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Biblioteca

MARC Lista (tabellare)
Biology of Bladder Cancer : From Molecular Insights to Clinical Strategies / / edited by Margaret A. Knowles, Lars Dyrskjøt
Biology of Bladder Cancer : From Molecular Insights to Clinical Strategies / / edited by Margaret A. Knowles, Lars Dyrskjøt
Autore Knowles Margaret A
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (946 pages)
Disciplina 571.978
616.994
Altri autori (Persone) DyrskjøtLars
Soggetto topico Cancer
Oncology
Oncogenes
Tumor markers
Cancer - Treatment
Cancer Biology
Cancers
Tumour Biomarkers
Cancer Therapy
ISBN 9783031685057
3031685059
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I. Fundamentals of Bladder Cancer -- Chapter 1. Epidemiology of Bladder Cancer -- Chapter 2. Genetic Predisposition to Bladder Cancer -- Chapter 3. Human Urothelium -- Chapter 4. Bladder Cancer Pathology -- Chapter 5. Overview of Standard Therapy of Non Muscle-Invasive Bladder Cancer -- Chapter 6. Overview of Standard Therapy of Muscle-Invasive Bladder Cancer -- Part II. Molecular Genetics and Oncogenesis in Bladder Cancer -- Chapter 7. From Normalcy to Neoplasia: Mutational Events during Bladder Tumor Evolution -- Chapter 8. Cell Cycle Regulators as Oncogenic Drivers in Bladder Cancer -- Chapter 9. DNA Repair Pathway Alterations in Bladder Cancer -- Chapter 10. DNA Methylation and Chromatin Regulators in Bladder Cancer -- Part III. Pathogenesis and Microenvironment Dynamics in Bladder Cancer -- Chapter 11. Molecular Pathogenesis: Field Cancerization and Clonal Evolution in Urothelial Cancer Initiation and Progression -- Chapter 12. The Bladder Tumor Microenvironment -- Part IV. Molecular and Histological Subtypes of Bladder Cancer -- Chapter 13. Molecular Subtypes of Non-Muscle-Invasive Bladder Cancer -- Chapter 14. Molecular Subtypes of Muscle-Invasive Bladder Cancer -- Chapter 15. Molecular Features of Divergent Differentiation and Histological Subtypes in Bladder Cancer -- Part V. Experimental Models of Bladder Cancer -- Chapter 16. The Emerging Landscape of Mouse Bladder Cancer Models -- Chapter 17. In Vitro Bladder Cancer Models -- Part VI. Biomarkers for Diagnosis and Treatment of Bladder Cancer -- Chapter 18. Urine Biomarkers for Bladder Cancer Diagnosis and Screening -- Chapter 19. Blood-Based Biomarkers for Bladder Cancer Diagnosis and Prognosis -- Chapter 20. Mechanisms and Biomarkers of Response to BCG and Chemotherapy in Bladder Cancer -- Part VII. Therapeutic Application based on Molecular Insights -- Chapter 21. New Treatment Approaches in Non-Muscle-Invasive Bladder Cancer -- Chapter 22. New Treatment Approaches in Muscle-Invasive Bladder Cancer -- Chapter 23. Targeting the Immune Checkpoint in Bladder Cancer -- Part VIII. Future Directions in Bladder Cancer Research -- Chapter 24. Future Directions in Bladder Cancer Research and Clinical Implications.
Record Nr. UNINA-9910946349603321
Knowles Margaret A  
Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Genetic analysis of tumour suppression [[electronic resource]]
Genetic analysis of tumour suppression [[electronic resource]]
Pubbl/distr/stampa Chichester ; ; New York, : Wiley, 1989
Descrizione fisica 1 online resource (270 p.)
Disciplina 616.99
616.994042
Altri autori (Persone) BockGregory
MarshJoan
Collana Ciba Foundation symposium
Soggetto topico Tumors - Genetic aspects
Gene expression
Oncogenes
Soggetto genere / forma Electronic books.
ISBN 1-282-34759-4
9786612347597
0-470-51375-6
0-470-51376-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto GENETIC ANALYSIS OF TUMOUR SUPPRESSION; Contents; Participants; Introduction; Epidemiology of genetically determined cancer; Transgenic mice and host cell mutants resistant to transformation as model systems for identifying multiple components in oncogenesis; Reversion of tumorigenicity in an EBV-converted Burkitt's lymphoma line; Lymphoid neoplasia and the control of haemopoietic differentiation; General discussion I; Loss of genetic information in cancer; General discussion II; The molecular basis of retinoblastomas; General discussion Ill
Proviral position effects: possible probes for genes that suppress transcriptionGeneral discussion IV; Flat revertants of EJ human bladder carcinoma cells show two different mechanisms of reversion; A genetic basis for tumour suppression; Molecular basis for the regulation of cell fate by the lethal (2) giant larvae tumour suppressor gene of Drosophila melanogaster; Suppression of genetic melanoma in the fish Xiphophorus; The biology of tumour suppression; General discussion V; Cell differentiation and tumour suppression; General discussion VI; Final discussion; Index of contributors
Subject index
Record Nr. UNINA-9910144560503321
Chichester ; ; New York, : Wiley, 1989
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Genetic analysis of tumour suppression [[electronic resource]]
Genetic analysis of tumour suppression [[electronic resource]]
Pubbl/distr/stampa Chichester ; ; New York, : Wiley, 1989
Descrizione fisica 1 online resource (270 p.)
Disciplina 616.99
616.994042
Altri autori (Persone) BockGregory
MarshJoan
Collana Ciba Foundation symposium
Soggetto topico Tumors - Genetic aspects
Gene expression
Oncogenes
ISBN 1-282-34759-4
9786612347597
0-470-51375-6
0-470-51376-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto GENETIC ANALYSIS OF TUMOUR SUPPRESSION; Contents; Participants; Introduction; Epidemiology of genetically determined cancer; Transgenic mice and host cell mutants resistant to transformation as model systems for identifying multiple components in oncogenesis; Reversion of tumorigenicity in an EBV-converted Burkitt's lymphoma line; Lymphoid neoplasia and the control of haemopoietic differentiation; General discussion I; Loss of genetic information in cancer; General discussion II; The molecular basis of retinoblastomas; General discussion Ill
Proviral position effects: possible probes for genes that suppress transcriptionGeneral discussion IV; Flat revertants of EJ human bladder carcinoma cells show two different mechanisms of reversion; A genetic basis for tumour suppression; Molecular basis for the regulation of cell fate by the lethal (2) giant larvae tumour suppressor gene of Drosophila melanogaster; Suppression of genetic melanoma in the fish Xiphophorus; The biology of tumour suppression; General discussion V; Cell differentiation and tumour suppression; General discussion VI; Final discussion; Index of contributors
Subject index
Record Nr. UNINA-9910830198903321
Chichester ; ; New York, : Wiley, 1989
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Genetic analysis of tumour suppression
Genetic analysis of tumour suppression
Pubbl/distr/stampa Chichester ; ; New York, : Wiley, 1989
Descrizione fisica 1 online resource (270 p.)
Disciplina 616.99
616.994042
Altri autori (Persone) BockGregory
MarshJoan
Collana Ciba Foundation symposium
Soggetto topico Tumors - Genetic aspects
Gene expression
Oncogenes
ISBN 9786612347597
9781282347595
1282347594
9780470513750
0470513756
9780470513767
0470513764
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto GENETIC ANALYSIS OF TUMOUR SUPPRESSION; Contents; Participants; Introduction; Epidemiology of genetically determined cancer; Transgenic mice and host cell mutants resistant to transformation as model systems for identifying multiple components in oncogenesis; Reversion of tumorigenicity in an EBV-converted Burkitt's lymphoma line; Lymphoid neoplasia and the control of haemopoietic differentiation; General discussion I; Loss of genetic information in cancer; General discussion II; The molecular basis of retinoblastomas; General discussion Ill
Proviral position effects: possible probes for genes that suppress transcriptionGeneral discussion IV; Flat revertants of EJ human bladder carcinoma cells show two different mechanisms of reversion; A genetic basis for tumour suppression; Molecular basis for the regulation of cell fate by the lethal (2) giant larvae tumour suppressor gene of Drosophila melanogaster; Suppression of genetic melanoma in the fish Xiphophorus; The biology of tumour suppression; General discussion V; Cell differentiation and tumour suppression; General discussion VI; Final discussion; Index of contributors
Subject index
Record Nr. UNINA-9911019225203321
Chichester ; ; New York, : Wiley, 1989
Materiale a stampa
Lo trovi qui: Univ. Federico II
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How to win the Nobel Prize [[electronic resource] ] : an unexpected life in science. / / J. Michael Bishop
How to win the Nobel Prize [[electronic resource] ] : an unexpected life in science. / / J. Michael Bishop
Autore Bishop J. Michael <1936->
Edizione [1st Harvard University Press pbk. ed.]
Pubbl/distr/stampa Cambridge, MA ; ; London, : Harvard University Press, 2004
Descrizione fisica xiii, 271 p. : ill
Disciplina 610.92
Collana The Jerusalem-Harvard lectures
Soggetto topico Medical scientists - United States
Oncogenes
Nobel Prizes
Soggetto genere / forma Electronic books.
ISBN 0-674-02097-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Frontmatter -- Contents -- List of Illustrations -- Preface -- 1. The Phone Call -- 2. Accidental Scientist -- 3. People and Pestilence -- 4. Opening the Black Box of Cancer -- 5. Paradoxical Strife -- Notes -- Credits -- Index
Record Nr. UNINA-9910455133003321
Bishop J. Michael <1936->  
Cambridge, MA ; ; London, : Harvard University Press, 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
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How to win the Nobel Prize [[electronic resource] ] : an unexpected life in science. / / J. Michael Bishop
How to win the Nobel Prize [[electronic resource] ] : an unexpected life in science. / / J. Michael Bishop
Autore Bishop J. Michael <1936->
Edizione [1st Harvard University Press pbk. ed.]
Pubbl/distr/stampa Cambridge, MA ; ; London, : Harvard University Press, 2004
Descrizione fisica xiii, 271 p. : ill
Disciplina 610.92
Collana The Jerusalem-Harvard lectures
Soggetto topico Medical scientists - United States
Oncogenes
Nobel Prizes
ISBN 0-674-02097-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Frontmatter -- Contents -- List of Illustrations -- Preface -- 1. The Phone Call -- 2. Accidental Scientist -- 3. People and Pestilence -- 4. Opening the Black Box of Cancer -- 5. Paradoxical Strife -- Notes -- Credits -- Index
Record Nr. UNINA-9910778455503321
Bishop J. Michael <1936->  
Cambridge, MA ; ; London, : Harvard University Press, 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
How to win the Nobel Prize : an unexpected life in science. / / J. Michael Bishop
How to win the Nobel Prize : an unexpected life in science. / / J. Michael Bishop
Autore Bishop J. Michael <1936->
Edizione [1st Harvard University Press pbk. ed.]
Pubbl/distr/stampa Cambridge, MA ; ; London, : Harvard University Press, 2004
Descrizione fisica xiii, 271 p. : ill
Disciplina 610.92
Collana The Jerusalem-Harvard lectures
Soggetto topico Medical scientists - United States
Oncogenes
Nobel Prizes
ISBN 9780674020979
0674020979
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Frontmatter -- Contents -- List of Illustrations -- Preface -- 1. The Phone Call -- 2. Accidental Scientist -- 3. People and Pestilence -- 4. Opening the Black Box of Cancer -- 5. Paradoxical Strife -- Notes -- Credits -- Index
Record Nr. UNINA-9910969413803321
Bishop J. Michael <1936->  
Cambridge, MA ; ; London, : Harvard University Press, 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Molecules Engineered Against Oncogenic Proteins and Cancer : Discovery, Design, and Development
Molecules Engineered Against Oncogenic Proteins and Cancer : Discovery, Design, and Development
Autore Corey E. J
Edizione [1st ed.]
Pubbl/distr/stampa Newark : , : John Wiley & Sons, Incorporated, , 2023
Descrizione fisica 1 online resource (391 pages)
Altri autori (Persone) WuYong-Jin
Soggetto topico Protein kinases - Inhibitors
Oncogenes
ISBN 9781394207145
139420714X
9781394207091
1394207093
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover -- Title Page -- Copyright -- Contents -- Preface -- Chapter 1. Introduction -- 1.1 Types of Protein Kinases -- 1.2 Protein Kinase Domains -- 1.3 ATP-Binding Site -- 1.4 Types of Kinase Inhibitors -- 1.5 Brief History of Small-molecule kinase Inhibitors -- 1.6 Peak 12-Month Sales for Leading Kinase Inhibitors -- 1.7 Approved Kinase Inhibitors -- Chapter 2. BCR-ABL Inhibitors -- 2.1 Imatinib* -- 2.2 Nilotinib* -- 2.3 Dasatinib* -- 2.4 Bosutinib* -- 2.5 Ponatinib* -- 2.6 Olvermbatinib** -- 2.7 Asciminib* -- Chapter 3. BTK Inhibitors -- 3.1 Ibrutinib* -- 3.2 Acalabrutinib* -- 3.3 Zanubrutinib* -- 3.4 Tirabrutinib** -- 3.5 Orelabrutinib** -- Chapter 4. EGFR/HER Family Inhibitors -- 4.1 Gefitinib* -- 4.2 Erlotinib * -- 4.3 Icotinib** -- 4.4 Afatinib* -- 4.5 Dacomitinib* -- 4.6 Osimertinib* -- 4.7 Mobocertinib* -- 4.8 Lapatinib* -- 4.9 Tucatinib* -- 4.10 Neratinib* -- Chapter 5. VEGFR/Multikinase Inhibitors -- 5.1 Sorafenib* -- 5.2 Regorafenib* -- 5.3 Sunitinib* -- 5.4 Pazopanib* -- 5.5 Axitinib* -- 5.6 Nintedanib* -- 5.7 Apatinib** -- 5.8 Lenvatinib* -- 5.9 Tovozanib* -- Chapter 6. CDK4/6 Inhibitors -- 6.1 Palbociclib* -- 6.2 Ribociclib* -- 6.3 Abemaciclib* -- 6.4 Trilaciclib* -- Chapter 7. JAK Inhibitors -- 7.1 Tofacitinib* -- 7.2 Baricitinib* -- 7.3 Peficitinib** -- 7.4 Upadacitinib* -- 7.5 Delgocitinib** -- 7.6 Filgotinib** -- 7.7 Abrocitinib* -- 7.8 Ruxolitinib* -- 7.9 Fedratinib* -- 7.10 Pacritinib* -- 7.11 Ritlecitinib# -- 7.12 Brepocitinib# -- 7.13 Ropsacitinib# -- Chapter 8. Allosteric TYK2 Inhibitors -- 8.1 Deucravacitinib* -- Chapter 9. ALK/multikinase Inhibitors -- 9.1 Crizotinib* -- 9.2 Ceritinib* -- 9.3 Alectinib* -- 9.4 Brigatinib* -- 9.5 Lorlatinib* -- Chapter 10. BRAF/Multikinase Inhibitors -- 10.1 Vemurafenib* -- 10.2 Dabrafenib* -- 10.3 Encorafenib* -- Chapter 11. MEK Inhibitors -- 11.1 Trametinib* -- 11.2 Cobimetinib*.
11.3 Binimetinib* -- 11.4 Selumetinib* -- Chapter 12. RET/Multikinase Inhibitors -- 12.1 Vandetanib* -- 12.2 Cabozantinib* -- 12.3 Selpercatinib* -- 12.4 Pralsetinib* -- Chapter 13. FGFR Inhibitors -- 13.1 Erdafitinib* -- 13.2 Pemigatinib* -- 13.3 Infigratinib* -- 13.4 Futibatinib* -- Chapter 14. PI3K Inhibitors -- 14.1 Alpelisib* -- 14.2 Idelalisib* -- 14.3 Duvelisib* -- 14.4 Umbralisib* -- 14.5 Copanlisib* -- Chapter 15. TRK/Multikinase Inhibitors -- 15.1 Larotrectinib* -- 15.2 Entrectinib* -- 15.3 Repotrectinib# -- Chapter 16. MET Inhibitors -- 16.1 Capmatinib* -- 16.2 Tepotinib* -- Chapter 17. KIT/PDGFR/Multkinase Inhibitors -- 17.1 Avapritinib* -- 17.2 Ripretinib* -- Chapter 18. FLT3 Inhibitors -- 18.1 Midostaurin* -- 18.2 Gilteritinib* -- Chapter 19. mTOR Inhibitors -- 19.1 Sirolimus* and Analogs -- Chapter 20. Other Kinase Inhibitors -- 20.1 Netarsudil* -- 20.2 Belumosudil* -- 20.3 Fostamatinib* -- 20.4 Pexidartinib* -- Chapter 21. KRAS Inhibitors -- 21.1 Sotorasib* -- 21.2 Adagrasib* -- 21.3 JDQ443# -- Chapter 22. An Overview of the Discovery Process for Medically Useful Inhibitors of Oncogenic Protein Kinases -- 22.1 High-quality Leads -- 22.2 Integrating Substructures from Different High Quality Leads or Established Inhibitors -- 22.3 Variation of Hinge-binding Nucleus -- 22.4 Macrocyclization -- 22.5 Fragment-based Approach -- 22.6 Covalent Inhibitors -- 22.7 Strategic Structural Modification of Prior Drugs -- 22.8 Exploiting Specific Kinase Pocket to Optimize Selectivity -- 22.9 Solvent-exposed Appendages to Enhance Solubility and PK Properties -- Chapter 23. Targeted Molecular Anticancer Therapies - Successes and Challenges -- 23.1 The Beginning -- 23.2 Further Developments -- 23.3 Biomarker-driven Drug Development -- 23.4 Mitigation of Drug Resistance -- 23.5 Miscellaneous Approaches -- 23.6 Discovery Chemistry.
Appendix 1. First FDA Approvals by Year -- Appendix 2. Kinase/KRAS Inhibitors in Development -- Appendix 3. Visualization of Differentially Expressed Kinases in Cancer -- Appendix 4. M & -- A Transactions Driven by Oncology-focused Kinase and KRAS Inhibitors -- Appendix 5. Alphabetic List of Oncogenic Protein Inhibitors -- EULA.
Record Nr. UNINA-9911020083103321
Corey E. J  
Newark : , : John Wiley & Sons, Incorporated, , 2023
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Onco
Onco
Pubbl/distr/stampa Basel, Switzerland : , : MDPI
Descrizione fisica 1 online resource
Disciplina 610
Soggetto topico Oncogenes
Cancer - Treatment
ISSN 2673-7523
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNINA-9910647286603321
Basel, Switzerland : , : MDPI
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Oncogene
Oncogene
Pubbl/distr/stampa [New York], : Stockton Press
Disciplina 616.994042
Soggetto topico Oncogenes
Soggetto genere / forma Periodical
Periodicals.
ISSN 1476-5594
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNISA-996518461603316
[New York], : Stockton Press
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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