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Disease markers in exhaled breath [[electronic resource] ] : basic mechanisms and clinical applications / / edited by Nandor Marczin and Magdi H. Yacoub
| Disease markers in exhaled breath [[electronic resource] ] : basic mechanisms and clinical applications / / edited by Nandor Marczin and Magdi H. Yacoub |
| Pubbl/distr/stampa | Amsterdam ; ; Washington, DC, : IOS Press, c2002 |
| Descrizione fisica | 1 online resource (443 p.) |
| Disciplina | 616.2/4075 |
| Altri autori (Persone) |
MarczinNándor <1962->
YacoubMagdi |
| Collana | NATO science series. Series I, Life and behavioural sciences |
| Soggetto topico |
Lungs - Diseases - Diagnosis
Breath tests Biochemical markers Nitric oxide - Pathophysiology Carbon monoxide - Pathophysiology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
600-00-0402-8
1-280-50559-1 9786610505593 1-60129-419-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover""; ""Title page""; ""Preface""; ""Sponsors""; ""List of Participants""; ""Contents""; ""Part I. Introduction to Disease Markers in Exhaled Breath""; ""Section 1. Nitric Oxide""; ""Regulation of Nitric Oxide Synthases in the Lung""; ""Nitric Oxide Production in the Lung and its Regulation by Oxygen""; ""S-Nitrosothiols in Respiratory Biology""; ""Inhibitors of Nitric Oxide Synthase: Experimental Findings and Clinical Implications""; ""Inhaled NO as a Replacement Therapy""; ""Physiology of Exhaled Nitric Oxide""; ""The ""Vascular"" Origins of Exhaled Nitric Oxide""
""Exhaled NO originates in Airway Epithelium""""NO is Generated via NOS Enzymes""; ""Technical Aspects of Exhaled NO: Investigator Point of View""; ""Technical Aspects of Exhaled Nitric Oxide: Aerocrine Point of View""; ""Section 2. Carbon Monoxide""; ""Cytoprotection by Heme Oxygenase / CO in the Lung""; ""Role of Heme Oxygenase in Airway Smooth Muscle Contractility""; ""Exhaled Carbon Monoxide is Produced in the Lungs""; ""Exhaled Carbon Monoxide is Delivered from Systemic Sources""; ""Kinetics of Carbon Monoxide Accumulation in Exhaled Breath"" ""ETCOc: An Indicator of Hemolysis in Neonatal Hyperbilirubinemia""""Section 3. Volatile Organic Compounds (VOCs)""; ""Volatile Organic Compounds as Exposure Markers""; ""Volatile Organic Compounds as Markers in Normal and Diseased States""; ""Section 4. The ""Living State""""; ""The Living State: Intimate Insights through Personal Discoveries""; ""Part II. Asthma""; ""Biology of Asthma""; ""Transcriptional Regulation of Airway Inflammation""; ""Molecular Mechanisms of Steroid Actions""; ""Nitric Oxide Reactions in the Asthmatic Airway"" ""Regulation of pH in the Human Airway: Mechanisms and Monitoring""""Markers in Exhaled Air and Condensate to Monitor Treatment in Asthma""; ""Extended NO Analysis Applied to Patients with Known Altered Values of Exhaled NO""; ""Exhaled Nitric Oxide and Atopy""; ""Bradykinin and Exhaled Nitric Oxide in Asthma""; ""Exhaled NO is an Optimal Marker of Severity and Responsiveness to Therapy in Asthma""; ""Superoxide-NO Interactions in Paranasal Sinus Inflammatory Diseases""; ""Part III. Chronic Lung Diseases""; ""Biology, Diagnosis and Management of COPD"" ""Disease Markers in COPD: Exhaled Breath vs. Exhaled Condensate""""The Biology of Cystic Fibrosis""; ""Exhaled Markers in Cystic Fibrosis""; ""Lung Cancer Screening by Breath Analysis""; ""Nitric Oxide and Rheumatic Diseases""; ""Nitric Oxide in Hepatopulmonary Syndrome""; ""Pathological Changes in the Airways Epithelium of Liquidators of the Chernobyl Catastrophe""; ""Part IV. Transplantation""; ""Heme Oxygenase-1 and/or Carbon Monoxide can Promote Organ Graft Survival""; ""Mechanisms of and Clinical Efforts to Minimise Perioperative Lung Injury"" ""Condensate Inflammatory Markers in Lung Transplantation"" |
| Record Nr. | UNINA-9910455584203321 |
| Amsterdam ; ; Washington, DC, : IOS Press, c2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Disease markers in exhaled breath [[electronic resource] ] : basic mechanisms and clinical applications / / edited by Nandor Marczin and Magdi H. Yacoub
| Disease markers in exhaled breath [[electronic resource] ] : basic mechanisms and clinical applications / / edited by Nandor Marczin and Magdi H. Yacoub |
| Pubbl/distr/stampa | Amsterdam ; ; Washington, DC, : IOS Press, c2002 |
| Descrizione fisica | 1 online resource (443 p.) |
| Disciplina | 616.2/4075 |
| Altri autori (Persone) |
MarczinNándor <1962->
YacoubMagdi |
| Collana | NATO science series. Series I, Life and behavioural sciences |
| Soggetto topico |
Lungs - Diseases - Diagnosis
Breath tests Biochemical markers Nitric oxide - Pathophysiology Carbon monoxide - Pathophysiology |
| ISBN |
600-00-0402-8
1-280-50559-1 9786610505593 1-60129-419-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover""; ""Title page""; ""Preface""; ""Sponsors""; ""List of Participants""; ""Contents""; ""Part I. Introduction to Disease Markers in Exhaled Breath""; ""Section 1. Nitric Oxide""; ""Regulation of Nitric Oxide Synthases in the Lung""; ""Nitric Oxide Production in the Lung and its Regulation by Oxygen""; ""S-Nitrosothiols in Respiratory Biology""; ""Inhibitors of Nitric Oxide Synthase: Experimental Findings and Clinical Implications""; ""Inhaled NO as a Replacement Therapy""; ""Physiology of Exhaled Nitric Oxide""; ""The ""Vascular"" Origins of Exhaled Nitric Oxide""
""Exhaled NO originates in Airway Epithelium""""NO is Generated via NOS Enzymes""; ""Technical Aspects of Exhaled NO: Investigator Point of View""; ""Technical Aspects of Exhaled Nitric Oxide: Aerocrine Point of View""; ""Section 2. Carbon Monoxide""; ""Cytoprotection by Heme Oxygenase / CO in the Lung""; ""Role of Heme Oxygenase in Airway Smooth Muscle Contractility""; ""Exhaled Carbon Monoxide is Produced in the Lungs""; ""Exhaled Carbon Monoxide is Delivered from Systemic Sources""; ""Kinetics of Carbon Monoxide Accumulation in Exhaled Breath"" ""ETCOc: An Indicator of Hemolysis in Neonatal Hyperbilirubinemia""""Section 3. Volatile Organic Compounds (VOCs)""; ""Volatile Organic Compounds as Exposure Markers""; ""Volatile Organic Compounds as Markers in Normal and Diseased States""; ""Section 4. The ""Living State""""; ""The Living State: Intimate Insights through Personal Discoveries""; ""Part II. Asthma""; ""Biology of Asthma""; ""Transcriptional Regulation of Airway Inflammation""; ""Molecular Mechanisms of Steroid Actions""; ""Nitric Oxide Reactions in the Asthmatic Airway"" ""Regulation of pH in the Human Airway: Mechanisms and Monitoring""""Markers in Exhaled Air and Condensate to Monitor Treatment in Asthma""; ""Extended NO Analysis Applied to Patients with Known Altered Values of Exhaled NO""; ""Exhaled Nitric Oxide and Atopy""; ""Bradykinin and Exhaled Nitric Oxide in Asthma""; ""Exhaled NO is an Optimal Marker of Severity and Responsiveness to Therapy in Asthma""; ""Superoxide-NO Interactions in Paranasal Sinus Inflammatory Diseases""; ""Part III. Chronic Lung Diseases""; ""Biology, Diagnosis and Management of COPD"" ""Disease Markers in COPD: Exhaled Breath vs. Exhaled Condensate""""The Biology of Cystic Fibrosis""; ""Exhaled Markers in Cystic Fibrosis""; ""Lung Cancer Screening by Breath Analysis""; ""Nitric Oxide and Rheumatic Diseases""; ""Nitric Oxide in Hepatopulmonary Syndrome""; ""Pathological Changes in the Airways Epithelium of Liquidators of the Chernobyl Catastrophe""; ""Part IV. Transplantation""; ""Heme Oxygenase-1 and/or Carbon Monoxide can Promote Organ Graft Survival""; ""Mechanisms of and Clinical Efforts to Minimise Perioperative Lung Injury"" ""Condensate Inflammatory Markers in Lung Transplantation"" |
| Record Nr. | UNINA-9910780246803321 |
| Amsterdam ; ; Washington, DC, : IOS Press, c2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Disease markers in exhaled breath : basic mechanisms and clinical applications / / edited by Nandor Marczin and Magdi H. Yacoub
| Disease markers in exhaled breath : basic mechanisms and clinical applications / / edited by Nandor Marczin and Magdi H. Yacoub |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Washington, DC, : IOS Press, c2002 |
| Descrizione fisica | 1 online resource (443 p.) |
| Disciplina | 616.2/4075 |
| Altri autori (Persone) |
MarczinNandor <1962->
YacoubMagdi |
| Collana | NATO science series. Series I, Life and behavioural sciences |
| Soggetto topico |
Lungs - Diseases - Diagnosis
Breath tests Biochemical markers Nitric oxide - Pathophysiology Carbon monoxide - Pathophysiology |
| ISBN |
600-00-0402-8
1-280-50559-1 9786610505593 1-60129-419-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover""; ""Title page""; ""Preface""; ""Sponsors""; ""List of Participants""; ""Contents""; ""Part I. Introduction to Disease Markers in Exhaled Breath""; ""Section 1. Nitric Oxide""; ""Regulation of Nitric Oxide Synthases in the Lung""; ""Nitric Oxide Production in the Lung and its Regulation by Oxygen""; ""S-Nitrosothiols in Respiratory Biology""; ""Inhibitors of Nitric Oxide Synthase: Experimental Findings and Clinical Implications""; ""Inhaled NO as a Replacement Therapy""; ""Physiology of Exhaled Nitric Oxide""; ""The ""Vascular"" Origins of Exhaled Nitric Oxide""
""Exhaled NO originates in Airway Epithelium""""NO is Generated via NOS Enzymes""; ""Technical Aspects of Exhaled NO: Investigator Point of View""; ""Technical Aspects of Exhaled Nitric Oxide: Aerocrine Point of View""; ""Section 2. Carbon Monoxide""; ""Cytoprotection by Heme Oxygenase / CO in the Lung""; ""Role of Heme Oxygenase in Airway Smooth Muscle Contractility""; ""Exhaled Carbon Monoxide is Produced in the Lungs""; ""Exhaled Carbon Monoxide is Delivered from Systemic Sources""; ""Kinetics of Carbon Monoxide Accumulation in Exhaled Breath"" ""ETCOc: An Indicator of Hemolysis in Neonatal Hyperbilirubinemia""""Section 3. Volatile Organic Compounds (VOCs)""; ""Volatile Organic Compounds as Exposure Markers""; ""Volatile Organic Compounds as Markers in Normal and Diseased States""; ""Section 4. The ""Living State""""; ""The Living State: Intimate Insights through Personal Discoveries""; ""Part II. Asthma""; ""Biology of Asthma""; ""Transcriptional Regulation of Airway Inflammation""; ""Molecular Mechanisms of Steroid Actions""; ""Nitric Oxide Reactions in the Asthmatic Airway"" ""Regulation of pH in the Human Airway: Mechanisms and Monitoring""""Markers in Exhaled Air and Condensate to Monitor Treatment in Asthma""; ""Extended NO Analysis Applied to Patients with Known Altered Values of Exhaled NO""; ""Exhaled Nitric Oxide and Atopy""; ""Bradykinin and Exhaled Nitric Oxide in Asthma""; ""Exhaled NO is an Optimal Marker of Severity and Responsiveness to Therapy in Asthma""; ""Superoxide-NO Interactions in Paranasal Sinus Inflammatory Diseases""; ""Part III. Chronic Lung Diseases""; ""Biology, Diagnosis and Management of COPD"" ""Disease Markers in COPD: Exhaled Breath vs. Exhaled Condensate""""The Biology of Cystic Fibrosis""; ""Exhaled Markers in Cystic Fibrosis""; ""Lung Cancer Screening by Breath Analysis""; ""Nitric Oxide and Rheumatic Diseases""; ""Nitric Oxide in Hepatopulmonary Syndrome""; ""Pathological Changes in the Airways Epithelium of Liquidators of the Chernobyl Catastrophe""; ""Part IV. Transplantation""; ""Heme Oxygenase-1 and/or Carbon Monoxide can Promote Organ Graft Survival""; ""Mechanisms of and Clinical Efforts to Minimise Perioperative Lung Injury"" ""Condensate Inflammatory Markers in Lung Transplantation"" |
| Record Nr. | UNINA-9910808218503321 |
| Amsterdam ; ; Washington, DC, : IOS Press, c2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Free radicals, nitric oxide, and inflammation [[electronic resource] ] : molecular, biochemical, and clinical aspects / / edited by Aldo Tomasi, Tomris Ozben, and Vladimir P. Skulachev
| Free radicals, nitric oxide, and inflammation [[electronic resource] ] : molecular, biochemical, and clinical aspects / / edited by Aldo Tomasi, Tomris Ozben, and Vladimir P. Skulachev |
| Pubbl/distr/stampa | Amsterdam ; ; Washington, DC, : IOS Press, c2003 |
| Descrizione fisica | 1 online resource (264 p.) |
| Disciplina | 616.0473 |
| Altri autori (Persone) |
TomasiAldo
ÖzbenTomris SkulachevV. P (Vladimir Petrovich) |
| Collana | NATO science series. Series I, Life and behavioural sciences |
| Soggetto topico |
Inflammation - Pathophysiology
Free radicals (Chemistry) - Pathophysiology Nitric oxide - Pathophysiology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-60129-427-1
1-280-50545-1 600-00-0431-1 9786610505456 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover""; ""Title page""; ""Foreword""; ""Contents""; ""Alternative Functions of Mitochondria""; ""The Enzymatic Systems in the Regulation of Free Radical Lipid Peroxidation""; ""Flavanols and Procyanidins as Modulators of Oxidation in vitro and in vivo""; ""Estimation of Oxidative and Lipids Peroxidation DNA Adduct in Urine and DNA. Methodological Aspects and Application in Molecular Epidemiology""; ""Oxidative and Nitrosative Stress Mediated by Cyclosporine A in Endothelial Cells""; ""Early Signaling with Iron and Copper in Ischemic Preconditioning of the Heart""
""Multiple Mechanisms Regulating Endothelial Nitric Oxide Synthase""""Nitric Oxide. Its Generation, Reactions and Role in Physiology""; ""Redox-Regulated Glutathionylation of Transcription Factors: A Regulatory Mode for Gene Expression""; ""Sulphur-Containing Amino Acids, Glutathione and the Modulation of Inflammation""; ""Molecular Events of the Inflammation Process that are Affected by α-Tocopherol. Antioxidants and Gene Expression in the Process of Inflammation and Wound Repair""; ""Redox Regulation, Cytokine, and Nitric Oxide in Inflammation"" ""Non-Traditional Cardiovascular Disease Risk Factors and Arterial Inflammatory Response in End-Stage Renal Disease""""Significance of Reactive Oxygen Species for Neuronal Function""; ""Protein Aggregates and the Development of Neurodegenerative Diseases""; ""Inflammatory Response of the Brain Following Cerebral Ischemia""; ""Carnosine as Natural Antioxidant and Neuroprotector: Biological Functions and Possible Clinical Use""; ""Atherosclerosis as a Free Radical Pathology and Antioxidative Therapy of this Disease"" ""H[sub(2)]O[sub(2)] Sensors of Lungs and Blood Vessels and their Role in the Antioxidant Defense of the Body""""Oxidative Lung Injury""; ""Proper Design of Human Intervention Studies, Power Calculations""; ""Author Index""; ""A""; ""B""; ""C""; ""F""; ""G""; ""I""; ""K""; ""L""; ""M""; ""O""; ""P""; ""R""; ""S""; ""T""; ""V""; ""W""; ""Z"" |
| Record Nr. | UNINA-9910455979603321 |
| Amsterdam ; ; Washington, DC, : IOS Press, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Free radicals, nitric oxide, and inflammation : molecular, biochemical, and clinical aspects / / edited by Aldo Tomasi, Tomris Ozben, and Vladimir P. Skulachev
| Free radicals, nitric oxide, and inflammation : molecular, biochemical, and clinical aspects / / edited by Aldo Tomasi, Tomris Ozben, and Vladimir P. Skulachev |
| Pubbl/distr/stampa | Amsterdam ; ; Washington, DC : , : IOS Press, , 2003 |
| Descrizione fisica | 1 online resource (vii, 255 pages) : illustrations |
| Disciplina | 616.0473 |
| Altri autori (Persone) |
TomasiAldo
ÖzbenTomris SkulachevV. P (Vladimir Petrovich) |
| Collana | NATO science series. Series I, Life and behavioural sciences |
| Soggetto topico |
Inflammation - Pathophysiology
Free radicals (Chemistry) - Pathophysiology Nitric oxide - Pathophysiology |
| ISBN |
1-60129-427-1
1-280-50545-1 600-00-0431-1 9786610505456 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover""; ""Title page""; ""Foreword""; ""Contents""; ""Alternative Functions of Mitochondria""; ""The Enzymatic Systems in the Regulation of Free Radical Lipid Peroxidation""; ""Flavanols and Procyanidins as Modulators of Oxidation in vitro and in vivo""; ""Estimation of Oxidative and Lipids Peroxidation DNA Adduct in Urine and DNA. Methodological Aspects and Application in Molecular Epidemiology""; ""Oxidative and Nitrosative Stress Mediated by Cyclosporine A in Endothelial Cells""; ""Early Signaling with Iron and Copper in Ischemic Preconditioning of the Heart""
""Multiple Mechanisms Regulating Endothelial Nitric Oxide Synthase"" ""Nitric Oxide. Its Generation, Reactions and Role in Physiology""; ""Redox-Regulated Glutathionylation of Transcription Factors: A Regulatory Mode for Gene Expression""; ""Sulphur-Containing Amino Acids, Glutathione and the Modulation of Inflammation""; ""Molecular Events of the Inflammation Process that are Affected by α-Tocopherol. Antioxidants and Gene Expression in the Process of Inflammation and Wound Repair""; ""Redox Regulation, Cytokine, and Nitric Oxide in Inflammation"" ""Non-Traditional Cardiovascular Disease Risk Factors and Arterial Inflammatory Response in End-Stage Renal Disease"" ""Significance of Reactive Oxygen Species for Neuronal Function""; ""Protein Aggregates and the Development of Neurodegenerative Diseases""; ""Inflammatory Response of the Brain Following Cerebral Ischemia""; ""Carnosine as Natural Antioxidant and Neuroprotector: Biological Functions and Possible Clinical Use""; ""Atherosclerosis as a Free Radical Pathology and Antioxidative Therapy of this Disease"" ""H[sub(2)]O[sub(2)] Sensors of Lungs and Blood Vessels and their Role in the Antioxidant Defense of the Body"" ""Oxidative Lung Injury""; ""Proper Design of Human Intervention Studies, Power Calculations""; ""Author Index"" |
| Record Nr. | UNINA-9910780291203321 |
| Amsterdam ; ; Washington, DC : , : IOS Press, , 2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Free radicals, nitric oxide, and inflammation : molecular, biochemical, and clinical aspects / / edited by Aldo Tomasi, Tomris Ozben, and Vladimir P. Skulachev
| Free radicals, nitric oxide, and inflammation : molecular, biochemical, and clinical aspects / / edited by Aldo Tomasi, Tomris Ozben, and Vladimir P. Skulachev |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Washington, DC, : IOS Press, c2003 |
| Descrizione fisica | 1 online resource (vii, 255 pages) : illustrations |
| Disciplina | 616.0473 |
| Altri autori (Persone) |
TomasiAldo
OzbenTomris SkulachevV. P (Vladimir Petrovich) |
| Collana | NATO science series. Series I, Life and behavioural sciences |
| Soggetto topico |
Inflammation - Pathophysiology
Free radicals (Chemistry) - Pathophysiology Nitric oxide - Pathophysiology |
| ISBN |
1-60129-427-1
1-280-50545-1 600-00-0431-1 9786610505456 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Cover""; ""Title page""; ""Foreword""; ""Contents""; ""Alternative Functions of Mitochondria""; ""The Enzymatic Systems in the Regulation of Free Radical Lipid Peroxidation""; ""Flavanols and Procyanidins as Modulators of Oxidation in vitro and in vivo""; ""Estimation of Oxidative and Lipids Peroxidation DNA Adduct in Urine and DNA. Methodological Aspects and Application in Molecular Epidemiology""; ""Oxidative and Nitrosative Stress Mediated by Cyclosporine A in Endothelial Cells""; ""Early Signaling with Iron and Copper in Ischemic Preconditioning of the Heart""
""Multiple Mechanisms Regulating Endothelial Nitric Oxide Synthase"" ""Nitric Oxide. Its Generation, Reactions and Role in Physiology""; ""Redox-Regulated Glutathionylation of Transcription Factors: A Regulatory Mode for Gene Expression""; ""Sulphur-Containing Amino Acids, Glutathione and the Modulation of Inflammation""; ""Molecular Events of the Inflammation Process that are Affected by α-Tocopherol. Antioxidants and Gene Expression in the Process of Inflammation and Wound Repair""; ""Redox Regulation, Cytokine, and Nitric Oxide in Inflammation"" ""Non-Traditional Cardiovascular Disease Risk Factors and Arterial Inflammatory Response in End-Stage Renal Disease"" ""Significance of Reactive Oxygen Species for Neuronal Function""; ""Protein Aggregates and the Development of Neurodegenerative Diseases""; ""Inflammatory Response of the Brain Following Cerebral Ischemia""; ""Carnosine as Natural Antioxidant and Neuroprotector: Biological Functions and Possible Clinical Use""; ""Atherosclerosis as a Free Radical Pathology and Antioxidative Therapy of this Disease"" ""H[sub(2)]O[sub(2)] Sensors of Lungs and Blood Vessels and their Role in the Antioxidant Defense of the Body"" ""Oxidative Lung Injury""; ""Proper Design of Human Intervention Studies, Power Calculations""; ""Author Index"" |
| Record Nr. | UNINA-9910828434103321 |
| Amsterdam ; ; Washington, DC, : IOS Press, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Nitric Oxide : Biology and Pathobiology
| Nitric Oxide : Biology and Pathobiology |
| Autore | Ignarro Louis J |
| Edizione | [3rd ed.] |
| Pubbl/distr/stampa | San Diego : , : Elsevier Science & Technology, , 2017 |
| Descrizione fisica | 1 online resource (436 pages) |
| Disciplina |
572/.53
572.53 |
| Altri autori (Persone) | FreemanBruce |
| Soggetto topico |
Nitric oxide - Physiological effect
Nitric oxide - Pathophysiology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title Page -- Copyright Page -- Contents -- Contributors -- Introduction and Overview -- Chapter 1 - A Concise History of the Discovery of Mammalian Nitric Oxide (Nitrogen Monoxide) Biogenesis -- Introduction -- NO and NOx Prior to 1986 -- Ancient Human/NOx, NO Relationships -- The Discovery of NO and 19th-Century Studies -- 20th-Century NO Prior to 1986 -- 1986-88: Convergence of the Discovery of Endogenous NO in the Immune, Cardiovascular, and Nervous Systems -- NO in the Immune System Prior to 1986-88 -- NO in the Cardiovascular System Prior to 1986-88 -- NO in the Nervous System Prior to 1986-88 -- The Convergence: 1986-88 -- Conclusions -- References -- Chapter 2 - An Integrated View of the Chemical Biology of NO, CO, H2S, and O2 -- Introduction -- Nitric Oxide -- Carbon Monoxide -- Hydrogen Sulfide -- Dioxygen -- Superoxide -- Hydrogen Peroxide -- Hydroxyl Radical -- Chemical Biology of NO, CO, H2S, and O2 Interactions -- Interactions at Metal Centers: Heme Proteins -- The Effect of O2 and Derived Species on the Chemical Biology of NO, CO, and H2S -- Interaction of NO and H2S -- Thiols/Thiol Proteins and NO, CO, O2, and H2S Chemical Biology -- Summary -- References -- Chapter 3 - Detection of Nitric Oxide and Peroxynitrite in Biological Systems: A State-of-the-Art Review -- Detection of Nitric Oxide -- Introduction -- Detection of Nitrate and Nitrite -- Griess Reaction -- Chemiluminescence Detection of Nitrite/Nitrate -- Other Methods for Nitrite/Nitrate -- Probes for NO Detection -- Nitronyl Nitroxides -- Iron Dithiocarbamates -- Diaminofluorescein (DAF) -- S-Nitrosothiol Detection -- Detection of Liberated Nitrogen Oxides From S-Nitrosothiols -- Saville Reaction -- Chemiluminescence -- Detection of Protein S-Nitrosothiols -- Biotin Switch Assay -- Other Methods -- Detection of Peroxynitrite Using Boronate-Based Probes.
Introduction -- Oxidation of Boronates by Peroxynitrite and Other Biologically Relevant Oxidants -- Free Radical Pathway for the Reaction Between Boronates and ONOO− -- Real-Time Monitoring of ONOO− Formed In Situ in Cell-Free Systems -- Differentiation Between Different Oxidants Using Boronic Probes -- Detection of Peroxynitrite in Cellular Systems -- Perspectives for In Vivo Detection of Peroxynitrite -- Acknowledgment -- References -- Chapter 4 - S-Nitrosothiols and Nitric Oxide Biology -- Introduction -- RSNO Biochemistry: How Do RSNOs Relate to NO -- S-Nitrosothiol Levels and Targets In Vivo -- SNO Antibody -- RSNO Metabolism -- RSNO Formation -- Transnitrosation -- Denitrosation -- RSNO Transport -- Emerging Modulators of RSNO: Hydrogen Sulfide and Reactive Sulfur Species -- Biological Effects of RSNOs-Evidence and Interpretation -- RSNO Therapeutics -- RSNO as NO Donors -- Summary -- References -- Chapter 5 - Cooperative Interactions Between NO and H2S: Chemistry, Biology, Physiology, Pathophysiology -- Chemical Aspects of the NO/H2S Cross-Talk -- Introduction -- Basic Chemical Properties of Sulfide as Compared to NO -- Bioactive Intermediates of the Reaction Between NO and Sulfide (and its Various Metabolites): S/N Hybrid Molecules and Poly... -- HSNO/ONS− -- ONSS− -- Polysulfides -- SULFI/NO -- Regulation of NOS Activity by H2S -- Regulation of PIP3/AKT/eNOS by Sulfide -- Regulation of eNOS Activity Via H2S-Mediated Sulfhydration -- Inhibitory Effect of H2S on NOS Activity -- Inhibitory Effect of NO on CBS Activity -- Regulation of NOS Expression by H2S -- Regulation of eNOS Expression by H2S -- Regulation of iNOS Expression by H2S -- Regulation of nNOS Expression by H2S -- Regulation of CBS, CSE, or 3-MST by NO -- Support of the NO/cGMP/PKG Signaling Axis by H2S -- H2S, a Redox Reactivator of Soluble Guanylate Cyclase. H2S, an "Endogenous Viagra": Inhibition of PDE Activity by H2S -- Direct Reaction of H2S With cGMP: Formation of 8-SH-cGMP -- Oxidative Activation of Protein Kinase G by Sulfide-Derived Polysulfides -- Support of NO Signaling Through H2S/ROS Interactions -- Implications -- Implications of the NO/H2S Cooperative Interactions for the Regulation of Vascular Tone, Vascular Growth, and Remodeling -- Potential Cooperative Actions of NO and H2S in the Central and Peripheral Nervous System -- Potential Cooperative Actions of NO and H2S in Cancer -- On the Interdependence of NO and H2S Signaling and Cytoprotection -- Outlook: Future Therapeutic Directions -- References -- Chapter 6 - Heme Protein Metabolism of NO and Nitrite -- Introduction -- NO Inactivation by Reaction With Heme Proteins -- NO Reactions With Ferrous Hemoglobins to Form Iron-Nitrosyl Complexes [Fe(II)-NO] -- Effects of Red Blood Cell Compartmentalization of Hemoglobin on NO Reaction Rates -- NO Generation by Reaction of Nitrite With Deoxygenated Heme Proteins -- Conclusions -- Acknowledgments -- References -- Chapter 7 - Cross-Regulation Between iNOS/NO and Wnt/β-Catenin Signaling Pathways -- List of Abbreviations -- Introduction -- NO-Induced Posttranslational Modification of Wnt/β-Catenin Signaling Proteins -- iNOS-Derived NO Promotes β-Catenin Phosphorylation -- iNOS-Derived NO Induces Nitration and S-Nitrosation of Proteins Related to Wnt/β-Catenin Signaling Pathway -- iNOS/NO Induces Genetic Changes of Wnt/β-Catenin Pathway-Related Components -- Mutation of β-Catenin -- Loss of APC Heterozygosity -- iNOS/NO Regulates Wnt/β-Catenin Signaling -- iNOS/NO Targets Wnt/β-Catenin Signaling -- iNOS/NO Inversed DKK1 Expression Upregulated Wnt/β-Catenin Pathway -- iNOS/NO Regulates Both β-Catenin/TCF and NF-kB Transcriptional Functions -- iNOS Physically Interacts With β-Catenin. Wnt/β-Catenin Signaling Regulates iNOS/NO Pathway -- iNOS is a Targeted Gene of Wnt/β-Catenin Pathway -- Wnt/β-Catenin Regulated NF-kB Depending on the Induction of iNOS -- Conclusions -- References -- Chapter 8 - Regulation and Physiological Functions of NO-Sensitive Guanylyl Cyclase -- Introduction -- Isoforms and Molecular Properties of NO-Sensitive GC -- Activation of NO-GC by NO -- Novel Activators of NO-GC -- NO-GC Sensitizers and Heme-Mimetics in Clinical Testing -- NO-GC Inhibitors -- The NO/cGMP Signaling Cascade -- NO/cGMP-Induced Physiological Functions as Deduced From Genetic Deletion -- Blood Pressure Control -- Significance of NO-GC in Platelets -- Modulation of Synaptic Transmission -- LTP Is Lost in Both NO-GC KOs -- NO/cGMP in Glutamatergic Neurons -- NO/cGMP in GABAergic Neurons -- References -- Chapter 9 - Uncoupling of eNOS in Cardiovascular Disease -- Synthesis and Function of Endothelial NO -- The Phenomenon of eNOS Uncoupling -- Molecular Mechanisms of eNOS Uncoupling -- Uncoupling of eNOS in Cardiovascular Disease -- Hypertension -- Diabetes -- Atherosclerosis -- Pharmacological Prevention of eNOS Uncoupling -- Conclusions -- References -- Chapter 10 - Synthesis, Actions, and Perspectives of Nitric Oxide in Photosynthetic Organisms -- Nitric Oxide Synthesis in Photosynthetic Organisms -- Structure, Diversity, and Occurrence of Nitric Oxide Synthases (NOS) in Photosynthetic Organisms: Canonical NOS Is Absent i... -- Photosynthetic Organisms Do Not Synthetize the Biopterin Cofactor Required by NOS: The Role of Tetrahydrofolate -- Plants Possess Alternative Sources for NO Production -- Actions and Targets of NO in Photosynthetic Organisms -- NO as a Bioactive Signaling Molecule of Stress Responses in Land Plants -- Implications of NO in the Stress Responses of the Aquatic Photosynthetic Microorganisms. NO Is a Key Player in Auxin-Mediated Processes Leading to Root Growth and Development -- Targets and Molecular Mechanisms Underpinning NO Actions in Photosynthetic Organisms -- The Potential of NOS to Improve the Fitness of Crop Plants -- Concluding Remarks and Perspectives -- References -- Chapter 11 - Mitochondria and Nitric Oxide -- Introduction -- Sources of NO of Relevance to Mitochondria -- NO Inhibition of Cytochrome c Oxidase -- S-Nitrosation of Respiratory Complex i and Other Mitochondrial Proteins -- Mitochondrial Generation and Effects of Nitrated Fatty Acids -- Mitochondrial Generation and Effects of Peroxynitrite -- Cellular NO Signaling Regulation of Mitochondrial Dynamics and Number -- Summary and Integration of Concepts -- Acknowledgments -- References -- Chapter 12 - Nitric Oxide Formation From Inorganic Nitrate -- Introduction -- Sources of Nitrate and Nitrite -- The Enterosalivary Circulation of Nitrate -- Dietary Nitrate and Gastric Cancer -- Intragastric Generation of Nitric Oxide -- Interactions Between Nitrite and Other Dietary Compounds -- Systemic NO Generation From Nitrite -- Nitrite as a Vasodilator -- Mechanisms of Nitrite Reduction -- Dietary Nitrate and Cardiovascular Function -- Blood Pressure -- Pulmonary Hypertension -- Leukocyte and Platelet Activation -- Diabetes and Metabolic Syndrome -- How Is Inorganic Nitrate Bioactivated? -- Ergogenic Effects of Dietary Nitrate -- Nutritional Aspects -- References -- Chapter 13 - Biochemistry of Molybdopterin Nitrate/Nitrite Reductases -- Introduction -- Microbial Nitrate Reductases -- Eukaryotic Nitrate and Nitrite Reductases -- Xanthine Oxidoreductase -- Nitrate/Nitrite and Reducing Substrates -- Microenvironmental pH -- O2 Concentration -- Immobilization of XO on the Endothelial Glycocalyx -- Isoform of XOR -- Aldehyde Oxidase -- Sulfite Oxidase. Mitochondrial Amidoxime Reducing Component. |
| Record Nr. | UNINA-9910583324303321 |
Ignarro Louis J
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| San Diego : , : Elsevier Science & Technology, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pathophysiology and clinical applications of nitric oxide . Part B / / edited by Gabor M. Rubanyi
| Pathophysiology and clinical applications of nitric oxide . Part B / / edited by Gabor M. Rubanyi |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Amsterdam, : Harwood Academic, 1999 |
| Descrizione fisica | 1 online resource (378 p.) |
| Disciplina | 612.01524 |
| Altri autori (Persone) | RubanyiGabor M. <1947-> |
| Collana | Endothelial cell research series |
| Soggetto topico |
Nitric oxide - Pathophysiology
Nitrogen compounds |
| ISBN |
0-429-17673-2
1-4822-8349-2 1-280-05108-6 9786610051083 0-203-30372-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Book Cover; Half-Title; Title; Copyright; Dedication; Contents; Preface; Contributor; 13 Nitric Oxide and Its Role in Hemostasis; 14 Hypertension; 15 Pulmonary Hypertension; 16 Atherosclerosis: Role of NO; 17 Nitric Oxide in Myocardial and Splanchnic Ischemia/ Reperfusion; 18 Nitric Oxide and Circulatory Shock; 19 Kidney Diseases; 20 The Role of Nitric Oxide in Preterai Labour and Pre-eclampsia; 21 Multiple Sclerosis; 22 Regulation of Nitric Oxide and Inflammatory Mediators in Human Osteoarthritis-Affected Cartilage: Implication for Pharmacological Intervention
23 The Role of Nitric Oxide in Rheumatoid Arthritis 24 Gastrointestinal Function in Shock; 25 Nitric Oxide Donors; 26 Nitric Oxide Inhalation; 27 Nitric Oxide Synthase Inhibitors; 28 The Pharmacology of Peroxynitrite-Dependent Neurotoxicity Blockade; 29 Hemoglobin: Its Role as a Nitric Oxide Scavenger; 30 Therapeutic Implications of Recombinant Endothelial Nitric Oxide Synthase Gene Expression in Cerebral and Peripheral Arteries; 31 Gene Therapy Approaches with iNOS Edith Tzeng and Timothy R.Billiar; Index |
| Record Nr. | UNINA-9910821912703321 |
| Amsterdam, : Harwood Academic, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pathophysiology and clinical applications of nitric oxide / / edited by Gabor M. Rubanyi
| Pathophysiology and clinical applications of nitric oxide / / edited by Gabor M. Rubanyi |
| Pubbl/distr/stampa | Amsterdam : , : Harwood Academic Publishers, , 1990 |
| Descrizione fisica | 1 online resource (378 p.) |
| Disciplina | 612.01524 |
| Altri autori (Persone) | RubanyiGabor M. <1947-> |
| Collana | Endothelial cell research series |
| Soggetto topico |
Nitric oxide - Pathophysiology
Nitrogen compounds |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-429-17673-2
1-4822-8349-2 1-280-05108-6 9786610051083 0-203-30372-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Book Cover; Half-Title; Title; Copyright; Dedication; Contents; Preface; Contributor; 13 Nitric Oxide and Its Role in Hemostasis; 14 Hypertension; 15 Pulmonary Hypertension; 16 Atherosclerosis: Role of NO; 17 Nitric Oxide in Myocardial and Splanchnic Ischemia/ Reperfusion; 18 Nitric Oxide and Circulatory Shock; 19 Kidney Diseases; 20 The Role of Nitric Oxide in Preterai Labour and Pre-eclampsia; 21 Multiple Sclerosis; 22 Regulation of Nitric Oxide and Inflammatory Mediators in Human Osteoarthritis-Affected Cartilage: Implication for Pharmacological Intervention
23 The Role of Nitric Oxide in Rheumatoid Arthritis 24 Gastrointestinal Function in Shock; 25 Nitric Oxide Donors; 26 Nitric Oxide Inhalation; 27 Nitric Oxide Synthase Inhibitors; 28 The Pharmacology of Peroxynitrite-Dependent Neurotoxicity Blockade; 29 Hemoglobin: Its Role as a Nitric Oxide Scavenger; 30 Therapeutic Implications of Recombinant Endothelial Nitric Oxide Synthase Gene Expression in Cerebral and Peripheral Arteries; 31 Gene Therapy Approaches with iNOS Edith Tzeng and Timothy R.Billiar; Index |
| Record Nr. | UNINA-9910451207703321 |
| Amsterdam : , : Harwood Academic Publishers, , 1990 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pathophysiology and clinical applications of nitric oxide / / edited by Gabor M. Rubanyi
| Pathophysiology and clinical applications of nitric oxide / / edited by Gabor M. Rubanyi |
| Pubbl/distr/stampa | Amsterdam : , : Harwood Academic Publishers, , 1990 |
| Descrizione fisica | 1 online resource (378 p.) |
| Disciplina | 612.01524 |
| Altri autori (Persone) | RubanyiGabor M. <1947-> |
| Collana | Endothelial cell research series |
| Soggetto topico |
Nitric oxide - Pathophysiology
Nitrogen compounds |
| ISBN |
0-429-17673-2
1-4822-8349-2 1-280-05108-6 9786610051083 0-203-30372-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Book Cover; Half-Title; Title; Copyright; Dedication; Contents; Preface; Contributor; 13 Nitric Oxide and Its Role in Hemostasis; 14 Hypertension; 15 Pulmonary Hypertension; 16 Atherosclerosis: Role of NO; 17 Nitric Oxide in Myocardial and Splanchnic Ischemia/ Reperfusion; 18 Nitric Oxide and Circulatory Shock; 19 Kidney Diseases; 20 The Role of Nitric Oxide in Preterai Labour and Pre-eclampsia; 21 Multiple Sclerosis; 22 Regulation of Nitric Oxide and Inflammatory Mediators in Human Osteoarthritis-Affected Cartilage: Implication for Pharmacological Intervention
23 The Role of Nitric Oxide in Rheumatoid Arthritis 24 Gastrointestinal Function in Shock; 25 Nitric Oxide Donors; 26 Nitric Oxide Inhalation; 27 Nitric Oxide Synthase Inhibitors; 28 The Pharmacology of Peroxynitrite-Dependent Neurotoxicity Blockade; 29 Hemoglobin: Its Role as a Nitric Oxide Scavenger; 30 Therapeutic Implications of Recombinant Endothelial Nitric Oxide Synthase Gene Expression in Cerebral and Peripheral Arteries; 31 Gene Therapy Approaches with iNOS Edith Tzeng and Timothy R.Billiar; Index |
| Record Nr. | UNINA-9910783978903321 |
| Amsterdam : , : Harwood Academic Publishers, , 1990 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
