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COX-2 inhibitor research [[electronic resource] /] / Maynard J. Howardell, editor
COX-2 inhibitor research [[electronic resource] /] / Maynard J. Howardell, editor
Pubbl/distr/stampa New York, : Nova Science Publishers, c2006
Descrizione fisica 1 online resource (263 p.)
Disciplina 615/.7
Altri autori (Persone) HowardellMaynard J
Soggetto topico Nonsteroidal anti-inflammatory agents
Arthritis - Chemotherapy
Anti-inflammatory agents
Soggetto genere / forma Electronic books.
ISBN 1-61668-114-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cyclooxygenase-2 inhibitor and gastric cancer / Yumin Li, Raaj K. Praseedom, and Andrew Butler et al. -- Prevention and chemoprevention of gastric cancer : dietary habits, Helicobacter pylori and COX-2 inhibitors / Gerardo Nardone and Alba Rocco -- Cyclooxygenases in cancer / Daniela Fodera ... et al. -- Nephrotoxicity of nonsteroidal anti-inflammatory drugs : focus on selective cyclooxygenase-2 (COX-2) inhibitors / Steven G. Coca and Mark A. Perazella -- Are COX-2 inhibitors active on intracellular oxidative processes? A study on in vitro and cellular models / Ange Mouithys-Mickalad et al. -- Theoretical mechanism studies on dual inhibition of human cyclooxygenase-2 and 5-lipoxygenase by diaryl-pyrrolizine derivatives / R. Pouplana, C. Perez, and J. Ruiz --
NSAIDs in animal models of Alzheimer's disease / N.G. Giovannini, C. Scali, and A. Bellucci -- Relevance of COX-2 inhibitors in Alzheimer's disease / Amita Quadros, Laila Abdullah, and Nikunj Patel et al. -- COX.1-COX.2 simultaneous inhibitory mechanism in gastric injury and COX.2-COX.3 in small intestine injury / Laudanno Oscar -- Effects of COX-2 inhibitors on brain diseases / Takako Takemiya -- Cyclooxygenase-2 overexpression and the chemopreventive and therapeutic uses of cyclooxygenase inhibitors in lung cancer / Zhongxing Liao et al. -- Safety monitoring of celecoxib and rofecoxib in the New Zealand intensive medicines monitoring programme / David Coutler et al.
Record Nr. UNINA-9910458171203321
New York, : Nova Science Publishers, c2006
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
COX-2 inhibitor research [[electronic resource] /] / Maynard J. Howardell, editor
COX-2 inhibitor research [[electronic resource] /] / Maynard J. Howardell, editor
Pubbl/distr/stampa New York, : Nova Science Publishers, c2006
Descrizione fisica 1 online resource (263 p.)
Disciplina 615/.7
Altri autori (Persone) HowardellMaynard J
Soggetto topico Nonsteroidal anti-inflammatory agents
Arthritis - Chemotherapy
Anti-inflammatory agents
ISBN 1-61668-114-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cyclooxygenase-2 inhibitor and gastric cancer / Yumin Li, Raaj K. Praseedom, and Andrew Butler et al. -- Prevention and chemoprevention of gastric cancer : dietary habits, Helicobacter pylori and COX-2 inhibitors / Gerardo Nardone and Alba Rocco -- Cyclooxygenases in cancer / Daniela Fodera ... et al. -- Nephrotoxicity of nonsteroidal anti-inflammatory drugs : focus on selective cyclooxygenase-2 (COX-2) inhibitors / Steven G. Coca and Mark A. Perazella -- Are COX-2 inhibitors active on intracellular oxidative processes? A study on in vitro and cellular models / Ange Mouithys-Mickalad et al. -- Theoretical mechanism studies on dual inhibition of human cyclooxygenase-2 and 5-lipoxygenase by diaryl-pyrrolizine derivatives / R. Pouplana, C. Perez, and J. Ruiz --
NSAIDs in animal models of Alzheimer's disease / N.G. Giovannini, C. Scali, and A. Bellucci -- Relevance of COX-2 inhibitors in Alzheimer's disease / Amita Quadros, Laila Abdullah, and Nikunj Patel et al. -- COX.1-COX.2 simultaneous inhibitory mechanism in gastric injury and COX.2-COX.3 in small intestine injury / Laudanno Oscar -- Effects of COX-2 inhibitors on brain diseases / Takako Takemiya -- Cyclooxygenase-2 overexpression and the chemopreventive and therapeutic uses of cyclooxygenase inhibitors in lung cancer / Zhongxing Liao et al. -- Safety monitoring of celecoxib and rofecoxib in the New Zealand intensive medicines monitoring programme / David Coutler et al.
Record Nr. UNINA-9910791133703321
New York, : Nova Science Publishers, c2006
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
COX-2 inhibitor research [[electronic resource] /] / Maynard J. Howardell, editor
COX-2 inhibitor research [[electronic resource] /] / Maynard J. Howardell, editor
Edizione [1st ed.]
Pubbl/distr/stampa New York, : Nova Science Publishers, c2006
Descrizione fisica 1 online resource (263 p.)
Disciplina 615/.7
Altri autori (Persone) HowardellMaynard J
Soggetto topico Nonsteroidal anti-inflammatory agents
Arthritis - Chemotherapy
Anti-inflammatory agents
ISBN 1-61668-114-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cyclooxygenase-2 inhibitor and gastric cancer / Yumin Li, Raaj K. Praseedom, and Andrew Butler et al. -- Prevention and chemoprevention of gastric cancer : dietary habits, Helicobacter pylori and COX-2 inhibitors / Gerardo Nardone and Alba Rocco -- Cyclooxygenases in cancer / Daniela Fodera ... et al. -- Nephrotoxicity of nonsteroidal anti-inflammatory drugs : focus on selective cyclooxygenase-2 (COX-2) inhibitors / Steven G. Coca and Mark A. Perazella -- Are COX-2 inhibitors active on intracellular oxidative processes? A study on in vitro and cellular models / Ange Mouithys-Mickalad et al. -- Theoretical mechanism studies on dual inhibition of human cyclooxygenase-2 and 5-lipoxygenase by diaryl-pyrrolizine derivatives / R. Pouplana, C. Perez, and J. Ruiz --
NSAIDs in animal models of Alzheimer's disease / N.G. Giovannini, C. Scali, and A. Bellucci -- Relevance of COX-2 inhibitors in Alzheimer's disease / Amita Quadros, Laila Abdullah, and Nikunj Patel et al. -- COX.1-COX.2 simultaneous inhibitory mechanism in gastric injury and COX.2-COX.3 in small intestine injury / Laudanno Oscar -- Effects of COX-2 inhibitors on brain diseases / Takako Takemiya -- Cyclooxygenase-2 overexpression and the chemopreventive and therapeutic uses of cyclooxygenase inhibitors in lung cancer / Zhongxing Liao et al. -- Safety monitoring of celecoxib and rofecoxib in the New Zealand intensive medicines monitoring programme / David Coutler et al.
Record Nr. UNINA-9910817984103321
New York, : Nova Science Publishers, c2006
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs : Formulation Challenges and Potential Benefits
Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs : Formulation Challenges and Potential Benefits
Autore Čalija Bojan
Pubbl/distr/stampa San Diego : , : Elsevier Science & Technology, , 2017
Descrizione fisica 1 online resource (286 pages)
Disciplina 615.1
615.7
Altri autori (Persone) ČalijaBojan
Soggetto topico Nonsteroidal anti-inflammatory agents
Drug carriers (Pharmacy)
ISBN 0-12-804080-7
0-12-804017-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover -- Title page -- Copyright page -- Contents -- List of Contributors -- Editor Biography -- Preface -- Chapter 1 - Clinical Uses of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Potential Benefits of NSAIDs Modified-Releas... -- 1.1 - Nonsteroidal Anti-inflammatory drugs -- 1.1.1 - Classification and Mechanism of Action -- 1.1.1.1 - Classification -- 1.1.1.2 - COX Isoforms and Their Roles -- 1.1.1.3 - NSAIDs Mechanism of Action -- 1.1.2 - Pharmacokinetic Properties -- 1.1.2.1 - Biopharmaceutical/Pharmacokinetic Considerations of Topically Administered NSAIDs -- 1.1.3 - Therapeutic Actions and Uses -- 1.1.3.1 - Musculoskeletal Disorders -- 1.1.3.1.1 - Osteoarthritis -- 1.1.3.1.2 - Rheumatoid Arthritis -- 1.1.3.2 - Mild to Moderate Pain -- 1.1.3.3 - Fever -- 1.1.3.4 - Cardioprotection (Aspirin) -- 1.1.4 - Adverse Effects -- 1.1.4.1 - Gastrointestinal Side Effects -- 1.1.4.2 - Cardiovascular Side Effects -- 1.1.4.3 - Renal Side Effects -- 1.1.5 - Interactions -- 1.2 - Potential benefits of NSAIDs modified-release preparations -- 1.2.1 - Oral NSAIDs Modified-Release Preparations -- 1.2.2 - Topical NSAIDs Modified-Release Preparations -- 1.3 - Conclusions -- Acknowledgment -- References -- Chapter 2 - Polymeric Microparticles and Inorganic Micro/Nanoparticulate Drug Carriers: An Overview and Pharmaceutical Appl... -- 2.1 - Introduction -- 2.2 - Polymeric microparticles as drug carriers -- 2.2.1 - Microencapsulation Techniques -- 2.2.1.1 - Chemical Microencapsulation Techniques -- 2.2.1.2 - Physicochemical Microencapsulation Techniques -- 2.2.1.3 - Physicomechanical Microencapsulation Techniques -- 2.2.2 - Characteristics of Polymeric Microparticles -- 2.2.3 - Pharmaceutical Application of Polymeric Microparticles -- 2.3 - Porous inorganic materials as drug carriers -- 2.3.1 - Characteristics of Porous Inorganic Materials Used in Drug Delivery.
2.3.2 - Structured Porous Inorganic Materials Used in Drug Delivery: An Overview -- 2.3.3 - Pharmaceutical Application of Structured Porous Inorganic Materials -- 2.4 - Conclusions -- Acknowledgment -- References -- Chapter 3 - Microemulsions and Nanoemulsions as Carriers for Delivery of NSAIDs -- 3.1 - Introduction -- 3.2 - Microemulsions and nanoemulsions as drug-delivery carriers -- 3.3 - Design and characterization of biocompatible microemulsion/nanoemulsion drug-delivery systems -- 3.4 - Evaluation of potential of microemulsion/nanoemulsion systems for oral delivery of NSAIDs -- 3.5 - Conclusions -- References -- Chapter 4 - Diversity and Functionality of Excipients for Micro/Nanosized Drug Carriers -- 4.1 - Introduction -- 4.2 - Functionality and performance of excipients: definitions and compendial status -- 4.3 - Biodegradable polymeric materials in micro/nanoparticles -- 4.3.1 - Definition, Structure, and Characteristics of Polymers -- 4.3.2 - Classification of Biodegradable Encapsulating Polymers -- 4.3.3 - The Selection of Encapsulating Polymer -- 4.3.4 - Functionality of Biodegradable Polymers as Excipients for Micro/Nanosized Drug Carriers -- 4.4 - Natural and synthetic silica-based materials as micro/nanosized drug carriers -- 4.4.1 - Structure and Functional Characteristics of Silica-Based Materials -- 4.4.2 - Functionalization of Natural and Synthetic Silica-Based Materials as Micro/Nanosized Drug Carriers -- 4.5 - Natural surfactants in micro/nanoemulsions -- 4.5.1 - Surfactant Role in Micro/Nanoemulsions -- 4.5.2 - Definition, Structure, and Classification of Natural Surfactants -- 4.5.3 - Functionality of Natural Surfactants as Excipients in Micro/Nanoemulsions -- 4.5.3.1 - Lecithin -- 4.5.3.2 - Sucrose Esters -- 4.5.3.3 - Alkyl Polyglucosides -- 4.6 - Conclusions -- Acknowledgment -- References.
Chapter 5 - Influence of Polycation Functional Properties on Polyanion Micro/Nanoparticles for NSAIDs Reinforced Via Polyel... -- 5.1 - Introduction -- 5.2 - Chitosans: an overview on properties, functionality, and safety -- 5.2.1 - Source and Structural Characteristics of Chitosans -- 5.2.2 - Physicochemical Properties and Reactivity of Chitosans -- 5.2.3 - Safety and Regulatory Status of Chitosans -- 5.3 - Alginate-chitosan micro/nanoparticles as drug carriers -- 5.3.1 - Ca-Alginate Hydrogels as Drug Carriers: Characteristics and Disadvantages -- 5.3.2 - Chitosans as Cationic Modifiers of Ca-Alginate Micro/Nanoparticles -- 5.3.3 - Preparation Methods of Alginate-Chitosan Micro/Nanoparticles -- 5.4 - Influence of chitosans functional properties on characteristics of alginate-chitosan micro/nanoparticles loaded with ... -- 5.5 - Conclusions -- Acknowledgment -- References -- Chapter 6 - PLA-Based Nanoparticulate Drug Carriers as a Percutaneous Delivery System for Ketoprofen -- 6.1 - Introduction -- 6.2 - Ketoprofen-loaded PLA nanoparticles: preparation and characterization aspects -- 6.3 - In vitro evaluation of ketoprofen-loaded PLA nanoparticles as colloidal systems for percutaneous drug delivery -- 6.4 - Conclusions -- References -- Chapter 7 - Natural Surfactants-Based Micro/Nanoemulsion Systems for NSAIDs-Practical Formulation Approach, Physicochemical... -- 7.1 - Introduction -- 7.2 - Sucrose ester-based microemulsions: phase behavior, physicochemical characterization, and imaging properties -- 7.2.1 - Phase Behavior of Sucrose Ester-Based Systems -- 7.2.1.1 - Effect of the Tail Length of SEs -- 7.2.1.2 - Effect of Monoester Content of SEs -- 7.2.1.3 - Effect of Cosurfactant/Cosolvent Choice and Surfactant/Cosurfactant Weight Ratio -- 7.2.1.4 - Effect of HLB Values of SE.
7.2.2 - Physicochemical Properties of Sucrose Ester-Based Microemulsions -- 7.2.2.1 - Electrical Conductivity -- 7.2.2.2 - Viscosity -- 7.2.2.3 - Thermal Behavior -- 7.2.3 - Imaging Properties of Sucrose Ester-Based Microemulsions -- 7.2.3.1 - Cryo-Transmission Electron Microscopy -- 7.2.3.2 - Freeze Fracture-Transmission Electron Microscopy -- 7.2.3.3 - Atomic Force Microscopy -- 7.3 - Lecithin- and sucrose ester-based nanoemulsions-formulation design aspects, physicochemical characterization, and sta... -- 7.3.1 - The Selection of Emulsifiers-Lecithin and Sucrose Esters -- 7.3.2 - The Selection of Oil and Aqueous Phase -- 7.3.3 - Nanoemulsion Formulation and Preparation-QbD Approach -- 7.3.4 - Physicochemical Characterization and Stability Testing -- 7.3.4.1 - Droplet Size Analysis and Microstructure Evaluation -- 7.3.4.2 - Zeta Potential and pH Value Determination -- 7.3.4.3 - Viscosity Measurements -- 7.3.4.4 - Assessment of Drug Chemical Stability -- 7.4 - NSAID-loaded micro/nanoemulsions: in vitro/ex vivo/in vivo dermal and transdermal availability -- 7.5 - Conclusions -- Acknowledgment -- References -- Chapter 8 - Natural and Modified Silica-Based Materials as Carriers for NSAIDs -- 8.1 - Introduction -- 8.2 - Natural and modified aluminosilicates: characterization and application in drug delivery -- 8.2.1 - Physicochemical and Functionality-Related Characteristics of Natural and Modified Aluminosilicates: An Overview -- 8.2.2 - Natural and Modified Aluminosilicates: Application as Carriers for NSAIDs -- 8.3 - Modified biosilica structures from diatomite frustules: preparation, physicochemical characterization, and application -- 8.3.1 - Diatomite Processing and Its Physicochemical Characteristics -- 8.3.2 - Applications of Natural and Modified Diatomites in Drug Delivery -- 8.4 - Conclusions -- Acknowledgment -- References -- Index.
Back cover.
Record Nr. UNINA-9910583323303321
Čalija Bojan  
San Diego : , : Elsevier Science & Technology, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Non-steroidal anti-inflammatory drugs in water : emerging contaminants and ecological impact / / volume editor: Leobardo Manuel Gómez-Oliván ; with contributions by L. Aranda-Lara [and fifty three others]
Non-steroidal anti-inflammatory drugs in water : emerging contaminants and ecological impact / / volume editor: Leobardo Manuel Gómez-Oliván ; with contributions by L. Aranda-Lara [and fifty three others]
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2020]
Descrizione fisica 1 online resource (XIII, 338 p. 1 illus.)
Disciplina 615.7
Collana The Handbook of Environmental Chemistry
Soggetto topico Water - Pollution
Environmental chemistry
Nonsteroidal anti-inflammatory agents
ISBN 3-030-56294-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction and historical findings that focused Non-steroidal Anti-inflammatory Drugs as emerging pollutant -- Overview of non-steroidal anti-inflammatory drugs as emerging contaminants -- Worldwide occurrence, detection and fate of Nonsteroidal Anti-inflammatory Drugs in water -- Quantification of Nonsteroidal Anti-inflammatory Drugs in water -- DNA alterations and cellular damage induced by non-steroidal anti-inflammatories on different species of fish -- Teratogenesis and embryotoxicity induced by Non-Steroidal Anti-inflammatory drugs in aquatic organisms -- Ecotoxicological effects of the drug paracetamol: a critical review of past ecotoxicity assessments and future perspectives -- Adverse effects induced by Non-Steroidal Anti-Inflammatory Drugs on freshwater invertebrates -- Ibuprofen and Diclofenac, effects on freshwater and marine aquatic organisms. Are they at risk? -- Toxicity assessment of acetylsalicylic acid to a freshwater fish Cyprinus carpio: hematological, biochemical, enzymological and antioxidant responses -- Contemporary methods for removal of non-steroidal anti-inflammatory drugs in water reclamations -- Photo-Fenton treatment of a pharmaceutical industrial effluent under safe pH conditions -- Use of membrane for removal of Non-steroidal anti-inflammatory drugs -- Nanotechnologies for removal of Non-steroidal Anti-inflammatory Drug from wastewater -- Biological technologies used for the removal of Non-steroidal Anti-inflammatory Drugs -- Risk evaluation and legal framework of the nonsteroidal anti-inflammatory drugs around the world -- Conclusions.
Record Nr. UNINA-9910424640303321
Cham, Switzerland : , : Springer, , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Nonsteroidal anti-inflammatory drugs (NSAIDs) : common uses, risks and effectiveness / / Diane Flores, editor
Nonsteroidal anti-inflammatory drugs (NSAIDs) : common uses, risks and effectiveness / / Diane Flores, editor
Pubbl/distr/stampa New York : , : Nova Biomedical, , [2017]
Descrizione fisica 1 online resource (211 pages) : illustrations
Disciplina 615.7
Collana Pharmacology - research, safety testing and regulation
Soggetto topico Nonsteroidal anti-inflammatory agents
ISBN 1-5361-0910-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910164041403321
New York : , : Nova Biomedical, , [2017]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Trends in the use and expenditures for COX-2 inhibitors and traditional nonsteroidal anti-inflammatory drugs, 1997-2003 [[electronic resource] /] / Jessica Banthin and Marc Zodet
Trends in the use and expenditures for COX-2 inhibitors and traditional nonsteroidal anti-inflammatory drugs, 1997-2003 [[electronic resource] /] / Jessica Banthin and Marc Zodet
Autore Banthin Jessica S
Pubbl/distr/stampa [Rockville, Md.] : , : Medical Expenditure Panel Survey, Agency for Healthcare Research and Quality, , [2006]
Descrizione fisica 6 unnumbered pages : digital, PDF file
Collana Statistical brief
Soggetto topico Nonsteroidal anti-inflammatory agents
Cyclooxygenase 2 - Inhibitors
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910697548103321
Banthin Jessica S  
[Rockville, Md.] : , : Medical Expenditure Panel Survey, Agency for Healthcare Research and Quality, , [2006]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui