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Astrocyte-Neuron Interactions in Health and Disease / / edited by Elena Blanco-Suarez, Isabella Farhy-Tselnicker
| Astrocyte-Neuron Interactions in Health and Disease / / edited by Elena Blanco-Suarez, Isabella Farhy-Tselnicker |
| Autore | Blanco-Suarez Elena |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (385 pages) |
| Disciplina | 612.8 |
| Altri autori (Persone) | Farhy-TselnickerIsabella |
| Collana | Advances in Neurobiology |
| Soggetto topico |
Neurosciences
Neurophysiology Neurons Neurology Neuroscience Cellular Neuroscience |
| ISBN |
9783031648397
9783031648380 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Evolution of Astrocyte-Neuron Interactions across Species -- Glia in Invertebrate Models: Insights from C. elegans -- Astrocyte Development in the Rodent -- Neuron-Astrocyte Interactions: A Human Perspective -- Gene Expression at the Tripartite Synapse: Bridging the Gap between Neurons and Astrocytes -- Homeostasis to Allostasis: Prefrontal Astrocyte Roles in Cognitive Flexibility and Stress Biology -- Astrocyte-Neuron Interactions in Substance Use Disorders -- Astrocytes in Pain Perception: A Systems Neuroscience Approach -- Astrocyte-Neuron Interaction in Spinal Cord Injury -- Astrocyte Regulation of Neuronal Function and Survival in Stroke Pathophysiology -- The Interplay of Astrocytes and Neurons in Autism Spectrum Disorder -- Astrocyte-Neuron Interactions Contributing to Amyotrophic Lateral Sclerosis Progression -- The Role of Astrocytes in Parkinson’s Disease -- Astrocyte-Neuron Interactions in Alzheimer’s Disease. |
| Record Nr. | UNINA-9910882899303321 |
Blanco-Suarez Elena
|
||
| Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Autophagy of the nervous system [[electronic resource] ] : cellular self-digestion in neurons and neurological diseases / / editors, Zhenyu Yue, Charleen T Chu
| Autophagy of the nervous system [[electronic resource] ] : cellular self-digestion in neurons and neurological diseases / / editors, Zhenyu Yue, Charleen T Chu |
| Pubbl/distr/stampa | Singapore ; ; Hackensack, N.J., : World Scientific Pub., c2012 |
| Descrizione fisica | 1 online resource (441 p.) |
| Disciplina | 571.936 |
| Altri autori (Persone) |
YueZhenyu
Chu. Charleen T |
| Soggetto topico |
Nervous system - Diseases
Neurons |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-283-85069-9
981-4350-45-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
CONTENTS; Contributors; Preface; Section 1 Neuronal Autophagy: Cellular Process and Regulation; Chapter 1 The Cellular Process of Autophagy and Control of Autophagy in Neurons Nicole C. McKnight, Noboru Mizushima and Zhenyu Yue; INTRODUCTION; AUTOPHAGY PATHWAYS; AUTOPHAGY CORE MACHINERY; ULK1/ULK2 Kinase Complex (Atg1); Atg9 Recycling Complex; PI3-Kinase Complexes (Vps34-Beclin 1); Atg18/WIPI PI(3)P-Binding Protein and Atg2; Ubiquitin-like Conjugation Systems; Atg12 conjugation reaction; Atg8/LC3 conjugation reaction; SOURCE OF THE AUTOPHAGOSOME MEMBRANE
AUTOPHAGY SIGNALING/REGULATION OF AUTOPHAGYTHE ROLE OF LC3-BINDING PROTEINS IN AUTOPHAGY; AUTOPHAGY IN NEURONS; Compartmentalized Autophagy in Neurons; Autophagy Signaling in Neurons; Autophagic Clearance of Protein Aggregates in Neurons; Regulation of Neuronal Autophagy by Endosomal and ESCRT Machinery; Neuroprotective versus Neurotoxic Role of Autophagy; AUTOPHAGY IN NEURODEGENERATIVE DISEASES; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 2 Autophagosome Maturation, Endocytosis and Neurodegenerative Disease Ai Yamamoto and Anne Simonsen; INTRODUCTION; MACROAUTOPHAGY A Brief IntroductionAutophagosome Maturation: A Convergence with Endocytosis; Endocytosis; The maturation of an autophagosome to an autolysosome: Fusion with endocytic compartments; Vps34 complexes; Fusion with the lysosome; AUTOPHAGOSOME MATURATION AND NEURODEGENERATION; CONCLUDING REMARKS; REFERENCES; Chapter 3 Cross-Talk Between the Ubiquitin-Proteasome System and Macroautophagy Serhiy Pankiv and Terje Johansen; INTRODUCTION; THE UBIQUITIN-PROTEASOME SYSTEM (UPS); AUTOPHAGY; UPS AND AUTOPHAGY: CROSS-TALK AT THE REGULATORY LEVEL; UPS AND AUTOPHAGY: CROSS-TALK AT THE SUBSTRATE LEVEL CONCLUSIONSREFERENCES; Chapter 4 Chaperone-Mediated Autophagy (CMA) in Neurons Maria Xilouri, Hsiao-Yu Peng and Leonidas Stefanis; INTRODUCTION; MECHANISM OF CMA; CMA IN THE NERVOUS SYSTEM; CMA IN NEURODEGENERATION: THE CASE FOR PARKINSON'S DISEASE; CMA IN OTHER NEURODEGENERATIVE DISEASES; CONCLUSION; ACKNOWLEDGEMENTS AND FUNDING; REFERENCES; Chapter 5 Maintaining Autophagic Balance: A Role for Brakes Salvatore J. Cherra, III and Charleen T. Chu; INTRODUCTION; OVERVIEW OF AUTOPHAGY INDUCTION; NEGATIVE REGULATORS OF AUTOPHAGY INDUCTION; Proteins Regulating Autophagy Induction Mammalian target of rapamycinJumpy (myotubularin related protein 14); Bcl-2 (B cell CLL/lymphoma-2); FLICE-inhibitory proteins; Post-Translational Modifications that Regulate Autophagy Induction; Proteolysis of autophagy proteins; Regulation of autophagy by acetylation; Regulation of autophagy induction by phosphorylation; Regulation of LC3 by phosphorylation; AUTOPHAGY DOWNREGULATING MECHANISMS IN RELATION TO CANONICAL AND NON-CANONICAL INDUCTION PATHWAYS; ROLES OF AUTOPHAGY INHIBITION DURING DISEASE IN THE NERVOUS SYSTEM; CONCLUSION; REFERENCES; Section 2 Autophagy and Neurological Diseases Chapter 6 Autophagy and Its Cross-Talk with Cell Death in Neural Development Sabrina Di Bartolomeo and Francesco Cecconi |
| Record Nr. | UNINA-9910464783203321 |
| Singapore ; ; Hackensack, N.J., : World Scientific Pub., c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Autophagy of the nervous system [[electronic resource] ] : cellular self-digestion in neurons and neurological diseases / / editors, Zhenyu Yue, Charleen T Chu
| Autophagy of the nervous system [[electronic resource] ] : cellular self-digestion in neurons and neurological diseases / / editors, Zhenyu Yue, Charleen T Chu |
| Pubbl/distr/stampa | Singapore ; ; Hackensack, N.J., : World Scientific Pub., c2012 |
| Descrizione fisica | 1 online resource (441 p.) |
| Disciplina | 571.936 |
| Altri autori (Persone) |
YueZhenyu
Chu. Charleen T |
| Soggetto topico |
Nervous system - Diseases
Neurons |
| ISBN |
1-283-85069-9
981-4350-45-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
CONTENTS; Contributors; Preface; Section 1 Neuronal Autophagy: Cellular Process and Regulation; Chapter 1 The Cellular Process of Autophagy and Control of Autophagy in Neurons Nicole C. McKnight, Noboru Mizushima and Zhenyu Yue; INTRODUCTION; AUTOPHAGY PATHWAYS; AUTOPHAGY CORE MACHINERY; ULK1/ULK2 Kinase Complex (Atg1); Atg9 Recycling Complex; PI3-Kinase Complexes (Vps34-Beclin 1); Atg18/WIPI PI(3)P-Binding Protein and Atg2; Ubiquitin-like Conjugation Systems; Atg12 conjugation reaction; Atg8/LC3 conjugation reaction; SOURCE OF THE AUTOPHAGOSOME MEMBRANE
AUTOPHAGY SIGNALING/REGULATION OF AUTOPHAGYTHE ROLE OF LC3-BINDING PROTEINS IN AUTOPHAGY; AUTOPHAGY IN NEURONS; Compartmentalized Autophagy in Neurons; Autophagy Signaling in Neurons; Autophagic Clearance of Protein Aggregates in Neurons; Regulation of Neuronal Autophagy by Endosomal and ESCRT Machinery; Neuroprotective versus Neurotoxic Role of Autophagy; AUTOPHAGY IN NEURODEGENERATIVE DISEASES; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 2 Autophagosome Maturation, Endocytosis and Neurodegenerative Disease Ai Yamamoto and Anne Simonsen; INTRODUCTION; MACROAUTOPHAGY A Brief IntroductionAutophagosome Maturation: A Convergence with Endocytosis; Endocytosis; The maturation of an autophagosome to an autolysosome: Fusion with endocytic compartments; Vps34 complexes; Fusion with the lysosome; AUTOPHAGOSOME MATURATION AND NEURODEGENERATION; CONCLUDING REMARKS; REFERENCES; Chapter 3 Cross-Talk Between the Ubiquitin-Proteasome System and Macroautophagy Serhiy Pankiv and Terje Johansen; INTRODUCTION; THE UBIQUITIN-PROTEASOME SYSTEM (UPS); AUTOPHAGY; UPS AND AUTOPHAGY: CROSS-TALK AT THE REGULATORY LEVEL; UPS AND AUTOPHAGY: CROSS-TALK AT THE SUBSTRATE LEVEL CONCLUSIONSREFERENCES; Chapter 4 Chaperone-Mediated Autophagy (CMA) in Neurons Maria Xilouri, Hsiao-Yu Peng and Leonidas Stefanis; INTRODUCTION; MECHANISM OF CMA; CMA IN THE NERVOUS SYSTEM; CMA IN NEURODEGENERATION: THE CASE FOR PARKINSON'S DISEASE; CMA IN OTHER NEURODEGENERATIVE DISEASES; CONCLUSION; ACKNOWLEDGEMENTS AND FUNDING; REFERENCES; Chapter 5 Maintaining Autophagic Balance: A Role for Brakes Salvatore J. Cherra, III and Charleen T. Chu; INTRODUCTION; OVERVIEW OF AUTOPHAGY INDUCTION; NEGATIVE REGULATORS OF AUTOPHAGY INDUCTION; Proteins Regulating Autophagy Induction Mammalian target of rapamycinJumpy (myotubularin related protein 14); Bcl-2 (B cell CLL/lymphoma-2); FLICE-inhibitory proteins; Post-Translational Modifications that Regulate Autophagy Induction; Proteolysis of autophagy proteins; Regulation of autophagy by acetylation; Regulation of autophagy induction by phosphorylation; Regulation of LC3 by phosphorylation; AUTOPHAGY DOWNREGULATING MECHANISMS IN RELATION TO CANONICAL AND NON-CANONICAL INDUCTION PATHWAYS; ROLES OF AUTOPHAGY INHIBITION DURING DISEASE IN THE NERVOUS SYSTEM; CONCLUSION; REFERENCES; Section 2 Autophagy and Neurological Diseases Chapter 6 Autophagy and Its Cross-Talk with Cell Death in Neural Development Sabrina Di Bartolomeo and Francesco Cecconi |
| Record Nr. | UNINA-9910789348503321 |
| Singapore ; ; Hackensack, N.J., : World Scientific Pub., c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Autophagy of the nervous system : cellular self-digestion in neurons and neurological diseases / / editors, Zhenyu Yue, Charleen T Chu
| Autophagy of the nervous system : cellular self-digestion in neurons and neurological diseases / / editors, Zhenyu Yue, Charleen T Chu |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Singapore ; ; Hackensack, N.J., : World Scientific Pub., c2012 |
| Descrizione fisica | 1 online resource (441 p.) |
| Disciplina | 571.936 |
| Altri autori (Persone) |
YueZhenyu
Chu. Charleen T |
| Soggetto topico |
Nervous system - Diseases
Neurons |
| ISBN |
1-283-85069-9
981-4350-45-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
CONTENTS; Contributors; Preface; Section 1 Neuronal Autophagy: Cellular Process and Regulation; Chapter 1 The Cellular Process of Autophagy and Control of Autophagy in Neurons Nicole C. McKnight, Noboru Mizushima and Zhenyu Yue; INTRODUCTION; AUTOPHAGY PATHWAYS; AUTOPHAGY CORE MACHINERY; ULK1/ULK2 Kinase Complex (Atg1); Atg9 Recycling Complex; PI3-Kinase Complexes (Vps34-Beclin 1); Atg18/WIPI PI(3)P-Binding Protein and Atg2; Ubiquitin-like Conjugation Systems; Atg12 conjugation reaction; Atg8/LC3 conjugation reaction; SOURCE OF THE AUTOPHAGOSOME MEMBRANE
AUTOPHAGY SIGNALING/REGULATION OF AUTOPHAGYTHE ROLE OF LC3-BINDING PROTEINS IN AUTOPHAGY; AUTOPHAGY IN NEURONS; Compartmentalized Autophagy in Neurons; Autophagy Signaling in Neurons; Autophagic Clearance of Protein Aggregates in Neurons; Regulation of Neuronal Autophagy by Endosomal and ESCRT Machinery; Neuroprotective versus Neurotoxic Role of Autophagy; AUTOPHAGY IN NEURODEGENERATIVE DISEASES; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 2 Autophagosome Maturation, Endocytosis and Neurodegenerative Disease Ai Yamamoto and Anne Simonsen; INTRODUCTION; MACROAUTOPHAGY A Brief IntroductionAutophagosome Maturation: A Convergence with Endocytosis; Endocytosis; The maturation of an autophagosome to an autolysosome: Fusion with endocytic compartments; Vps34 complexes; Fusion with the lysosome; AUTOPHAGOSOME MATURATION AND NEURODEGENERATION; CONCLUDING REMARKS; REFERENCES; Chapter 3 Cross-Talk Between the Ubiquitin-Proteasome System and Macroautophagy Serhiy Pankiv and Terje Johansen; INTRODUCTION; THE UBIQUITIN-PROTEASOME SYSTEM (UPS); AUTOPHAGY; UPS AND AUTOPHAGY: CROSS-TALK AT THE REGULATORY LEVEL; UPS AND AUTOPHAGY: CROSS-TALK AT THE SUBSTRATE LEVEL CONCLUSIONSREFERENCES; Chapter 4 Chaperone-Mediated Autophagy (CMA) in Neurons Maria Xilouri, Hsiao-Yu Peng and Leonidas Stefanis; INTRODUCTION; MECHANISM OF CMA; CMA IN THE NERVOUS SYSTEM; CMA IN NEURODEGENERATION: THE CASE FOR PARKINSON'S DISEASE; CMA IN OTHER NEURODEGENERATIVE DISEASES; CONCLUSION; ACKNOWLEDGEMENTS AND FUNDING; REFERENCES; Chapter 5 Maintaining Autophagic Balance: A Role for Brakes Salvatore J. Cherra, III and Charleen T. Chu; INTRODUCTION; OVERVIEW OF AUTOPHAGY INDUCTION; NEGATIVE REGULATORS OF AUTOPHAGY INDUCTION; Proteins Regulating Autophagy Induction Mammalian target of rapamycinJumpy (myotubularin related protein 14); Bcl-2 (B cell CLL/lymphoma-2); FLICE-inhibitory proteins; Post-Translational Modifications that Regulate Autophagy Induction; Proteolysis of autophagy proteins; Regulation of autophagy by acetylation; Regulation of autophagy induction by phosphorylation; Regulation of LC3 by phosphorylation; AUTOPHAGY DOWNREGULATING MECHANISMS IN RELATION TO CANONICAL AND NON-CANONICAL INDUCTION PATHWAYS; ROLES OF AUTOPHAGY INHIBITION DURING DISEASE IN THE NERVOUS SYSTEM; CONCLUSION; REFERENCES; Section 2 Autophagy and Neurological Diseases Chapter 6 Autophagy and Its Cross-Talk with Cell Death in Neural Development Sabrina Di Bartolomeo and Francesco Cecconi |
| Record Nr. | UNINA-9910827766603321 |
| Singapore ; ; Hackensack, N.J., : World Scientific Pub., c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biophysics of computation [[electronic resource] ] : information processing in single neurons / / Christof Koch
| Biophysics of computation [[electronic resource] ] : information processing in single neurons / / Christof Koch |
| Autore | Koch Christof <1956-> |
| Pubbl/distr/stampa | New York, : Oxford University Press, 1999 |
| Descrizione fisica | 1 online resource (587 p.) |
| Disciplina | 573.8/536 |
| Collana | Computational neuroscience |
| Soggetto topico |
Computational neuroscience
Neurons Neural networks (Neurobiology) Action potentials (Electrophysiology) Neural conduction |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-19-756233-7
1-280-59509-4 9786613624925 0-19-976055-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Contents; Preface; List of Symbols; Introduction; 1 The Membrane Equation; 1.1 Structure of the Passive Neuronal Membrane; 1.1.1 Resting Potential; 1.1.2 Membrane Capacity; 1.1.3 Membrane Resistance; 1.2 A Simple RC Circuit; 1.3 RC Circuits as Linear Systems; 1.3.1 Filtering by RC Circuits; 1.4 Synaptic Input; 1.5 Synaptic Input Is Nonlinear; 1.5.1 Synaptic Input, Saturation, and the Membrane Time Constant; 1.5.2 Synaptic Interactions among Excitation and Shunting Inhibition; 1.5.3 Gain Normalization in Visual Cortex and Synaptic Input; 1.6 Recapitulation; 2 Linear Cable Theory
2.1 Basic Assumptions Underlying One-Dimensional Cable Theory2.1.1 Linear Cable Equation; 2.2 Steady-State Solutions; 2.2.1 Infinite Cable; 2.2.2 Finite Cable; 2.3 Time-Dependent Solutions; 2.3.1 Infinite Cable; 2.3.2 Finite Cable; 2.4 Neuronal Delays and Propagation Velocity; 2.5 Recapitulation; 3 Passive Dendritic Trees; 3.1 Branched Cables; 3.1.1 What Happens at Branch Points?; 3.2 Equivalent Cylinder; 3.3 Solving the Linear Cable Equation for Branched Structures; 3.3.1 Exact Methods; 3.3.2 Compartmental Modeling; 3.4 Transfer Resistances; 3.4.1 General Definition; 3.4.2 An Example 3.4.3 Properties of K[sub(ij)]3.4.4 Transfer Resistances in a Pyramidal Cell; 3.5 Measures of Synaptic Efficiency; 3.5.1 Electrotonic Distance; 3.5.2 Voltage Attenuation; 3.5.3 Charge Attenuation; 3.5.4 Graphical Morphoelectrotonic Transforms; 3.6 Signal Delays in Dendritic Trees; 3.6.1 Experimental Determination of T[sub(m)]; 3.6.2 Local and Propagation Delays in Dendritic Trees; 3.6.3 Dependence of Fast Synaptic Inputs on Cable Parameters; 3.7 Recapitulation; 4 Synaptic Input; 4.1 Neuronal and Synaptic Packing Densities; 4.2 Synaptic Transmission Is Stochastic 4.2.1 Probability of Synaptic Release p4.2.2 What Is the Synaptic Weight?; 4.3 Neurotransmitters; 4.4 Synaptic Receptors; 4.5 Synaptic Input as Conductance Change; 4.5.1 Synaptic Reversal Potential in Series with an Increase in Conductance; 4.5.2 Conductance Decreasing Synapses; 4.6 Excitatory NMDA and Non-NMDA Synaptic Input; 4.7 Inhibitory GABAergic Synaptic Input; 4.8 Postsynaptic Potential; 4.8.1 Stationary Synaptic Input; 4.8.2 Transient Synaptic Input; 4.8.3 Infinitely Fast Synaptic Input; 4.9 Visibility of Synaptic Inputs; 4.9.1 Input Impedance in the Presence of Synaptic Input 4.10 Electrical Gap Junctions4.11 Recapitulation; 5 Synaptic Interactions in a Passive Dendritic Tree; 5.1 Nonlinear Interaction among Excitation and Inhibition; 5.1.1 Absolute versus Relative Suppression; 5.1.2 General Analysis of Synaptic Interaction in a Passive Tree; 5.1.3 Location of the Inhibitory Synapse; 5.1.4 Shunting Inhibition Implements a ""Dirty"" Multiplication; 5.1.5 Hyperpolarizing Inhibition Acts Like a Linear Subtraction; 5.1.6 Functional Interpretation of the Synaptic Architecture and Dendritic Morphology: AND-NOT Gates 5.1.7 Retinal Directional Selectivity and Synaptic Logic |
| Record Nr. | UNINA-9910457836903321 |
|
Koch Christof <1956->
|
||
| New York, : Oxford University Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biophysics of computation [[electronic resource] ] : information processing in single neurons / / Christof Koch
| Biophysics of computation [[electronic resource] ] : information processing in single neurons / / Christof Koch |
| Autore | Koch Christof <1956-> |
| Pubbl/distr/stampa | New York, : Oxford University Press, 1999 |
| Descrizione fisica | 1 online resource (587 p.) |
| Disciplina | 573.8/536 |
| Collana | Computational neuroscience |
| Soggetto topico |
Computational neuroscience
Neurons Neural networks (Neurobiology) Action potentials (Electrophysiology) Neural conduction |
| ISBN |
0-19-029285-7
0-19-756233-7 1-280-59509-4 9786613624925 0-19-976055-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Contents; Preface; List of Symbols; Introduction; 1 The Membrane Equation; 1.1 Structure of the Passive Neuronal Membrane; 1.1.1 Resting Potential; 1.1.2 Membrane Capacity; 1.1.3 Membrane Resistance; 1.2 A Simple RC Circuit; 1.3 RC Circuits as Linear Systems; 1.3.1 Filtering by RC Circuits; 1.4 Synaptic Input; 1.5 Synaptic Input Is Nonlinear; 1.5.1 Synaptic Input, Saturation, and the Membrane Time Constant; 1.5.2 Synaptic Interactions among Excitation and Shunting Inhibition; 1.5.3 Gain Normalization in Visual Cortex and Synaptic Input; 1.6 Recapitulation; 2 Linear Cable Theory
2.1 Basic Assumptions Underlying One-Dimensional Cable Theory2.1.1 Linear Cable Equation; 2.2 Steady-State Solutions; 2.2.1 Infinite Cable; 2.2.2 Finite Cable; 2.3 Time-Dependent Solutions; 2.3.1 Infinite Cable; 2.3.2 Finite Cable; 2.4 Neuronal Delays and Propagation Velocity; 2.5 Recapitulation; 3 Passive Dendritic Trees; 3.1 Branched Cables; 3.1.1 What Happens at Branch Points?; 3.2 Equivalent Cylinder; 3.3 Solving the Linear Cable Equation for Branched Structures; 3.3.1 Exact Methods; 3.3.2 Compartmental Modeling; 3.4 Transfer Resistances; 3.4.1 General Definition; 3.4.2 An Example 3.4.3 Properties of K[sub(ij)]3.4.4 Transfer Resistances in a Pyramidal Cell; 3.5 Measures of Synaptic Efficiency; 3.5.1 Electrotonic Distance; 3.5.2 Voltage Attenuation; 3.5.3 Charge Attenuation; 3.5.4 Graphical Morphoelectrotonic Transforms; 3.6 Signal Delays in Dendritic Trees; 3.6.1 Experimental Determination of T[sub(m)]; 3.6.2 Local and Propagation Delays in Dendritic Trees; 3.6.3 Dependence of Fast Synaptic Inputs on Cable Parameters; 3.7 Recapitulation; 4 Synaptic Input; 4.1 Neuronal and Synaptic Packing Densities; 4.2 Synaptic Transmission Is Stochastic 4.2.1 Probability of Synaptic Release p4.2.2 What Is the Synaptic Weight?; 4.3 Neurotransmitters; 4.4 Synaptic Receptors; 4.5 Synaptic Input as Conductance Change; 4.5.1 Synaptic Reversal Potential in Series with an Increase in Conductance; 4.5.2 Conductance Decreasing Synapses; 4.6 Excitatory NMDA and Non-NMDA Synaptic Input; 4.7 Inhibitory GABAergic Synaptic Input; 4.8 Postsynaptic Potential; 4.8.1 Stationary Synaptic Input; 4.8.2 Transient Synaptic Input; 4.8.3 Infinitely Fast Synaptic Input; 4.9 Visibility of Synaptic Inputs; 4.9.1 Input Impedance in the Presence of Synaptic Input 4.10 Electrical Gap Junctions4.11 Recapitulation; 5 Synaptic Interactions in a Passive Dendritic Tree; 5.1 Nonlinear Interaction among Excitation and Inhibition; 5.1.1 Absolute versus Relative Suppression; 5.1.2 General Analysis of Synaptic Interaction in a Passive Tree; 5.1.3 Location of the Inhibitory Synapse; 5.1.4 Shunting Inhibition Implements a ""Dirty"" Multiplication; 5.1.5 Hyperpolarizing Inhibition Acts Like a Linear Subtraction; 5.1.6 Functional Interpretation of the Synaptic Architecture and Dendritic Morphology: AND-NOT Gates 5.1.7 Retinal Directional Selectivity and Synaptic Logic |
| Record Nr. | UNINA-9910779059703321 |
|
Koch Christof <1956->
|
||
| New York, : Oxford University Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biophysics of computation : information processing in single neurons / / Christof Koch
| Biophysics of computation : information processing in single neurons / / Christof Koch |
| Autore | Koch Christof <1956-> |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | New York, : Oxford University Press, 1999 |
| Descrizione fisica | 1 online resource (587 p.) |
| Disciplina |
573.8/536
573.8536 |
| Collana | Computational neuroscience |
| Soggetto topico |
Computational neuroscience
Neurons Neural networks (Neurobiology) Action potentials (Electrophysiology) Neural conduction |
| ISBN |
0-19-029285-7
0-19-756233-7 1-280-59509-4 9786613624925 0-19-976055-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Contents; Preface; List of Symbols; Introduction; 1 The Membrane Equation; 1.1 Structure of the Passive Neuronal Membrane; 1.1.1 Resting Potential; 1.1.2 Membrane Capacity; 1.1.3 Membrane Resistance; 1.2 A Simple RC Circuit; 1.3 RC Circuits as Linear Systems; 1.3.1 Filtering by RC Circuits; 1.4 Synaptic Input; 1.5 Synaptic Input Is Nonlinear; 1.5.1 Synaptic Input, Saturation, and the Membrane Time Constant; 1.5.2 Synaptic Interactions among Excitation and Shunting Inhibition; 1.5.3 Gain Normalization in Visual Cortex and Synaptic Input; 1.6 Recapitulation; 2 Linear Cable Theory
2.1 Basic Assumptions Underlying One-Dimensional Cable Theory2.1.1 Linear Cable Equation; 2.2 Steady-State Solutions; 2.2.1 Infinite Cable; 2.2.2 Finite Cable; 2.3 Time-Dependent Solutions; 2.3.1 Infinite Cable; 2.3.2 Finite Cable; 2.4 Neuronal Delays and Propagation Velocity; 2.5 Recapitulation; 3 Passive Dendritic Trees; 3.1 Branched Cables; 3.1.1 What Happens at Branch Points?; 3.2 Equivalent Cylinder; 3.3 Solving the Linear Cable Equation for Branched Structures; 3.3.1 Exact Methods; 3.3.2 Compartmental Modeling; 3.4 Transfer Resistances; 3.4.1 General Definition; 3.4.2 An Example 3.4.3 Properties of K[sub(ij)]3.4.4 Transfer Resistances in a Pyramidal Cell; 3.5 Measures of Synaptic Efficiency; 3.5.1 Electrotonic Distance; 3.5.2 Voltage Attenuation; 3.5.3 Charge Attenuation; 3.5.4 Graphical Morphoelectrotonic Transforms; 3.6 Signal Delays in Dendritic Trees; 3.6.1 Experimental Determination of T[sub(m)]; 3.6.2 Local and Propagation Delays in Dendritic Trees; 3.6.3 Dependence of Fast Synaptic Inputs on Cable Parameters; 3.7 Recapitulation; 4 Synaptic Input; 4.1 Neuronal and Synaptic Packing Densities; 4.2 Synaptic Transmission Is Stochastic 4.2.1 Probability of Synaptic Release p4.2.2 What Is the Synaptic Weight?; 4.3 Neurotransmitters; 4.4 Synaptic Receptors; 4.5 Synaptic Input as Conductance Change; 4.5.1 Synaptic Reversal Potential in Series with an Increase in Conductance; 4.5.2 Conductance Decreasing Synapses; 4.6 Excitatory NMDA and Non-NMDA Synaptic Input; 4.7 Inhibitory GABAergic Synaptic Input; 4.8 Postsynaptic Potential; 4.8.1 Stationary Synaptic Input; 4.8.2 Transient Synaptic Input; 4.8.3 Infinitely Fast Synaptic Input; 4.9 Visibility of Synaptic Inputs; 4.9.1 Input Impedance in the Presence of Synaptic Input 4.10 Electrical Gap Junctions4.11 Recapitulation; 5 Synaptic Interactions in a Passive Dendritic Tree; 5.1 Nonlinear Interaction among Excitation and Inhibition; 5.1.1 Absolute versus Relative Suppression; 5.1.2 General Analysis of Synaptic Interaction in a Passive Tree; 5.1.3 Location of the Inhibitory Synapse; 5.1.4 Shunting Inhibition Implements a ""Dirty"" Multiplication; 5.1.5 Hyperpolarizing Inhibition Acts Like a Linear Subtraction; 5.1.6 Functional Interpretation of the Synaptic Architecture and Dendritic Morphology: AND-NOT Gates 5.1.7 Retinal Directional Selectivity and Synaptic Logic |
| Record Nr. | UNINA-9910825116003321 |
|
Koch Christof <1956->
|
||
| New York, : Oxford University Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Brain cell biology
| Brain cell biology |
| Pubbl/distr/stampa | [New York], : Springer |
| Disciplina | 611.8 |
| Soggetto topico |
Neurobiology
Neurons Cells Brain Cytology Brain - Cytology Neurophysiology Brain - cytology Neurobiologie Neurones Cellules Cerveau Cytologie Cerveau - Cytologie Neurophysiologie |
| Soggetto genere / forma | Periodicals. |
| ISSN | 1559-7113 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910145605803321 |
| [New York], : Springer | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Brain cell biology
| Brain cell biology |
| Pubbl/distr/stampa | [New York], : Springer |
| Disciplina | 611.8 |
| Soggetto topico |
Neurobiology
Neurons Cells Brain Cytology Brain - Cytology Neurophysiology Brain - cytology Neurobiologie Neurones Cellules Cerveau Cytologie Cerveau - Cytologie Neurophysiologie |
| Soggetto genere / forma | Periodicals. |
| ISSN | 1559-7113 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996204900903316 |
| [New York], : Springer | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
The brain's response to opiates
| The brain's response to opiates |
| Pubbl/distr/stampa | [Bethesda, Md.?] : , : National Institute on Drug Abuse, National Institutes of Health, U.S. Dept. of Health and Human Services, , 1997 |
| Descrizione fisica | 1 online resource (2 unnumbered pages) : color illustrations |
| Collana |
Mind over matter
NIH publication |
| Soggetto topico |
Narcotics - Research
Endorphins - Receptors Central nervous system depressants Youth - Drug use - Prevention Neurons |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910699061803321 |
| [Bethesda, Md.?] : , : National Institute on Drug Abuse, National Institutes of Health, U.S. Dept. of Health and Human Services, , 1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Neurons
(82)
- Neurophysiology (17)
- Cytology (10)
- Molecular neurobiology (9)
- Neurology (7)