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Chemistry and Biochemistry of Oxygen Therapeutics [[electronic resource] ] : From Transfusion to Artificial Blood
| Chemistry and Biochemistry of Oxygen Therapeutics [[electronic resource] ] : From Transfusion to Artificial Blood |
| Autore | Mozzarelli Andrea |
| Pubbl/distr/stampa | Hoboken, : Wiley, 2011 |
| Descrizione fisica | 1 online resource (476 p.) |
| Disciplina |
615.8/36
615.836 |
| Altri autori (Persone) | BettatiStefano |
| Soggetto topico |
Hemoglobins - therapeutic use
Hemoglobins -- therapeutic use Nitric oxide - Physiological effect Nitric oxide -- Physiological effect Oxigen - Physiological effect Oxigen -- Physiological effect Oxygen - blood Oxygen -- blood Oxygen Consumption Oxygen Inhalation Therapy - methods Oxygen Inhalation Therapy -- methods Oxygen therapy SCIENCE / Life Sciences / Biochemistry Oxygen therapy - Physiological effect Oxygen - Physiological effect Nitric oxide Metabolic Phenomena Respiratory Therapy Investigative Techniques Body Fluids Globins Chalcogens Blood Proteins Gases Therapeutics Fluids and Secretions Elements Hemeproteins Inorganic Chemicals Proteins Amino Acids, Peptides, and Proteins Anatomy Oxygen Blood Hemoglobins Methods Oxygen Inhalation Therapy Health & Biological Sciences Pharmacy, Therapeutics, & Pharmacology |
| ISBN |
1-283-17785-4
9786613177858 1-119-97542-5 1-119-97543-3 |
| Classificazione | SCI007000 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Chemistry and Biochemistry of Oxygen Therapeutics; Contents; List of Contributors; Preface; 1. Introduction; References; Part I. Oxygen: Chemistry, Biochemistry, Physiology and Toxicity; 2. Hemoglobin Reactivity and Regulation; 2.1 Introduction; 2.2 Oxygen Loading and Transport; 2.3 NO Reactivity with Hb; 2.4 Hb Oxidation; 2.5 Nitrite Reactivity with Hb; 2.6 Amino-acid Determinants of Hb Reactivity: Natural and Engineered Hbs; 2.6.1 Modulation of Oxygen Affinity and Cooperativity; 2.6.2 NO Reactivity and Oxidation; 2.7 Conclusion; Acknowledgments; References
3. The Major Physiological Control Mechanisms of Blood Flow and Oxygen Delivery3.1 Introduction; 3.2 Autoregulation of Blood Flow to Changes in Perfusion Pressure; 3.3 Metabolic Regulation of Blood Flow; 3.4 O2 Transport; 3.5 O2 Delivery; 3.6 Endothelial Control of Vasomotor Tone; 3.7 Effect of Cell-free Hb on Endothelial Function; 3.8 Hypoxic Hypoxia; 3.9 Carbon Monoxide Hypoxia; 3.10 Anemia; 3.11 Conclusion; References; 4. The Main Players: Hemoglobin and Myoglobin; Nitric Oxide and Oxygen; 4.1 Introduction; 4.2 Role of Mammalian Mb in O2 Homeostasis 4.3 WhatLfs Missing in the Mb Knockout Mouse4.4 Evolutionary Origins of Mb and the Nitrogen Cycle; 4.5 Human Hb: Evolved Sensor of pO2 and Redox; 4.6 Broad Reactivity and Influence of NO: Lessons from the Microcosm Hb; 4.7 Some Fish Demonstrate a Fundamental "Need" for Hb-dependent NO Cycling, as in Humans; 4.8 Reactions of NO with Hb that Preserve NO Bioactivity; 4.9 Mammalian RBC/Hb.NO Interactions; 4.10 A Mutant Mouse Challenges the SNO-Hb Hypothesis, but does not Overthrow it; 4.11 Signaling by Hb-derived SNO: A Metabolically Responsive, Regulated Pathway 4.12 Signaling by Hb-derived SNO: Pathway Complexity Revealed by Multiple Defects in Disease States4.13 Therapeutic Implications of the Hb.NO Signaling System; 4.14 HBOCs, NO, and SNO; 4.15 Other Gaseous Hb Ligands of Potential Therapeutic Significance; 4.16 NO-related Enzymatic Activities of Hb: Reconciling Nitrite Reductase and SNO Synthase Functions; 4.17 Measuring Biologically Relevant Hb.NO Adducts; 4.18 Conclusion; Acknowledgments; References; 5. The Role of Reactive Oxygen and Nitrogen Species in Ischemia/Reperfusion Injury; 5.1 Introduction 5.2 Redox System and Free Radicals in Biological Systems5.3 Pathophysiology of Ischemia/Reperfusion Injury; 5.3.1 Cell Death; 5.3.2 The Inflammatory Response; 5.4 Protection Against I/R Injury; 5.4.1 Ischemic Pre- and Post-conditioning; 5.4.2 Pharmacological Conditioning; 5.4.2.1 The Protective Role of ROS and Antioxidants; 5.4.2.2 The Protective Role of NO; 5.4.2.3 NO-based Therapies for I/R Injury; 5.5 Conclusion; Acknowledgments; References; Part II. Medical Needs for Oxygen Supply; 6. Acute Traumatic Hemorrhage and Anemia; 6.1 Introduction; 6.2 Blood Transfusion in Trauma 6.2.1 Massive Transfusion |
| Record Nr. | UNINA-9910139631203321 |
Mozzarelli Andrea
|
||
| Hoboken, : Wiley, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Chemistry and biochemistry of oxygen therapeutics : from transfusion to artificial blood / / edited by Andrea Mozzarelli and Stefano Bettati
| Chemistry and biochemistry of oxygen therapeutics : from transfusion to artificial blood / / edited by Andrea Mozzarelli and Stefano Bettati |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Chichester [England] ; ; Hoboken, N.J., : Wiley, 2011 |
| Descrizione fisica | 1 online resource (476 p.) |
| Disciplina |
615.8/36
615.836 |
| Altri autori (Persone) |
MozzarelliAndrea
BettatiStefano |
| Soggetto topico |
Oxygen therapy
Oxigen - Physiological effect Nitric oxide - Physiological effect |
| ISBN |
1-283-17785-4
9786613177858 1-119-97542-5 1-119-97543-3 |
| Classificazione | SCI007000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | pt. 1. Oxygen : chemistry, biochemistry, physiology and toxicity -- pt. 2. Medical needs for oxygen supply -- pt. 3. "Old" and new strategies for oxygen supply. |
| Record Nr. | UNINA-9910806996303321 |
| Chichester [England] ; ; Hoboken, N.J., : Wiley, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Evite confusiones con el oxígeno medicinal [[electronic resource] ] : No olvide mirar antes de conectar!
| Evite confusiones con el oxígeno medicinal [[electronic resource] ] : No olvide mirar antes de conectar! |
| Pubbl/distr/stampa | [Rockville, Md.] : , : U.S. Dept. of Health and Human Services, Food and Drug Administration, , [2009?] |
| Descrizione fisica | 1 sheet : digital, PDF file |
| Soggetto topico |
Oxygen therapy
Oxygen - Equipment and supplies - Safety measures |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | spa |
| Altri titoli varianti | Evite confusiones con el oxígeno medicinal |
| Record Nr. | UNINA-9910698180203321 |
| [Rockville, Md.] : , : U.S. Dept. of Health and Human Services, Food and Drug Administration, , [2009?] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Guidance for hospitals, nursing homes and other health care facilities [[electronic resource]]
| Guidance for hospitals, nursing homes and other health care facilities [[electronic resource]] |
| Pubbl/distr/stampa | Rockville, MD : , : U.S. Dept. of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, , [2001] |
| Descrizione fisica | 1 online resource (4 pages) |
| Soggetto topico |
Low temperature engineering
Oxygen therapy Nursing homes - Safety measures - Government policy - United States Hospitals - Safety measures - Government policy - United States |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910699115203321 |
| Rockville, MD : , : U.S. Dept. of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, , [2001] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Hemoglobin-based oxygen carriers as red cell substitutes and oxygen therapeutics / / Hae Won Kim, A. Gerson Greenburg, editors
| Hemoglobin-based oxygen carriers as red cell substitutes and oxygen therapeutics / / Hae Won Kim, A. Gerson Greenburg, editors |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Heidelberg [Germany] : , : Springer, , 2013 |
| Descrizione fisica | 1 online resource (xxiii, 746 pages) : illustrations (some color) |
| Disciplina |
611.01816
615.19 615.399 616.15 |
| Collana | Gale eBooks |
| Soggetto topico |
Oxygen - Physiological transport
Oxygen therapy Blood substitutes |
| ISBN | 3-642-40717-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Brief historical account of HBOC development -- Physiology of respiration -- Oxygen transport to tissues -- Pathophysiology of acute anemia -- Global blood safety and need for safe blood supply -- Blood transfusion and its limitations -- Scientific basis and design of HBOCs -- HBOCs: a regulatory perspective -- Current HBOC products in development -- Clinical indications and clinical trials of HBOCs -- HBOCs and adverse events observed in clinical trials -- HBOC-mediated vasoactivity and hypertension -- HBOC and oxygen and nitrogen radical mediated toxicity -- HBOCs and clinical laboratory interference -- Animal models for HBOC studies -- New emerging Technologies for universal RBCs -- Future prospects. |
| Record Nr. | UNINA-9910437798003321 |
| Heidelberg [Germany] : , : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Medical gases : production, applications and safety / / Hartwig Müller
| Medical gases : production, applications and safety / / Hartwig Müller |
| Autore | Müller Hartwig |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2015 |
| Descrizione fisica | 1 online resource (185 p.) |
| Disciplina | 615.836 |
| Soggetto topico |
Oxygen therapy
Gases - Therapeutic use |
| ISBN |
3-527-67603-1
3-527-67601-5 3-527-67604-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; Contents; Preface; General Remarks; Chapter 1 Medicinal Gases - Manufacturing; 1.1 Where Do the Gases Come from?; 1.1.1 Gases Obtained from Air: Oxygen, Nitrogen, Argon, Xenon; 1.1.1.1 Oxygen; 1.1.1.2 Nitrogen; 1.1.1.3 Argon; 1.1.1.4 Xenon; 1.1.2 Gases Separated from Other Sources: Helium, Carbon Monoxide, Methane; 1.1.2.1 Helium; 1.1.2.2 Carbon Monoxide; 1.1.2.3 Methane; 1.1.3 Gases from Chemical Synthesis: Carbon Dioxide, Nitric Oxide, Nitrous Oxide; 1.1.3.1 Carbon Dioxide; 1.1.3.2 Nitric Oxide; 1.1.3.3 Nitrous Oxide; 1.1.4 Gas Mixtures for Inhalation
1.1.4.1 Reconstituted (Synthetic) Air1.1.4.2 Compressed Medical Air; 1.1.4.3 Nitrous Oxide 50 vol% in Oxygen; 1.1.4.4 Nitric Oxide Approximately 1000 ppm in Nitrogen; 1.1.4.5 Mixtures with the General Composition Carbon Monoxide, Helium in Synthetic Air (Carbon Monoxide Ranging between 0.2 and 0.3 vol%, Helium between 8 and 18 vol%); 1.1.4.6 Carbogen (5 vol% Carbon Dioxide in Oxygen); 1.1.5 Gas Mixtures for Reference - Calibration Gas Mixtures; Chapter 2 Pressure Vessels and Their Accessories; 2.1 Transportable Pressure Receptacles: Pressure Cylinders; 2.1.1 Seamless Steel Cylinders 2.1.2 Seamless Aluminum Cylinders2.1.2.1 Specifics of Aluminum Cylinders; 2.1.3 Welded Steel Vessels; 2.1.4 Lightweight Wrapped Steel or Aluminum Cylinders; 2.1.5 Pharmaceutical View on Cylinders as Containment for Drugs; 2.1.5.1 European Pharmacopoeia View on Cylinders as Containment for Drugs; 2.1.5.2 Inner and Outer Surfaces of Cylinders; 2.1.6 Accessories for Cylinders: Valves; 2.1.6.1 Accessories for Valves: Gaskets; 2.1.6.2 Valves with Integrated Residual Pressure/Nonreturn Cartridge (NRV/PRV); 2.1.6.3 Integrated Valves 2.2 Non-transportable Pressure Receptacles: Stationary (Pressure) Tanks for Cryogenic Liquids2.2.1 Safety Measures on Stationary Tanks; 2.2.2 European Pharmacopoeia View on Cryo-Tanks as Containment for Drugs; 2.2.3 Inner and Outer Surfaces of Cryo-Tanks; 2.2.4 Accessories for Cryo-Containers; 2.2.5 Choice of the Good Location for Tanks; 2.3 Medicinal Gas Pipeline Systems (MGPS); 2.3.1 Elements of a Medical Gas Pipeline System (MGPS); 2.3.1.1 Gas Terminal Units (Wall Sockets); 2.3.2 Tests and Checks before Going Onstream; 2.3.3 Operation of a Central Medical Supply System 2.3.4 Maintenance and Service, Pharmaceutical ViewChapter 3 Analytical Methods for Gases (as Described in Ph. Eur.); 3.1 Sampling; 3.1.1 Permanent Gases; 3.1.2 Gases Liquefied under Pressure; 3.1.3 Cryogenic Gases; 3.2 Gas Analytical Methods; 3.2.1 Infrared (IR-) Spectrometry; 3.2.1.1 Calibration; 3.2.2 Gas Chromatography (Lit); 3.2.2.1 Calibration; 3.2.3 Chemiluminescence; 3.2.3.1 Calibration; 3.2.4 Paramagnetic Measurement; 3.2.4.1 Calibration; 3.2.5 Moisture Measurement; 3.2.5.1 Calibration; 3.2.6 Fluorescence Analysis; 3.2.6.1 Calibration; 3.2.7 Test Tubes Chapter 4 Monographs for Gases in the European and National Pharmacopoeias |
| Record Nr. | UNINA-9910131511103321 |
|
Müller Hartwig
|
||
| Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Medical gases : production, applications and safety / / Hartwig Müller
| Medical gases : production, applications and safety / / Hartwig Müller |
| Autore | Müller Hartwig |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2015 |
| Descrizione fisica | 1 online resource (185 p.) |
| Disciplina | 615.836 |
| Soggetto topico |
Oxygen therapy
Gases - Therapeutic use |
| ISBN |
3-527-67603-1
3-527-67601-5 3-527-67604-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; Contents; Preface; General Remarks; Chapter 1 Medicinal Gases - Manufacturing; 1.1 Where Do the Gases Come from?; 1.1.1 Gases Obtained from Air: Oxygen, Nitrogen, Argon, Xenon; 1.1.1.1 Oxygen; 1.1.1.2 Nitrogen; 1.1.1.3 Argon; 1.1.1.4 Xenon; 1.1.2 Gases Separated from Other Sources: Helium, Carbon Monoxide, Methane; 1.1.2.1 Helium; 1.1.2.2 Carbon Monoxide; 1.1.2.3 Methane; 1.1.3 Gases from Chemical Synthesis: Carbon Dioxide, Nitric Oxide, Nitrous Oxide; 1.1.3.1 Carbon Dioxide; 1.1.3.2 Nitric Oxide; 1.1.3.3 Nitrous Oxide; 1.1.4 Gas Mixtures for Inhalation
1.1.4.1 Reconstituted (Synthetic) Air1.1.4.2 Compressed Medical Air; 1.1.4.3 Nitrous Oxide 50 vol% in Oxygen; 1.1.4.4 Nitric Oxide Approximately 1000 ppm in Nitrogen; 1.1.4.5 Mixtures with the General Composition Carbon Monoxide, Helium in Synthetic Air (Carbon Monoxide Ranging between 0.2 and 0.3 vol%, Helium between 8 and 18 vol%); 1.1.4.6 Carbogen (5 vol% Carbon Dioxide in Oxygen); 1.1.5 Gas Mixtures for Reference - Calibration Gas Mixtures; Chapter 2 Pressure Vessels and Their Accessories; 2.1 Transportable Pressure Receptacles: Pressure Cylinders; 2.1.1 Seamless Steel Cylinders 2.1.2 Seamless Aluminum Cylinders2.1.2.1 Specifics of Aluminum Cylinders; 2.1.3 Welded Steel Vessels; 2.1.4 Lightweight Wrapped Steel or Aluminum Cylinders; 2.1.5 Pharmaceutical View on Cylinders as Containment for Drugs; 2.1.5.1 European Pharmacopoeia View on Cylinders as Containment for Drugs; 2.1.5.2 Inner and Outer Surfaces of Cylinders; 2.1.6 Accessories for Cylinders: Valves; 2.1.6.1 Accessories for Valves: Gaskets; 2.1.6.2 Valves with Integrated Residual Pressure/Nonreturn Cartridge (NRV/PRV); 2.1.6.3 Integrated Valves 2.2 Non-transportable Pressure Receptacles: Stationary (Pressure) Tanks for Cryogenic Liquids2.2.1 Safety Measures on Stationary Tanks; 2.2.2 European Pharmacopoeia View on Cryo-Tanks as Containment for Drugs; 2.2.3 Inner and Outer Surfaces of Cryo-Tanks; 2.2.4 Accessories for Cryo-Containers; 2.2.5 Choice of the Good Location for Tanks; 2.3 Medicinal Gas Pipeline Systems (MGPS); 2.3.1 Elements of a Medical Gas Pipeline System (MGPS); 2.3.1.1 Gas Terminal Units (Wall Sockets); 2.3.2 Tests and Checks before Going Onstream; 2.3.3 Operation of a Central Medical Supply System 2.3.4 Maintenance and Service, Pharmaceutical ViewChapter 3 Analytical Methods for Gases (as Described in Ph. Eur.); 3.1 Sampling; 3.1.1 Permanent Gases; 3.1.2 Gases Liquefied under Pressure; 3.1.3 Cryogenic Gases; 3.2 Gas Analytical Methods; 3.2.1 Infrared (IR-) Spectrometry; 3.2.1.1 Calibration; 3.2.2 Gas Chromatography (Lit); 3.2.2.1 Calibration; 3.2.3 Chemiluminescence; 3.2.3.1 Calibration; 3.2.4 Paramagnetic Measurement; 3.2.4.1 Calibration; 3.2.5 Moisture Measurement; 3.2.5.1 Calibration; 3.2.6 Fluorescence Analysis; 3.2.6.1 Calibration; 3.2.7 Test Tubes Chapter 4 Monographs for Gases in the European and National Pharmacopoeias |
| Record Nr. | UNINA-9910813769903321 |
|
Müller Hartwig
|
||
| Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Numerische Untersuchungen des Stofftransports und der Signalentstehung in LambdasondenNumerische Untersuchungen des Stofftransports und der Signalentstehung in Lambdasonden / / vorgelegt von Stephan Goll
| Numerische Untersuchungen des Stofftransports und der Signalentstehung in LambdasondenNumerische Untersuchungen des Stofftransports und der Signalentstehung in Lambdasonden / / vorgelegt von Stephan Goll |
| Autore | Goll Stephan |
| Pubbl/distr/stampa | Berlin : , : Logos Verlag, , 2010 |
| Descrizione fisica | 1 online resource (xx, 112 pages) : illustrations |
| Disciplina | 615.836 |
| Soggetto topico | Oxygen therapy |
| Soggetto genere / forma | Electronic books. |
| ISBN | 3-8325-9763-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Record Nr. | UNINA-9910467448303321 |
|
Goll Stephan
|
||
| Berlin : , : Logos Verlag, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Numerische Untersuchungen des Stofftransports und der Signalentstehung in LambdasondenNumerische Untersuchungen des Stofftransports und der Signalentstehung in Lambdasonden / / vorgelegt von Stephan Goll
| Numerische Untersuchungen des Stofftransports und der Signalentstehung in LambdasondenNumerische Untersuchungen des Stofftransports und der Signalentstehung in Lambdasonden / / vorgelegt von Stephan Goll |
| Autore | Goll Stephan |
| Pubbl/distr/stampa | Berlin : , : Logos Verlag, , 2010 |
| Descrizione fisica | 1 online resource (xx, 112 pages) : illustrations |
| Disciplina | 615.836 |
| Soggetto topico | Oxygen therapy |
| ISBN | 3-8325-9763-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Record Nr. | UNINA-9910795215303321 |
|
Goll Stephan
|
||
| Berlin : , : Logos Verlag, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Numerische Untersuchungen des Stofftransports und der Signalentstehung in LambdasondenNumerische Untersuchungen des Stofftransports und der Signalentstehung in Lambdasonden / / vorgelegt von Stephan Goll
| Numerische Untersuchungen des Stofftransports und der Signalentstehung in LambdasondenNumerische Untersuchungen des Stofftransports und der Signalentstehung in Lambdasonden / / vorgelegt von Stephan Goll |
| Autore | Goll Stephan |
| Pubbl/distr/stampa | Berlin : , : Logos Verlag, , 2010 |
| Descrizione fisica | 1 online resource (xx, 112 pages) : illustrations |
| Disciplina | 615.836 |
| Soggetto topico | Oxygen therapy |
| ISBN | 3-8325-9763-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Record Nr. | UNINA-9910821834703321 |
|
Goll Stephan
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||
| Berlin : , : Logos Verlag, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Oxygen therapy
(13)
- Oxygen Inhalation Therapy (3)
- Diving (2)
- Duiken (2)
- Gases - Therapeutic use (2)