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Neutrophils / / edited by Maitham Khajah
Neutrophils / / edited by Maitham Khajah
Pubbl/distr/stampa London, United Kingdom : , : IntechOpen, , 2019
Descrizione fisica 1 online resource (98 pages) : illustrations some color
Disciplina 616.079
Soggetto topico Neutrophils
ISBN 1-83962-005-6
1-78985-286-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910317764503321
London, United Kingdom : , : IntechOpen, , 2019
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The neutrophils [[electronic resource] ] : new outlook for old cells / / editor, Dmitry I. Gabrilovich
The neutrophils [[electronic resource] ] : new outlook for old cells / / editor, Dmitry I. Gabrilovich
Edizione [3rd ed.]
Pubbl/distr/stampa London, : Imperial College Press
Descrizione fisica 1 online resource (447 p.)
Disciplina 571.96
Altri autori (Persone) GabrilovichDmitry I
Soggetto topico Neutrophils
Immunology
Soggetto genere / forma Electronic books.
ISBN 1-299-46292-8
1-84816-837-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto List of Contributors; Preface; Contents; Chapter 1: Molecular Regulation of Granulopoiesis Sachin Kumar and Marie-Dominique Filippi; 1.1 Introduction; 1.2 Sequential Steps of PMN Development; 1.2.1 From HSC to granulocytic precursors; 1.2.2 Final stages of granulocytic maturation - Acquisition of granulocyte characteristics; 1.3 Regulation of Steady State Granulopoiesis; 1.3.1 Growth factors; 1.3.1.1 G-CSF: Sources and functions; 1.3.1.2 G-CSFR and downstream signaling pathways; 1.3.1.3 G-CSFR signaling: Instructive or permissive?; 1.3.2 Transcription factors (TF)
1.3.2.1 PU.1 - Generation of CMP from HSC1.3.2.2 C/EBPα - Generation of GMP from CMP; 1.3.2.3 C/EBPε - Terminal stages of differentiation; 1.3.2.4 Gfi-1 - Terminal stages of differentiation; 1.3.2.5 Other transcription factors important for granulopoiesis; 1.3.2.5.1 Retinoic acid receptors; 1.3.2.5.2 HoxA10; 1.3.2.5.3 LEF-1; 1.3.3 MicroRNA; 1.3.4 Cell cycle regulation; 1.4 Emergency Granulopoiesis; 1.5 Conclusion; References; Chapter 2: The Neutrophil Respiratory Burst Oxidase Mark T. Quinn; 2.1 Introduction; 2.2 NADPH Oxidase Components; 2.2.1 Flavocytochrome b; 2.2.2 p47phox; 2.2.3 p67phox
2.2.4 p40phox2.2.5 Rac; 2.2.6 Rap1A; 2.3 Oxidase Protein Binding Interactions; 2.3.1 Flavocytochrome b-p47phox interactions; 2.3.2 p40phox-p47phox-p67phox interactions; 2.3.3 Rac interactions; 2.4 Model of NADPH Oxidase Assembly; 2.5 Oxidant Production; 2.5.1 Superoxide anion (O2 -); 2.5.2 Hydrogen peroxide (H2O2); 2.5.3 Hypochlorous acid (HOCl); 2.5.4 Hydroxyl radical (HO); 2.5.5 Singlet oxygen ( 1O2 *); 2.5.6 Nitric oxide (NO) and peroxynitrite (ONOO-); 2.7 Summary; Acknowledgments; References
Chapter 3: Novel Neutrophil Receptors and Their Signal Transduction Nicole R. Fortenbery, Xianhong Chen and Sheng Wei3.1 Introduction; 3.2 Siglecs; 3.2.1 Identification of siglecs; 3.2.2 Characterization of siglecs; 3.2.3 Siglec-5; 3.2.4 Siglec-9; 3.2.5 Siglec-14; 3.2.6 Siglec signaling; 3.2.7 Clinical applications; 3.3 Triggering Receptor Expressed by Myeloid Cells (TREM); 3.3.1 Identification of TREM; 3.3.2 Characterization of TREM-1; 3.3.3 TREM-1-DAP12 and signal transduction; 3.3.4 TREM-1 ligand(s); References
Chapter 4 Mechanisms of Neutrophil Migration Fong W. Lam, Rolando E. Rumbaut and Alan R. Burns4.1 Introduction; 4.2 Historical Perspective on Leukocyte Adhesion and Emigration (1669-1955); 4.2.1 The first observations; 4.2.2 Mechanistic insight; 4.3 Molecular Adhesive Events Preceding Neutrophil Transendothelial Migration; 4.4 Integrin Regulation of Neutrophil Transendothelial Migration; 4.5 Paracellular Neutrophil Transendothelial Migration; 4.5.1 Endothelial cleft organization; 4.5.2 Tight junctions and preferred transmigration sites; 4.5.3 Adherens junctions; 4.5.4 Gap junctions
4.5.5 PECAM-1
Record Nr. UNINA-9910452307003321
London, : Imperial College Press
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The neutrophils : new outlook for old cells / / editor, Dmitry Gabrilovich, H. Lee Moffitt Cancer Center, USA, University of South Florida, USA
The neutrophils : new outlook for old cells / / editor, Dmitry Gabrilovich, H. Lee Moffitt Cancer Center, USA, University of South Florida, USA
Edizione [3rd ed.]
Pubbl/distr/stampa London, : Imperial College Press
Descrizione fisica 1 online resource (xxiii, 422 pages) : illustrations (some color)
Disciplina 571.96
Collana Gale eBooks
Soggetto topico Neutrophils
ISBN 1-299-46292-8
1-84816-837-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto List of Contributors; Preface; Contents; Chapter 1: Molecular Regulation of Granulopoiesis Sachin Kumar and Marie-Dominique Filippi; 1.1 Introduction; 1.2 Sequential Steps of PMN Development; 1.2.1 From HSC to granulocytic precursors; 1.2.2 Final stages of granulocytic maturation - Acquisition of granulocyte characteristics; 1.3 Regulation of Steady State Granulopoiesis; 1.3.1 Growth factors; 1.3.1.1 G-CSF: Sources and functions; 1.3.1.2 G-CSFR and downstream signaling pathways; 1.3.1.3 G-CSFR signaling: Instructive or permissive?; 1.3.2 Transcription factors (TF)
1.3.2.1 PU.1 - Generation of CMP from HSC1.3.2.2 C/EBPα - Generation of GMP from CMP; 1.3.2.3 C/EBPε - Terminal stages of differentiation; 1.3.2.4 Gfi-1 - Terminal stages of differentiation; 1.3.2.5 Other transcription factors important for granulopoiesis; 1.3.2.5.1 Retinoic acid receptors; 1.3.2.5.2 HoxA10; 1.3.2.5.3 LEF-1; 1.3.3 MicroRNA; 1.3.4 Cell cycle regulation; 1.4 Emergency Granulopoiesis; 1.5 Conclusion; References; Chapter 2: The Neutrophil Respiratory Burst Oxidase Mark T. Quinn; 2.1 Introduction; 2.2 NADPH Oxidase Components; 2.2.1 Flavocytochrome b; 2.2.2 p47phox; 2.2.3 p67phox
2.2.4 p40phox2.2.5 Rac; 2.2.6 Rap1A; 2.3 Oxidase Protein Binding Interactions; 2.3.1 Flavocytochrome b-p47phox interactions; 2.3.2 p40phox-p47phox-p67phox interactions; 2.3.3 Rac interactions; 2.4 Model of NADPH Oxidase Assembly; 2.5 Oxidant Production; 2.5.1 Superoxide anion (O2 -); 2.5.2 Hydrogen peroxide (H2O2); 2.5.3 Hypochlorous acid (HOCl); 2.5.4 Hydroxyl radical (HO); 2.5.5 Singlet oxygen ( 1O2 *); 2.5.6 Nitric oxide (NO) and peroxynitrite (ONOO-); 2.7 Summary; Acknowledgments; References
Chapter 3: Novel Neutrophil Receptors and Their Signal Transduction Nicole R. Fortenbery, Xianhong Chen and Sheng Wei3.1 Introduction; 3.2 Siglecs; 3.2.1 Identification of siglecs; 3.2.2 Characterization of siglecs; 3.2.3 Siglec-5; 3.2.4 Siglec-9; 3.2.5 Siglec-14; 3.2.6 Siglec signaling; 3.2.7 Clinical applications; 3.3 Triggering Receptor Expressed by Myeloid Cells (TREM); 3.3.1 Identification of TREM; 3.3.2 Characterization of TREM-1; 3.3.3 TREM-1-DAP12 and signal transduction; 3.3.4 TREM-1 ligand(s); References
Chapter 4 Mechanisms of Neutrophil Migration Fong W. Lam, Rolando E. Rumbaut and Alan R. Burns4.1 Introduction; 4.2 Historical Perspective on Leukocyte Adhesion and Emigration (1669-1955); 4.2.1 The first observations; 4.2.2 Mechanistic insight; 4.3 Molecular Adhesive Events Preceding Neutrophil Transendothelial Migration; 4.4 Integrin Regulation of Neutrophil Transendothelial Migration; 4.5 Paracellular Neutrophil Transendothelial Migration; 4.5.1 Endothelial cleft organization; 4.5.2 Tight junctions and preferred transmigration sites; 4.5.3 Adherens junctions; 4.5.4 Gap junctions
4.5.5 PECAM-1
Record Nr. UNINA-9910779691003321
London, : Imperial College Press
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The neutrophils : new outlook for old cells / / editor, Dmitry Gabrilovich, H. Lee Moffitt Cancer Center, USA, University of South Florida, USA
The neutrophils : new outlook for old cells / / editor, Dmitry Gabrilovich, H. Lee Moffitt Cancer Center, USA, University of South Florida, USA
Edizione [3rd ed.]
Pubbl/distr/stampa London, : Imperial College Press
Descrizione fisica 1 online resource (xxiii, 422 pages) : illustrations (some color)
Disciplina 571.96
Collana Gale eBooks
Soggetto topico Neutrophils
ISBN 1-299-46292-8
1-84816-837-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto List of Contributors; Preface; Contents; Chapter 1: Molecular Regulation of Granulopoiesis Sachin Kumar and Marie-Dominique Filippi; 1.1 Introduction; 1.2 Sequential Steps of PMN Development; 1.2.1 From HSC to granulocytic precursors; 1.2.2 Final stages of granulocytic maturation - Acquisition of granulocyte characteristics; 1.3 Regulation of Steady State Granulopoiesis; 1.3.1 Growth factors; 1.3.1.1 G-CSF: Sources and functions; 1.3.1.2 G-CSFR and downstream signaling pathways; 1.3.1.3 G-CSFR signaling: Instructive or permissive?; 1.3.2 Transcription factors (TF)
1.3.2.1 PU.1 - Generation of CMP from HSC1.3.2.2 C/EBPα - Generation of GMP from CMP; 1.3.2.3 C/EBPε - Terminal stages of differentiation; 1.3.2.4 Gfi-1 - Terminal stages of differentiation; 1.3.2.5 Other transcription factors important for granulopoiesis; 1.3.2.5.1 Retinoic acid receptors; 1.3.2.5.2 HoxA10; 1.3.2.5.3 LEF-1; 1.3.3 MicroRNA; 1.3.4 Cell cycle regulation; 1.4 Emergency Granulopoiesis; 1.5 Conclusion; References; Chapter 2: The Neutrophil Respiratory Burst Oxidase Mark T. Quinn; 2.1 Introduction; 2.2 NADPH Oxidase Components; 2.2.1 Flavocytochrome b; 2.2.2 p47phox; 2.2.3 p67phox
2.2.4 p40phox2.2.5 Rac; 2.2.6 Rap1A; 2.3 Oxidase Protein Binding Interactions; 2.3.1 Flavocytochrome b-p47phox interactions; 2.3.2 p40phox-p47phox-p67phox interactions; 2.3.3 Rac interactions; 2.4 Model of NADPH Oxidase Assembly; 2.5 Oxidant Production; 2.5.1 Superoxide anion (O2 -); 2.5.2 Hydrogen peroxide (H2O2); 2.5.3 Hypochlorous acid (HOCl); 2.5.4 Hydroxyl radical (HO); 2.5.5 Singlet oxygen ( 1O2 *); 2.5.6 Nitric oxide (NO) and peroxynitrite (ONOO-); 2.7 Summary; Acknowledgments; References
Chapter 3: Novel Neutrophil Receptors and Their Signal Transduction Nicole R. Fortenbery, Xianhong Chen and Sheng Wei3.1 Introduction; 3.2 Siglecs; 3.2.1 Identification of siglecs; 3.2.2 Characterization of siglecs; 3.2.3 Siglec-5; 3.2.4 Siglec-9; 3.2.5 Siglec-14; 3.2.6 Siglec signaling; 3.2.7 Clinical applications; 3.3 Triggering Receptor Expressed by Myeloid Cells (TREM); 3.3.1 Identification of TREM; 3.3.2 Characterization of TREM-1; 3.3.3 TREM-1-DAP12 and signal transduction; 3.3.4 TREM-1 ligand(s); References
Chapter 4 Mechanisms of Neutrophil Migration Fong W. Lam, Rolando E. Rumbaut and Alan R. Burns4.1 Introduction; 4.2 Historical Perspective on Leukocyte Adhesion and Emigration (1669-1955); 4.2.1 The first observations; 4.2.2 Mechanistic insight; 4.3 Molecular Adhesive Events Preceding Neutrophil Transendothelial Migration; 4.4 Integrin Regulation of Neutrophil Transendothelial Migration; 4.5 Paracellular Neutrophil Transendothelial Migration; 4.5.1 Endothelial cleft organization; 4.5.2 Tight junctions and preferred transmigration sites; 4.5.3 Adherens junctions; 4.5.4 Gap junctions
4.5.5 PECAM-1
Record Nr. UNINA-9910809264503321
London, : Imperial College Press
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The neutrophils [[electronic resource] ] : new outlook for old cells / / editor, Dmitry I. Gabrilovich
The neutrophils [[electronic resource] ] : new outlook for old cells / / editor, Dmitry I. Gabrilovich
Edizione [2nd ed.]
Pubbl/distr/stampa Hackensack, N.J., : Imperial College Press, 2004
Descrizione fisica 1 online resource (378 p.)
Disciplina 612.1/12
Altri autori (Persone) GabrilovichDmitry I
Soggetto topico Neutrophils
Physiology
Soggetto genere / forma Electronic books.
ISBN 1-281-86662-8
9786611866624
1-86094-605-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Preface; Contributors; 1 The Remarkable Neutrophil! Developing a Blueprint for Integrated Cellular Signaling; 2 The Neutrophil Respiratory Burst Oxidase; 3 Novel Neutrophil Receptors and Their Signal Transduction; 4 Mechanisms of Neutrophil Migration; 5 Neutrophils and Apoptosis; 6 Regulation of Neutrophil Functions by Long Chain Fatty Acids; 7 Cytokine Production by Neutrophils; 8 Neutrophils in Viral Infections; 9 Polymorphonuclear Neutrophils and Cancer: Ambivalent Role in Host Defense Against Tumor
10 Use of Colony-Stimulating Factors for Treatment of Neutropenia and Infectious Diseases11 Neutrophil Transfusion Therapy in the G-CSF Era; Index
Record Nr. UNINA-9910449805403321
Hackensack, N.J., : Imperial College Press, 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The neutrophils [[electronic resource] ] : new outlook for old cells / / editor, Dmitry I. Gabrilovich
The neutrophils [[electronic resource] ] : new outlook for old cells / / editor, Dmitry I. Gabrilovich
Edizione [2nd ed.]
Pubbl/distr/stampa Hackensack, N.J., : Imperial College Press, 2004
Descrizione fisica 1 online resource (378 p.)
Disciplina 612.1/12
Altri autori (Persone) GabrilovichDmitry I
Soggetto topico Neutrophils
Physiology
ISBN 1-281-86662-8
9786611866624
1-86094-605-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Preface; Contributors; 1 The Remarkable Neutrophil! Developing a Blueprint for Integrated Cellular Signaling; 2 The Neutrophil Respiratory Burst Oxidase; 3 Novel Neutrophil Receptors and Their Signal Transduction; 4 Mechanisms of Neutrophil Migration; 5 Neutrophils and Apoptosis; 6 Regulation of Neutrophil Functions by Long Chain Fatty Acids; 7 Cytokine Production by Neutrophils; 8 Neutrophils in Viral Infections; 9 Polymorphonuclear Neutrophils and Cancer: Ambivalent Role in Host Defense Against Tumor
10 Use of Colony-Stimulating Factors for Treatment of Neutropenia and Infectious Diseases11 Neutrophil Transfusion Therapy in the G-CSF Era; Index
Record Nr. UNINA-9910783405903321
Hackensack, N.J., : Imperial College Press, 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The neutrophils [[electronic resource] ] : new outlook for old cells / / editor, Dmitry I. Gabrilovich
The neutrophils [[electronic resource] ] : new outlook for old cells / / editor, Dmitry I. Gabrilovich
Edizione [2nd ed.]
Pubbl/distr/stampa Hackensack, N.J., : Imperial College Press, 2004
Descrizione fisica 1 online resource (378 p.)
Disciplina 612.1/12
Altri autori (Persone) GabrilovichDmitry I
Soggetto topico Neutrophils
Physiology
ISBN 1-281-86662-8
9786611866624
1-86094-605-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Preface; Contributors; 1 The Remarkable Neutrophil! Developing a Blueprint for Integrated Cellular Signaling; 2 The Neutrophil Respiratory Burst Oxidase; 3 Novel Neutrophil Receptors and Their Signal Transduction; 4 Mechanisms of Neutrophil Migration; 5 Neutrophils and Apoptosis; 6 Regulation of Neutrophil Functions by Long Chain Fatty Acids; 7 Cytokine Production by Neutrophils; 8 Neutrophils in Viral Infections; 9 Polymorphonuclear Neutrophils and Cancer: Ambivalent Role in Host Defense Against Tumor
10 Use of Colony-Stimulating Factors for Treatment of Neutropenia and Infectious Diseases11 Neutrophil Transfusion Therapy in the G-CSF Era; Index
Record Nr. UNINA-9910819886403321
Hackensack, N.J., : Imperial College Press, 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Neutrophils in infectious diseases [[electronic resource] /] / edited by Fabienne Tacchini-Cottier and Ger van Zandbergen
Neutrophils in infectious diseases [[electronic resource] /] / edited by Fabienne Tacchini-Cottier and Ger van Zandbergen
Pubbl/distr/stampa [Oak Park, Ill.?], : Bentham eBooks, [2011]
Descrizione fisica 1 online resource (89 p.)
Disciplina 616.079
Altri autori (Persone) Tacchini-CottierFabienne
ZandbergenGer van
Soggetto topico Neutrophils
Neutrophils - Immunology
Communicable diseases
Soggetto genere / forma Electronic books.
ISBN 1-60805-023-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 01 Title.pdf; 02 Cover page; 03 eBooks End User License Agreement-Website; 04 Content; 05 Foreword; 06 Preface; 07 Contributors; 09 Part; 10 Chapter 01; 11 Chapter 02; 12 Part A; 13 Chapter 03; 14 Chapter 04; 15 Chapter 05; 16 Part B; 17 Chapter 06; 18 Chapter 07; 19 Chapter 08; 20 Index
Record Nr. UNINA-9910457197203321
[Oak Park, Ill.?], : Bentham eBooks, [2011]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Neutrophils in infectious diseases [[electronic resource] /] / edited by Fabienne Tacchini-Cottier and Ger van Zandbergen
Neutrophils in infectious diseases [[electronic resource] /] / edited by Fabienne Tacchini-Cottier and Ger van Zandbergen
Pubbl/distr/stampa [Oak Park, Ill.?], : Bentham eBooks, [2011]
Descrizione fisica 1 online resource (89 p.)
Disciplina 616.079
Altri autori (Persone) Tacchini-CottierFabienne
ZandbergenGer van
Soggetto topico Neutrophils
Neutrophils - Immunology
Communicable diseases
ISBN 1-60805-023-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 01 Title.pdf; 02 Cover page; 03 eBooks End User License Agreement-Website; 04 Content; 05 Foreword; 06 Preface; 07 Contributors; 09 Part; 10 Chapter 01; 11 Chapter 02; 12 Part A; 13 Chapter 03; 14 Chapter 04; 15 Chapter 05; 16 Part B; 17 Chapter 06; 18 Chapter 07; 19 Chapter 08; 20 Index
Record Nr. UNINA-9910781972603321
[Oak Park, Ill.?], : Bentham eBooks, [2011]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Neutrophils in infectious diseases [[electronic resource] /] / edited by Fabienne Tacchini-Cottier and Ger van Zandbergen
Neutrophils in infectious diseases [[electronic resource] /] / edited by Fabienne Tacchini-Cottier and Ger van Zandbergen
Edizione [1st ed.]
Pubbl/distr/stampa [Oak Park, Ill.?], : Bentham eBooks, [2011]
Descrizione fisica 1 online resource (89 p.)
Disciplina 616.079
Altri autori (Persone) Tacchini-CottierFabienne
ZandbergenGer van
Soggetto topico Neutrophils
Neutrophils - Immunology
Communicable diseases
ISBN 1-60805-023-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 01 Title.pdf; 02 Cover page; 03 eBooks End User License Agreement-Website; 04 Content; 05 Foreword; 06 Preface; 07 Contributors; 09 Part; 10 Chapter 01; 11 Chapter 02; 12 Part A; 13 Chapter 03; 14 Chapter 04; 15 Chapter 05; 16 Part B; 17 Chapter 06; 18 Chapter 07; 19 Chapter 08; 20 Index
Record Nr. UNINA-9910808994403321
[Oak Park, Ill.?], : Bentham eBooks, [2011]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui