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Cannabinoids and pain / / Samer N. Narouze, editor
| Cannabinoids and pain / / Samer N. Narouze, editor |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (xix, 339 pages) : illustrations (black and white) |
| Disciplina | 615.7827 |
| Soggetto topico |
Cannabinoids - Therapeutic use
Pain - Chemotherapy Cànnabis Ús terapèutic |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
9783030691868
3-030-69186-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Part I: Introduction to Cannabis -- 1: History of Cannabis -- 2: Cannabis Regulations -- Introduction -- Federal Regulations -- State Cannabis Laws -- Research Expansion -- Conclusion -- 3: The Demand for Medical Cannabis Education -- 4: Pain Physicians and Medical Cannabis: Attitudes, Believes, Preparedness and Knowledge -- Introduction -- Development and Description of the Applied Questionnaire -- Statistical Analysis -- Results -- Discussion -- Summary -- Medical Cannabis Questionnaire -- 5: Cannabis Terminology -- Introduction -- General Aspects of the Cannabis Plant -- Differences Between C. sativa and C. indica -- Cannabis Versus Hemp -- The Endocannabinoid System (ECS) -- Key Terminology -- Cannabis Products and Accessories -- Conclusion -- Part II: Cannabinoids Pharmacology -- 6: The Endocannabinoid System -- Introduction -- Brief History of Cannabis and Hemp -- Components of the Endocannabinoid System (ECS) -- eCBs and Their Signal Transduction Pathways -- Complexity of the Endogenous Cannabinoid System -- CB1 and CB2 Receptor -- Other Receptors -- Transporters -- Enzymes -- Physiological Actions of ECS -- 7: Cannabinoid Receptor 1 (CB1) -- CB1 Receptors -- CB1 Receptor Physiology, Pathology, and Pharmacology -- CB1 Signaling -- CB1 Receptor Distribution -- Neocortex -- Hippocampus -- Hypothalamic -- Midbrain Periaqueductal Gray -- Brain Stem Rostral Ventromedial Medulla -- Tolerance -- CB1 Receptor Ligands -- References -- 8: Cannabinoid Receptor 2 (CB2) -- Cannabinoid 2 Receptor -- CB2 Receptor Physiology and Pharmacology -- CB2 Receptor Distribution -- CB2 Signaling -- CB2 Chronic Pain Models -- Tolerance -- CB2 Receptor Ligands.
9: Endocannabinoids: Anandamide and 2-Arachidonoylglycerol (2-AG) -- Introduction -- Biosynthesis and Breakdown Pathways -- Anandamide -- 2-AG -- Endocannabinoids' Mechanism of Action -- Anandamide -- 2-AG -- Plasticity of Endocannabinoid Signaling -- Endocannabinoids in Pain -- Peripheral Mechanisms -- Spinal Mechanisms -- Supraspinal Mechanisms -- Conclusion -- 10: Phytocannabinoids: Tetrahydrocannabinol (THC) -- Phytocannabinoids -- Introduction -- Δ9-Tetrahydrocannabinol (THC) -- Mechanism of Action of THC -- Applied Pharmacology and Pharmacokinetics -- Absorption -- Smoking -- Oral -- Oro-mucosal and Intranasal -- Rectal -- Transcutaneous -- Distribution -- Metabolism and Elimination -- Conclusion -- 11: Phytocannabinoids: Cannabidiol (CBD) -- Phytocannabinoids -- Cannabidiol and Its Various Clinical Effects -- Pharmacodynamics of Cannabidiol -- Applied Pharmacology and Pharmacokinetics -- Smoking -- Oral -- Transcutaneous -- Volume of Distribution -- Metabolism -- Elimination -- Safety Profile and Side Effects -- Cannabidiol Interaction with Tetrahydrocannabinol -- Conclusion -- 12: Other Phytocannabinoids -- Introduction -- Synthesis of Phytocannabinoids -- Cannabinoids and the Endocannabinoid System (ECS) -- Minor Cannabinoids -- Cannabinol (CBN) -- Cannabigerol (CBG) -- Cannabichromene (CBC) -- Tetrahydrocannabivarin (THCV) -- Conclusion -- 13: Cannabis Drug Interactions -- Introduction -- Routes of Administration -- Cannabinoid Drug Interactions -- Specific Drug Interactions -- Over-the-Counter (OTC) Analgesics -- Neuropathic Agents -- Opiates -- Antiepileptics -- Psychotropics -- Anticoagulants and Antiplatelets: "Blood Thinners" -- Warfarin -- Direct Oral Anticoagulants -- Clopidogrel -- Heparin/Fondaparinux -- References -- Part III: Pharmaceutical Cannabinoids. 14: Dronabinol (Marinol®) -- Introduction -- Mechanism of Action -- Pharmacokinetics -- Therapeutic Use -- Safety, Toxicity, and Adverse Effects -- 15: Nabilone (Cesamet) -- Introduction -- Clinical Trials -- Pharmacology and Pharmacokinetics -- Dosage and Administration -- Monitoring, Adverse Events, Drug Interactions, and Abuse Potential -- Adverse Effects -- Drug Interactions -- Abuse Potential -- 16: Cannabidiol (Epidiolex) -- Introduction -- Clinical Trials -- Pharmacology and Pharmacokinetics -- Dosage and Administration -- Monitoring, Adverse Events, and Drug Interactions -- Adverse Effects -- Abuse Potential -- 17: Nabiximols (Sativex®) -- Introduction -- Nabiximols Production -- Nabiximols Approval and Indications -- Nabiximols Contraindication -- Nabiximols Evidence -- Nabiximols for MS-Related Spasticity -- Nabiximols for MS-Related Neuropathic Pain -- Nabiximols for Cancer-Related Pain -- Nabiximols for Chronic Pain -- Nabiximols Tolerability -- Nabiximols Dosage and Administration -- Administration -- Dosing -- Storage, Stability, and Dosage Form -- Storage and Stability -- Dosage Form -- Summary -- Part IV: Medical Cannabis -- 18: Cannabis Strains to Chemovars -- Introduction -- Cannabis sativa L. -- Cannabis Cultivation and Trichomes -- Importance of Trichomes -- Cannabis Constituents -- Cannabinoids -- Terpenoids -- Other Cannabis Compounds -- Entourage Effect of Cannabis Constituents -- Cannabis Classification: Strains Versus Chemovars -- Strains -- Chemovar -- Practical Chemovar Selection for Clinicians -- Summary -- 19: The Model of a Medical Cannabis Clinic -- Introduction -- Description of a Medical Cannabis Clinic -- Referral and Screening -- Initial Visit -- Follow-Up and Monitoring -- Patient Education and Physician Communication. Protocols and Procedure Guidelines -- Continuing Medical Education -- Research Development -- Conclusion -- References -- 20: Barriers for the Prescription of Cannabinoid-Based Medicines -- Introduction -- Barriers for Cannabinoid Prescription -- Social Stigma for the Use of Cannabis -- Myths Versus Realities of Medical Cannabis Use -- Research Gaps and Limitations to Justify Medical Cannabis Use -- Lack of Knowledge Regarding Cannabis Regulatory Frameworks -- Limited Medical Cannabis Education -- Development of Medical Cannabis Education Programs with High Scientific Content -- Conclusion -- 21: Practical Recommendations for the Use of Medical Cannabis -- Introduction -- Cannabinoid-Based Medicines: What Is Currently Available? -- Prescription or Pharmaceutical Cannabinoids -- Natural Cannabis -- Inhalation -- Practical Recommendations [11, 12] -- Oral Administration -- Practical Recommendations [11, 12] -- Therapeutic Properties of Cannabinoids: THC Versus CBD -- Practical Recommendations for the Prescription of Cannabinoid-Based Medicines -- Clinical Evidence to Support Cannabinoid Use in Specific Medical Conditions -- Is the Patient a Candidate for Cannabinoid Therapy? A Systematic Approach -- Conclusion -- 22: Cannabinoid-Based Medicines: Dosing, Titration & -- Monitoring -- Introduction -- Methods of Administration -- Inhalation: Smoking and Vaporizing -- Oral -- Oromucosal -- Topical -- Dosing -- Concentration and Potency -- Cannabis Flower Dosing -- Cannabis Oil Dosing -- Achieving Optimal Therapeutic Dose and Cannabis Rotation -- Cannabis Chemovar Rotation and Reduction -- Monitoring -- Summary -- 23: Cannabinoid-Based Medicines: Patient Safety Considerations -- Introduction -- Practical Considerations for Cannabis Use -- Considerations -- Immunocompromised Patients. Calcineurin Inhibitors, Protein Disulfide Isomerase (PD1) Inhibitors, and Biologics -- Chronic Kidney Disease -- Older Adults and Patients with Concurrent Medical Conditions -- Polypharmacy and Drug Interactions [10] -- Precautions -- Concurrent Active Mood or Anxiety Disorder -- Patients with Risk Factors for Cardiovascular Disease (CVD) -- Tobacco Use -- E-Cigarette Use -- Severe Liver Dysfunction or Disease -- Medications Associated with Sedation or Cognitive Impairment -- Driving and Safety Sensitive Occupations -- Relative Contraindications -- Individuals Under the Age of 25 -- Cannabis Use Disorder (CUD) -- Substance Use Disorder (SUD) and Consideration for Harm Reduction -- Contraindications -- Cardiovascular Disease -- Respiratory Disease -- Psychosis and Bipolar Disorders -- Pregnancy and Breastfeeding -- Summary -- Part V: Cannabinoids and Pain -- 24: Cannabinoids and Pain: Mechanisms of Action -- Introduction -- Endocannabinoids' Mechanism of Action -- Anandamide (AEA) -- 2-Arachidonoylglycerol (2-AG) -- Endocannabinoids and Pain Modulation -- Peripheral Mechanisms -- Spinal Mechanisms -- Supraspinal Mechanisms -- Anandamide and 2-AG Synergistic Effect -- Endocannabinoid Receptors -- CB1 Receptors -- Central CB1 Receptors -- Peripheral CB1 Receptors -- Central CB2 Receptors -- Peripheral CB2 Receptors -- Other Putative Endocannabinoid Receptors: TRPV1 and GPR55 -- TRPV1 -- GPR55 -- Phytocannabinoids (THC and CBD) -- THC -- CBD -- Mechanisms of Action in Pain Modulation -- THC -- CBD -- References -- 25: Cannabinoids and Pain: Clinical Evidence -- Introduction -- Chronic Non-cancer Pain -- Chronic Neuropathic Pain -- Fibromyalgia -- Rheumatoid Arthritis -- Cancer Pain -- Acute Nociceptive Pain -- Summary -- 26: Cannabinoids and Cancer Pain -- Introduction -- Relevant Mechanisms of Cancer Pain. Current Understanding of Clinical Studies. |
| Record Nr. | UNINA-9910488702303321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Opioid therapy in the 21st century / / edited by Howard S. Smith
| Opioid therapy in the 21st century / / edited by Howard S. Smith |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Oxford, England ; ; New York : , : Oxford University Press, , 2013 |
| Descrizione fisica | 1 online resource (307 pages) : illustrations |
| Disciplina | 615/.7822 |
| Collana | Oxford American Pain Library |
| Soggetto topico |
Pain - drug therapy
Pain - Chemotherapy Opioids - Therapeutic use |
| Soggetto genere / forma | Electronic books. |
| ISBN | 0-19-023675-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910465567603321 |
| Oxford, England ; ; New York : , : Oxford University Press, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Opioid therapy in the 21st century / / edited by Howard S. Smith
| Opioid therapy in the 21st century / / edited by Howard S. Smith |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Oxford, England ; ; New York : , : Oxford University Press, , 2013 |
| Descrizione fisica | 1 online resource (307 pages) : illustrations |
| Disciplina | 615/.7822 |
| Collana | Oxford American Pain Library |
| Soggetto topico |
Pain - drug therapy
Pain - Chemotherapy Opioids - Therapeutic use |
| ISBN | 0-19-023675-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction to opioids / Howard S. Smith -- Overview of opioid-related terminology / Kenneth C. Jackson II and Howard S. Smith -- Diagnosis and assessment of pain / Charles E. Argoff and Andrew Dubin -- Opioid pharmacology / Mellar P. Davis and Howard S. Smith -- Optimizing pharmacologic outcomes : drug selection / Kenneth C. Jackson II & Howard S. Smith -- Optimizing pharmacologic outcomes : route selection / Howard S. Smith -- Optimizing pharmacologic outcomes : assessing and managing opioid side effects / Howard S. Smith, Gary McCleane, and Gary Thompson -- Opioid-induced hyperalgesia / Lucy Chen and Jianren Mao -- Optimizing pharmacologic outcomes : principles of opioid rotation / Howard S. Smith and Bill H. McCarberg -- Optimizing pharmacologic outcomes : individualization of therapy / Howard S. Smith -- Opioid therapy for cancer pain / Mellar P. Davis and Howard S. Smith -- Evidence for the use of long-term opioid therapy in persistent noncancer pain / Howard S. Smith, Gary McCleane and Gary Thompson -- Pre-opioid prescribing period / Howard S. Smith -- Identifying patients at risk for pain medication misuse / Lynn R. Webster and Howard S. Smith -- Potential documentation tools in long-term opioid therapy / Howard S. Smith and Kenneth L. Kirsh -- Managing the risk of abuse, addiction, and diversion / Howard S. Smith -- Special populations : pediatric / Amy Mitchell and Howard S. Smith -- Special populations : geriatric / Gary McCleane -- Special populations : palliative care / Lida Nabati and Janet Abrahm -- Patients with a history of substance abuse / Kenneth L. Kirsh and Steven D. Passik. |
| Record Nr. | UNINA-9910786763903321 |
| Oxford, England ; ; New York : , : Oxford University Press, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Opioid therapy in the 21st century / / edited by Howard S. Smith
| Opioid therapy in the 21st century / / edited by Howard S. Smith |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Oxford, England ; ; New York : , : Oxford University Press, , 2013 |
| Descrizione fisica | 1 online resource (307 pages) : illustrations |
| Disciplina | 615/.7822 |
| Collana | Oxford American Pain Library |
| Soggetto topico |
Pain - drug therapy
Pain - Chemotherapy Opioids - Therapeutic use |
| ISBN | 0-19-023675-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction to opioids / Howard S. Smith -- Overview of opioid-related terminology / Kenneth C. Jackson II and Howard S. Smith -- Diagnosis and assessment of pain / Charles E. Argoff and Andrew Dubin -- Opioid pharmacology / Mellar P. Davis and Howard S. Smith -- Optimizing pharmacologic outcomes : drug selection / Kenneth C. Jackson II & Howard S. Smith -- Optimizing pharmacologic outcomes : route selection / Howard S. Smith -- Optimizing pharmacologic outcomes : assessing and managing opioid side effects / Howard S. Smith, Gary McCleane, and Gary Thompson -- Opioid-induced hyperalgesia / Lucy Chen and Jianren Mao -- Optimizing pharmacologic outcomes : principles of opioid rotation / Howard S. Smith and Bill H. McCarberg -- Optimizing pharmacologic outcomes : individualization of therapy / Howard S. Smith -- Opioid therapy for cancer pain / Mellar P. Davis and Howard S. Smith -- Evidence for the use of long-term opioid therapy in persistent noncancer pain / Howard S. Smith, Gary McCleane and Gary Thompson -- Pre-opioid prescribing period / Howard S. Smith -- Identifying patients at risk for pain medication misuse / Lynn R. Webster and Howard S. Smith -- Potential documentation tools in long-term opioid therapy / Howard S. Smith and Kenneth L. Kirsh -- Managing the risk of abuse, addiction, and diversion / Howard S. Smith -- Special populations : pediatric / Amy Mitchell and Howard S. Smith -- Special populations : geriatric / Gary McCleane -- Special populations : palliative care / Lida Nabati and Janet Abrahm -- Patients with a history of substance abuse / Kenneth L. Kirsh and Steven D. Passik. |
| Record Nr. | UNINA-9910812642403321 |
| Oxford, England ; ; New York : , : Oxford University Press, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pharmacologie de la douleur [[ressource électronique] /] / sous la direction de Pierre Beaulieu
| Pharmacologie de la douleur [[ressource électronique] /] / sous la direction de Pierre Beaulieu |
| Pubbl/distr/stampa | [Montréal, Que.], : Presses de l'Université de Montréal, 2005 |
| Descrizione fisica | 1 online resource (607 p.) |
| Disciplina | 616/.0472 |
| Altri autori (Persone) | BeaulieuPierre <1958-> |
| Soggetto topico |
Douleur - Chimiothérapie
Clinical pharmacology Analgesics Douleur Douleur - Traitement Pharmacologie clinique Analgésiques Pain - Chemotherapy Pain Pain - Treatment |
| Soggetto genere / forma | Electronic books. |
| ISBN | 2-7606-2436-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | fre |
| Record Nr. | UNINA-9910478890703321 |
| [Montréal, Que.], : Presses de l'Université de Montréal, 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pharmacologie de la douleur / / sous la direction de Pierre Beaulieu
| Pharmacologie de la douleur / / sous la direction de Pierre Beaulieu |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | [Montréal, Que.], : Presses de l'Université de Montréal, 2005 |
| Descrizione fisica | 1 online resource (607 p.) |
| Disciplina | 616/.0472 |
| Altri autori (Persone) | BeaulieuPierre <1958-> |
| Soggetto topico |
Douleur - Chimiothérapie
Clinical pharmacology Analgesics Douleur Douleur - Traitement Pharmacologie clinique Analgésiques Pain - Chemotherapy Pain Pain - Treatment |
| ISBN |
2-7606-2981-3
2-7606-2436-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | fre |
| Nota di contenuto | Intro -- TABLE DES MATIÈRES -- PREMIÈRE PARTIE: ASPECTS FONDAMENTAUX -- CHAPITRE 1 Neurophysiologie de la douleur -- CHAPITRE 2 Pharmacologie des opioïdes -- CHAPITRE 3 Pharmacologie des anti-inflammatoires non stéroïdiens -- CHAPITRE 4 Système nerveux autonome et douleur -- CHAPITRE 5 Pharmacologie des cannabinoïdes -- CHAPITRE 6 Pharmacologie des anesthésiques locaux -- CHAPITRE 7 Pharmacologie des antidépresseurs et des anticonvulsivants -- CHAPITRE 8 Nouvelles approches pharmacologiques dans le traitement de la douleur -- CHAPITRE 9 Les modèles animaux de douleur -- DEUXIÈME PARTIE: APPROCHE CLINIQUE -- CHAPITRE 10 Évaluation de la douleur -- CHAPITRE 11 L'analgésie placebo -- CHAPITRE 12 Approche et traitement de la douleur aiguë -- CHAPITRE 13 Approche et traitement de la douleur neuropathique -- CHAPITRE 14 Approche et traitement de la douleur cancéreuse -- CHAPITRE 15 Particularités pharmacologiques de la douleur en obstétrique -- CHAPITRE 16 Particularités pharmacologiques de la prise en charge de la douleur aiguë chez l'enfant -- CHAPITRE 17 Particularités pharmacologiques de la douleur chez le patient âgé -- CHAPITRE 18 Bioéthique et douleur -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- K -- L -- M -- N -- O -- P -- R -- S -- T -- V -- W. |
| Record Nr. | UNINA-9910838399103321 |
| [Montréal, Que.], : Presses de l'Université de Montréal, 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
