLISM AND AMD; SPONTANEOUSLY OCCURRING PRIMATE MODELS OF AMD; MODELING CHOROIDAL NEOVASCULARIZATION IN ADVANCED AMD; CONCLUSION; References; Chapter 6 - N-Methyl-N-Nitrosourea Animal Models for Retinitis Pigmentosa; INTRODUCTION; TIME-COURSE PROGRESSION OF MNU-INDUCED RETINAL DEGENERATION RETINAL DEGENERATION CAUSED BY MNU IN VARIOUS ANIMAL SPECIESAGE-RELATED PHOTORECEPTOR CELL DAMAGE AND SENSITIVITY TO MNU; PHOTORECEPTOR CELL DEATH, CELL DEBRIS REMOVAL, AND RPE CELL MIGRATION; MOLECULAR MECHANISMS IN PHOTORECEPTOR CELL DEATH CAUSED BY MNU; THERAPEUTIC TRIALS AGAINST MNU-INDUCED PHOTORECEPTOR APOPTOSIS; CONCLUDING REMARKS; Acknowledgments; References; Part III -CARDIAC AND CARDIOVASCULAR; Chapter 7 - Animal Models of Myocardial Disease; INTRODUCTION; THE SPECTRUM OF CARDIOVASCULAR DISEASE; CHOICE OF ANIMAL SYSTEM; EXPERIMENTAL DESIGN; ISCHEMIC HEART DISEASE SYSTOLIC HEART FAILURE |
| Record Nr. | UNINA-9910808758703321 |
| London, : Elsevier, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The British journal of experimental pathology
| The British journal of experimental pathology |
| Pubbl/distr/stampa | [London], : [H.K. Lewis & Co Ltd], [1920-1989] |
| Disciplina | 616.07/05 |
| Soggetto topico |
Pathology, Experimental
Pathology Pathologie expérimentale Pathologie |
| Soggetto genere / forma |
Periodical
periodicals. Periodicals. Périodiques. |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Experimental pathology
Br J Exp Pathol |
| Record Nr. | UNISA-996200635903316 |
| [London], : [H.K. Lewis & Co Ltd], [1920-1989] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
The British journal of experimental pathology
| The British journal of experimental pathology |
| Pubbl/distr/stampa | [London], : [H.K. Lewis & Co Ltd], [1920-1989] |
| Disciplina | 616.07/05 |
| Soggetto topico |
Pathology, Experimental
Pathology Pathologie expérimentale Pathologie |
| Soggetto genere / forma |
Periodical
periodicals. Periodicals. Périodiques. |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Experimental pathology
Br J Exp Pathol |
| Record Nr. | UNINA-9910143373503321 |
| [London], : [H.K. Lewis & Co Ltd], [1920-1989] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Experimental and molecular pathology
| Experimental and molecular pathology |
| Pubbl/distr/stampa | [San Diego], : Academic Press |
| Disciplina | 616 |
| Soggetto topico |
Pathology, Molecular
Pathology, Experimental Pathologie moléculaire Pathologie expérimentale |
| Soggetto genere / forma | Periodicals. |
| ISSN | 1096-0945 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996205246803316 |
| [San Diego], : Academic Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Experimental and molecular pathology
| Experimental and molecular pathology |
| Pubbl/distr/stampa | [San Diego], : Academic Press |
| Disciplina | 616 |
| Soggetto topico |
Pathology, Molecular
Pathology, Experimental Pathology Periodicals Pathologie moléculaire Pathologie expérimentale |
| Soggetto genere / forma | Periodicals. |
| ISSN | 1096-0945 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910146365503321 |
| [San Diego], : Academic Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
International journal of clinical and experimental pathology
| International journal of clinical and experimental pathology |
| Pubbl/distr/stampa | Madison, WI, : E-Century Pub. Corp., [2008]- |
| Descrizione fisica | 1 online resource |
| Disciplina | 616 |
| Soggetto topico |
Diagnosis, Laboratory
Pathology, Experimental Pathology Pathology, Clinical |
| Soggetto genere / forma |
Periodicals.
Fulltext Internet Resources. Periodical |
| Soggetto non controllato | Pathology |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | IJCEP |
| Record Nr. | UNISA-996206056003316 |
| Madison, WI, : E-Century Pub. Corp., [2008]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
International journal of clinical and experimental pathology
| International journal of clinical and experimental pathology |
| Pubbl/distr/stampa | Madison, WI, : E-Century Pub. Corp., [2008]- |
| Descrizione fisica | 1 online resource |
| Disciplina | 616 |
| Soggetto topico |
Diagnosis, Laboratory
Pathology, Experimental Pathology Pathology, Clinical |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | IJCEP |
| Record Nr. | UNINA-9910142274403321 |
| Madison, WI, : E-Century Pub. Corp., [2008]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
International journal of experimental pathology
| International journal of experimental pathology |
| Pubbl/distr/stampa | [Oxford, U.K.], : Blackwell Scientific Publications, [1990]- |
| Disciplina | 616.07 |
| Soggetto topico |
Pathology, Experimental
Pathology Pathologic Processes Pathologie expérimentale |
| Soggetto genere / forma |
Periodical
periodicals. Periodicals. Périodique électronique (Descripteur de forme) Ressource Internet (Descripteur de forme) Périodiques. |
| ISSN | 1365-2613 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Experimental pathology
Int J Exp Pathol |
| Record Nr. | UNISA-996204829603316 |
| [Oxford, U.K.], : Blackwell Scientific Publications, [1990]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
