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Analysis, occurrence, and toxicity of c-methylaminoalanine (BMAA) [[electronic resource] ] : a risk for the consumer?
| Analysis, occurrence, and toxicity of c-methylaminoalanine (BMAA) [[electronic resource] ] : a risk for the consumer? |
| Pubbl/distr/stampa | Copenhagen, : Nordic Council of Ministers, c2007 |
| Descrizione fisica | 1 online resource (131 p.) |
| Collana | TemaNord |
| Soggetto topico |
Amino acids - Toxicology
Neurotoxic agents |
| Soggetto genere / forma | Electronic books. |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Content""; ""Preface""; ""Summary in English""; "" 1. Introduction""; "" 2. A historical perspective on the link between BMAA exposure and degenerative neurological disease""; ""2.1 Conclusions on cycad and BMAA exposure and degenerative neurological disease""; ""3. Case reports on animals, toxicological studies on cycad materials and preparations ""; ""3.1 Case reports on animals""; ""3.2 Studies on primates fed preparations from Cycas circinalis""; ""3.3 Studies on rodents fed preparations from Cycas circinalis""; ""3.4 Rodent studies on other cycad species than C. circinalis""
""3.5 Conclusions on case reports and toxicological studies performed with cycad preparations. """"4. BMAA as a natural toxicant in cycads and studies on BMAA toxicity""; ""4.1 Biosynthesis""; ""4.2 Effects in plants � a possible mechanism of action""; ""4.3 Toxicokinetics""; ""4.4 In vivo studies ""; ""4.5 Studies on infusion of BMAA directly into brain or brain ventricles""; ""4.6 In vitro studies ""; ""4.7 Conclusions on BMAA as a natural toxicant in cycads and on studies of BMAA toxicity""; ""5. Identity and physical and chemical properties of BMAA, and its chemical analysis"" ""5.1 Identity """"5.2 Physical and chemical properties""; ""5.3 Carbamates""; ""5.4 Bound BMAA""; ""5.5 Methods of analysis""; ""5.6 Development of an LC-MS/MS method and analysis of BMAA in cycads and cyanobacteria""; ""5.7 Analysis of cyanobacteria with HPLC and the ninhydrin reaction""; "" 5.8 Conclusion on physical and chemical properties of BMAA and methods of analysis""; ""6. Occurrence of BMAA i cycads""; ""6.1 Cycad plants from the genus Cycas""; ""6.2 Cycad flour""; ""6.3 Conclusions on occurrence of BMAA in cycads"" ""7. The theory of biomagnification and identification of BMAA in human tissues""""7.1 Flying foxes""; ""7.2 Brain material and other tissues from control individuals and patients with degenerative neurological disease""; ""7.3 Conclusion on the theory of biomagnification of BMAA and identification of BMAA in human tissues""; ""8. Is BMAA produced by cyanobacteria ""; ""Conclusion on possible production of BMAA by cyanobacteria""; ""9. Conclusions""; ""10. Recommendations""; "" Sammanfattning (Summary in Swedish)""; "" 11. References""; "" Annex 1""; ""Summaries of epidemiological studies"" ""Annex 2""""Table 1. In vivo studies on cycad preparations""; "" Table 2. In vivo studies on BMAA."" |
| Record Nr. | UNINA-9910452899803321 |
| Copenhagen, : Nordic Council of Ministers, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Analysis, occurrence, and toxicity of c-methylaminoalanine (BMAA) [[electronic resource] ] : a risk for the consumer?
| Analysis, occurrence, and toxicity of c-methylaminoalanine (BMAA) [[electronic resource] ] : a risk for the consumer? |
| Pubbl/distr/stampa | Copenhagen, : Nordic Council of Ministers, c2007 |
| Descrizione fisica | 1 online resource (131 p.) |
| Collana | TemaNord |
| Soggetto topico |
Amino acids - Toxicology
Neurotoxic agents |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Content""; ""Preface""; ""Summary in English""; "" 1. Introduction""; "" 2. A historical perspective on the link between BMAA exposure and degenerative neurological disease""; ""2.1 Conclusions on cycad and BMAA exposure and degenerative neurological disease""; ""3. Case reports on animals, toxicological studies on cycad materials and preparations ""; ""3.1 Case reports on animals""; ""3.2 Studies on primates fed preparations from Cycas circinalis""; ""3.3 Studies on rodents fed preparations from Cycas circinalis""; ""3.4 Rodent studies on other cycad species than C. circinalis""
""3.5 Conclusions on case reports and toxicological studies performed with cycad preparations. """"4. BMAA as a natural toxicant in cycads and studies on BMAA toxicity""; ""4.1 Biosynthesis""; ""4.2 Effects in plants � a possible mechanism of action""; ""4.3 Toxicokinetics""; ""4.4 In vivo studies ""; ""4.5 Studies on infusion of BMAA directly into brain or brain ventricles""; ""4.6 In vitro studies ""; ""4.7 Conclusions on BMAA as a natural toxicant in cycads and on studies of BMAA toxicity""; ""5. Identity and physical and chemical properties of BMAA, and its chemical analysis"" ""5.1 Identity """"5.2 Physical and chemical properties""; ""5.3 Carbamates""; ""5.4 Bound BMAA""; ""5.5 Methods of analysis""; ""5.6 Development of an LC-MS/MS method and analysis of BMAA in cycads and cyanobacteria""; ""5.7 Analysis of cyanobacteria with HPLC and the ninhydrin reaction""; "" 5.8 Conclusion on physical and chemical properties of BMAA and methods of analysis""; ""6. Occurrence of BMAA i cycads""; ""6.1 Cycad plants from the genus Cycas""; ""6.2 Cycad flour""; ""6.3 Conclusions on occurrence of BMAA in cycads"" ""7. The theory of biomagnification and identification of BMAA in human tissues""""7.1 Flying foxes""; ""7.2 Brain material and other tissues from control individuals and patients with degenerative neurological disease""; ""7.3 Conclusion on the theory of biomagnification of BMAA and identification of BMAA in human tissues""; ""8. Is BMAA produced by cyanobacteria ""; ""Conclusion on possible production of BMAA by cyanobacteria""; ""9. Conclusions""; ""10. Recommendations""; "" Sammanfattning (Summary in Swedish)""; "" 11. References""; "" Annex 1""; ""Summaries of epidemiological studies"" ""Annex 2""""Table 1. In vivo studies on cycad preparations""; "" Table 2. In vivo studies on BMAA."" |
| Record Nr. | UNINA-9910779384203321 |
| Copenhagen, : Nordic Council of Ministers, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Analysis, occurrence, and toxicity of c-methylaminoalanine (BMAA) : a risk for the consumer?
| Analysis, occurrence, and toxicity of c-methylaminoalanine (BMAA) : a risk for the consumer? |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Copenhagen, : Nordic Council of Ministers, c2007 |
| Descrizione fisica | 1 online resource (131 p.) |
| Collana | TemaNord |
| Soggetto topico |
Amino acids - Toxicology
Neurotoxic agents |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Content""; ""Preface""; ""Summary in English""; "" 1. Introduction""; "" 2. A historical perspective on the link between BMAA exposure and degenerative neurological disease""; ""2.1 Conclusions on cycad and BMAA exposure and degenerative neurological disease""; ""3. Case reports on animals, toxicological studies on cycad materials and preparations ""; ""3.1 Case reports on animals""; ""3.2 Studies on primates fed preparations from Cycas circinalis""; ""3.3 Studies on rodents fed preparations from Cycas circinalis""; ""3.4 Rodent studies on other cycad species than C. circinalis""
""3.5 Conclusions on case reports and toxicological studies performed with cycad preparations. """"4. BMAA as a natural toxicant in cycads and studies on BMAA toxicity""; ""4.1 Biosynthesis""; ""4.2 Effects in plants � a possible mechanism of action""; ""4.3 Toxicokinetics""; ""4.4 In vivo studies ""; ""4.5 Studies on infusion of BMAA directly into brain or brain ventricles""; ""4.6 In vitro studies ""; ""4.7 Conclusions on BMAA as a natural toxicant in cycads and on studies of BMAA toxicity""; ""5. Identity and physical and chemical properties of BMAA, and its chemical analysis"" ""5.1 Identity """"5.2 Physical and chemical properties""; ""5.3 Carbamates""; ""5.4 Bound BMAA""; ""5.5 Methods of analysis""; ""5.6 Development of an LC-MS/MS method and analysis of BMAA in cycads and cyanobacteria""; ""5.7 Analysis of cyanobacteria with HPLC and the ninhydrin reaction""; "" 5.8 Conclusion on physical and chemical properties of BMAA and methods of analysis""; ""6. Occurrence of BMAA i cycads""; ""6.1 Cycad plants from the genus Cycas""; ""6.2 Cycad flour""; ""6.3 Conclusions on occurrence of BMAA in cycads"" ""7. The theory of biomagnification and identification of BMAA in human tissues""""7.1 Flying foxes""; ""7.2 Brain material and other tissues from control individuals and patients with degenerative neurological disease""; ""7.3 Conclusion on the theory of biomagnification of BMAA and identification of BMAA in human tissues""; ""8. Is BMAA produced by cyanobacteria ""; ""Conclusion on possible production of BMAA by cyanobacteria""; ""9. Conclusions""; ""10. Recommendations""; "" Sammanfattning (Summary in Swedish)""; "" 11. References""; "" Annex 1""; ""Summaries of epidemiological studies"" ""Annex 2""""Table 1. In vivo studies on cycad preparations""; "" Table 2. In vivo studies on BMAA."" |
| Altri titoli varianti | Beta-methylaminoalanine (BMAA) |
| Record Nr. | UNINA-9910821380903321 |
| Copenhagen, : Nordic Council of Ministers, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Botulinum neurotoxins / / Andreas Rummel, Thomas Binz, editors
| Botulinum neurotoxins / / Andreas Rummel, Thomas Binz, editors |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, : Springer, 2013 |
| Descrizione fisica | 1 online resource (321 p.) |
| Disciplina |
615.9/5
615.95 |
| Altri autori (Persone) |
RummelAndreas
BinzThomas |
| Collana | Current topics in microbiology and immunology |
| Soggetto topico |
Botulinum toxin
Neurotoxic agents |
| ISBN |
1-283-93528-7
3-642-33570-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Genetic Diversity Within Clostridium botulinum Serotypes, Botulinum Neurotoxin Gene Clusters and Toxin Subtypes -- Assembly and Function of the Botulinum Neurotoxin Progenitor Complex -- Uptake of Botulinum Neurotoxin in the Intestine -- Double Receptor Anchorage of Botulinum Neurotoxins Accounts for their Exquisite Neurospecificity -- The Elusive Compass of Clostridial Neurotoxins: Deciding When and Where to Go? -- Synchronized Chaperone Function of Botulinum Neurotoxin Domains Mediates Light Chain Translocation into Neurons -- Clostridial Neurotoxin Light Chains: Devices for SNARE Cleavage Mediated Blockade of Neurotransmission -- Synaptic Vesicle Proteins: Targets and Routes for Botulinum Neurotoxins -- Persistence of Botulinum Neurotoxin Inactivation of Nerve Function -- Structure-Based Drug Discovery for Botulinum Neurotoxins -- Complexity of Botulinum Neurotoxins: Challenges for Detection Technology -- Progress in Cell Based Assays for Botulinum Neurotoxin Detection -- Transforming the Domain Structure of Botulinum Neurotoxins into Novel Therapeutics -- Botulinum Toxin: Application, Safety, and Limitations. |
| Record Nr. | UNINA-9910437826803321 |
| New York, : Springer, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Developmental neurotoxicity of PBDEs, mechanisms and implications [[electronic resource] /] / Henrik Alm and Birger Scholz
| Developmental neurotoxicity of PBDEs, mechanisms and implications [[electronic resource] /] / Henrik Alm and Birger Scholz |
| Autore | Alm Henrik |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2010 |
| Descrizione fisica | 1 online resource (131 p.) |
| Disciplina | 615.9 |
| Altri autori (Persone) | ScholzBirger |
| Collana | Neuroscience research progress |
| Soggetto topico |
Developmental toxicology
Polybrominated diphenyl ethers - Toxicology Neurotoxic agents |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-61668-602-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Brain development and developmental toxicity -- PBDE exposure and general neurotoxicity -- In vivo mechanisms of PBDE neurotoxicity -- In vitro mechanisms of PBDE neurotoxicity -- Perspectives and future directions. |
| Record Nr. | UNINA-9910457797803321 |
Alm Henrik
|
||
| New York, : Nova Science Publishers, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Developmental neurotoxicity of PBDEs, mechanisms and implications [[electronic resource] /] / Henrik Alm and Birger Scholz
| Developmental neurotoxicity of PBDEs, mechanisms and implications [[electronic resource] /] / Henrik Alm and Birger Scholz |
| Autore | Alm Henrik |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2010 |
| Descrizione fisica | 1 online resource (131 p.) |
| Disciplina | 615.9 |
| Altri autori (Persone) | ScholzBirger |
| Collana | Neuroscience research progress |
| Soggetto topico |
Developmental toxicology
Polybrominated diphenyl ethers - Toxicology Neurotoxic agents |
| ISBN | 1-61668-602-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Brain development and developmental toxicity -- PBDE exposure and general neurotoxicity -- In vivo mechanisms of PBDE neurotoxicity -- In vitro mechanisms of PBDE neurotoxicity -- Perspectives and future directions. |
| Record Nr. | UNINA-9910781649403321 |
|
Alm Henrik
|
||
| New York, : Nova Science Publishers, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Developmental neurotoxicity of PBDEs, mechanisms and implications [[electronic resource] /] / Henrik Alm and Birger Scholz
| Developmental neurotoxicity of PBDEs, mechanisms and implications [[electronic resource] /] / Henrik Alm and Birger Scholz |
| Autore | Alm Henrik |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2010 |
| Descrizione fisica | 1 online resource (131 p.) |
| Disciplina | 615.9 |
| Altri autori (Persone) | ScholzBirger |
| Collana | Neuroscience research progress |
| Soggetto topico |
Developmental toxicology
Polybrominated diphenyl ethers - Toxicology Neurotoxic agents |
| ISBN | 1-61668-602-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Brain development and developmental toxicity -- PBDE exposure and general neurotoxicity -- In vivo mechanisms of PBDE neurotoxicity -- In vitro mechanisms of PBDE neurotoxicity -- Perspectives and future directions. |
| Record Nr. | UNINA-9910816841203321 |
|
Alm Henrik
|
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| New York, : Nova Science Publishers, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neurotoxicity : new advances / / edited by Suna Sabuncuoglu
| Neurotoxicity : new advances / / edited by Suna Sabuncuoglu |
| Pubbl/distr/stampa | London : , : IntechOpen, , 2022 |
| Descrizione fisica | 1 online resource (198 pages) |
| Disciplina | 616.80471 |
| Soggetto topico | Neurotoxic agents |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Neurotoxicity |
| Record Nr. | UNINA-9910688377403321 |
| London : , : IntechOpen, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neurotoxicity research
| Neurotoxicity research |
| Pubbl/distr/stampa | [Amsterdam?], : Harwood Academic Publishers |
| Descrizione fisica | 1 online resource |
| Soggetto topico |
Neurotoxicology
Toxicology Neurotoxic agents Nervous system - Degeneration Nervous system - Regeneration Neurosciences Neurons - drug effects Apoptosis Cytoprotection Nerve Degeneration Nerve Regeneration Neurotoxins |
| Soggetto genere / forma | Periodical |
| ISSN | 1476-3524 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996207254103316 |
| [Amsterdam?], : Harwood Academic Publishers | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Neurotoxicity research
| Neurotoxicity research |
| Pubbl/distr/stampa | [Amsterdam?], : Harwood Academic Publishers |
| Descrizione fisica | 1 online resource |
| Soggetto topico |
Neurotoxicology
Toxicology Neurotoxic agents Nervous system - Degeneration Nervous system - Regeneration Neurosciences Neurons - drug effects Apoptosis Cytoprotection Nerve Degeneration Nerve Regeneration Neurotoxins |
| Soggetto genere / forma | Periodical |
| ISSN | 1476-3524 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910154513103321 |
| [Amsterdam?], : Harwood Academic Publishers | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
